{"id":"https://openalex.org/W2056687236","doi":"https://doi.org/10.7150/thno.4928","title":"Therapeutic Evaluation of microRNAs by Molecular Imaging","display_name":"Therapeutic Evaluation of microRNAs by Molecular Imaging","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2056687236","doi":"https://doi.org/10.7150/thno.4928","mag":"2056687236","pmid":"https://pubmed.ncbi.nlm.nih.gov/24396507","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3881098"},"language":"en","primary_location":{"id":"doi:10.7150/thno.4928","doi":"https://doi.org/10.7150/thno.4928","is_oa":true,"landing_page_url":"https://doi.org/10.7150/thno.4928","pdf_url":"https://www.thno.org/v03p0964.pdf","source":{"id":"https://openalex.org/S2482500137","display_name":"Theranostics","issn_l":"1838-7640","issn":["1838-7640"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317973","host_organization_name":"Ivyspring International Publisher","host_organization_lineage":["https://openalex.org/P4310317973"],"host_organization_lineage_names":["Ivyspring International Publisher"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Theranostics","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.thno.org/v03p0964.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036552090","display_name":"Thillai V. Sekar","orcid":"https://orcid.org/0000-0002-2919-8802","observed_orcids":["https://orcid.org/0000-0002-2919-8802"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thillai V. Sekar","raw_affiliation_strings":["1. Molecular Imaging Program at Stanford, Bio-X Program, Department of Radiology, Stanford University School of Medicine, Stanford, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1. Molecular Imaging Program at Stanford, Bio-X Program, Department of Radiology, Stanford University School of Medicine, Stanford, California, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050272646","display_name":"Kunka Mohanram Ramkumar","orcid":"https://orcid.org/0000-0001-5450-902X","observed_orcids":["https://orcid.org/0000-0001-5450-902X","https://orcid.org/0009-0008-5353-5259","https://orcid.org/0000-0003-4209-4896"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ramkumar Kunga Mohanram","raw_affiliation_strings":["1. Molecular Imaging Program at Stanford, Bio-X Program, Department of Radiology, Stanford University School of Medicine, Stanford, California, USA. ; 2. Current address: SRM Research Institute, SRM University, Kattankulathur- 603 203, Tamilnadu, India","Stanford University, Stanford, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1. Molecular Imaging Program at Stanford, Bio-X Program, Department of Radiology, Stanford University School of Medicine, Stanford, California, USA. ; 2. Current address: SRM Research Institute, SRM University, Kattankulathur- 603 203, Tamilnadu, India","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"raw_affiliation_string":"Stanford University, Stanford, United States","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091345173","display_name":"Kira Foygel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kira Foygel","raw_affiliation_strings":["1. Molecular Imaging Program at Stanford, Bio-X Program, Department of Radiology, Stanford University School of Medicine, Stanford, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1. Molecular Imaging Program at Stanford, Bio-X Program, Department of Radiology, Stanford University School of Medicine, Stanford, California, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018880989","display_name":"Ramasamy Paulmurugan","orcid":"https://orcid.org/0000-0001-7155-4738","observed_orcids":["https://orcid.org/0000-0001-7155-4738"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ramasamy Paulmurugan","raw_affiliation_strings":["1. Molecular Imaging Program at Stanford, Bio-X Program, Department of Radiology, Stanford University School of Medicine, Stanford, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1. Molecular Imaging Program at Stanford, Bio-X Program, Department of Radiology, Stanford University School of Medicine, Stanford, California, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5018880989"],"corresponding_institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"],"apc_list":{"value":2500,"currency":"AUD","value_usd":1671},"apc_paid":{"value":2500,"currency":"AUD","value_usd":1671},"fwci":0.36,"has_fulltext":true,"cited_by_count":23,"citation_normalized_percentile":{"value":0.34682081,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"3","issue":"12","first_page":"964","last_page":"985"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9711999893188477,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9711999893188477,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.013500000350177288,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.9980000257492065},{"id":"https://openalex.org/keywords/microrna-therapy","display_name":"miRNA-based