{"id":"https://openalex.org/W2059006291","doi":"https://doi.org/10.1117/12.382719","title":"Calcium detection of human hair and nail by the nanosecond time-gated spectroscopy of laser-ablation plume","display_name":"Calcium detection of human hair and nail by the nanosecond time-gated spectroscopy of laser-ablation plume","publication_year":2000,"publication_date":"2000-04-19","ids":{"openalex":"https://openalex.org/W2059006291","doi":"https://doi.org/10.1117/12.382719","mag":"2059006291"},"language":"en","primary_location":{"id":"doi:10.1117/12.382719","doi":"https://doi.org/10.1117/12.382719","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.382719","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111798655","display_name":"Masamitsu Haruna","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masamitsu Haruna","raw_affiliation_strings":["Osaka Univ. School of Allied Health Sciences (Japan)","[Osaka University School of Allied Health Sciences, Japan]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Osaka Univ. School of Allied Health Sciences (Japan)","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"[Osaka University School of Allied Health Sciences, Japan]","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110536080","display_name":"Masato Ohmi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masato Ohmi","raw_affiliation_strings":["Osaka Univ. School of Allied Health Sciences (Japan)","[Osaka University School of Allied Health Sciences, Japan]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Osaka Univ. School of Allied Health Sciences (Japan)","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"[Osaka University School of Allied Health Sciences, Japan]","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104052679","display_name":"Mitsuo Nakamura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mitsuo Nakamura","raw_affiliation_strings":["Osaka Univ. School of Allied Health Sciences (Japan)","[Osaka University School of Allied Health Sciences, Japan]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Osaka Univ. School of Allied Health Sciences (Japan)","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"[Osaka University School of Allied Health Sciences, Japan]","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051183847","display_name":"Shigeto Morimoto","orcid":"https://orcid.org/0000-0002-8599-8257","observed_orcids":["https://orcid.org/0000-0002-8599-8257"]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shigeto Morimoto","raw_affiliation_strings":["Osaka Univ. Graduate School of Medicine (Japan)","Osaka University Graduate School of Medicine Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Osaka Univ. Graduate School of Medicine (Japan)","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"Osaka University Graduate School of Medicine Japan","institution_ids":["https://openalex.org/I98285908"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I98285908"],"apc_list":null,"apc_paid":null,"fwci":2.6718,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.85010267,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"3917","issue":null,"first_page":"87","last_page":"92"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11854","display_name":"Laser-induced spectroscopy and plasma","score":0.975600004196167,"subfield":{"id":"https://openalex.org/subfields/2211","display_name":"Mechanics of Materials"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11854","display_name":"Laser-induced spectroscopy and plasma","score":0.975600004196167,"subfield":{"id":"https://openalex.org/subfields/2211","display_name":"Mechanics of Materials"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13232","display_name":"Laser-Ablation Synthesis of Nanoparticles","score":0.010900000110268593,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.0044999998062849045,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/calcium-detection","display_name":"calcium detection","score":0.9760000109672546},{"id":"https://openalex.org/keywords/human-hair","display_name":"human hair","score":0.8140000104904175},{"id":"https://openalex.org/keywords/human-nails","display_name":"human nails","score":0.9340000152587891},{"id":"https://openalex.org/keywords/laser-ablation-plume","display_name":"laser ablation plume","score":0.8029999732971191},{"id":"https://openalex.org/keywords/optical-biopsy","display_name":"optical biopsy","score":0.6389999985694885},{"id":"https://openalex.org/keywords/ionized-carbon","display_name":"ionized