{"id":"https://openalex.org/W2055830753","doi":"https://doi.org/10.1016/j.arr.2014.11.001","title":"Sleep disorders, obesity, and aging: The role of orexin","display_name":"Sleep disorders, obesity, and aging: The role of orexin","publication_year":2014,"publication_date":"2014-11-22","ids":{"openalex":"https://openalex.org/W2055830753","doi":"https://doi.org/10.1016/j.arr.2014.11.001","mag":"2055830753","pmid":"https://pubmed.ncbi.nlm.nih.gov/25462194","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4467809"},"language":"en","primary_location":{"id":"doi:10.1016/j.arr.2014.11.001","doi":"https://doi.org/10.1016/j.arr.2014.11.001","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.arr.2014.11.001","pdf_url":null,"source":{"id":"https://openalex.org/S117312820","display_name":"Ageing Research Reviews","issn_l":"1568-1637","issn":["1568-1637","1872-9649"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ageing Research Reviews","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4467809","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083646784","display_name":"Joshua P. Nixon","orcid":"https://orcid.org/0000-0003-0181-2767","observed_orcids":["https://orcid.org/0000-0003-0181-2767"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I4210117246","display_name":"Minneapolis VA Health Care System","ror":"https://ror.org/02ry60714","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210117246","https://openalex.org/I4210117924"]},{"id":"https://openalex.org/I4210140408","display_name":"Minneapolis VA Medical Center","ror":"https://ror.org/032b8d361","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210117246","https://openalex.org/I4210117924","https://openalex.org/I4210140408"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joshua P. Nixon","raw_affiliation_strings":["Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA; Minnesota Obesity Center, 1334 Eckles Avenue, Saint Paul, MN 55108, USA; University of Minnesota, Department of Food Science and Nutrition, 1334 Eckles Avenue, Saint Paul, MN 55108, USA. Electronic address: nixon049@umn.edu","Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA","Minnesota Obesity Center, 1334 Eckles Avenue, Saint Paul, MN 55108, USA","University of Minnesota, Department of Food Science and Nutrition, 1334 Eckles Avenue, Saint Paul, MN 55108, USA"],"raw_orcid":"https://orcid.org/0000-0003-0181-2767","affiliations":[{"raw_affiliation_string":"Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA; Minnesota Obesity Center, 1334 Eckles Avenue, Saint Paul, MN 55108, USA; University of Minnesota, Department of Food Science and Nutrition, 1334 Eckles Avenue, Saint Paul, MN 55108, USA. Electronic address: nixon049@umn.edu","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4210117246","https://openalex.org/I4210140408"]},{"raw_affiliation_string":"Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA","institution_ids":["https://openalex.org/I4210117246"]},{"raw_affiliation_string":"Minnesota Obesity Center, 1334 Eckles Avenue, Saint Paul, MN 55108, USA","institution_ids":[]},{"raw_affiliation_string":"University of Minnesota, Department of Food Science and Nutrition, 1334 Eckles Avenue, Saint Paul, MN 55108, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025968018","display_name":"Vijayakumar Mavanji","orcid":"https://orcid.org/0000-0001-8032-2242","observed_orcids":["https://orcid.org/0000-0001-8032-2242"]},"institutions":[{"id":"https://openalex.org/I4210117246","display_name":"Minneapolis VA Health Care System","ror":"https://ror.org/02ry60714","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210117246","https://openalex.org/I4210117924"]},{"id":"https://openalex.org/I4210140408","display_name":"Minneapolis VA Medical Center","ror":"https://ror.org/032b8d361","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210117246","https://openalex.org/I4210117924","https://openalex.org/I4210140408"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vijayakumar Mavanji","raw_affiliation_strings":["Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA. Electronic address: mavan001@umn.edu","Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA. Electronic address: mavan001@umn.edu","institution_ids":["https://openalex.org/I4210117246","https://openalex.org/I4210140408"]},{"raw_affiliation_string":"Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA","institution_ids":["https://openalex.org/I4210117246"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055197234","display_name":"Tammy A. Butterick","orcid":"https://orcid.org/0000-0001-8516-0385","observed_orcids":["https://orcid.org/0000-0001-8516-0385"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I4210117246","display_name":"Minneapolis VA Health Care System","ror":"https://ror.org/02ry60714","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210117246","https://openalex.org/I4210117924"]},{"id":"https://openalex.org/I4210140408","display_name":"Minneapolis