{"id":"https://openalex.org/W2056976674","doi":"https://doi.org/10.1006/jmbi.1996.0293","title":"Structure and Orientation of the Mammalian Antibacterial Peptide Cecropin P1 within Phospholipid Membranes","display_name":"Structure and Orientation of the Mammalian Antibacterial Peptide Cecropin P1 within Phospholipid Membranes","publication_year":1996,"publication_date":"1996-05-01","ids":{"openalex":"https://openalex.org/W2056976674","doi":"https://doi.org/10.1006/jmbi.1996.0293","mag":"2056976674","pmid":"https://pubmed.ncbi.nlm.nih.gov/8637016"},"language":"en","primary_location":{"id":"doi:10.1006/jmbi.1996.0293","doi":"https://doi.org/10.1006/jmbi.1996.0293","is_oa":false,"landing_page_url":"https://doi.org/10.1006/jmbi.1996.0293","pdf_url":null,"source":{"id":"https://openalex.org/S46058472","display_name":"Journal of Molecular Biology","issn_l":"0022-2836","issn":["0022-2836","1089-8638"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular Biology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2056976674"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082716768","display_name":"Ehud Gazit","orcid":"https://orcid.org/0000-0001-5764-1720","observed_orcids":["https://orcid.org/0000-0001-5764-1720"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["GB","IL"],"is_corresponding":false,"raw_author_name":"Ehud Gazit","raw_affiliation_strings":["Department of Membrane Research and Biophysics, Weizmann Institute of Science, Rehovot, Israel","Department of Membrane Research and Biophysics, Weizmann Institute of Science, Rehovot 76100, Israel","Laboratory of Molecular Biophysics, University of Oxford, The Rex Richards Building, South Parks Road, Oxford, OX1 3QU, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Membrane Research and Biophysics, Weizmann Institute of Science, Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]},{"raw_affiliation_string":"Department of Membrane Research and Biophysics, Weizmann Institute of Science, Rehovot 76100, Israel","institution_ids":["https://openalex.org/I53964585"]},{"raw_affiliation_string":"Laboratory of Molecular Biophysics, University of Oxford, The Rex Richards Building, South Parks Road, Oxford, OX1 3QU, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113560291","display_name":"Israel R. Miller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["GB","IL"],"is_corresponding":false,"raw_author_name":"Israel R. Miller","raw_affiliation_strings":["Department of Membrane Research and Biophysics, Weizmann Institute of Science, Rehovot 76100, Israel","Laboratory of Molecular Biophysics, University of Oxford, The Rex Richards Building, South Parks Road, Oxford, OX1 3QU, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Membrane Research and Biophysics, Weizmann Institute of Science, Rehovot 76100, Israel","institution_ids":["https://openalex.org/I53964585"]},{"raw_affiliation_string":"Laboratory of Molecular Biophysics, University of Oxford, The Rex Richards Building, South Parks Road, Oxford, OX1 3QU, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034236085","display_name":"Philip Charles Biggin","orcid":"https://orcid.org/0000-0001-5100-8836","observed_orcids":["https://orcid.org/0000-0001-5100-8836"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["GB","IL"],"is_corresponding":false,"raw_author_name":"Phil C. Biggin","raw_affiliation_strings":["Department of Membrane Research and Biophysics, Weizmann Institute of Science, Rehovot 76100, Israel","Laboratory of Molecular Biophysics, University of Oxford, The Rex Richards Building, South Parks Road, Oxford, OX1 3QU, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Membrane Research and Biophysics, Weizmann Institute of Science, Rehovot 76100, Israel","institution_ids":["https://openalex.org/I53964585"]},{"raw_affiliation_string":"Laboratory of Molecular Biophysics, University of Oxford, The Rex Richards Building, South Parks Road, Oxford, OX1 3QU, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041718990","display_name":"Mark S.P. Sansom","orcid":"https://orcid.org/0000-0001-6360-7959","observed_orcids":["https://orcid.org/0000-0001-6360-7959"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["GB","IL"],"is_corresponding":false,"raw_author_name":"Mark S.P. Sansom","raw_affiliation_strings":["Department of Membrane Research and Biophysics, Weizmann Institute of Science, Rehovot 76100, Israel","Laboratory of Molecular Biophysics, University of Oxford, The Rex Richards Building, South Parks Road, Oxford, OX1 3QU, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Membrane Research and Biophysics, Weizmann Institute of Science, Rehovot 76100, Israel","institution_ids":["https://openalex.org/I53964585"]},{"raw_affiliation_string":"Laboratory of Molecular Biophysics, University of Oxford, The Rex Richards Building, South Parks Road, Oxford, OX1 3QU, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108605427","display_name":"Yechiel Shai","orcid":"https://orcid.org/0000-0002-8588-5586","observed_orcids":["https://orcid.org/0000-0002-8588-5586"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["GB","IL"],"is_corresponding":false,"raw_author_name":"Yechiel Shai","raw_affiliation_strings":["Department of Membrane Research and Biophysics, Weizmann Institute of Science, Rehovot 76100, Israel","Laboratory of Molecular Biophysics, University of Oxford, The Rex Richards Building, South Parks Road, Oxford, OX1 3QU, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Membrane Research and Biophysics, Weizmann Institute of Science, Rehovot 76100, Israel","institution_ids":["https://openalex.org/I53964585"]},{"raw_affiliation_string":"Laboratory