{"id":"https://openalex.org/W2059912464","doi":"https://doi.org/10.1161/01.atv.15.1.128","title":"Collagen-Induced Thrombus Formation in Flowing Nonanticoagulated Human Blood From Habitual Smokers and Nonsmoking Patients With Severe Peripheral Atherosclerotic Disease","display_name":"Collagen-Induced Thrombus Formation in Flowing Nonanticoagulated Human Blood From Habitual Smokers and Nonsmoking Patients With Severe Peripheral Atherosclerotic Disease","publication_year":1995,"publication_date":"1995-01-01","ids":{"openalex":"https://openalex.org/W2059912464","doi":"https://doi.org/10.1161/01.atv.15.1.128","mag":"2059912464","pmid":"https://pubmed.ncbi.nlm.nih.gov/7749808"},"language":"en","primary_location":{"id":"doi:10.1161/01.atv.15.1.128","doi":"https://doi.org/10.1161/01.atv.15.1.128","is_oa":true,"landing_page_url":"https://doi.org/10.1161/01.atv.15.1.128","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.ATV.15.1.128","source":{"id":"https://openalex.org/S3485792","display_name":"Arteriosclerosis Thrombosis and Vascular Biology","issn_l":"1079-5642","issn":["1079-5642","1524-4636"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arteriosclerosis, Thrombosis, and Vascular Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.ATV.15.1.128","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083453339","display_name":"Helge Einar Roald","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Helge E. Roald","raw_affiliation_strings":["From the Faculty of Medicine, University of Oslo (H.E.R.); Research Forum, Ullevaal University Hospital (T.L.); the Department of Surgery, Ullevaal University Hospital (H.D.); Nycomed Bioreg AS (M.H., K.S.S.); the Clinical Chemistry Department, Ullevaal University Hospital (P.K., A.-B.W.); and the Department of Biology, Division of General Physiology, University of Oslo (K.S.S.), Oslo, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Faculty of Medicine, University of Oslo (H.E.R.); Research Forum, Ullevaal University Hospital (T.L.); the Department of Surgery, Ullevaal University Hospital (H.D.); Nycomed Bioreg AS (M.H., K.S.S.); the Clinical Chemistry Department, Ullevaal University Hospital (P.K., A.-B.W.); and the Department of Biology, Division of General Physiology, University of Oslo (K.S.S.), Oslo, Norway","institution_ids":["https://openalex.org/I184942183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040049126","display_name":"Torstein Lyberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Torstein Lyberg","raw_affiliation_strings":["From the Faculty of Medicine, University of Oslo (H.E.R.); Research Forum, Ullevaal University Hospital (T.L.); the Department of Surgery, Ullevaal University Hospital (H.D.); Nycomed Bioreg AS (M.H., K.S.S.); the Clinical Chemistry Department, Ullevaal University Hospital (P.K., A.-B.W.); and the Department of Biology, Division of General Physiology, University of Oslo (K.S.S.), Oslo, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Faculty of Medicine, University of Oslo (H.E.R.); Research Forum, Ullevaal University Hospital (T.L.); the Department of Surgery, Ullevaal University Hospital (H.D.); Nycomed Bioreg AS (M.H., K.S.S.); the Clinical Chemistry Department, Ullevaal University Hospital (P.K., A.-B.W.); and the Department of Biology, Division of General Physiology, University of Oslo (K.S.S.), Oslo, Norway","institution_ids":["https://openalex.org/I184942183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022908510","display_name":"Henrik Dedichen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Henrik Dedichen","raw_affiliation_strings":["From the Faculty of Medicine, University of Oslo (H.E.R.); Research Forum, Ullevaal University Hospital (T.L.); the Department of Surgery, Ullevaal University Hospital (H.D.); Nycomed Bioreg AS (M.H., K.S.S.); the Clinical Chemistry Department, Ullevaal University Hospital (P.K., A.-B.W.); and the Department of Biology, Division of General Physiology, University of Oslo (K.S.S.), Oslo, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Faculty of Medicine, University of Oslo (H.E.R.); Research Forum, Ullevaal University Hospital (T.L.); the Department of Surgery, Ullevaal University Hospital (H.D.); Nycomed Bioreg AS (M.H., K.S.S.); the Clinical Chemistry Department, Ullevaal University Hospital (P.K., A.