{"id":"https://openalex.org/W2055935569","doi":"https://doi.org/10.1097/00001648-200107000-00014","title":"Maternal Prepregnancy Weight and Congenital Heart Defects in the Offspring","display_name":"Maternal Prepregnancy Weight and Congenital Heart Defects in the Offspring","publication_year":2001,"publication_date":"2001-07-01","ids":{"openalex":"https://openalex.org/W2055935569","doi":"https://doi.org/10.1097/00001648-200107000-00014","mag":"2055935569","pmid":"https://pubmed.ncbi.nlm.nih.gov/11416768"},"language":"en","primary_location":{"id":"doi:10.1097/00001648-200107000-00014","doi":"https://doi.org/10.1097/00001648-200107000-00014","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00001648-200107000-00014","pdf_url":null,"source":{"id":"https://openalex.org/S15470582","display_name":"Epidemiology","issn_l":"1044-3983","issn":["1044-3983","1531-5487"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epidemiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103541134","display_name":"Margaret L. Watkins","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]},{"id":"https://openalex.org/I4210092468","display_name":"National Center for Environmental Health","ror":"https://ror.org/00jc2kw33","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934","https://openalex.org/I4210092468"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Margaret L. Watkins","raw_affiliation_strings":["Margaret Watkins, Birth Defects and Pediatric Genetics Branch, MS F-45, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Atlanta, GA 30341-3724","the Birth Defects and Pediatric Genetics Branch, Division of Birth Defects, Child Development, Disability and Health, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Margaret Watkins, Birth Defects and Pediatric Genetics Branch, MS F-45, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Atlanta, GA 30341-3724","institution_ids":["https://openalex.org/I1289490764"]},{"raw_affiliation_string":"the Birth Defects and Pediatric Genetics Branch, Division of Birth Defects, Child Development, Disability and Health, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA","institution_ids":["https://openalex.org/I1289490764","https://openalex.org/I4210092468"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043230326","display_name":"Lorenzo D. Botto","orcid":"https://orcid.org/0000-0002-5322-7116","observed_orcids":["https://orcid.org/0000-0002-5322-7116"]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]},{"id":"https://openalex.org/I4210092468","display_name":"National Center for Environmental Health","ror":"https://ror.org/00jc2kw33","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934","https://openalex.org/I4210092468"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lorenzo D. Botto","raw_affiliation_strings":["the Birth Defects and Pediatric Genetics Branch, Division of Birth Defects, Child Development, Disability and Health, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Birth Defects and Pediatric Genetics Branch, Division of Birth Defects, Child Development, Disability and Health, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA","institution_ids":["https://openalex.org/I1289490764","https://openalex.org/I4210092468"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.2552,"has_fulltext":false,"cited_by_count":109,"citation_normalized_percentile":{"value":0.94350975,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"12","issue":"4","first_page":"439","last_page":"446"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10300","display_name":"Congenital Heart Disease Studies","score":0.24009999632835388,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10300","display_name":"Congenital Heart Disease Studies","score":0.24009999632835388,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":0.22689999639987946,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11677","display_name":"Congenital heart defects research","score":0.1136000007390976,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/congenital-heart-disease","display_name":"congenital heart disease","score":0.8429999947547913},{"id":"https://openalex.org/keywords/pre-pregnancy-weight","display_name":"pre-pregnancy weight","score":0.8240000009536743},{"id":"https://openalex.org/keywords/maternal-obesity","display_name":"maternal obesity","score":0.8140000104904175},{"id":"https://openalex.org/keywords/maternal-underweight","display_name":"maternal underweight","score":0.9610000252723694},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.8399999737739563},{"id":"https://openalex.org/keywords/prenatal-nutrition","display_name":"prenatal nutrition","score":0.35199999809265137},{"id":"https://openalex.org/keywords/congenital-malformations","display_name":"congenital malformations","score":0.4650000035762787},{"id":"https://openalex.org/keywords/maternal-weight","display_name":"maternal weight","score":0.34700000286102295}],"concepts":[{"id":"https://openalex.org/C2781121325","wikidata":"https://www.wikidata.org/wiki/Q1146902","display_name":"Underweight","level":4,"score":0.8500027656555176},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8229027986526489},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.7371136546134949},{"id":"https://openalex.org/C2780586474","wikidata":"https://www.wikidata.org/wiki/Q332428","display_name":"Overweight","level":3,"score":0.7351983189582825},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.6171882152557373},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.5746728777885437},{"id":"https://openalex.org/C66322754","wikidata":"https://www.wikidata.org/wiki/Q4128476","display_name":"Birth