{"id":"https://openalex.org/W2056528138","doi":"https://doi.org/10.1007/bf00660313","title":"Chorion genecis-regulatory DNA restricts tissue specificity of reporter gene expression in transformedDrosophila","display_name":"Chorion genecis-regulatory DNA restricts tissue specificity of reporter gene expression in transformedDrosophila","publication_year":1992,"publication_date":"1992-08-01","ids":{"openalex":"https://openalex.org/W2056528138","doi":"https://doi.org/10.1007/bf00660313","mag":"2056528138","pmid":"https://pubmed.ncbi.nlm.nih.gov/1325896"},"language":"en","primary_location":{"id":"doi:10.1007/bf00660313","doi":"https://doi.org/10.1007/bf00660313","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00660313","pdf_url":null,"source":{"id":"https://openalex.org/S104451582","display_name":"Chromosoma","issn_l":"0009-5915","issn":["0009-5915","1432-0886"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chromosoma","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070889764","display_name":"Brigitta Bienz-Tadmor","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brigitta Bienz-Tadmor","raw_affiliation_strings":["Department of Cellular and Developmental Biology, Harvard University, Cambridge, MA 02138","Department of Cellular and Developmental Biology, The Biological Laboratories, Harvard University, 16 Divinity Avenue, 02138, Cambridge, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular and Developmental Biology, Harvard University, Cambridge, MA 02138","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Cellular and Developmental Biology, The Biological Laboratories, Harvard University, 16 Divinity Avenue, 02138, Cambridge, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024799067","display_name":"Peter P. Tolias","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter Tolias","raw_affiliation_strings":["Department of Cellular and Developmental Biology, The Biological Laboratories, Harvard University, 16 Divinity Avenue, 02138, Cambridge, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular and Developmental Biology, The Biological Laboratories, Harvard University, 16 Divinity Avenue, 02138, Cambridge, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025001928","display_name":"Barbara Stebbins\u2010Boaz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Barbara Stebbins-Boaz","raw_affiliation_strings":["Division of Biology and Medicine, Brown University, 02912, Providence, RI, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biology and Medicine, Brown University, 02912, Providence, RI, USA","institution_ids":["https://openalex.org/I27804330"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071502239","display_name":"Brian D. Mariani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149251103","display_name":"Thomas Jefferson University","ror":"https://ror.org/00ysqcn41","country_code":"US","type":"education","lineage":["https://openalex.org/I149251103"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brian D. Mariani","raw_affiliation_strings":["Jefferson Institution of Molecular Biology, Thomas Jefferson University, 19107, Philadelphia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jefferson Institution of Molecular Biology, Thomas Jefferson University, 19107, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I149251103"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073249685","display_name":"Susan A. Gerbi","orcid":"https://orcid.org/0000-0003-2148-7180","observed_orcids":["https://orcid.org/0000-0003-2148-7180"]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan A. Gerbi","raw_affiliation_strings":["Division of Biology and Medicine, Brown University, 02912, Providence, RI, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biology and Medicine, Brown University, 02912, Providence, RI, USA","institution_ids":["https://openalex.org/I27804330"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111689629","display_name":"Fotis C. Kafatos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210105723","display_name":"FORTH Institute of Molecular Biology and Biotechnology","ror":"https://ror.org/01gzszr18","country_code":"GR","type":"facility","lineage":["https://openalex.org/I4210105723","https://openalex.org/I8901234"]}],"countries":["GR","US"],"is_corresponding":false,"raw_author_name":"Fotis C. Kafatos","raw_affiliation_strings":["Department of Cellular and Developmental Biology, The Biological Laboratories, Harvard University, 16 Divinity Avenue, 02138, Cambridge, MA, USA","Research Center of Crete, Institute of Molecular Biology and Biotechnology, Heraclio 711 10, P.O. Box 1527, Crete, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cellular and Developmental Biology, The Biological Laboratories, Harvard University, 16 Divinity Avenue, 02138, Cambridge, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Research Center of Crete, Institute of Molecular Biology and Biotechnology, Heraclio 711 10, P.O. Box 1527, Crete, Greece","institution_ids":["https://openalex.org/I4210105723"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3890,"currency":"USD","value_usd":3890},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.09942797,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"101","issue":"9","first_page":"538","last_page":"548"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9336000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9336000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.05620000138878822,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/drosophila","display_name":"Drosophila","score":0.7540000081062317},{"id":"https://openalex.org/keywords/tissue-specific-expression","display_name":"tissue-specific gene expression","score":0.628000020980835},{"id":"https://openalex.org/keywords/promoter-regulation","display_name":"promoter regulation","score":0.47699999809265137},{"id":"https://openalex.org/keywords/5-untranslated-region","display_name":"5' untranslated