-B.W.); and the Department of Biology, Division of General Physiology, University of Oslo (K.S.S.), Oslo, Norway","institution_ids":["https://openalex.org/I184942183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110115431","display_name":"M. J. A. G. Hamers","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Marjo Hamers","raw_affiliation_strings":["From the Faculty of Medicine, University of Oslo (H.E.R.); Research Forum, Ullevaal University Hospital (T.L.); the Department of Surgery, Ullevaal University Hospital (H.D.); Nycomed Bioreg AS (M.H., K.S.S.); the Clinical Chemistry Department, Ullevaal University Hospital (P.K., A.-B.W.); and the Department of Biology, Division of General Physiology, University of Oslo (K.S.S.), Oslo, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Faculty of Medicine, University of Oslo (H.E.R.); Research Forum, Ullevaal University Hospital (T.L.); the Department of Surgery, Ullevaal University Hospital (H.D.); Nycomed Bioreg AS (M.H., K.S.S.); the Clinical Chemistry Department, Ullevaal University Hospital (P.K., A.-B.W.); and the Department of Biology, Division of General Physiology, University of Oslo (K.S.S.), Oslo, Norway","institution_ids":["https://openalex.org/I184942183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083337086","display_name":"Peter Kierulf","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Peter Kierulf","raw_affiliation_strings":["From the Faculty of Medicine, University of Oslo (H.E.R.); Research Forum, Ullevaal University Hospital (T.L.); the Department of Surgery, Ullevaal University Hospital (H.D.); Nycomed Bioreg AS (M.H., K.S.S.); the Clinical Chemistry Department, Ullevaal University Hospital (P.K., A.-B.W.); and the Department of Biology, Division of General Physiology, University of Oslo (K.S.S.), Oslo, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Faculty of Medicine, University of Oslo (H.E.R.); Research Forum, Ullevaal University Hospital (T.L.); the Department of Surgery, Ullevaal University Hospital (H.D.); Nycomed Bioreg AS (M.H., K.S.S.); the Clinical Chemistry Department, Ullevaal University Hospital (P.K., A.-B.W.); and the Department of Biology, Division of General Physiology, University of Oslo (K.S.S.), Oslo, Norway","institution_ids":["https://openalex.org/I184942183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112818016","display_name":"\u00c5se-Brit Westvik","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"A\u030ase-Brit Westvik","raw_affiliation_strings":["From the Faculty of Medicine, University of Oslo (H.E.R.); Research Forum, Ullevaal University Hospital (T.L.); the Department of Surgery, Ullevaal University Hospital (H.D.); Nycomed Bioreg AS (M.H., K.S.S.); the Clinical Chemistry Department, Ullevaal University Hospital (P.K., A.-B.W.); and the Department of Biology, Division of General Physiology, University of Oslo (K.S.S.), Oslo, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Faculty of Medicine, University of Oslo (H.E.R.); Research Forum, Ullevaal University Hospital (T.L.); the Department of Surgery, Ullevaal University Hospital (H.D.); Nycomed Bioreg AS (M.H., K.S.S.); the Clinical Chemistry Department, Ullevaal University Hospital (P.K., A.-B.W.); and the Department of Biology, Division of General Physiology, University of Oslo (K.S.S.), Oslo, Norway","institution_ids":["https://openalex.org/I184942183"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111738488","display_name":"Kjell S. Sakar\u00edassen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Kjell S. Sakariassen","raw_affiliation_strings":["From the Faculty of Medicine, University of Oslo (H.E.R.); Research Forum, Ullevaal University Hospital (T.L.); the Department of Surgery, Ullevaal University Hospital (H.D.); Nycomed Bioreg AS (M.H., K.S.S.); the Clinical Chemistry Department, Ullevaal University Hospital (P.K., A.-B.W.); and the Department of Biology, Division of General Physiology, University of Oslo (K.S.S.), Oslo, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Faculty of Medicine, University of Oslo (H.E.R.); Research Forum, Ullevaal University Hospital (T.L.); the Department of Surgery, Ullevaal University Hospital (H.D.); Nycomed Bioreg AS (M.H., K.S.S.); the Clinical Chemistry Department, Ullevaal University Hospital (P.K., A.