{"id":"https://openalex.org/W2058349488","doi":"https://doi.org/10.1002/(sici)1098-1063(1998)8:4<313::aid-hipo1>3.0.co;2-i","title":"Hippocampal PET activations of memory encoding and retrieval: The HIPER model","display_name":"Hippocampal PET activations of memory encoding and retrieval: The HIPER model","publication_year":1998,"publication_date":"1998-01-01","ids":{"openalex":"https://openalex.org/W2058349488","doi":"https://doi.org/10.1002/(sici)1098-1063(1998)8:4<313::aid-hipo1>3.0.co;2-i","mag":"2058349488","pmid":"https://pubmed.ncbi.nlm.nih.gov/9744418"},"language":"en","primary_location":{"id":"doi:10.1002/(sici)1098-1063(1998)8:4<313::aid-hipo1>3.0.co;2-i","doi":"https://doi.org/10.1002/(sici)1098-1063(1998)8:4<313::aid-hipo1>3.0.co;2-i","is_oa":false,"landing_page_url":"https://doi.org/10.1002/(sici)1098-1063(1998)8:4<313::aid-hipo1>3.0.co;2-i","pdf_url":null,"source":{"id":"https://openalex.org/S55111660","display_name":"Hippocampus","issn_l":"1050-9631","issn":["1050-9631","1098-1063"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hippocampus","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036883041","display_name":"Mart\u00edn Lepage","orcid":"https://orcid.org/0000-0003-4345-6502","observed_orcids":["https://orcid.org/0000-0003-4345-6502"]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I4405263474","display_name":"Rotman Research Institute","ror":"https://ror.org/01kvpec59","country_code":"CA","type":"education","lineage":["https://openalex.org/I4405258058","https://openalex.org/I4405263474"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Martin Lepage","raw_affiliation_strings":["Rotman Research Institute of Baycrest Centre, University of Toronto, Ontario, Canada. mlepage@rotman-baycrest.on.ca","Rotman Research Institute of Baycrest Centre, University of Toronto, Toronto, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rotman Research Institute of Baycrest Centre, University of Toronto, Ontario, Canada. mlepage@rotman-baycrest.on.ca","institution_ids":["https://openalex.org/I185261750","https://openalex.org/I4405263474"]},{"raw_affiliation_string":"Rotman Research Institute of Baycrest Centre, University of Toronto, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I185261750","https://openalex.org/I4405263474"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110085621","display_name":"Reza Habib","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I4405263474","display_name":"Rotman Research Institute","ror":"https://ror.org/01kvpec59","country_code":"CA","type":"education","lineage":["https://openalex.org/I4405258058","https://openalex.org/I4405263474"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Reza Habib","raw_affiliation_strings":["Rotman Research Institute of Baycrest Centre, University of Toronto, Toronto, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rotman Research Institute of Baycrest Centre, University of Toronto, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I185261750","https://openalex.org/I4405263474"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084881685","display_name":"Endel Tulving","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I4405263474","display_name":"Rotman Research Institute","ror":"https://ror.org/01kvpec59","country_code":"CA","type":"education","lineage":["https://openalex.org/I4405258058","https://openalex.org/I4405263474"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Endel Tulving","raw_affiliation_strings":["Rotman Research Institute of Baycrest Centre, University of Toronto, Toronto, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rotman Research Institute of Baycrest Centre, University of Toronto, Toronto, Ontario, Canada","institution_ids":["https://openalex.org/I185261750","https://openalex.org/I4405263474"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5036883041"],"corresponding_institution_ids":["https://openalex.org/I185261750","https://openalex.org/I4405263474"],"apc_list":{"value":4780,"currency":"USD","value_usd":4780},"apc_paid":null,"fwci":17.644,"has_fulltext":false,"cited_by_count":512,"citation_normalized_percentile":{"value":0.99684202,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"8","issue":"4","first_page":"313","last_page":"322"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.6352999806404114,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.6352999806404114,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10918","display_name":"Memory Processes and