VA Medical Center","ror":"https://ror.org/032b8d361","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210117246","https://openalex.org/I4210117924","https://openalex.org/I4210140408"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tammy A. Butterick","raw_affiliation_strings":["Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA; University of Minnesota, Department of Food Science and Nutrition, 1334 Eckles Avenue, Saint Paul, MN 55108, USA. Electronic address: butte017@umn.edu","Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA","University of Minnesota, Department of Food Science and Nutrition, 1334 Eckles Avenue, Saint Paul, MN 55108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA; University of Minnesota, Department of Food Science and Nutrition, 1334 Eckles Avenue, Saint Paul, MN 55108, USA. Electronic address: butte017@umn.edu","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4210117246","https://openalex.org/I4210140408"]},{"raw_affiliation_string":"Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA","institution_ids":["https://openalex.org/I4210117246"]},{"raw_affiliation_string":"University of Minnesota, Department of Food Science and Nutrition, 1334 Eckles Avenue, Saint Paul, MN 55108, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090515985","display_name":"Charles John Billington","orcid":"https://orcid.org/0000-0002-9826-1860","observed_orcids":["https://orcid.org/0000-0002-9826-1860"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I4210117246","display_name":"Minneapolis VA Health Care System","ror":"https://ror.org/02ry60714","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210117246","https://openalex.org/I4210117924"]},{"id":"https://openalex.org/I4210140408","display_name":"Minneapolis VA Medical Center","ror":"https://ror.org/032b8d361","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210117246","https://openalex.org/I4210117924","https://openalex.org/I4210140408"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles J. Billington","raw_affiliation_strings":["Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA; Department of Medicine, University of Minnesota, 420 Delaware Street SE, Minneapolis, MN 55455, USA; Minnesota Obesity Center, 1334 Eckles Avenue, Saint Paul, MN 55108, USA; University of Minnesota, Department of Food Science and Nutrition, 1334 Eckles Avenue, Saint Paul, MN 55108, USA. Electronic address: billi005@umn.edu","Department of Medicine, University of Minnesota, 420 Delaware Street SE, Minneapolis, MN 55455, USA","Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA","Minnesota Obesity Center, 1334 Eckles Avenue, Saint Paul, MN 55108, USA","University of Minnesota, Department of Food Science and Nutrition, 1334 Eckles Avenue, Saint Paul, MN 55108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA; Department of Medicine, University of Minnesota, 420 Delaware Street SE, Minneapolis, MN 55455, USA; Minnesota Obesity Center, 1334 Eckles Avenue, Saint Paul, MN 55108, USA; University of Minnesota, Department of Food Science and Nutrition, 1334 Eckles Avenue, Saint Paul, MN 55108, USA. Electronic address: billi005@umn.edu","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4210117246","https://openalex.org/I4210140408"]},{"raw_affiliation_string":"Department of Medicine, University of Minnesota, 420 Delaware Street SE, Minneapolis, MN 55455, USA","institution_ids":["https://openalex.org/I130238516"]},{"raw_affiliation_string":"Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA","institution_ids":["https://openalex.org/I4210117246"]},{"raw_affiliation_string":"Minnesota Obesity Center, 1334 Eckles Avenue, Saint Paul, MN 55108, USA","institution_ids":[]},{"raw_affiliation_string":"University of Minnesota, Department of Food Science and Nutrition, 1334 Eckles Avenue, Saint Paul, MN 55108, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075859897","display_name":"Catherine M. Kotz","orcid":"https://orcid.org/0000-0003-0051-3159","observed_orcids":["https://orcid.org/0000-0003-0051-3159"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I4210117246","display_name":"Minneapolis VA Health Care System","ror":"https://ror.org/02ry60714","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210117246","https://openalex.org/I4210117924"]},{"id":"https://openalex.org/I4210140408","display_name":"Minneapolis VA Medical Center","ror":"https://ror.org/032b8d361","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210117246","https://openalex.org/I4210117924","https://openalex.org/I4210140408"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Catherine M. Kotz","raw_affiliation_strings":["Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA; Geriatric Research Education and Clinical Center, One Veterans Drive, Minneapolis, MN 55417, USA; Minnesota Obesity Center, 1334 Eckles Avenue, Saint Paul, MN 55108, USA; University of Minnesota, Department