-B.W.); and the Department of Biology, Division of General Physiology, University of Oslo (K.S.S.), Oslo, Norway","institution_ids":["https://openalex.org/I184942183"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I184942183"],"apc_list":null,"apc_paid":null,"fwci":0.4496,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.61630567,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"15","issue":"1","first_page":"128","last_page":"132"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.774399995803833,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.774399995803833,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.1137000024318695,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11721","display_name":"Blood properties and coagulation","score":0.07970000058412552,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/platelet-thrombus-formation","display_name":"platelet thrombus formation","score":0.8769999742507935},{"id":"https://openalex.org/keywords/smoking","display_name":"smoking","score":0.7879999876022339},{"id":"https://openalex.org/keywords/peripheral-atherosclerosis","display_name":"peripheral atherosclerosis","score":0.796999990940094},{"id":"https://openalex.org/keywords/wall-shear-rate","display_name":"wall shear rate","score":0.7139999866485596},{"id":"https://openalex.org/keywords/fibrinopeptide-a","display_name":"fibrinopeptide A","score":0.890999972820282},{"id":"https://openalex.org/keywords/fibrinogen","display_name":"fibrinogen","score":0.9210000038146973},{"id":"https://openalex.org/keywords/platelet-reactivity","display_name":"platelet reactivity","score":0.9229999780654907},{"id":"https://openalex.org/keywords/cigarette-smoking","display_name":"cigarette smoking","score":0.44600000977516174}],"concepts":[{"id":"https://openalex.org/C2781362458","wikidata":"https://www.wikidata.org/wiki/Q1588755","display_name":"Thrombus","level":2,"score":0.7069933414459229},{"id":"https://openalex.org/C46762472","wikidata":"https://www.wikidata.org/wiki/Q178648","display_name":"Peripheral","level":2,"score":0.6741675734519958},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6694045066833496},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.629718542098999},{"id":"https://openalex.org/C3017910909","wikidata":"https://www.wikidata.org/wiki/Q618363","display_name":"Peripheral blood","level":2,"score":0.5117921233177185},{"id":"https://openalex.org/C3018348675","wikidata":"https://www.wikidata.org/wiki/Q4797557","display_name":"Arterial disease","level":3,"score":0.4988281726837158},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.42303550243377686},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3338889479637146},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.33299678564071655},{"id":"https://openalex.org/C2777466421","wikidata":"https://www.wikidata.org/wiki/Q1266890","display_name":"Vascular disease","level":2,"score":0.2842687666416168}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001161","descriptor_name":"Arteriosclerosis","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D003094","descriptor_name":"Collagen","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D006403","descriptor_name":"Hematologic Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010973","descriptor_name":"Platelet Adhesiveness","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D013927","descriptor_name":"Thrombosis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D016491","descriptor_name":"Peripheral Vascular Diseases","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1161/01.atv.15.1.128","doi":"https://doi.org/10.1161/01.atv.15.1.128","is_oa":true,"landing_page_url":"https://doi.org/10.1161/01.atv.15.1.128","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.ATV.15.1.128","source":{"id":"https://openalex.org/S3485792","display_name":"Arteriosclerosis Thrombosis and Vascular Biology","issn_l":"1079-5642","issn":["1079-5642","1524-4636"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arteriosclerosis, Thrombosis, and Vascular Biology","raw_type":"journal-article"},{"id":"pmid:7749808","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7749808","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arteriosclerosis, thrombosis, and vascular biology","raw_type":"Comparative Study"}],"best_oa_location":{"id":"doi:10.1161/01.atv.15.1.128","doi":"https://doi.org/10.1161/01.atv.15.1.128","is_oa":true,"landing_page_url":"https://doi.org/10.1161/01.atv.15.1.128","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.ATV.15.1.128","source":{"id":"https://openalex.org/S3485792","display_name":"Arteriosclerosis