{"id":"https://openalex.org/W2056766314","doi":"https://doi.org/10.1371/journal.pone.0058226","title":"Identification of Ovarian Cancer Metastatic miRNAs","display_name":"Identification of Ovarian Cancer Metastatic miRNAs","publication_year":2013,"publication_date":"2013-03-12","ids":{"openalex":"https://openalex.org/W2056766314","doi":"https://doi.org/10.1371/journal.pone.0058226","mag":"2056766314","pmid":"https://pubmed.ncbi.nlm.nih.gov/23554878","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3595263"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0058226","doi":"https://doi.org/10.1371/journal.pone.0058226","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0058226","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0058226&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0058226&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091564222","display_name":"Souriya Vang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Souriya Vang","raw_affiliation_strings":["Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, USA","Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, USA","institution_ids":["https://openalex.org/I27804330"]},{"raw_affiliation_string":"Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, United States of America","institution_ids":["https://openalex.org/I27804330"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017853294","display_name":"Hsin-Ta Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hsin-Ta Wu","raw_affiliation_strings":["Center for Computational Molecular Biology, Brown University, Providence, Rhode Island, United States of America","Department of Computer Science, Brown University, Providence, Rhode Island, United States of America","Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Computational Molecular Biology, Brown University, Providence, Rhode Island, United States of America","institution_ids":["https://openalex.org/I27804330"]},{"raw_affiliation_string":"Department of Computer Science, Brown University, Providence, Rhode Island, United States of America","institution_ids":["https://openalex.org/I27804330"]},{"raw_affiliation_string":"Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, United States of America","institution_ids":["https://openalex.org/I27804330"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033410011","display_name":"Andrew K. Fischer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew Fischer","raw_affiliation_strings":["Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, United States of America","institution_ids":["https://openalex.org/I27804330"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Daniel H. Miller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel H. Miller","raw_affiliation_strings":["Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, United States of America","institution_ids":["https://openalex.org/I27804330"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074954227","display_name":"Shannon Diane MacLaughlan","orcid":"https://orcid.org/0000-0001-7374-5773","observed_orcids":["https://orcid.org/0000-0001-7374-5773"]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]},{"id":"https://openalex.org/I4210133025","display_name":"Women & Infants Hospital of Rhode Island","ror":"https://ror.org/03z8sn326","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210133025"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shannon MacLaughlan","raw_affiliation_strings":["Program in Women's Oncology, Department of Obstetrics and Gynecology, Women and Infants' Hospital, Alpert Medical School of Brown University, Providence, Rhode Island, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Program in Women's Oncology, Department of Obstetrics and Gynecology, Women and Infants' Hospital, Alpert Medical School of Brown University, Providence, Rhode Island, United States of America","institution_ids":["https://openalex.org/I27804330","https://openalex.org/I4210133025"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038284533","display_name":"E. Michael Douglass","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elijah Douglass","raw_affiliation_strings":["Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, United States of America","institution_ids":["https://openalex.org/I27804330"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111980602","display_name":"Margaret M. Steinhoff","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]},{"id":"https://openalex.org/I4210133025","display_name":"Women & Infants Hospital of Rhode Island","ror":"https://ror.org/03z8sn326","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210133025"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Margaret Steinhoff","raw_affiliation_strings":["Department of Pathology, Women and Infants' Hospital, Alpert Medical School of Brown University, Providence, Rhode