region","score":0.8420000076293945},{"id":"https://openalex.org/keywords/p-element-transformation","display_name":"P-element transformation","score":0.5450000166893005},{"id":"https://openalex.org/keywords/germline-modification","display_name":"germline modification","score":0.8610000014305115},{"id":"https://openalex.org/keywords/chloramphenicol-acetyltransferase","display_name":"chloramphenicol acetyltransferase","score":0.8500000238418579},{"id":"https://openalex.org/keywords/beta-galactosidase","display_name":"beta-galactosidase","score":0.9039999842643738},{"id":"https://openalex.org/keywords/ectopic-expression","display_name":"ectopic expression","score":0.8230000138282776},{"id":"https://openalex.org/keywords/male-genitalia","display_name":"male genitalia","score":0.8320000171661377},{"id":"https://openalex.org/keywords/ovarian-follicles","display_name":"ovarian follicles","score":0.5379999876022339}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8978750705718994},{"id":"https://openalex.org/C161733203","wikidata":"https://www.wikidata.org/wiki/Q911828","display_name":"Reporter gene","level":4,"score":0.7552782893180847},{"id":"https://openalex.org/C2780730277","wikidata":"https://www.wikidata.org/wiki/Q24744759","display_name":"Chloramphenicol acetyltransferase","level":5,"score":0.7248358130455017},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6522632241249084},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.6033643484115601},{"id":"https://openalex.org/C21592294","wikidata":"https://www.wikidata.org/wiki/Q3238407","display_name":"Regulatory sequence","level":4,"score":0.5941159725189209},{"id":"https://openalex.org/C91779695","wikidata":"https://www.wikidata.org/wiki/Q3780824","display_name":"Coding region","level":3,"score":0.5636047720909119},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.5037171244621277},{"id":"https://openalex.org/C97037327","wikidata":"https://www.wikidata.org/wiki/Q5334291","display_name":"Ectopic expression","level":3,"score":0.4999697208404541},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.47778066992759705},{"id":"https://openalex.org/C89604277","wikidata":"https://www.wikidata.org/wiki/Q424345","display_name":"Untranslated region","level":4,"score":0.44542965292930603},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4395008981227875},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.2238607108592987}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001616","descriptor_name":"beta-Galactosidase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002823","descriptor_name":"Chorion","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004251","descriptor_name":"DNA Transposable Elements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004330","descriptor_name":"Drosophila","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005837","descriptor_name":"Genitalia, Male","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009928","descriptor_name":"Organ Specificity","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010053","descriptor_name":"Ovary","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012045","descriptor_name":"Regulatory Sequences, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014170","descriptor_name":"Transformation, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015500","descriptor_name":"Chloramphenicol O-Acetyltransferase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/bf00660313","doi":"https://doi.org/10.1007/bf00660313","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00660313","pdf_url":null,"source":{"id":"https://openalex.org/S104451582","display_name":"Chromosoma","issn_l":"0009-5915","issn":["0009-5915","1432-0886"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chromosoma","raw_type":"journal-article"},{"id":"pmid:1325896","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1325896","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chromosoma","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2009056625","display_name":"Gene Amplification-Sciarid DNA Puffs","funder_award_id":"R01GM035929","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W115258391","https://openalex.org/W262410936","https://openalex.org/W1524737218","https://openalex.org/W1545962441","https://openalex.org/W1940629110","https://openalex.org/W1947528035","https://openalex.org/W1950691615","https://openalex.org/W1972042181","https://openalex.org/W1980589982","https://openalex.org/W1982419880","https://openalex.org/W1988612397","https://openalex.org/W1989322815","https://openalex.org/W1990575544","https://openalex.org/W1994528729","https://openalex.org/W1998966102","https://openalex.org/W2009673759","https://openalex.org/W2010641961","https://openalex.org/W2012880858","https://openalex.org/W2014700650","https://openalex.org/W2018184392","https://openalex.org/W2026548183","https://openalex.org/W2032105273","https://openalex.org/W2044539033","https://openalex.org/W2048321483","https://openalex.org/W2079729858","https://openalex.org/W2080024031","https://openalex.org/W2080269085","https://openalex.org/W2102163061","https://openalex.org/W2103080800","https://openalex.org/W2105442665","https://openalex.org/W2142089685","https://openalex.org/W2150726870","https://openalex.org/W2179328823","https://openalex.org/W2189084452","https://openalex.org/W2269048888","https://openalex.org/W2317639367","https://openalex.org/W4236498790"],"related_works":["https://openalex.org/W2010641961","https://openalex.org/W2102163061","https://openalex.org/W262410936","https://openalex.org/W4323248224","https://openalex.org/W2037704194","https://openalex.org/W1988612397","https://openalex.org/W2063947273","https://openalex.org/W1970113438","https://openalex.org/W1950691615","https://openalex.org/W1976183531"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}