Thrombosis and Vascular Biology","issn_l":"1079-5642","issn":["1079-5642","1524-4636"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arteriosclerosis, Thrombosis, and Vascular Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2059912464.pdf","grobid_xml":"https://content.openalex.org/works/W2059912464.grobid-xml"},"referenced_works_count":32,"referenced_works":["https://openalex.org/W72055241","https://openalex.org/W118974985","https://openalex.org/W562330636","https://openalex.org/W999465543","https://openalex.org/W1565263903","https://openalex.org/W1599055297","https://openalex.org/W1969559107","https://openalex.org/W1978039741","https://openalex.org/W2010709957","https://openalex.org/W2012690187","https://openalex.org/W2012714864","https://openalex.org/W2014912220","https://openalex.org/W2023210284","https://openalex.org/W2061465408","https://openalex.org/W2061755142","https://openalex.org/W2065447230","https://openalex.org/W2069224508","https://openalex.org/W2072414021","https://openalex.org/W2072603754","https://openalex.org/W2139672444","https://openalex.org/W2164550955","https://openalex.org/W2298665163","https://openalex.org/W2319834083","https://openalex.org/W2340429751","https://openalex.org/W2395258381","https://openalex.org/W2409188695","https://openalex.org/W2418202489","https://openalex.org/W2422874157","https://openalex.org/W2428798470","https://openalex.org/W2431768466","https://openalex.org/W2571488753","https://openalex.org/W2886751483"],"related_works":["https://openalex.org/W2413466041","https://openalex.org/W2072603754","https://openalex.org/W4296540947","https://openalex.org/W2116481850","https://openalex.org/W1585667212","https://openalex.org/W2046851405","https://openalex.org/W2419183002","https://openalex.org/W1974327720","https://openalex.org/W7098614086","https://openalex.org/W61039319"],"abstract_inverted_index":{"The":[0,62],"objective":[1],"of":[2,95,169,181,210],"the":[3,67,124,131,139,167,170,191,222],"present":[4],"study":[5],"was":[6,35,127,142,159,165,186],"to":[7,72,99],"investigate":[8],"collagen-induced":[9],"platelet":[10,212],"thrombus":[11,104,119],"formation":[12,86,105,148],"at":[13,66,130,183],"arterial":[14],"blood":[15,20,39,88,107,122,150,189,217],"flow":[16],"conditions":[17],"in":[18,37,57,75,87,106,121,149,188,214,221],"nonanticoagulated":[19,216],"from":[21,25,42,89,103,108,123,151,190],"habitual":[22,90,223],"smokers":[23,91,224],"and":[24,79,197],"nonsmoking":[26,152,171],"patients":[27,153,193],"with":[28,154,199],"severe":[29,155],"peripheral":[30,156],"atherosclerotic":[31,157,192],"disease.":[32],"Collagen-induced":[33],"thrombogenesis":[34],"elicited":[36],"native":[38],"drawn":[40],"directly":[41],"an":[43],"antecubital":[44],"vein":[45],"over":[46],"immobilized":[47],"type":[48],"III":[49],"collagen":[50,68],"fibrils":[51],"coated":[52],"on":[53],"a":[54,58,114,200,230],"coverslip":[55],"positioned":[56],"parallel-plate":[59],"perfusion":[60,182],"chamber.":[61],"wall":[63],"shear":[64,133],"rates":[65],"surface":[69],"were":[70,218],"comparable":[71],"those":[73],"encountered":[74,219],"medium-sized":[76],"(650":[77],"s-1)":[78,83],"moderately":[80],"stenosed":[81],"(2600":[82],"arteries.":[84],"Thrombus":[85,147],"after":[92,113,145,178,226],"10":[93],"hours":[94],"smoking":[96],"abstinence":[97],"appeared":[98],"be":[100],"not":[101],"different":[102],"healthy":[109],"nonsmokers.":[110],"However,":[111,174],"immediately":[112,225],"cigarette":[115],"had":[116,228],"been":[117],"smoked,":[118],"volume":[120],"same":[125],"individuals":[126],"increased":[128],"twofold":[129],"highest":[132],"rate":[134],"(P":[135,194,205],"<":[136,195,206],".05).":[137],"Thus,":[138,208],"thrombotic":[140],"response":[141],"temporarily":[143],"upregulated":[144],"smoking.":[146],"disease":[158],"neither":[160],"enhanced":[161],"nor":[162],"decreased":[163],"but":[164],"within":[166],"range":[168],"control":[172],"subjects.":[173],"fibrinopeptide":[175],"A":[176],"generation":[177],"4":[179],"minutes":[180],"2600":[184],"s-1":[185],"higher":[187,201],".05)":[196],"associated":[198],"plasma":[202],"fibrinogen":[203],"level":[204],".005).":[207],"signs":[209],"changed":[211],"reactivity":[213],"flowing":[215],"only":[220],"they":[227],"smoked":[229],"cigarette.":[231]},"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