of Food Science and Nutrition, 1334 Eckles Avenue, Saint Paul, MN 55108, USA. Electronic address: kotzx004@umn.edu","Geriatric Research Education and Clinical Center, One Veterans Drive, Minneapolis, MN 55417, USA","Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA","Minnesota Obesity Center, 1334 Eckles Avenue, Saint Paul, MN 55108, USA","University of Minnesota, Department of Food Science and Nutrition, 1334 Eckles Avenue, Saint Paul, MN 55108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA; Geriatric Research Education and Clinical Center, One Veterans Drive, Minneapolis, MN 55417, USA; Minnesota Obesity Center, 1334 Eckles Avenue, Saint Paul, MN 55108, USA; University of Minnesota, Department of Food Science and Nutrition, 1334 Eckles Avenue, Saint Paul, MN 55108, USA. Electronic address: kotzx004@umn.edu","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4210117246","https://openalex.org/I4210140408"]},{"raw_affiliation_string":"Geriatric Research Education and Clinical Center, One Veterans Drive, Minneapolis, MN 55417, USA","institution_ids":[]},{"raw_affiliation_string":"Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA","institution_ids":["https://openalex.org/I4210117246"]},{"raw_affiliation_string":"Minnesota Obesity Center, 1334 Eckles Avenue, Saint Paul, MN 55108, USA","institution_ids":[]},{"raw_affiliation_string":"University of Minnesota, Department of Food Science and Nutrition, 1334 Eckles Avenue, Saint Paul, MN 55108, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062337581","display_name":"Jennifer A. Teske","orcid":"https://orcid.org/0000-0003-4051-6602","observed_orcids":["https://orcid.org/0000-0003-4051-6602"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I138006243","display_name":"University of Arizona","ror":"https://ror.org/03m2x1q45","country_code":"US","type":"education","lineage":["https://openalex.org/I138006243"]},{"id":"https://openalex.org/I4210117246","display_name":"Minneapolis VA Health Care System","ror":"https://ror.org/02ry60714","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210117246","https://openalex.org/I4210117924"]},{"id":"https://openalex.org/I4210140408","display_name":"Minneapolis VA Medical Center","ror":"https://ror.org/032b8d361","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210117246","https://openalex.org/I4210117924","https://openalex.org/I4210140408"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jennifer A. Teske","raw_affiliation_strings":["Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA; Minnesota Obesity Center, 1334 Eckles Avenue, Saint Paul, MN 55108, USA; University of Minnesota, Department of Food Science and Nutrition, 1334 Eckles Avenue, Saint Paul, MN 55108, USA; University of Arizona, Department of Nutritional Sciences, 1177 East 4th Street, Shantz Building #332, Tucson, AZ, USA. Electronic address: teskeja@email.arizona.edu","Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA","Minnesota Obesity Center, 1334 Eckles Avenue, Saint Paul, MN 55108, USA","University of Arizona, Department of Nutritional Sciences, 1177 East 4th Street, Shantz Building #332, Tucson, AZ, USA","University of Minnesota, Department of Food Science and Nutrition, 1334 Eckles Avenue, Saint Paul, MN 55108, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA; Minnesota Obesity Center, 1334 Eckles Avenue, Saint Paul, MN 55108, USA; University of Minnesota, Department of Food Science and Nutrition, 1334 Eckles Avenue, Saint Paul, MN 55108, USA; University of Arizona, Department of Nutritional Sciences, 1177 East 4th Street, Shantz Building #332, Tucson, AZ, USA. Electronic address: teskeja@email.arizona.edu","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I138006243","https://openalex.org/I4210117246","https://openalex.org/I4210140408"]},{"raw_affiliation_string":"Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA","institution_ids":["https://openalex.org/I4210117246"]},{"raw_affiliation_string":"Minnesota Obesity Center, 1334 Eckles Avenue, Saint Paul, MN 55108, USA","institution_ids":[]},{"raw_affiliation_string":"University of Arizona, Department of Nutritional Sciences, 1177 East 4th Street, Shantz Building #332, Tucson, AZ, USA","institution_ids":["https://openalex.org/I138006243"]},{"raw_affiliation_string":"University of Minnesota, Department of Food Science and Nutrition, 1334 Eckles Avenue, Saint Paul, MN 55108, USA","institution_ids":["https://openalex.org/I130238516"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5062337581"],"corresponding_institution_ids":["https://openalex.org/I130238516","https://openalex.org/I138006243","https://openalex.org/I4210117246","https://openalex.org/I4210140408"],"apc_list":{"value":5520,"currency":"USD","value_usd":5520},"apc_paid":null,"fwci":1.0557,"has_fulltext":false,"cited_by_count":133,"citation_normalized_percentile":{"value":0.71903751,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"20","issue":null,"first_page":"63","last_page":"73"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/orexin","display_name":"orexin","score":0.9909999966621399},{"id":"https://openalex.org/keywords/sleep-disturbance","display_name":"sleep