therapy","score":0.7390000224113464},{"id":"https://openalex.org/keywords/molecular-imaging","display_name":"molecular imaging","score":0.9309999942779541},{"id":"https://openalex.org/keywords/cancer","display_name":"cancer","score":0.656000018119812},{"id":"https://openalex.org/keywords/bioluminescence-imaging","display_name":"bioluminescence imaging","score":0.9810000061988831},{"id":"https://openalex.org/keywords/chemiluminescence","display_name":"chemiluminescence","score":0.8889999985694885},{"id":"https://openalex.org/keywords/microrna-target-genes","display_name":"miRNA target genes","score":0.7200000286102295},{"id":"https://openalex.org/keywords/untranslated-regions","display_name":"untranslated regions","score":0.6589999794960022},{"id":"https://openalex.org/keywords/microrna-processing","display_name":"microRNA processing","score":0.8930000066757202},{"id":"https://openalex.org/keywords/tumor-suppressor-genes","display_name":"tumor suppressor","score":0.5870000123977661},{"id":"https://openalex.org/keywords/oncogenes","display_name":"oncogenes","score":0.875},{"id":"https://openalex.org/keywords/targeted-drugs","display_name":"targeted therapeutics","score":0.6349999904632568}],"concepts":[{"id":"https://openalex.org/C136339569","wikidata":"https://www.wikidata.org/wiki/Q1142297","display_name":"Molecular imaging","level":3,"score":0.6566900610923767},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.6043975353240967},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.40911683440208435},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3975023329257965},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.25108206272125244},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.111136794090271},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0841616690158844},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016903","descriptor_name":"Drug Monitoring","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D057054","descriptor_name":"Molecular Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D061848","descriptor_name":"Optical Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.7150/thno.4928","doi":"https://doi.org/10.7150/thno.4928","is_oa":true,"landing_page_url":"https://doi.org/10.7150/thno.4928","pdf_url":"https://www.thno.org/v03p0964.pdf","source":{"id":"https://openalex.org/S2482500137","display_name":"Theranostics","issn_l":"1838-7640","issn":["1838-7640"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317973","host_organization_name":"Ivyspring International Publisher","host_organization_lineage":["https://openalex.org/P4310317973"],"host_organization_lineage_names":["Ivyspring International Publisher"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Theranostics","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2869864","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3881098","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3881098","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3881098","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Theranostics","raw_type":"Text"},{"id":"pmid:24396507","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24396507","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Theranostics","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.7150/thno.4928","doi":"https://doi.org/10.7150/thno.4928","is_oa":true,"landing_page_url":"https://doi.org/10.7150/thno.4928","pdf_url":"https://www.thno.org/v03p0964.pdf","source":{"id":"https://openalex.org/S2482500137","display_name":"Theranostics","issn_l":"1838-7640","issn":["1838-7640"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317973","host_organization_name":"Ivyspring International Publisher","host_organization_lineage":["https://openalex.org/P4310317973"],"host_organization_lineage_names":["Ivyspring International Publisher"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Theranostics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9763000011444092}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1178628110","display_name":"Molecular Sensors for Imaging Histone Methylations in Living Animals","funder_award_id":"R01CA161091","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G6985161458","display_name":null,"funder_award_id":"RO1 CA161091","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332427","display_name":"School of Medicine, Stanford