Island, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Women and Infants' Hospital, Alpert Medical School of Brown University, Providence, Rhode Island, United States of America","institution_ids":["https://openalex.org/I27804330","https://openalex.org/I4210133025"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050325886","display_name":"Colin C. Collins","orcid":"https://orcid.org/0000-0001-6148-6110","observed_orcids":["https://orcid.org/0000-0001-6148-6110","https://orcid.org/0009-0009-3987-4294"]},"institutions":[{"id":"https://openalex.org/I4405261103","display_name":"Vancouver Prostate Centre","ror":"https://ror.org/04skhpe58","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4405261103"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Colin Collins","raw_affiliation_strings":["Vancouver Prostate Centre, Vancouver, British Columbia, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vancouver Prostate Centre, Vancouver, British Columbia, Canada","institution_ids":["https://openalex.org/I4405261103"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002386330","display_name":"Peter J. Smith","orcid":"https://orcid.org/0000-0003-4400-6853","observed_orcids":["https://orcid.org/0000-0003-4400-6853","https://orcid.org/0000-0001-8707-2581"]},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Peter J. S. Smith","raw_affiliation_strings":["Institute of Life Sciences, University of Southampton, Southampton, England"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Life Sciences, University of Southampton, Southampton, England","institution_ids":["https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005661299","display_name":"Laurent Brard","orcid":"https://orcid.org/0000-0003-0065-1826","observed_orcids":["https://orcid.org/0000-0003-0065-1826"]},"institutions":[{"id":"https://openalex.org/I196729704","display_name":"SIU Medicine","ror":"https://ror.org/0232r4451","country_code":"US","type":"education","lineage":["https://openalex.org/I196729704","https://openalex.org/I2801502357"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laurent Brard","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Southern Illinois University School of Medicine, Springfield, Illinois, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Southern Illinois University School of Medicine, Springfield, Illinois, United States of America","institution_ids":["https://openalex.org/I196729704"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048946015","display_name":"Alexander S. Brodsky","orcid":"https://orcid.org/0000-0001-7357-5153","observed_orcids":["https://orcid.org/0000-0001-7357-5153"]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Alexander S. Brodsky","raw_affiliation_strings":["Center for Computational Molecular Biology, Brown University, Providence, Rhode Island, United States of America","Center for Genomics and Proteomics, Brown University, Providence, Rhode Island, United States of America","Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Computational Molecular Biology, Brown University, Providence, Rhode Island, United States of America","institution_ids":["https://openalex.org/I27804330"]},{"raw_affiliation_string":"Center for Genomics and Proteomics, Brown University, Providence, Rhode Island, United States of America","institution_ids":["https://openalex.org/I27804330"]},{"raw_affiliation_string":"Department of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, Rhode Island, United States of America","institution_ids":["https://openalex.org/I27804330"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5048946015"],"corresponding_institution_ids":["https://openalex.org/I27804330"],"apc_list":{"value":2382,"currency":"USD","value_usd":2382},"apc_paid":{"value":2382,"currency":"USD","value_usd":2382},"fwci":4.2156,"has_fulltext":true,"cited_by_count":90,"citation_normalized_percentile":{"value":0.94704451,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"8","issue":"3","first_page":"e58226","last_page":"e58226"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.008500000461935997,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/serous-epithelial-ovarian-cancer","display_name":"serous epithelial ovarian cancer","score":0.8510000109672546},{"id":"https://openalex.org/keywords/omental-metastasis","display_name":"omental metastasis","score":0.8379999995231628},{"id":"https://openalex.org/keywords/microrna-expression-profiling","display_name":"miRNA expression profiling","score":0.7919999957084656},{"id":"https://openalex.org/keywords/mir-146a","display_name":"miR-146a","score":0.9010000228881836},{"id":"https://openalex.org/keywords/mir-150","display_name":"miR-150","score":1.0},{"id":"https://openalex.org/keywords/mir-21","display_name":"miR-21","score":0.9990000128746033},{"id":"https://openalex.org/keywords/chemoresistance","display_name":"chemoresistance","score":0.5609999895095825},{"id":"https://openalex.org/keywords/cisplatin-resistance","display_name":"cisplatin