disorders","score":0.8690000176429749},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.9779999852180481},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.996999979019165},{"id":"https://openalex.org/keywords/energy-balance","display_name":"energy balance","score":0.8610000014305115},{"id":"https://openalex.org/keywords/narcolepsy","display_name":"narcolepsy","score":0.9789999723434448},{"id":"https://openalex.org/keywords/insomnia","display_name":"insomnia","score":0.9869999885559082},{"id":"https://openalex.org/keywords/age-related-cognitive-decline","display_name":"age-related cognitive decline","score":0.890999972820282},{"id":"https://openalex.org/keywords/neurodegenerative-diseases","display_name":"neurodegenerative diseases","score":0.968999981880188},{"id":"https://openalex.org/keywords/orexin-receptor-agonists","display_name":"orexin receptor agonists","score":0.8740000128746033},{"id":"https://openalex.org/keywords/sleep-homeostasis","display_name":"sleep homeostasis","score":0.7089999914169312}],"concepts":[{"id":"https://openalex.org/C2779680196","wikidata":"https://www.wikidata.org/wiki/Q410857","display_name":"Orexin","level":4,"score":0.942003071308136},{"id":"https://openalex.org/C2779494582","wikidata":"https://www.wikidata.org/wiki/Q189561","display_name":"Narcolepsy","level":3,"score":0.8875226974487305},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5768992900848389},{"id":"https://openalex.org/C2779605129","wikidata":"https://www.wikidata.org/wiki/Q24785218","display_name":"Orexin receptor","level":5,"score":0.5625407695770264},{"id":"https://openalex.org/C2776119998","wikidata":"https://www.wikidata.org/wiki/Q1070023","display_name":"Orexin-A","level":5,"score":0.56219083070755},{"id":"https://openalex.org/C2491326","wikidata":"https://www.wikidata.org/wiki/Q5377024","display_name":"Energy homeostasis","level":3,"score":0.5224451422691345},{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.424945592880249},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40745267271995544},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39835798740386963},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3849695026874542},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3777623474597931},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3565812110900879},{"id":"https://openalex.org/C118303440","wikidata":"https://www.wikidata.org/wiki/Q419968","display_name":"Neuropeptide","level":3,"score":0.35531318187713623},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.33150556683540344},{"id":"https://openalex.org/C16568411","wikidata":"https://www.wikidata.org/wiki/Q83042","display_name":"Neurology","level":2,"score":0.3248121738433838},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.19698619842529297},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000068797","descriptor_name":"Orexins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006706","descriptor_name":"Homeostasis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007031","descriptor_name":"Hypothalamus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007031","descriptor_name":"Hypothalamus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D009479","descriptor_name":"Neuropeptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009479","descriptor_name":"Neuropeptides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012890","descriptor_name":"Sleep","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012890","descriptor_name":"Sleep","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012893","descriptor_name":"Sleep Wake Disorders","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D012893","descriptor_name":"Sleep Wake Disorders","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018377","descriptor_name":"Neurotransmitter Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018377","descriptor_name":"Neurotransmitter Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D047908","descriptor_name":"Intracellular Signaling Peptides and Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D047908","descriptor_name":"Intracellular Signaling Peptides and Proteins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.arr.2014.11.001","doi":"https://doi.org/10.1016/j.arr.2014.11.001","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.arr.2014.11.001","pdf_url":null,"source":{"id":"https://openalex.org/S117312820","display_name":"Ageing Research Reviews","issn_l":"1568-1637","issn":["1568-1637","1872-9649"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ageing Research Reviews","raw_type":"journal-article"},{"id":"pmid:25462194","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25462194","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ageing