Influences","score":0.3621000051498413,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13471","display_name":"Cognitive Functions and Memory","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/episodic-memory","display_name":"episodic memory","score":0.8299999833106995},{"id":"https://openalex.org/keywords/memory-encoding","display_name":"memory encoding","score":0.9980000257492065},{"id":"https://openalex.org/keywords/memory-retrieval","display_name":"memory retrieval","score":1.0},{"id":"https://openalex.org/keywords/rostrocaudal-gradient","display_name":"rostrocaudal gradient","score":0.9210000038146973},{"id":"https://openalex.org/keywords/functional-neuroanatomy","display_name":"functional neuroanatomy","score":0.7490000128746033},{"id":"https://openalex.org/keywords/hippocampal-formation","display_name":"hippocampal formation","score":0.7160000205039978}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7201228737831116},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.6922755837440491},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.5144786834716797},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.49512186646461487},{"id":"https://openalex.org/C88576662","wikidata":"https://www.wikidata.org/wiki/Q18646","display_name":"Episodic memory","level":3,"score":0.43058478832244873},{"id":"https://openalex.org/C125411270","wikidata":"https://www.wikidata.org/wiki/Q18653","display_name":"Encoding (memory)","level":2,"score":0.41464585065841675},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.36688876152038574},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.2544183135032654}],"mesh":[{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008568","descriptor_name":"Memory","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014055","descriptor_name":"Tomography, Emission-Computed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1002/(sici)1098-1063(1998)8:4<313::aid-hipo1>3.0.co;2-i","doi":"https://doi.org/10.1002/(sici)1098-1063(1998)8:4<313::aid-hipo1>3.0.co;2-i","is_oa":false,"landing_page_url":"https://doi.org/10.1002/(sici)1098-1063(1998)8:4<313::aid-hipo1>3.0.co;2-i","pdf_url":null,"source":{"id":"https://openalex.org/S55111660","display_name":"Hippocampus","issn_l":"1050-9631","issn":["1050-9631","1098-1063"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hippocampus","raw_type":"journal-article"},{"id":"pmid:9744418","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9744418","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hippocampus","raw_type":"Journal Article"},{"id":"mag:2290051147","doi":null,"is_oa":false,"landing_page_url":"http://alicekim.ca/Hiper.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"},{"id":"https://openalex.org/study-designs/meta-analysis","display_name":"Meta-Analysis"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320334593","display_name":"Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":95,"referenced_works":["https://openalex.org/W94353036","https://openalex.org/W1482184480","https://openalex.org/W1655746131","https://openalex.org/W1897270614","https://openalex.org/W1920237903","https://openalex.org/W1948611034","https://openalex.org/W1965769566","https://openalex.org/W1967306597","https://openalex.org/W1967695170","https://openalex.org/W1967789445","https://openalex.org/W1968575533","https://openalex.org/W1969794982","https://openalex.org/W1970690517","https://openalex.org/W1973063801","https://openalex.org/W1975054882","https://openalex.org/W1975898250","https://openalex.org/W1977031758","https://openalex.org/W1977676214","https://openalex.org/W1979162498","https://openalex.org/W1981665989","https://openalex.org/W1984214648","https://openalex.org/W1984447553","https://openalex.org/W1986004048","https://openalex.org/W1989345183","https://openalex.org/W1993521400","https://openalex.org/W1994218412","https://openalex.org/W1994364033","https://openalex.org/W1997643541","https://openalex.org/W1999400626","https://openalex.org/W2002110998","https://openalex.org/W2002353920","https://openalex.org/W2006409313","https://openalex.org/W2007126717","https://openalex.org/W2007131990","https://openalex.org/W2009268248","https://openalex.org/W2017444226","https://openalex.org/W2028675229","https://openalex.org/W2038749059","https://openalex.org/W2042014574","https://openalex.org/W2043428207","https://openalex.org/W2045032692","https://openalex.org/W2046030161","https://openalex.org/W2053790038","https://openalex.org/W2057657513","https://openalex.org/W2058113871","https://openalex.org/W2061058047","https://openalex.org/W2063237661","https://openalex.org/W2064087276","https://openalex.org/W2065360467","https://openalex.org/W2070217033","https://openalex.org/W2076223112","https://openalex.org/W2076828848","https://openalex.org/W2077771942","https://openalex.org/W2079035297","https://openalex.org/W2080967129","https://openalex.org/W2082733505","https://openalex.org/W2083492091","https://openalex.org/W2088047654","https://openalex.org/W2088326990","https://openalex.org/W2088640426","https://openalex.org/W2089194320","https://openalex.org/W2090523362","https://openalex.org/W2091867117","https://openalex.org/W2092764200","https://openalex.org/W2092849013","https://openalex.org/W2095416572","https://openalex.org/W2095422075","https://openalex.org/W2096034317","https://openalex.org/W2097065530","https://openalex.org/W2097867833","https://openalex.org/W2098154433","https://openalex.org/W2100224172","https://openalex.org/W2104583974","https://openalex.org/W2106138734","https://openalex.org/W2106235350","https://openalex.org/W2115667067","https://openalex.org/W2116649573","https://openalex.org/W2120940453","https://openalex.org/W2121169817","https://openalex.org/W2123155553","https://openalex.org/W2128351720","https://openalex.org/W2130410346","https://openalex.org/W2136100138","https://openalex.org/W2137507212","https://openalex.org/W2138035300","https://openalex.org/W2139228910","https://openalex.org/W2140359075","https://openalex.org/W2145076416","https://openalex.org/W2145129394","https://openalex.org/W2150164835","https://openalex.org/W2154852695","https://openalex.org/W2159404024","https://openalex.org/W2169428430","https://openalex.org/W2170515927","https://openalex.org/W3127623214"],"related_works":["https://openalex.org/W2290051147","https://openalex.org/W7097449891","https://openalex.org/W2110221126","https://openalex.org/W2189577130","https://openalex.org/W2015498681","https://openalex.org/W2002353920","https://openalex.org/W1935688460","https://openalex.org/W4401646286","https://openalex.org/W2009533827","https://openalex.org/W1986004048"],"abstract_inverted_index":{"A":[0],"meta-analysis":[1],"of":[2,16,42,66,69,84,89,97,100,117,126,134,165,188],"experimentally":[3],"induced":[4],"changes":[5],"in":[6,10,26,38,55,168],"blood":[7],"flow":[8],"(\"activations\")":[9],"positron":[11],"emission":[12],"tomography":[13],"(PET)":[14],"studies":[15,88],"memory":[17,33,50,167],"has":[18],"revealed":[19],"an":[20,64,80],"orderly":[21],"functional":[22,131,163],"anatomic":[23,132],"pattern:":[24],"Activations":[25],"the":[27,39,43,56,107,121,127,141,153,169,185],"hippocampal":[28,128,170],"region":[29],"associated":[30,47],"with":[31,48],"episodic":[32,49,166],"encoding":[34,72,101,135],"are":[35,52,61],"located":[36,53],"primarily":[37,54,176],"rostral":[40,122],"portions":[41,125],"region,":[44],"whereas":[45],"activations":[46,75,105],"retrieval":[51,103,137],"caudal":[57,124],"portions.":[58],"These":[59],"findings":[60],"based":[62],"on":[63],"analysis":[65],"a":[67,115],"sample":[68],"54":[70],"\"hippocampal":[71],"and":[73,102,123,136,146],"retrieval\"":[74],"that":[76,139],"were":[77],"culled":[78],"from":[79],"overall":[81],"database":[82],"consisting":[83],"52":[85],"published":[86],"PET":[87,104],"memory.":[90,190],"We":[91],"refer":[92],"to":[93,151,155],"this":[94],"general":[95],"pattern":[96,133],"rostrocaudal":[98],"gradient":[99],"as":[106],"HIPER":[108,142],"(Hippocampal":[109],"Encoding/Retrieval)":[110],"model.":[111],"The":[112,172],"model":[113,143,154,173],"suggests":[114],"division":[116],"memory-related":[118],"labor":[119],"between":[120],"formation.":[129],"Because":[130],"activation":[138],"defines":[140],"was":[144],"unprecedented":[145],"unexpected,":[147],"it":[148],"is":[149,157,174],"difficult":[150],"relate":[152],"what":[156],"already":[158],"known":[159],"or":[160],"thought":[161],"about":[162],"neuroanatomy":[164],"regions.":[171],"interesting":[175],"because":[177],"its":[178],"exploration":[179],"may":[180],"yield":[181],"fresh":[182],"insights":[183],"into":[184],"neural":[186],"basis":[187],"human":[189]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":17},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":15},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":17},{"year":2014,"cited_by_count":18},{"year":2013,"cited_by_count":17},{"year":2012,"cited_by_count":31}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}