University","ror":"https://ror.org/00f54p054"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2056687236.pdf","grobid_xml":"https://content.openalex.org/works/W2056687236.grobid-xml"},"referenced_works_count":177,"referenced_works":["https://openalex.org/W330725844","https://openalex.org/W1520066951","https://openalex.org/W1553045433","https://openalex.org/W1566823022","https://openalex.org/W1584433563","https://openalex.org/W1606047888","https://openalex.org/W1861916783","https://openalex.org/W1965371218","https://openalex.org/W1966448677","https://openalex.org/W1967007963","https://openalex.org/W1970829776","https://openalex.org/W1971385615","https://openalex.org/W1972989638","https://openalex.org/W1975989411","https://openalex.org/W1976324983","https://openalex.org/W1976924899","https://openalex.org/W1979912768","https://openalex.org/W1980269624","https://openalex.org/W1982535740","https://openalex.org/W1983991097","https://openalex.org/W1984085632","https://openalex.org/W1985563073","https://openalex.org/W1990786114","https://openalex.org/W1992272392","https://openalex.org/W1993241025","https://openalex.org/W1995689125","https://openalex.org/W1996350041","https://openalex.org/W2001770239","https://openalex.org/W2004527136","https://openalex.org/W2005790499","https://openalex.org/W2005942192","https://openalex.org/W2006173503","https://openalex.org/W2007276591","https://openalex.org/W2008955962","https://openalex.org/W2009006896","https://openalex.org/W2010215928","https://openalex.org/W2013411499","https://openalex.org/W2014064723","https://openalex.org/W2014518368","https://openalex.org/W2014869583","https://openalex.org/W2018216617","https://openalex.org/W2020085463","https://openalex.org/W2021936364","https://openalex.org/W2023620453","https://openalex.org/W2025449301","https://openalex.org/W2027873015","https://openalex.org/W2028945916","https://openalex.org/W2031147075","https://openalex.org/W2033993004","https://openalex.org/W2035369297","https://openalex.org/W2037631027","https://openalex.org/W2039738300","https://openalex.org/W2040463432","https://openalex.org/W2040827479","https://openalex.org/W2042027879","https://openalex.org/W2042855895","https://openalex.org/W2044406386","https://openalex.org/W2044601473","https://openalex.org/W2045998598","https://openalex.org/W2047529648","https://openalex.org/W2048577371","https://openalex.org/W2049260350","https://openalex.org/W2051227958","https://openalex.org/W2051352765","https://openalex.org/W2051512506","https://openalex.org/W2054551605","https://openalex.org/W2055585366","https://openalex.org/W2056302937","https://openalex.org/W2056868280","https://openalex.org/W2058252240","https://openalex.org/W2058531774","https://openalex.org/W2060221489","https://openalex.org/W2060459012","https://openalex.org/W2061452886","https://openalex.org/W2062290101","https://openalex.org/W2062954242","https://openalex.org/W2064016484","https://openalex.org/W2064584942","https://openalex.org/W2069104846","https://openalex.org/W2071925802","https://openalex.org/W2072543946","https://openalex.org/W2074713811","https://openalex.org/W2075692189","https://openalex.org/W2076987945","https://openalex.org/W2077724030","https://openalex.org/W2078845383","https://openalex.org/W2080725243","https://openalex.org/W2083381199","https://openalex.org/W2084400739","https://openalex.org/W2084453192","https://openalex.org/W2085642771","https://openalex.org/W2085674255","https://openalex.org/W2086809547","https://openalex.org/W2088743024","https://openalex.org/W2089858439","https://openalex.org/W2090749716","https://openalex.org/W2090901462","https://openalex.org/W2093557716","https://openalex.org/W2097876071","https://openalex.org/W2098150383","https://openalex.org/W2099099087","https://openalex.org/W2099439420","https://openalex.org/W2101077751","https://openalex.org/W2102068103","https://openalex.org/W2102482931","https://openalex.org/W2102824849","https://openalex.org/W2103052577","https://openalex.org/W2103177465","https://openalex.org/W2103211592","https://openalex.org/W2104610341","https://openalex.org/W2104905829","https://openalex.org/W2106929712","https://openalex.org/W2109341131","https://openalex.org/W2110064443","https://openalex.org/W2111635840","https://openalex.org/W2111990378","https://openalex.org/W2113707167","https://openalex.org/W2116000203","https://openalex.org/W2116591838","https://openalex.org/W2116627727","https://openalex.org/W2117009425","https://openalex.org/W2117976441","https://openalex.org/W2117991391","https://openalex.org/W2118783357","https://openalex.org/W2120055234","https://openalex.org/W2120965929","https://openalex.org/W2121133384","https://openalex.org/W2123168045","https://openalex.org/W2123218517","https://openalex.org/W2123827665","https://openalex.org/W2124158936","https://openalex.org/W2125460987","https://openalex.org/W2128674168","https://openalex.org/W2128768066","https://openalex.org/W2131153559","https://openalex.org/W2131596261","https://openalex.org/W2131722060","https://openalex.org/W2131964760","https://openalex.org/W2132938339","https://openalex.org/W2133816851","https://openalex.org/W2134353492","https://openalex.org/W2135314242","https://openalex.org/W2138155367","https://openalex.org/W2139427344","https://openalex.org/W2140017455","https://openalex.org/W2140236265","https://openalex.org/W2142221925","https://openalex.org/W2144038313","https://openalex.org/W2144840682","https://openalex.org/W2145864981","https://openalex.org/W2148422935","https://openalex.org/W2149992636","https://openalex.org/W2150881491