research reviews","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4467809","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4467809","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Ageing Res Rev","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4467809","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4467809","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Ageing Res Rev","raw_type":"Text"},"sustainable_development_goals":[{"score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3216050033","display_name":null,"funder_award_id":"IK2 BX001686","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G4205969177","display_name":null,"funder_award_id":"F7212W","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G4398288959","display_name":"Role of Variability in SPA in Susceptibility to Obesity","funder_award_id":"R01DK100281","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G4612284857","display_name":"Enhancing NEAT to Treat Obesity","funder_award_id":"5i01rx000441-04","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G4967938861","display_name":"Orexin Induced Gene and Protein Expression Patterns in the rLH","funder_award_id":"1ik2bx001686-01a1","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G566131683","display_name":null,"funder_award_id":"I01 RX000441","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G5873498492","display_name":null,"funder_award_id":"ARZT-1372540-R23-131","funder_id":"https://openalex.org/F4320306114","funder_display_name":"U.S. Department of Agriculture"},{"id":"https://openalex.org/G874742386","display_name":null,"funder_award_id":"ARZT-1360220-H23-150","funder_id":"https://openalex.org/F4320306114","funder_display_name":"U.S. Department of Agriculture"}],"funders":[{"id":"https://openalex.org/F4320306114","display_name":"U.S. Department of Agriculture","ror":"https://ror.org/01na82s61"},{"id":"https://openalex.org/F4320306127","display_name":"U.S. Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":204,"referenced_works":["https://openalex.org/W26111232","https://openalex.org/W56856045","https://openalex.org/W63759992","https://openalex.org/W88116543","https://openalex.org/W107994996","https://openalex.org/W142147795","https://openalex.org/W265551476","https://openalex.org/W1512329974","https://openalex.org/W1519232679","https://openalex.org/W1566994573","https://openalex.org/W1570515437","https://openalex.org/W1627229807","https://openalex.org/W1820942030","https://openalex.org/W1828412318","https://openalex.org/W1829186012","https://openalex.org/W1878615666","https://openalex.org/W1945000294","https://openalex.org/W1956388950","https://openalex.org/W1965147820","https://openalex.org/W1966535416","https://openalex.org/W1967884630","https://openalex.org/W1968914473","https://openalex.org/W1968974329","https://openalex.org/W1969290948","https://openalex.org/W1970530799","https://openalex.org/W1972824008","https://openalex.org/W1973557838","https://openalex.org/W1977320288","https://openalex.org/W1978468194","https://openalex.org/W1979133711","https://openalex.org/W1979136504","https://openalex.org/W1979925785","https://openalex.org/W1983298714","https://openalex.org/W1983445020","https://openalex.org/W1986545656","https://openalex.org/W1988065740","https://openalex.org/W1990388529","https://openalex.org/W1992357520","https://openalex.org/W1992534520","https://openalex.org/W1992895646","https://openalex.org/W1996872134","https://openalex.org/W1997860957","https://openalex.org/W1999331745","https://openalex.org/W2000555736","https://openalex.org/W2000778212","https://openalex.org/W2005234272","https://openalex.org/W2005859601","https://openalex.org/W2006261899","https://openalex.org/W2006884518","https://openalex.org/W2008847342","https://openalex.org/W2010158447","https://openalex.org/W2010200492","https://openalex.org/W2010273083","https://openalex.org/W2010417274","https://openalex.org/W2013333500","https://openalex.org/W2013655437","https://openalex.org/W2014031369","https://openalex.org/W2014512264","https://openalex.org/W2016603747","https://openalex.org/W2018733537","https://openalex.org/W2018744564","https://openalex.org/W2019174868","https://openalex.org/W2022653093","https://openalex.org/W2022687465","https://openalex.org/W2023425789","https://openalex.org/W2023850950","https://openalex.org/W2024183517","https://openalex.org/W2024539870","https://openalex.org/W2024830095","https://openalex.org/W2025705478","https://openalex.org/W2026283819","https://openalex.org/W2026441563","https://openalex.org/W2026844628","https://openalex.org/W2027740042","https://openalex.org/W2027838133","https://openalex.org/W2030324378","https://openalex.org/W2032846466","https://openalex.org/W2033473705","https://openalex.org/W2035053157","https://openalex.org/W2036163096","https://openalex.org/W2036187063","https://openalex.org/W2036507838","https