resistance","score":0.828000009059906},{"id":"https://openalex.org/keywords/drug-tolerance","display_name":"drug tolerance","score":0.5040000081062317},{"id":"https://openalex.org/keywords/residual-tumor-cells","display_name":"residual tumor cells","score":0.578000009059906}],"concepts":[{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.8475546836853027},{"id":"https://openalex.org/C2780427987","wikidata":"https://www.wikidata.org/wiki/Q172341","display_name":"Ovarian cancer","level":3,"score":0.7580113410949707},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.6305587291717529},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5568220615386963},{"id":"https://openalex.org/C150173356","wikidata":"https://www.wikidata.org/wiki/Q6144101","display_name":"Serous fluid","level":2,"score":0.5562272667884827},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5406754016876221},{"id":"https://openalex.org/C2778239845","wikidata":"https://www.wikidata.org/wiki/Q412415","display_name":"Cisplatin","level":3,"score":0.4903907775878906},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.42870375514030457},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.40914979577064514},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3911622166633606},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.35417890548706055},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3272547721862793},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2839896082878113},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1386214792728424},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002945","descriptor_name":"Cisplatin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009362","descriptor_name":"Neoplasm Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010051","descriptor_name":"Ovarian Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010051","descriptor_name":"Ovarian Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012334","descriptor_name":"RNA, Neoplasm","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018874","descriptor_name":"Spheroids, Cellular","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018874","descriptor_name":"Spheroids, Cellular","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D019008","descriptor_name":"Drug Resistance, Neoplasm","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1371/journal.pone.0058226","doi":"https://doi.org/10.1371/journal.pone.0058226","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0058226","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0058226&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2612747","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3595263","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3595263","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3595263","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmid:23554878","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23554878","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Clinical Trial"},{"id":"pmh:oai:eprints.soton.ac.uk:356616","doi":null,"is_oa":false,"landing_page_url":"http://doi.org/10.1371/journal.pone.0058226>).","pdf_url":null,"source":{"id":"https://openalex.org/S4306401019","display_name":"ePrints Soton (University of Southampton)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I43439940","host_organization_name":"University of Southampton","host_organization_lineage":["https://openalex.org/I43439940"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:doaj.org/article:1ac9376eb986475b82cc936e67539c8d","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/1ac9376eb986475b82cc936e67539c8d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 8, Iss 3, p e58226 (2013)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/650471","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/Identification_of_Ovarian_Cancer_Metastatic_miRNAs__/650471","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0058226","doi":"https://doi.org/10.1371/journal.pone.0058226","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0058226","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0058226&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2443951001","display_name":"BioCurrents Research Center","funder_award_id":"P41RR001395","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G2529235680","display_name":"Center for Cancer Signaling Networks","funder_award_id":"P30RR031153","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G4286885007","display_name":"Shared High-throughput DNA sequencer for the Brown University Community","funder_award_id":"S10RR027634","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G6367052362","display_name":null,"funder_award_id":"P20RR0118/28","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G8778388363","display_name":"Rhode