weight","level":3,"score":0.5538218021392822},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.507644534111023},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.47838202118873596},{"id":"https://openalex.org/C2779083892","wikidata":"https://www.wikidata.org/wiki/Q6692979","display_name":"Low birth weight","level":3,"score":0.4471844434738159},{"id":"https://openalex.org/C2776551950","wikidata":"https://www.wikidata.org/wiki/Q172395","display_name":"Multivitamin","level":3,"score":0.42028912901878357},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.4092055857181549},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15361595153808594},{"id":"https://openalex.org/C2776940978","wikidata":"https://www.wikidata.org/wiki/Q34956","display_name":"Vitamin","level":2,"score":0.04231405258178711},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1097/00001648-200107000-00014","doi":"https://doi.org/10.1097/00001648-200107000-00014","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00001648-200107000-00014","pdf_url":null,"source":{"id":"https://openalex.org/S15470582","display_name":"Epidemiology","issn_l":"1044-3983","issn":["1044-3983","1531-5487"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epidemiology","raw_type":"journal-article"},{"id":"pmid:11416768","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11416768","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epidemiology (Cambridge, Mass.)","raw_type":"Journal Article"},{"id":"pmid:11428386","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11428386","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epidemiology (Cambridge, Mass.)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W167509644","https://openalex.org/W174305235","https://openalex.org/W1992708416","https://openalex.org/W1995676272","https://openalex.org/W1997232458","https://openalex.org/W2000762831","https://openalex.org/W2001107260","https://openalex.org/W2005190933","https://openalex.org/W2013274050","https://openalex.org/W2023744589","https://openalex.org/W2046951457","https://openalex.org/W2050359523","https://openalex.org/W2059840060","https://openalex.org/W2067001734","https://openalex.org/W2088825782","https://openalex.org/W2089746931","https://openalex.org/W2099871691","https://openalex.org/W2112036987","https://openalex.org/W2118129724","https://openalex.org/W2314887151","https://openalex.org/W2397833095","https://openalex.org/W4232005525","https://openalex.org/W4235676428","https://openalex.org/W4298190266"],"related_works":["https://openalex.org/W2145889125","https://openalex.org/W7014416823","https://openalex.org/W3047152845","https://openalex.org/W1602851854","https://openalex.org/W2101525058","https://openalex.org/W2055159612","https://openalex.org/W2909413406","https://openalex.org/W4400786486","https://openalex.org/W4394873605","https://openalex.org/W2032710223"],"abstract_inverted_index":{"To":[0],"determine":[1],"the":[2,64,129,159],"relation":[3],"between":[4],"having":[5],"an":[6],"infant":[7],"with":[8,32,37,88,111,167],"a":[9,14,33,109,112,168],"major":[10,34,113],"heart":[11,35,115,173],"defect":[12,116],"and":[13,60,71,82,185],"mother's":[15],"prepregnancy":[16],"weight,":[17],"we":[18,95],"compared":[19,87],"1,049":[20],"Atlanta-area":[21,39],"women":[22,40,53,90,99,137,151,177,187,194],"who":[23,41,152],"gave":[24,42],"birth":[25,43,47,58,69,72],"to":[26,44,63,107],"liveborn":[27],"or":[28,135,192],"stillborn":[29],"infants,":[30],"each":[31],"defect,":[36],"3,029":[38],"infants":[45,50],"without":[46],"defects.":[48],"The":[49],"of":[51],"control":[52],"were":[54,61,104],"randomly":[55],"selected":[56],"from":[57,74],"certificates":[59],"frequency-matched":[62],"case":[65],"group":[66],"by":[67],"race,":[68],"hospital,":[70],"period":[73],"1968":[75],"through":[76],"1980.":[77],"After":[78],"excluding":[79],"diabetic":[80],"mothers":[81],"adjusting":[83],"for":[84,171],"potential":[85],"confounders,":[86],"average-weight":[89,150,176],"(body":[91,100,138],"mass":[92,101,139],"index":[93,102,140],"19.9--22.7),":[94],"found":[96],"that":[97],"underweight":[98,186],"<16.5)":[103],"less":[105],"likely":[106],"have":[108],"child":[110],"isolated":[114,172],"[odds":[117],"ratio":[118],"(OR)":[119],"=":[120,126,143,147,179,183,196,200],"0.64;":[121],"95%":[122,145,181,198],"confidence":[123],"interval":[124],"(CI)":[125],"0.43--0.97],":[127],"whereas":[128],"OR":[130,170],"was":[131,165],"elevated":[132],"among":[133,175,190],"overweight":[134,191],"obese":[136,193],">26)":[141],"(OR":[142,178,195],"1.36;":[144],"CI":[146,182,199],"0.95--1.93).":[148],"Using":[149],"did":[153],"not":[154,189],"take":[155],"periconceptional":[156,162],"multivitamins":[157],"as":[158],"reference":[160],"group,":[161],"multivitamin":[163],"use":[164],"associated":[166],"reduced":[169],"defects":[174],"0.61,":[180],"0.36--0.99)":[184],"but":[188],"1.69,":[197],"0.69--3.84).":[201]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":8}],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2016-06-24T00:00:00"}