","https://openalex.org/W2153661308","https://openalex.org/W2154570280","https://openalex.org/W2157754963","https://openalex.org/W2157968886","https://openalex.org/W2159730993","https://openalex.org/W2160423582","https://openalex.org/W2161957137","https://openalex.org/W2166695303","https://openalex.org/W2167557255","https://openalex.org/W2167919777","https://openalex.org/W2168458927","https://openalex.org/W2168494970","https://openalex.org/W2168993612","https://openalex.org/W2169621060","https://openalex.org/W2171362256","https://openalex.org/W2171985637","https://openalex.org/W2172255406","https://openalex.org/W2314750522","https://openalex.org/W2322539745","https://openalex.org/W2970890090","https://openalex.org/W3144430489","https://openalex.org/W3152116152","https://openalex.org/W4249602330","https://openalex.org/W4300551099"],"related_works":["https://openalex.org/W2186250537","https://openalex.org/W7096505671","https://openalex.org/W7097306699","https://openalex.org/W2815220571","https://openalex.org/W2597435427","https://openalex.org/W3119795027","https://openalex.org/W2033239367","https://openalex.org/W3032092923","https://openalex.org/W2150965189","https://openalex.org/W2389336383"],"abstract_inverted_index":{"MicroRNAs":[0],"(miRNAs)":[1],"function":[2,103],"as":[3,49,68,169,185,333],"regulatory":[4],"molecules":[5,55],"of":[6,27,30,33,54,77,92,107,114,129,139,145,176,182,213,226,243,264,281,291,312],"gene":[7,108],"expression":[8,76,109,241],"with":[9],"multifaceted":[10],"activities":[11],"that":[12,87,193],"exhibit":[13],"direct":[14],"or":[15,71,294],"indirect":[16],"oncogenic":[17,115],"properties,":[18],"which":[19,218],"promote":[20],"cell":[21,341],"proliferation,":[22],"differentiation,":[23],"and":[24,45,83,117,156,160,245,252,268,315],"the":[25,64,75,90,180,223,240,260,265,279,288,295],"development":[26,280],"different":[28,78,319],"types":[29],"cancers.":[31,146,231],"Because":[32],"their":[34,126,157,246,335],"extensive":[35],"functional":[36,289],"involvement":[37,317],"in":[38,173,221,229,300,318,328,338],"many":[39],"cellular":[40,177,320],"processes,":[41],"under":[42],"both":[43],"normal":[44],"pathological":[46],"conditions":[47],"such":[48,332],"various":[50,214,230,310,339],"cancers,":[51],"this":[52,207],"class":[53,138],"holds":[56],"particular":[57],"interest":[58],"for":[59,142,203,238,278,327],"cancer":[60,99,340],"research.":[61,205],"MiRNAs":[62],"possess":[63],"ability":[65],"to":[66,97,121,134,154,200,259,286,308],"act":[67],"tumor":[69,93],"suppressors":[70],"oncogenes":[72],"by":[73,104,249],"regulating":[74],"apoptotic":[79],"proteins,":[80],"kinases,":[81],"oncogenes,":[82],"other":[84],"molecular":[85,158,215],"mechanisms":[86,159],"can":[88],"cause":[89],"onset":[91],"development.":[94],"In":[95,206],"contrast":[96],"current":[98],"medicines,":[100],"miRNA-based":[101],"therapies":[102],"subtle":[105],"repression":[106],"on":[110],"a":[111,136,143,174,211],"large":[112],"number":[113],"factors,":[116],"therefore":[118],"are":[119,132,162,167,197,219],"anticipated":[120],"be":[122,201],"highly":[123],"efficacious.":[124],"Given":[125],"unique":[127],"mechanism":[128],"action,":[130],"miRNAs":[131,150,244,257,297],"likely":[133],"yield":[135],"new":[137],"targeted":[140],"therapeutics":[141],"variety":[144,175],"More":[147],"than":[148],"thousand":[149],"have":[151,234,305],"been":[152,236,276,306],"identified":[153],"date,":[155],"functions":[161],"well":[163],"studied.":[164],"Furthermore,":[165],"they":[166],"established":[168],"compelling":[170],"therapeutic":[171,186,224,336],"targets":[172],"complications.":[178],"However,":[179],"notion":[181],"using":[183],"them":[184],"tool":[187],"was":[188],"proposed":[189],"only":[190],"recently,":[191],"given":[192],"modern":[194],"imaging":[195,216,254,284,303,331],"methods":[196,233,324],"just":[198],"beginning":[199],"deployed":[202],"miRNA":[204,313,330],"review,":[208],"we":[209],"present":[210],"summary":[212],"methods,":[217],"instrumental":[220],"revealing":[222],"potential":[225],"miRNAs,":[227,293],"especially":[228],"Imaging":[232],"recently":[235],"developed":[237,326],"monitoring":[239,334],"levels":[242],"target":[247,266,270],"genes":[248,271],"fluorescence-,":[250],"bioluminescence-":[251],"chemiluminescence-based":[253],"techniques.":[255],"Mature":[256],"bind":[258],"untranslated":[261],"regions":[262],"(UTRs)":[263],"mRNAs":[267],"regulate":[269],"expressions.":[272],"This":[273],"concept":[274],"has":[275],"used":[277,307],"fluorescent":[282],"reporter-based":[283],"strategies":[285,304],"monitor":[287],"status":[290],"endogenous":[292],"respective":[296],"transiently":[298],"co-expressed":[299],"cells.":[301],"Bioluminescence-based":[302],"investigate":[309],"stages":[311],"processing":[314],"its":[316],"processes.":[321],"Similarly,":[322],"chemiluminsecence":[323],"were":[325],"vitro":[329],"roles":[337],"lines.":[342]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
