{"id":"https://openalex.org/W2056742016","doi":"https://doi.org/10.1093/eurheartj/18.suppl_d.9","title":"Dobutamine stress echocardiography","display_name":"Dobutamine stress echocardiography","publication_year":1997,"publication_date":"1997-06-02","ids":{"openalex":"https://openalex.org/W2056742016","doi":"https://doi.org/10.1093/eurheartj/18.suppl_d.9","mag":"2056742016","pmid":"https://pubmed.ncbi.nlm.nih.gov/9183605"},"language":"en","primary_location":{"id":"doi:10.1093/eurheartj/18.suppl_d.9","doi":"https://doi.org/10.1093/eurheartj/18.suppl_d.9","is_oa":false,"landing_page_url":"https://doi.org/10.1093/eurheartj/18.suppl_d.9","pdf_url":null,"source":{"id":"https://openalex.org/S181568219","display_name":"European Heart Journal","issn_l":"0195-668X","issn":["0195-668X","1522-9645"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Heart Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026472494","display_name":"Wolfgang Krahwinkel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I155976169","display_name":"Witten/Herdecke University","ror":"https://ror.org/00yq55g44","country_code":"DE","type":"education","lineage":["https://openalex.org/I155976169"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"W. Krahwinkel","raw_affiliation_strings":["Wuppertal Heart Centre, Department of Cardiology, University of Witten/Herdecke, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wuppertal Heart Centre, Department of Cardiology, University of Witten/Herdecke, Germany","institution_ids":["https://openalex.org/I155976169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082402340","display_name":"Thomas Ketteler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I155976169","display_name":"Witten/Herdecke University","ror":"https://ror.org/00yq55g44","country_code":"DE","type":"education","lineage":["https://openalex.org/I155976169"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"T. Ketteler","raw_affiliation_strings":["Wuppertal Heart Centre, Department of Cardiology, University of Witten/Herdecke Wuppertal, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wuppertal Heart Centre, Department of Cardiology, University of Witten/Herdecke Wuppertal, Germany","institution_ids":["https://openalex.org/I155976169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009633793","display_name":"J. Godke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I155976169","display_name":"Witten/Herdecke University","ror":"https://ror.org/00yq55g44","country_code":"DE","type":"education","lineage":["https://openalex.org/I155976169"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"J. Godke","raw_affiliation_strings":["Wuppertal Heart Centre, Department of Cardiology, University of Witten/Herdecke Wuppertal, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wuppertal Heart Centre, Department of Cardiology, University of Witten/Herdecke Wuppertal, Germany","institution_ids":["https://openalex.org/I155976169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014530020","display_name":"Judith Wolfertz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I155976169","display_name":"Witten/Herdecke University","ror":"https://ror.org/00yq55g44","country_code":"DE","type":"education","lineage":["https://openalex.org/I155976169"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"J. Wolfertz","raw_affiliation_strings":["Wuppertal Heart Centre, Department of Cardiology, University of Witten/Herdecke Wuppertal, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wuppertal Heart Centre, Department of Cardiology, University of Witten/Herdecke Wuppertal, Germany","institution_ids":["https://openalex.org/I155976169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065157149","display_name":"Ludger J. Ulbricht","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I155976169","display_name":"Witten/Herdecke University","ror":"https://ror.org/00yq55g44","country_code":"DE","type":"education","lineage":["https://openalex.org/I155976169"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"L. J. Ulbricht","raw_affiliation_strings":["Wuppertal Heart Centre, Department of Cardiology, University of Witten/Herdecke Wuppertal, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wuppertal Heart Centre, Department of Cardiology, University of Witten/Herdecke Wuppertal, Germany","institution_ids":["https://openalex.org/I155976169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081453631","display_name":"Ingo Krakau","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I155976169","display_name":"Witten/Herdecke University","ror":"https://ror.org/00yq55g44","country_code":"DE","type":"education","lineage":["https://openalex.org/I155976169"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"I. Krakau","raw_affiliation_strings":["Wuppertal Heart Centre, Department of Cardiology, University of Witten/Herdecke Wuppertal, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wuppertal Heart Centre, Department of Cardiology, University of Witten/Herdecke Wuppertal, Germany","institution_ids":["https://openalex.org/I155976169"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112133655","display_name":"H G\u00fclker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I155976169","display_name":"Witten/Herdecke University","ror":"https://ror.org/00yq55g44","country_code":"DE","type":"education","lineage":["https://openalex.org/I155976169"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"H. Gulker","raw_affiliation_strings":["Wuppertal Heart Centre, Department of Cardiology, University of Witten/Herdecke Wuppertal, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wuppertal Heart Centre, Department of Cardiology, University of Witten/Herdecke Wuppertal, Germany","institution_ids":["https://openalex.org/I155976169"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5026472494"],"corresponding_institution_ids":["https://openalex.org/I155976169"],"apc_list":{"value":5240,"currency":"EUR","value_usd":5922},"apc_paid":null,"fwci":3.1947,"has_fulltext":false,"cited_by_count":52,"citation_normalized_percentile":{"value":0.9081129,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"18","issue":"suppl D","first_page":"9","last_page":"15"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.006899999920278788,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13381","display_name":"Heart