{"id":"https://openalex.org/W2058840403","doi":"https://doi.org/10.5262/tndt.2010.1002.75","title":"Severe Pancytopenia Induced by Low-dose Methotrexate in a Hemodialysis Patient","display_name":"Severe Pancytopenia Induced by Low-dose Methotrexate in a Hemodialysis Patient","publication_year":2010,"publication_date":"2010-06-03","ids":{"openalex":"https://openalex.org/W2058840403","doi":"https://doi.org/10.5262/tndt.2010.1002.75","mag":"2058840403"},"language":"en","primary_location":{"id":"doi:10.5262/tndt.2010.1002.75","doi":"https://doi.org/10.5262/tndt.2010.1002.75","is_oa":false,"landing_page_url":"https://doi.org/10.5262/tndt.2010.1002.75","pdf_url":null,"source":{"id":"https://openalex.org/S4210227998","display_name":"Turkish Journal of Nephrology","issn_l":"1300-7718","issn":["1300-7718","2667-4440"],"is_oa":false,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-4","tr-dizin"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Turkish Nephrology Dialysis Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doaj.org/article/cc9f91626ff9447ca8ea702aeddf4b3b","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001324619","display_name":"\u0130rem Pembeg\u00fcl Yi\u011fit","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Irem Pembegul Yigit","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047730055","display_name":"Ramazan Ulu","orcid":"https://orcid.org/0000-0003-1461-2764","observed_orcids":["https://orcid.org/0000-0003-1461-2764"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ramazan Ulu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038573602","display_name":"Yener Yildiz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yener Yildiz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049641274","display_name":"Ayhan Do\u011fukan","orcid":"https://orcid.org/0000-0002-7111-7260","observed_orcids":["https://orcid.org/0000-0002-7111-7260","https://orcid.org/0009-0002-5268-2608"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ayhan Dogukan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5070188672","display_name":"H\u00fcseyin \u00c7eli\u0307ker","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Huseyin Celiker","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.18965855,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"19","issue":"2","first_page":"147","last_page":"149"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.44679999351501465,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.44679999351501465,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13374","display_name":"Hematological disorders and diagnostics","score":0.11079999804496765,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.08649999648332596,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/methotrexate","display_name":"methotrexate","score":0.9269999861717224},{"id":"https://openalex.org/keywords/pancytopenia","display_name":"pancytopenia","score":0.9729999899864197},{"id":"https://openalex.org/keywords/hemodialysis","display_name":"hemodialysis","score":0.8389999866485596},{"id":"https://openalex.org/keywords/low-dose-methotrexate","display_name":"low-dose methotrexate","score":0.8370000123977661},{"id":"https://openalex.org/keywords/stomatitis","display_name":"stomatitis","score":0.6000000238418579},{"id":"https://openalex.org/keywords/leucovorin","display_name":"leucovorin","score":0.8230000138282776},{"id":"https://openalex.org/keywords/granulocyte-colony-stimulating-factor","display_name":"granulocyte colony-stimulating factor","score":0.996999979019165},{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"rheumatoid arthritis","score":0.9440000057220459},{"id":"https://openalex.org/keywords/drug-induced-hematologic-toxicity","display_name":"drug-induced hematologic toxicity","score":0.6370000243186951}],"concepts":[{"id":"https://openalex.org/C2779382419","wikidata":"https://www.wikidata.org/wiki/Q1757427","display_name":"Pancytopenia","level":3,"score":0.9437988996505737},{"id":"https://openalex.org/C2778063415","wikidata":"https://www.wikidata.org/wiki/Q391744","display_name":"Hemodialysis","level":2,"score":0.7268809676170349},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6881446838378906},{"id":"https://openalex.org/C2781059491","wikidata":"https://www.wikidata.org/wiki/Q422232","display_name":"Methotrexate","level":2,"score":0.6629390120506287},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.395891398191452},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3212547302246094},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.16021841764450073}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.5262/tndt.2010.1002.75","doi":"https://doi.org/10.5262/tndt.2010.1002.75","is_oa":false,"landing_page_url":"https://doi.org/10.5262/tndt.2010.1002.75","pdf_url":null,"source":{"id":"https://openalex.org/S4210227998","display_name":"Turkish Journal of Nephrology","issn_l":"1300-7718","issn":["1300-7718","2667-4440"],"is_oa":false,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-4","tr-dizin"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Turkish Nephrology Dialysis Transplantation","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:cc9f91626ff9447ca8ea702aeddf4b3b","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/cc9f91626ff9447ca8ea702aeddf4b3b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Turkish Journal of Nephrology, Vol 19, Iss 2 (2019)","raw_type":"article"},{"id":"pmh:oai:openaccess.firat.edu.tr:11508/37832","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/11508/37832","pdf_url":null,"source":{"id":"https://openalex.org/S4377196733","display_name":"DSpace - FIRAT (F\u0131rat University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I143396566","host_organization_name":"F\u0131rat University","host_organization_lineage":["https://openalex.org/I143396566"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:openaccess.firat.edu.tr:11508/47614","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/11508/47614","pdf_url":null,"source":{"id":"https://openalex.org/S4377196733","display_name":"DSpace - FIRAT (F\u0131rat University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I143396566","host_organization_name":"F\u0131rat University","host_organization_lineage":["https://openalex.org/I143396566"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Editorial"}],"best_oa_location":{"id":"pmh:oai:doaj.org/article:cc9f91626ff9447ca8ea702aeddf4b3b","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/cc9f91626ff9447ca8ea702aeddf4b3b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Turkish Journal of Nephrology, Vol 19, Iss 2 (2019)","raw_type":"article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3203889476","https://openalex.org/W2097638515","https://openalex.org/W4225592341","https://openalex.org/W2023589406","https://openalex.org/W2400500188","https://openalex.org/W2411280618","https://openalex.org/W2261225520","https://openalex.org/W1987955143","https://openalex.org/W2186133703","https://openalex.org/W2110395758"],"abstract_inverted_index":{"Methotrexate":[0],"has":[1,29],"been":[2,30],"used":[3],"as":[4],"an":[5],"important":[6],"alternative":[7],"therapy":[8],"in":[9,26],"the":[10,21],"treatment":[11,45],"of":[12],"various":[13],"rheumatic":[14],"diseases.":[15],"It":[16],"is":[17],"primarily":[18],"cleared":[19],"by":[20],"kidney.":[22],"Life-threatening":[23],"marrow":[24],"suppression":[25],"hemodialysis":[27,36,60],"patients":[28],"reported.":[31],"A":[32],"35-year-old":[33],"woman":[34],"undergoing":[35],"developed":[37],"severe":[38],"stomatitis":[39],"and":[40,58],"pancytopenia":[41],"after":[42,51],"low-dose":[43],"methotrexate":[44],"for":[46],"rheumatoid":[47],"arthritis.":[48],"She":[49],"recovered":[50],"folinic":[52],"acid,":[53],"granulocyte":[54],"colony-stimulating":[55],"factor,":[56],"antibiotic":[57],"daily":[59],"therapy.":[61]},"counts_by_year":[{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}