{"id":"https://openalex.org/W2056909801","doi":"https://doi.org/10.1021/ac800813a","title":"Assembly\u2212Disassembly of DNAs and Gold Nanoparticles: A Strategy of Intervention Based on Oligonucleotides and Restriction Enzymes","display_name":"Assembly\u2212Disassembly of DNAs and Gold Nanoparticles: A Strategy of Intervention Based on Oligonucleotides and Restriction Enzymes","publication_year":2008,"publication_date":"2008-07-09","ids":{"openalex":"https://openalex.org/W2056909801","doi":"https://doi.org/10.1021/ac800813a","mag":"2056909801","pmid":"https://pubmed.ncbi.nlm.nih.gov/18613651"},"language":"en","primary_location":{"id":"doi:10.1021/ac800813a","doi":"https://doi.org/10.1021/ac800813a","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ac800813a","pdf_url":null,"source":{"id":"https://openalex.org/S191963794","display_name":"Analytical Chemistry","issn_l":"0003-2700","issn":["0003-2700","1520-6882"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110038516","display_name":"I-Im S. Lim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I123946342","display_name":"Binghamton University","ror":"https://ror.org/008rmbt77","country_code":"US","type":"education","lineage":["https://openalex.org/I123946342"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"I-Im S. Lim","raw_affiliation_strings":["Departments of Chemistry, and Department of Biological Sciences, State University of New York at Binghamton, Binghamton, New York 13902"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Chemistry, and Department of Biological Sciences, State University of New York at Binghamton, Binghamton, New York 13902","institution_ids":["https://openalex.org/I123946342"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024787167","display_name":"Uma Chandrachud","orcid":"https://orcid.org/0000-0002-7848-1102","observed_orcids":["https://orcid.org/0000-0002-7848-1102"]},"institutions":[{"id":"https://openalex.org/I123946342","display_name":"Binghamton University","ror":"https://ror.org/008rmbt77","country_code":"US","type":"education","lineage":["https://openalex.org/I123946342"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Uma Chandrachud","raw_affiliation_strings":["Departments of Chemistry, and Department of Biological Sciences, State University of New York at Binghamton, Binghamton, New York 13902"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Chemistry, and Department of Biological Sciences, State University of New York at Binghamton, Binghamton, New York 13902","institution_ids":["https://openalex.org/I123946342"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100625938","display_name":"Lingyan Wang","orcid":"https://orcid.org/0000-0002-7640-8577","observed_orcids":["https://orcid.org/0000-0002-7640-8577"]},"institutions":[{"id":"https://openalex.org/I123946342","display_name":"Binghamton University","ror":"https://ror.org/008rmbt77","country_code":"US","type":"education","lineage":["https://openalex.org/I123946342"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lingyan Wang","raw_affiliation_strings":["Departments of Chemistry, and Department of Biological Sciences, State University of New York at Binghamton, Binghamton, New York 13902"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Chemistry, and Department of Biological Sciences, State University of New York at Binghamton, Binghamton, New York 13902","institution_ids":["https://openalex.org/I123946342"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024756657","display_name":"Susannah Gal","orcid":"https://orcid.org/0000-0001-5422-7807","observed_orcids":["https://orcid.org/0000-0001-5422-7807"]},"institutions":[{"id":"https://openalex.org/I123946342","display_name":"Binghamton University","ror":"https://ror.org/008rmbt77","country_code":"US","type":"education","lineage":["https://openalex.org/I123946342"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Susannah Gal","raw_affiliation_strings":["Departments of Chemistry, and Department of Biological Sciences, State University of New York at Binghamton, Binghamton, New York 13902"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Chemistry, and Department of Biological Sciences, State University of New York at Binghamton, Binghamton, New York 13902","institution_ids":["https://openalex.org/I123946342"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026877218","display_name":"Chuan\u2010Jian Zhong","orcid":"https://orcid.org/0000-0003-0746-250X","observed_orcids":["https://orcid.org/0000-0003-0746-250X"]},"institutions":[{"id":"https://openalex.org/I123946342","display_name":"Binghamton University","ror":"https://ror.org/008rmbt77","country_code":"US","type":"education","lineage":["https://openalex.org/I123946342"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Chuan-Jian Zhong","raw_affiliation_strings":["Departments of Chemistry, and Department of Biological Sciences, State University of New York at Binghamton, Binghamton, New York 13902"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Chemistry, and Department of Biological Sciences, State University of New York at Binghamton, Binghamton, New York 13902","institution_ids":["https://openalex.org/I123946342"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5024756657","https://openalex.org/A5026877218"],"corresponding_institution_ids":["https://openalex.org/I123946342"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":2.0551,"has_fulltext":false,"cited_by_count":35,"citation_normalized_percentile":{"value":0.8611638,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"80","issue":"15","first_page":"6038","last_page":"6044"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.8467000126838684,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.8467000126838684,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10131","display_name":"Gold and Silver Nanoparticles Synthesis and Applications","score":0.15139999985694885,"subfield":{"id":"https://openalex.org/subfields/2504","display_name":"Electronic, Optical and Magnetic Materials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oligonucleotides","display_name":"oligonucleotides","score":0.7850000262260437},{"id":"https://openalex.org/keywords/restriction-enzymes","display_name":"restriction