carbon","score":0.8009999990463257},{"id":"https://openalex.org/keywords/osteoporosis-screening","display_name":"osteoporosis screening","score":0.7829999923706055}],"concepts":[{"id":"https://openalex.org/C2779188808","wikidata":"https://www.wikidata.org/wiki/Q1806547","display_name":"Laser ablation","level":3,"score":0.6950286626815796},{"id":"https://openalex.org/C32891209","wikidata":"https://www.wikidata.org/wiki/Q483666","display_name":"Spectroscopy","level":2,"score":0.6366428136825562},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6196715831756592},{"id":"https://openalex.org/C2778902805","wikidata":"https://www.wikidata.org/wiki/Q322177","display_name":"Ablation","level":2,"score":0.6080241203308105},{"id":"https://openalex.org/C148869448","wikidata":"https://www.wikidata.org/wiki/Q184240","display_name":"Luminescence","level":2,"score":0.5865862369537354},{"id":"https://openalex.org/C520434653","wikidata":"https://www.wikidata.org/wiki/Q38867","display_name":"Laser","level":2,"score":0.5778371095657349},{"id":"https://openalex.org/C51141536","wikidata":"https://www.wikidata.org/wiki/Q838801","display_name":"Nanosecond","level":3,"score":0.5374290347099304},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.4301597476005554},{"id":"https://openalex.org/C2775840915","wikidata":"https://www.wikidata.org/wiki/Q3817528","display_name":"Plume","level":2,"score":0.4254150092601776},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.40474823117256165},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.22670522332191467},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1422116458415985},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0814996063709259},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1117/12.382719","doi":"https://doi.org/10.1117/12.382719","is_oa":false,"landing_page_url":"https://doi.org/10.1117/12.382719","pdf_url":null,"source":{"id":"https://openalex.org/S183492911","display_name":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","issn_l":"0277-786X","issn":["0277-786X","1996-756X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SPIE Proceedings","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4000000059604645,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.46000000834465027,"display_name":"Affordable and clean energy","id":"https://metadata.un.org/sdg/7"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2080766278","https://openalex.org/W2298870865","https://openalex.org/W1940885666","https://openalex.org/W2147794715","https://openalex.org/W2081305085","https://openalex.org/W2560330190","https://openalex.org/W2896812212","https://openalex.org/W2052524705","https://openalex.org/W3143833596","https://openalex.org/W1965319168"],"abstract_inverted_index":{"We":[0],"demonstrate":[1],"the":[2,25,44,51,88,113],"nanosecond":[3],"time-gated":[4],"spectroscopy":[5,77],"of":[6,11,27,40,47,65,120,130,133,139],"plume":[7,49],"in":[8,43,58,112],"laser":[9,34,85],"ablation":[10],"biological":[12],"tissue,":[13],"which":[14],"allows":[15],"us":[16],"to":[17,125],"detect":[18],"calcium":[19],"(Ca)":[20],"with":[21],"high":[22],"sensitivity":[23],"by":[24],"use":[26],"either":[28],"a":[29,32,82,106,136],"UV":[30],"or":[31],"near-IR":[33],"pulse.":[35],"Clear":[36],"and":[37,61,69,91,135],"sharp":[38],"peaks":[39,64],"Ca+":[41],"appear":[42],"luminescence":[45],"spectrum":[46],"laser-ablation":[48],"although":[50],"Ca":[52,118,134],"content":[53],"is":[54,78,105],"only":[55],"0.1":[56],"percent":[57],"human":[59,121],"hair":[60,122],"nail.":[62],"Luminescence":[63],"sodium":[66],"atom":[67],"(Na)":[68],"ionized":[70],"carbon":[71],"are":[72],"also":[73],"detectable.":[74],"This":[75,102],"specific":[76],"low":[79],"invasive":[80],"because":[81],"single":[83],"low-energy":[84],"pulse":[86],"illuminates":[87],"tissue":[89],"sample,":[90],"it":[92],"does":[93],"not":[94],"require":[95],"any":[96],"poisonous":[97],"sensititizers":[98],"like":[99],"fluorescence":[100],"dye.":[101],"method,":[103],"therefore,":[104],"promising":[107],"candidate":[108],"for":[109],"optical":[110],"biopsy":[111],"near":[114],"future.":[115],"In":[116],"particular,":[117],"detection":[119],"may":[123],"lead":[124],"new":[126],"diagnosis,":[127],"including":[128],"monitor":[129],"daily":[131],"intake":[132],"screening":[137],"diagnosis":[138],"osteoporosis.":[140]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2025-10-10T00:00:00"}