rate and cardiovascular health","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dobutamine-stress-echocardiography","display_name":"dobutamine stress echocardiography","score":0.9879999756813049},{"id":"https://openalex.org/keywords/dobutamine","display_name":"dobutamine","score":0.9729999899864197},{"id":"https://openalex.org/keywords/beta-adrenergic-stimulation","display_name":"beta-adrenergic stimulation","score":0.8799999952316284},{"id":"https://openalex.org/keywords/myocardial-ischemia","display_name":"myocardial ischemia","score":0.9399999976158142},{"id":"https://openalex.org/keywords/coronary-artery-obstruction","display_name":"coronary artery obstruction","score":0.8230000138282776},{"id":"https://openalex.org/keywords/wall-motion-abnormalities","display_name":"wall motion abnormalities","score":0.8730000257492065},{"id":"https://openalex.org/keywords/myocardial-viability","display_name":"myocardial viability","score":0.9279999732971191},{"id":"https://openalex.org/keywords/inotropic-reserve","display_name":"inotropic reserve","score":0.8230000138282776},{"id":"https://openalex.org/keywords/atropine","display_name":"atropine","score":0.8669999837875366}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9292645454406738},{"id":"https://openalex.org/C2781185063","wikidata":"https://www.wikidata.org/wiki/Q422782","display_name":"Dobutamine","level":3,"score":0.9286705851554871},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.7622436285018921},{"id":"https://openalex.org/C158328960","wikidata":"https://www.wikidata.org/wiki/Q1088369","display_name":"Chronotropic","level":4,"score":0.7170283198356628},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6985822916030884},{"id":"https://openalex.org/C2909814191","wikidata":"https://www.wikidata.org/wiki/Q1350700","display_name":"Stress Echocardiography","level":3,"score":0.6562920212745667},{"id":"https://openalex.org/C155710745","wikidata":"https://www.wikidata.org/wiki/Q575278","display_name":"Inotrope","level":2,"score":0.6498069763183594},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.5148996114730835},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.4855012893676758},{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.4438779652118683},{"id":"https://openalex.org/C2775859210","wikidata":"https://www.wikidata.org/wiki/Q26272","display_name":"Atropine","level":2,"score":0.42103099822998047},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.33354073762893677},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.25862669944763184},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.2318854033946991}],"mesh":[{"descriptor_ui":"D000319","descriptor_name":"Adrenergic beta-Antagonists","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004280","descriptor_name":"Dobutamine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D004452","descriptor_name":"Echocardiography","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D004452","descriptor_name":"Echocardiography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005080","descriptor_name":"Exercise Test","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D005080","descriptor_name":"Exercise Test","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/eurheartj/18.suppl_d.9","doi":"https://doi.org/10.1093/eurheartj/18.suppl_d.9","is_oa":false,"landing_page_url":"https://doi.org/10.1093/eurheartj/18.suppl_d.9","pdf_url":null,"source":{"id":"https://openalex.org/S181568219","display_name":"European Heart Journal","issn_l":"0195-668X","issn":["0195-668X","1522-9645"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Heart Journal","raw_type":"journal-article"},{"id":"pmid:9183605","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9183605","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European heart journal","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2411971173","https://openalex.org/W2410655100","https://openalex.org/W3001681910","https://openalex.org/W2371571195","https://openalex.org/W2062454699","https://openalex.org/W2032041442","https://openalex.org/W2750816323","https://openalex.org/W97139510","https://openalex.org/W2408319637","https://openalex.org/W2182541148"],"abstract_inverted_index":{"Dobutamine":[0],"is":[1,10,30,80],"a":[2,60,73,108],"synthetic":[3],"catecholamine":[4],"with":[5],"predominant":[6],"beta-stimulation.":[7],"Its":[8],"half-life":[9],"approximately":[11],"2":[12],"min.":[13],"The":[14,141],"positive":[15,109],"chronotropic":[16],"and":[17,57,118,136],"inotropic":[18,110],"effects":[19],"of":[20,54,63,76,87,94,99,126,150],"dobutamine":[21,46,117,127],"induce":[22],"myocardial":[23,105,134,139,152],"ischaemia":[24,33,135,153],"if":[25,154,163],"significant":[26],"coronary":[27],"artery":[28],"obstruction":[29],"present.":[31],"Regional":[32],"produces":[34],"regional":[35],"wall":[36,89],"motion":[37,90],"abnormalities":[38],"which":[39,112],"can":[40,113],"be":[41,114,145],"detected":[42,119],"by":[43,116,120],"echocardiography.":[44,121,174],"Most":[45],"stress":[47,128],"protocols":[48],"start":[49],"at":[50],"an":[51],"infusion":[52],"rate":[53],"5":[55],"micrograms.kg-1.min-1":[56],"increase":[58,70],"to":[59,68,131,137,158,166],"peak":[61],"dose":[62],"40":[64],"or":[65,97,162],"50":[66],"micrograms.kg-1.min-1;":[67],"further":[69],"heart":[71,102],"rate,":[72],"bolus":[74],"injection":[75],"0.25-1.0":[77],"mg":[78],"atropine":[79],"added.":[81],"Test":[82],"endpoints":[83],"are":[84,130,156],"the":[85,92,100,124,148],"detection":[86,149],"new":[88],"abnormalities,":[91],"occurrence":[93],"severe":[95],"complications":[96],"achievement":[98],"target":[101],"rate.":[103],"Viable":[104],"regions":[106],"have":[107],"reserve,":[111],"stimulated":[115],"Indications":[122],"for":[123,147],"use":[125],"echocardiography":[129],"prove":[132],"stress-inducible":[133],"detect":[138],"viability.":[140],"test":[142,170],"should":[143],"only":[144],"performed":[146],"stress-induced":[151],"patients":[155,164],"unable":[157],"undergo":[159],"exercise":[160,173],"echocardiography,":[161],"fail":[165],"reach":[167],"their":[168],"required":[169],"level":[171],"in":[172]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":6},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}