enzymes","score":0.9900000095367432},{"id":"https://openalex.org/keywords/mspi","display_name":"MspI","score":0.9589999914169312},{"id":"https://openalex.org/keywords/dna-based-biosensors","display_name":"DNA-based biosensors","score":0.6919999718666077},{"id":"https://openalex.org/keywords/interfacial-reactivity","display_name":"interfacial reactivity","score":0.8690000176429749}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9553176760673523},{"id":"https://openalex.org/C129312508","wikidata":"https://www.wikidata.org/wiki/Q133686","display_name":"Oligonucleotide","level":3,"score":0.7870679497718811},{"id":"https://openalex.org/C104819515","wikidata":"https://www.wikidata.org/wiki/Q900961","display_name":"Colloidal gold","level":3,"score":0.7671199440956116},{"id":"https://openalex.org/C128319531","wikidata":"https://www.wikidata.org/wiki/Q219715","display_name":"Restriction enzyme","level":3,"score":0.5861395597457886},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.5636146068572998},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.5407533645629883},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.44772791862487793},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.4370030462741852},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.35193854570388794},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.34022611379623413},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.3233974575996399},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D004262","descriptor_name":"DNA Restriction Enzymes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006046","descriptor_name":"Gold","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009841","descriptor_name":"Oligonucleotides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053768","descriptor_name":"Metal Nanoparticles","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1021/ac800813a","doi":"https://doi.org/10.1021/ac800813a","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ac800813a","pdf_url":null,"source":{"id":"https://openalex.org/S191963794","display_name":"Analytical Chemistry","issn_l":"0003-2700","issn":["0003-2700","1520-6882"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical Chemistry","raw_type":"journal-article"},{"id":"pmid:18613651","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18613651","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical chemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W1492566521","https://openalex.org/W1494923926","https://openalex.org/W1598414788","https://openalex.org/W1658532712","https://openalex.org/W1968567751","https://openalex.org/W1970592466","https://openalex.org/W1975354299","https://openalex.org/W1977125458","https://openalex.org/W1979232921","https://openalex.org/W1979437243","https://openalex.org/W1985941691","https://openalex.org/W1989483493","https://openalex.org/W2003861548","https://openalex.org/W2012182308","https://openalex.org/W2017479359","https://openalex.org/W2022121414","https://openalex.org/W2025201292","https://openalex.org/W2025886916","https://openalex.org/W2027473433","https://openalex.org/W2042551540","https://openalex.org/W2043381968","https://openalex.org/W2048413555","https://openalex.org/W2048922080","https://openalex.org/W2052566608","https://openalex.org/W2059188511","https://openalex.org/W2061755273","https://openalex.org/W2062563626","https://openalex.org/W2076880245","https://openalex.org/W2081090017","https://openalex.org/W2082248073","https://openalex.org/W2084353434","https://openalex.org/W2092088062","https://openalex.org/W2101421856","https://openalex.org/W2110690400","https://openalex.org/W2123314710","https://openalex.org/W2137001928","https://openalex.org/W2149077119","https://openalex.org/W2163202592"],"related_works":["https://openalex.org/W2068308262","https://openalex.org/W2324698777","https://openalex.org/W4376226201","https://openalex.org/W2565166576","https://openalex.org/W2078484807","https://openalex.org/W2023560666","https://openalex.org/W2149077119","https://openalex.org/W2899364293","https://openalex.org/W2137001928","https://openalex.org/W2074472230"],"abstract_inverted_index":{"The":[0,58,71,92,130,147],"ability":[1],"to":[2,41,67,88,100,169],"manipulate":[3],"and":[4,11,15,27,46,51,74,79,126],"intervene":[5,42],"in":[6,24,43,102,119,154,179],"the":[7,20,33,44,62,68,103,117,120,134,137,150,155,167,172],"processes":[8,48,76],"of":[9,13,22,35,38,49,64,77,94,123,136,140,149,166,171],"assembly":[10,45,73,139,157],"disassembly":[12,47,75,135],"DNAs":[14,50,78,153],"nanoparticles":[16,23,53,81,125,141],"is":[17],"important":[18],"for":[19,175],"exploitation":[21],"medical":[25],"diagnostics":[26],"drug":[28],"delivery.":[29],"This":[30,111],"report":[31],"describes":[32],"results":[34,168],"an":[36],"investigation":[37],"a":[39,85,95,162],"strategy":[40],"gold":[52,80,124],"based":[54],"on":[55,107],"two":[56],"approaches.":[57],"first":[59],"approach":[60,132],"explores":[61],"viability":[63],"molecular":[65,96,173],"intervention":[66,101,174],"assembly-disassembly-reassembly":[69],"process.":[70],"temperature-induced":[72],"were":[82],"studied":[83],"as":[84],"model":[86],"system":[87],"illustrate":[89],"this":[90],"approach.":[91],"introduction":[93],"recognition":[97],"probe":[98],"leads":[99],"assembly-disassembly":[104],"process":[105,112],"depending":[106],"its":[108],"specific":[109],"biorecognition.":[110],"was":[113,158],"detected":[114],"by":[115,161],"monitoring":[116],"change":[118],"optical":[121],"properties":[122],"their":[127],"DNA":[128],"assemblies.":[129],"second":[131],"involves":[133],"DNA-linked":[138],"using":[142],"restriction":[143],"enzymes":[144],"(e.g.,":[145],"MspI).":[146],"presence":[148],"double":[151],"stranded":[152],"nanoparticle":[156],"also":[159,183],"substantiated":[160],"Southern":[163],"blot.":[164],"Implications":[165],"exploration":[170],"fine-tuning":[176],"interfacial":[177],"reactivities":[178],"DNA-based":[180],"bioassays":[181],"are":[182],"discussed.":[184]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