of Molecular Biophysics, University of Oxford, The Rex Richards Building, South Parks Road, Oxford, OX1 3QU, UK","institution_ids":["https://openalex.org/I40120149"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4730,"currency":"USD","value_usd":4730},"apc_paid":null,"fwci":10.3394,"has_fulltext":false,"cited_by_count":290,"citation_normalized_percentile":{"value":0.99265183,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"258","issue":"5","first_page":"860","last_page":"870"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11103","display_name":"Antimicrobial Peptides and Activities","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11103","display_name":"Antimicrobial Peptides and Activities","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12526","display_name":"Antimicrobial agents and applications","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cecropin-p1","display_name":"cecropin P1","score":0.9940000176429749},{"id":"https://openalex.org/keywords/antibacterial-peptides","display_name":"antibacterial peptides","score":0.9399999976158142},{"id":"https://openalex.org/keywords/peptide-secondary-structure","display_name":"peptide secondary structure","score":0.8169999718666077},{"id":"https://openalex.org/keywords/peptide-orientation-in-membranes","display_name":"peptide orientation in membranes","score":0.8029999732971191},{"id":"https://openalex.org/keywords/alpha-helix","display_name":"alpha-helix","score":0.6549999713897705},{"id":"https://openalex.org/keywords/phosphatidylcholine","display_name":"phosphatidylcholine","score":0.9079999923706055},{"id":"https://openalex.org/keywords/carpet-mechanism","display_name":"carpet mechanism","score":0.7419999837875366},{"id":"https://openalex.org/keywords/membrane-potential","display_name":"membrane potential","score":0.8650000095367432},{"id":"https://openalex.org/keywords/molecular-dynamics-simulation","display_name":"molecular dynamics simulation","score":0.5270000100135803},{"id":"https://openalex.org/keywords/membrane-perturbation","display_name":"membrane perturbation","score":0.75}],"concepts":[{"id":"https://openalex.org/C2777366737","wikidata":"https://www.wikidata.org/wiki/Q24784723","display_name":"Cecropin","level":4,"score":0.7670813798904419},{"id":"https://openalex.org/C2778918659","wikidata":"https://www.wikidata.org/wiki/Q186915","display_name":"Phospholipid","level":3,"score":0.738612174987793},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.6695271134376526},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.6176574230194092},{"id":"https://openalex.org/C2993778972","wikidata":"https://www.wikidata.org/wiki/Q1201508","display_name":"Antibacterial peptide","level":4,"score":0.518763542175293},{"id":"https://openalex.org/C16345878","wikidata":"https://www.wikidata.org/wiki/Q107472979","display_name":"Orientation (vector space)","level":2,"score":0.4965530037879944},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.43987518548965454},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.36745691299438477},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.32258060574531555},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.25578492879867554},{"id":"https://openalex.org/C540938839","wikidata":"https://www.wikidata.org/wiki/Q1201508","display_name":"Antimicrobial peptides","level":3,"score":0.24072125554084778},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.21784716844558716},{"id":"https://openalex.org/C2780104969","wikidata":"https://www.wikidata.org/wiki/Q4774530","display_name":"Antibacterial activity","level":3,"score":0.1944420337677002},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.048004329204559326},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008051","descriptor_name":"Lipid Bilayers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008563","descriptor_name":"Membrane Lipids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010743","descriptor_name":"Phospholipids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017433","descriptor_name":"Protein Structure, Secondary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017550","descriptor_name":"Spectroscopy, Fourier Transform Infrared","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1006/jmbi.1996.0293","doi":"https://doi.org/10.1006/jmbi.1996.0293","is_oa":false,"landing_page_url":"https://doi.org/10.1006/jmbi.1996.0293","pdf_url":null,"source":{"id":"https://openalex.org/S46058472","display_name":"Journal of Molecular Biology","issn_l":"0022-2836","issn":["0022-2836","1089-8638"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular Biology","raw_type":"journal-article"},{"id":"pmid:8637016","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8637016","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of molecular biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2001784720","https://openalex.org/W2170109952","https://openalex.org/W2065927326","https://openalex.org/W2266832985","https://openalex.org/W1996213758","https://openalex.org/W1972096102","https://openalex.org/W1985218385","https://openalex.org/W1984591769","https://openalex.org/W2336308008","https://openalex.org/W56583029"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":12},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":17},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":12},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":19},{"year":2015,"cited_by_count":10},{"year":2014,"cited_by_count":14},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":14}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}