Island EPSCoR: Catalyzing a Research, Education and Innovation Network","funder_award_id":"0554548","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320309070","display_name":"Brown University","ror":"https://ror.org/05gq02987"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2056766314.pdf","grobid_xml":"https://content.openalex.org/works/W2056766314.grobid-xml"},"referenced_works_count":52,"referenced_works":["https://openalex.org/W92784205","https://openalex.org/W154163542","https://openalex.org/W1986910874","https://openalex.org/W1988163167","https://openalex.org/W1998260014","https://openalex.org/W1999360191","https://openalex.org/W1999439818","https://openalex.org/W2000102678","https://openalex.org/W2004834404","https://openalex.org/W2017435063","https://openalex.org/W2022753987","https://openalex.org/W2024704386","https://openalex.org/W2041237929","https://openalex.org/W2042633087","https://openalex.org/W2044967196","https://openalex.org/W2045881743","https://openalex.org/W2047311008","https://openalex.org/W2049058992","https://openalex.org/W2049514205","https://openalex.org/W2051808614","https://openalex.org/W2053568631","https://openalex.org/W2056569074","https://openalex.org/W2057151160","https://openalex.org/W2073527066","https://openalex.org/W2075860675","https://openalex.org/W2078354424","https://openalex.org/W2080254290","https://openalex.org/W2083381199","https://openalex.org/W2092868756","https://openalex.org/W2093585643","https://openalex.org/W2101675014","https://openalex.org/W2105996541","https://openalex.org/W2106391833","https://openalex.org/W2108541764","https://openalex.org/W2117402284","https://openalex.org/W2117472344","https://openalex.org/W2117965440","https://openalex.org/W2129286473","https://openalex.org/W2131268931","https://openalex.org/W2137151361","https://openalex.org/W2142139829","https://openalex.org/W2143145944","https://openalex.org/W2147469407","https://openalex.org/W2147478966","https://openalex.org/W2149785901","https://openalex.org/W2150823776","https://openalex.org/W2156010403","https://openalex.org/W2159778842","https://openalex.org/W2161222316","https://openalex.org/W2165836181","https://openalex.org/W2166667895","https://openalex.org/W2169895148"],"related_works":["https://openalex.org/W7096434320","https://openalex.org/W2001710827","https://openalex.org/W2020546654","https://openalex.org/W2800158025","https://openalex.org/W2780191894","https://openalex.org/W2314690876","https://openalex.org/W2118153758","https://openalex.org/W2209686463","https://openalex.org/W2019007380","https://openalex.org/W3017007417"],"abstract_inverted_index":{"Serous":[0],"epithelial":[1],"ovarian":[2,22],"cancer":[3,23,167],"(EOC)":[4],"patients":[5,61],"often":[6],"succumb":[7],"to":[8,28,78],"aggressive":[9],"metastatic":[10],"disease,":[11],"yet":[12],"little":[13],"is":[14],"known":[15],"about":[16],"the":[17,46,125,148,192],"behavior":[18],"and":[19,37,54,83,115,122,151,159,179],"genetics":[20],"of":[21,50,103,127,147,184,191,194],"metastasis.":[24],"Here,":[25],"we":[26],"aim":[27],"understand":[29],"how":[30,38],"omental":[31,57,75,97,155,170],"metastases":[32,58],"differ":[33],"from":[34,59],"primary":[35,51,79,90,177],"tumors":[36,53,91,171],"these":[39,185],"differences":[40],"may":[41,187],"influence":[42],"chemotherapy.":[43],"We":[44,67,111],"analyzed":[45],"miRNA":[47,63],"expression":[48,73,87,95,102],"profiles":[49],"EOC":[52],"their":[55],"respective":[56],"9":[60],"using":[62],"Taqman":[64],"qPCR":[65],"arrays.":[66],"find":[68,112],"17":[69],"miRNAs":[70,174],"with":[71,92,99,136],"differential":[72],"in":[74,88,96,154,169],"lesions":[76],"compared":[77],"tumors.":[80],"miR-21,":[81],"miR-150,":[82,152],"miR-146a":[84,116,121,150],"have":[85],"low":[86],"most":[89],"significantly":[93],"increased":[94],"lesions,":[98,156],"concomitant":[100],"decreased":[101],"predicted":[104],"mRNA":[105,109],"targets":[106],"based":[107],"on":[108],"expression.":[110],"that":[113,143,166,180],"miR-150":[114,123],"mediate":[117],"spheroid":[118],"size.":[119],"Both":[120],"increase":[124,160],"number":[126],"residual":[128],"surviving":[129],"cells":[130,168],"by":[131],"2-4":[132],"fold":[133],"when":[134],"challenged":[135],"lethal":[137],"cisplatin":[138],"concentrations.":[139],"These":[140],"observations":[141,164],"suggest":[142,165],"at":[144,181],"least":[145,182],"two":[146],"miRNAs,":[149],"up-regulated":[153],"stimulate":[157],"survival":[158],"drug":[161,195],"tolerance.":[162],"Our":[163],"express":[172],"key":[173],"differently":[175],"than":[176],"tumors,":[178],"some":[183],"microRNAs":[186],"be":[188],"critical":[189],"regulators":[190],"emergence":[193],"resistant":[196],"disease.":[197]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":14},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":12},{"year":2013,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