://openalex.org/W2037296845","https://openalex.org/W2037636727","https://openalex.org/W2038089679","https://openalex.org/W2038599263","https://openalex.org/W2039073469","https://openalex.org/W2040236373","https://openalex.org/W2041731336","https://openalex.org/W2042114476","https://openalex.org/W2043029684","https://openalex.org/W2043173259","https://openalex.org/W2045104107","https://openalex.org/W2045618800","https://openalex.org/W2046186083","https://openalex.org/W2049082572","https://openalex.org/W2049088920","https://openalex.org/W2049692751","https://openalex.org/W2050003210","https://openalex.org/W2053667928","https://openalex.org/W2054088581","https://openalex.org/W2054110495","https://openalex.org/W2056787679","https://openalex.org/W2058910991","https://openalex.org/W2059725940","https://openalex.org/W2059824940","https://openalex.org/W2059854592","https://openalex.org/W2060254175","https://openalex.org/W2060762262","https://openalex.org/W2061077538","https://openalex.org/W2063210874","https://openalex.org/W2063603480","https://openalex.org/W2063635646","https://openalex.org/W2064988355","https://openalex.org/W2065607401","https://openalex.org/W2066338529","https://openalex.org/W2068249996","https://openalex.org/W2069665561","https://openalex.org/W2070139517","https://openalex.org/W2070356876","https://openalex.org/W2070438989","https://openalex.org/W2070803894","https://openalex.org/W2071762564","https://openalex.org/W2072154498","https://openalex.org/W2074082111","https://openalex.org/W2074520087","https://openalex.org/W2075891689","https://openalex.org/W2077425012","https://openalex.org/W2077895426","https://openalex.org/W2079077642","https://openalex.org/W2079437764","https://openalex.org/W2079731894","https://openalex.org/W2080441443","https://openalex.org/W2081578669","https://openalex.org/W2082263940","https://openalex.org/W2082921977","https://openalex.org/W2084597656","https://openalex.org/W2086367664","https://openalex.org/W2087819096","https://openalex.org/W2088814957","https://openalex.org/W2091126412","https://openalex.org/W2091446403","https://openalex.org/W2091474004","https://openalex.org/W2102884007","https://openalex.org/W2102957365","https://openalex.org/W2107196385","https://openalex.org/W2107201710","https://openalex.org/W2107370312","https://openalex.org/W2108573310","https://openalex.org/W2109053359","https://openalex.org/W2111723991","https://openalex.org/W2111908683","https://openalex.org/W2114324710","https://openalex.org/W2115194082","https://openalex.org/W2115399730","https://openalex.org/W2117213785","https://openalex.org/W2118921112","https://openalex.org/W2122493291","https://openalex.org/W2123119516","https://openalex.org/W2124281635","https://openalex.org/W2125145927","https://openalex.org/W2127858258","https://openalex.org/W2131515455","https://openalex.org/W2133014036","https://openalex.org/W2135735684","https://openalex.org/W2138688189","https://openalex.org/W2140332605","https://openalex.org/W2141139112","https://openalex.org/W2143505927","https://openalex.org/W2145543256","https://openalex.org/W2146798664","https://openalex.org/W2148638301","https://openalex.org/W2150132984","https://openalex.org/W2152211310","https://openalex.org/W2152504043","https://openalex.org/W2152786002","https://openalex.org/W2153038533","https://openalex.org/W2153085335","https://openalex.org/W2153586676","https://openalex.org/W2153614027","https://openalex.org/W2153671031","https://openalex.org/W2155118287","https://openalex.org/W2155843602","https://openalex.org/W2156899873","https://openalex.org/W2157277051","https://openalex.org/W2159953069","https://openalex.org/W2163075259","https://openalex.org/W2163094253","https://openalex.org/W2164293863","https://openalex.org/W2165090993","https://openalex.org/W2168923588","https://openalex.org/W2169378022","https://openalex.org/W2169512585","https://openalex.org/W2171223091","https://openalex.org/W2171457359","https://openalex.org/W2182566969","https://openalex.org/W2188653430","https://openalex.org/W2334875551","https://openalex.org/W2401964422","https://openalex.org/W2404994480","https://openalex.org/W2610697518","https://openalex.org/W4211199394","https://openalex.org/W4299579025","https://openalex.org/W6603669592"],"related_works":["https://openalex.org/W1966261578","https://openalex.org/W2012222816","https://openalex.org/W2141240449","https://openalex.org/W6982622529","https://openalex.org/W2036187063","https://openalex.org/W7135219264","https://openalex.org/W2165090993","https://openalex.org/W2593404140","https://openalex.org/W2003317794","https://openalex.org/W2066261526"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":15},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":13},{"year":2019,"cited_by_count":12},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":13},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":8}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
