{"id":"https://openalex.org/W2056504792","doi":"https://doi.org/10.1007/s00345-003-0356-x","title":"Radiation therapy dose escalation for prostate cancer: a rationale for IMRT","display_name":"Radiation therapy dose escalation for prostate cancer: a rationale for IMRT","publication_year":2003,"publication_date":"2003-09-01","ids":{"openalex":"https://openalex.org/W2056504792","doi":"https://doi.org/10.1007/s00345-003-0356-x","mag":"2056504792","pmid":"https://pubmed.ncbi.nlm.nih.gov/12961097"},"language":"en","primary_location":{"id":"doi:10.1007/s00345-003-0356-x","doi":"https://doi.org/10.1007/s00345-003-0356-x","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00345-003-0356-x","pdf_url":null,"source":{"id":"https://openalex.org/S49004918","display_name":"World Journal of Urology","issn_l":"0724-4983","issn":["0724-4983","1433-8726"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Urology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063389942","display_name":"Alan S Pollack","orcid":"https://orcid.org/0000-0002-1801-2865","observed_orcids":["https://orcid.org/0000-0002-1801-2865"]},"institutions":[{"id":"https://openalex.org/I1289437631","display_name":"Fox Chase Cancer Center","ror":"https://ror.org/0567t7073","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1289437631","https://openalex.org/I4210122924"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Alan Pollack","raw_affiliation_strings":["Department of Radiation Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA. A_Pollack@fccc.edu","Fox Chase Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA. A_Pollack@fccc.edu","institution_ids":["https://openalex.org/I1289437631"]},{"raw_affiliation_string":"Fox Chase Cancer Center","institution_ids":["https://openalex.org/I1289437631"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109151680","display_name":"Alex L. Hanlon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1289437631","display_name":"Fox Chase Cancer Center","ror":"https://ror.org/0567t7073","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1289437631","https://openalex.org/I4210122924"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alex Hanlon","raw_affiliation_strings":["Department of Biostatistics, Fox Chase Cancer Center, Philadelphia, PA, USA","Fox Chase Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, Fox Chase Cancer Center, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I1289437631"]},{"raw_affiliation_string":"Fox Chase Cancer Center","institution_ids":["https://openalex.org/I1289437631"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103691037","display_name":"Eric M. Horwitz","orcid":"https://orcid.org/0000-0003-2187-317X","observed_orcids":["https://orcid.org/0000-0003-2187-317X"]},"institutions":[{"id":"https://openalex.org/I1289437631","display_name":"Fox Chase Cancer Center","ror":"https://ror.org/0567t7073","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1289437631","https://openalex.org/I4210122924"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric M. Horwitz","raw_affiliation_strings":["Department of Radiation Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA","Fox Chase Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA","institution_ids":["https://openalex.org/I1289437631"]},{"raw_affiliation_string":"Fox Chase Cancer Center","institution_ids":["https://openalex.org/I1289437631"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035208282","display_name":"Steven Joel Feigenberg","orcid":"https://orcid.org/0000-0001-6179-0040","observed_orcids":["https://orcid.org/0000-0001-6179-0040"]},"institutions":[{"id":"https://openalex.org/I1289437631","display_name":"Fox Chase Cancer Center","ror":"https://ror.org/0567t7073","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1289437631","https://openalex.org/I4210122924"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven Feigenberg","raw_affiliation_strings":["Department of Radiation Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA","Fox Chase Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA","institution_ids":["https://openalex.org/I1289437631"]},{"raw_affiliation_string":"Fox Chase Cancer Center","institution_ids":["https://openalex.org/I1289437631"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043554307","display_name":"Robert G. Uzzo","orcid":"https://orcid.org/0000-0003-2398-6530","observed_orcids":["https://orcid.org/0000-0003-2398-6530"]},"institutions":[{"id":"https://openalex.org/I1289437631","display_name":"Fox Chase Cancer Center","ror":"https://ror.org/0567t7073","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1289437631","https://openalex.org/I4210122924"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert G. Uzzo","raw_affiliation_strings":["Department of Urology, Fox Chase Cancer Center, Philadelphia, PA, USA","Fox Chase Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Fox Chase Cancer Center, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I1289437631"]},{"raw_affiliation_string":"Fox Chase Cancer Center","institution_ids":["https://openalex.org/I1289437631"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060104637","display_name":"R Price","orcid":"https://orcid.org/0000-0003-1177-5699","observed_orcids":["https://orcid.org/0000-0003-1177-5699"]},"institutions":[{"id":"https://openalex.org/I1289437631","display_name":"Fox Chase Cancer Center","ror":"https://ror.org/0567t7073","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1289437631","https://openalex.org/I4210122924"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert A. Price","raw_affiliation_strings":["Department of Radiation Physics, Fox Chase Cancer Center, Philadelphia, PA, USA","Fox Chase Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Physics, Fox Chase Cancer Center, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I1289437631"]},{"raw_affiliation_string":"Fox Chase Cancer