{"id":"https://openalex.org/W2058044669","doi":"https://doi.org/10.1006/smvy.1994.1041","title":"The E5 transforming proteins of the papillomaviruses","display_name":"The E5 transforming proteins of the papillomaviruses","publication_year":1994,"publication_date":"1994-10-01","ids":{"openalex":"https://openalex.org/W2058044669","doi":"https://doi.org/10.1006/smvy.1994.1041","mag":"2058044669"},"language":"en","primary_location":{"id":"doi:10.1006/smvy.1994.1041","doi":"https://doi.org/10.1006/smvy.1994.1041","is_oa":true,"landing_page_url":"https://doi.org/10.1006/smvy.1994.1041","pdf_url":null,"source":{"id":"https://openalex.org/S3711100","display_name":"Seminars in Virology","issn_l":"1044-5773","issn":["1044-5773","1098-1292"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319955","host_organization_name":"Academic Press","host_organization_lineage":["https://openalex.org/P4310319955","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Academic Press","Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in Virology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1006/smvy.1994.1041","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028430067","display_name":"Daniel DiMaio","orcid":"https://orcid.org/0000-0002-2060-5977","observed_orcids":["https://orcid.org/0000-0002-2060-5977"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel DiMaio","raw_affiliation_strings":["Department of Genetics, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018752104","display_name":"Lisa M. Petti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lisa Petti","raw_affiliation_strings":["Department of Genetics, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070572030","display_name":"Eun-Seong Hwang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eun-Seong Hwang","raw_affiliation_strings":["Department of Genetics, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA","institution_ids":["https://openalex.org/I32971472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I32971472"],"apc_list":null,"apc_paid":null,"fwci":2.0561,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.85825512,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"5","issue":"5","first_page":"369","last_page":"379"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bovine-papillomavirus","display_name":"bovine papillomavirus","score":0.8659999966621399},{"id":"https://openalex.org/keywords/human-papillomavirus","display_name":"human papillomavirus","score":0.8790000081062317},{"id":"https://openalex.org/keywords/viral-carcinogenesis","display_name":"viral oncogenesis","score":0.5720000267028809},{"id":"https://openalex.org/keywords/pdgf-receptor-beta","display_name":"PDGF receptor beta","score":0.7799999713897705},{"id":"https://openalex.org/keywords/egf-receptor","display_name":"EGF receptor","score":0.9359999895095825},{"id":"https://openalex.org/keywords/vacuolar-h-atpase","display_name":"vacuolar H+-ATPase","score":0.9769999980926514},{"id":"https://openalex.org/keywords/alpha-adaptin","display_name":"alpha-adaptin","score":0.9819999933242798},{"id":"https://openalex.org/keywords/protein-protein-interaction","display_name":"protein-protein interaction","score":0.7480000257492065},{"id":"https://openalex.org/keywords/fibroblast-transformation","display_name":"fibroblast transformation","score":0.8109999895095825},{"id":"https://openalex.org/keywords/keratinocytes","display_name":"keratinocytes","score":0.9549999833106995}],"concepts":[{"id":"https://openalex.org/C2776781592","wikidata":"https://www.wikidata.org/wiki/Q4950565","display_name":"Bovine papillomavirus","level":4,"score":0.7936821579933167},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.640643298625946},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5404804944992065},{"id":"https://openalex.org/C104292427","wikidata":"https://www.wikidata.org/wiki/Q899781","display_name":"Protein subunit","level":3,"score":0.5087445378303528},{"id":"https://openalex.org/C163181125","wikidata":"https://www.wikidata.org/wiki/Q408592","display_name":"GTPase-activating protein","level":4,"score":0.4979698657989502},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.43457236886024475},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.3104579448699951},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2797399163246155},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2559632658958435},{"id":"https://openalex.org/C80631254","wikidata":"https://www.wikidata.org/wiki/Q407438","display_name":"G protein","level":3,"score":0.24753275513648987},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.08376511931419373}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1006/smvy.1994.1041","doi":"https://doi.org/10.1006/smvy.1994.1041","is_oa":true,"landing_page_url":"https://doi.org/10.1006/smvy.1994.1041","pdf_url":null,"source":{"id":"https://openalex.org/S3711100","display_name":"Seminars in Virology","issn_l":"1044-5773","issn":["1044-5773","1098-1292"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319955","host_organization_name":"Academic Press","host_organization_lineage":["https://openalex.org/P4310319955","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Academic Press","Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in Virology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1006/smvy.1994.1041","doi":"https://doi.org/10.1006/smvy.1994.1041","is_oa":true,"landing_page_url":"https://doi.org/10.1006/smvy.1994.1041","pdf_url":null,"source":{"id":"https://openalex.org/S3711100","display_name":"Seminars in Virology","issn_l":"1044-5773","issn":["1044-5773","1098-1292"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319955","host_organization_name":"Academic Press","host_organization_lineage":["https://openalex.org/P4310319955","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Academic Press","Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in Virology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.504800021648407}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1874875782","https://openalex.org/W2032310661","https://openalex.org/W2051571555","https://openalex.org/W1796832639","https://openalex.org/W2097716740","https://openalex.org/W1251519535","https://openalex.org/W2164133334","https://openalex.org/W1835663015","https://openalex.org/W2085652591","https://openalex.org/W2127601115"],"abstract_inverted_index":{"The":[0,14,81],"E5":[1,18,53,63,82],"proteins":[2,7,84],"are":[3],"short,":[4],"hydrophobic":[5],"transforming":[6,48,83],"encoded":[8],"by":[9],"many":[10],"of":[11,20,32,46,50,60,71,85],"the":[12,38,47,51,61,66,72,86],"papillomaviruses.":[13],"44":[15],"amino":[16],"acid":[17],"protein":[19,54,64,77],"bovine":[21],"papillomavirus":[22],"efficiently":[23],"transforms":[24],"cultured":[25],"fibroblasts":[26],"and":[27,75],"interacts":[28],"with":[29,91],"a":[30,69,76],"variety":[31],"cellular":[33,93],"proteins,":[34],"Considerable":[35],"evidence":[36],"implicates":[37],"PDGF":[39],"\u03b2":[40],"receptor":[41],"as":[42],"an":[43],"important":[44],"mediator":[45],"activity":[49],"BPV":[52,62],"in":[55,95],"fibroblasts.":[56],"Other":[57],"potential":[58],"targets":[59,94],"include":[65],"EGF":[67],"receptor,":[68],"subunit":[70],"vacuolar":[73],"H+-ATPase,":[74],"related":[78],"to":[79],"\u03b1-adaptin.":[80],"human":[87],"papillomaviruses":[88],"may":[89],"interact":[90],"similar":[92],"keratinocytes.":[96]},"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}