Center","institution_ids":["https://openalex.org/I1289437631"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5063389942"],"corresponding_institution_ids":["https://openalex.org/I1289437631"],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":6.1929,"has_fulltext":false,"cited_by_count":79,"citation_normalized_percentile":{"value":0.96604722,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"21","issue":"4","first_page":"200","last_page":"208"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.6615999937057495,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.6615999937057495,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.33500000834465027,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.996999979019165},{"id":"https://openalex.org/keywords/radiotherapy-dose-escalation","display_name":"radiation dose escalation","score":0.8740000128746033},{"id":"https://openalex.org/keywords/intensity-modulated-radiotherapy","display_name":"intensity-modulated radiotherapy","score":0.9259999990463257},{"id":"https://openalex.org/keywords/three-dimensional-conformal-radiotherapy","display_name":"3D conformal radiotherapy","score":0.8519999980926514},{"id":"https://openalex.org/keywords/biochemical-recurrence","display_name":"biochemical recurrence","score":0.8840000033378601},{"id":"https://openalex.org/keywords/rectal-toxicity","display_name":"rectal toxicity","score":0.8700000047683716},{"id":"https://openalex.org/keywords/bladder-toxicity","display_name":"bladder toxicity","score":0.9919999837875366},{"id":"https://openalex.org/keywords/normal-tissue-sparing","display_name":"normal tissue sparing","score":0.8640000224113464},{"id":"https://openalex.org/keywords/prostate-imaging","display_name":"prostate imaging","score":0.4189999997615814}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9482822418212891},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.8148518204689026},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.7252827882766724},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.6311883330345154},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.5023980140686035},{"id":"https://openalex.org/C203092338","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Clinical endpoint","level":3,"score":0.45405322313308716},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.36240512132644653},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.35766416788101196},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3562760353088379},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.34110695123672485},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.33505162596702576},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.32976025342941284}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D011878","descriptor_name":"Radiotherapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D011879","descriptor_name":"Radiotherapy Dosage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s00345-003-0356-x","doi":"https://doi.org/10.1007/s00345-003-0356-x","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00345-003-0356-x","pdf_url":null,"source":{"id":"https://openalex.org/S49004918","display_name":"World Journal of Urology","issn_l":"0724-4983","issn":["0724-4983","1433-8726"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Urology","raw_type":"journal-article"},{"id":"pmid:12961097","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12961097","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World journal of urology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":73,"referenced_works":["https://openalex.org/W30738240","https://openalex.org/W1894827484","https://openalex.org/W1964702836","https://openalex.org/W1976578751","https://openalex.org/W1979914233","https://openalex.org/W1984994876","https://openalex.org/W1986019734","https://openalex.org/W1987345862","https://openalex.org/W1988841675","https://openalex.org/W1989542568","https://openalex.org/W1990510898","https://openalex.org/W1991432796","https://openalex.org/W1996422254","https://openalex.org/W1996550652","https://openalex.org/W2006081762","https://openalex.org/W2006333174","https://openalex.org/W2010109601","https://openalex.org/W2016557692","https://openalex.org/W2022266950","https://openalex.org/W2023807811","https://openalex.org/W2024413350","https://openalex.org/W2024817951","https://openalex.org/W2025895255","https://openalex.org/W2037920341","https://openalex.org/W2046627726","https://openalex.org/W2056643793","https://openalex.org/W2056903679","https://openalex.org/W2059702431","https://openalex.org/W2061729318","https://openalex.org/W2062531523","https://openalex.org/W2063960686","https://openalex.org/W2065184437","https://openalex.org/W2068115015","https://openalex.org/W2071238711","https://openalex.org/W2072063669","https://openalex.org/W2079190531","https://openalex.org/W2081239061","https://openalex.org/W2084269392","https://openalex.org/W2088122634","https://openalex.org/W2089403922","https://openalex.org/W2089724191","https://openalex.org/W2091780056","https://openalex.org/W2093485750","https://openalex.org/W2093611285","https://openalex.org/W2094528839","https://openalex.org/W2095229531","https://openalex.org/W2096700379","https://openalex.org/W2097860252","https://openalex.org/W2099288242","https://openalex.org/W2103429819","https://openalex.org/W2104631398","https://openalex.org/W2108773718","https://openalex.org/W2109406868","https://openalex.org/W2112095335","https://openalex.org/W2114251516","https://openalex.org/W2117792530","https://openalex.org/W2130514725","https://openalex.org/W2140813067","https://openalex.org/W2146421906","https://openalex.org/W2146777557","https://openalex.org/W2150373135","https://openalex.org/W2152171586","https://openalex.org/W2153674426","https://openalex.org/W2153685427","https://openalex.org/W2157797729","https://openalex.org/W2159813118","https://openalex.org/W2161749968","https://openalex.org/W2163217542","https://openalex.org/W2171210159","https://openalex.org/W2329611551","https://openalex.org/W2407499258","https://openalex.org/W2408947935","https://openalex.org/W2440304984"],"related_works":["https://openalex.org/W1964319988","https://openalex.org/W2781713704","https://openalex.org/W2153893052","https://openalex.org/W2210807920","https://openalex.org/W2029240181","https://openalex.org/W2007447043","https://openalex.org/W2153436426","https://openalex.org/W2107475609","https://openalex.org/W2068947755","https://openalex.org/W4237479172"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
