{"id":"https://openalex.org/W2054778613","doi":"https://doi.org/10.1097/00019501-199209000-00011","title":"Human cadaveric coronary artery vasoreactivity is dependent on anatomic location and postmortem interval","display_name":"Human cadaveric coronary artery vasoreactivity is dependent on anatomic location and postmortem interval","publication_year":1992,"publication_date":"1992-09-01","ids":{"openalex":"https://openalex.org/W2054778613","doi":"https://doi.org/10.1097/00019501-199209000-00011","mag":"2054778613"},"language":"en","primary_location":{"id":"doi:10.1097/00019501-199209000-00011","doi":"https://doi.org/10.1097/00019501-199209000-00011","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00019501-199209000-00011","pdf_url":null,"source":{"id":"https://openalex.org/S31433238","display_name":"Coronary Artery Disease","issn_l":"0954-6928","issn":["0954-6928","1473-5830"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Coronary Artery Disease","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112222208","display_name":"Chris Suhr","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Chris Suhr","raw_affiliation_strings":["Surgery","Duke University Medical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Surgery","institution_ids":[]},{"raw_affiliation_string":"Duke University Medical Center","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027120100","display_name":"Mark G. Davies","orcid":"https://orcid.org/0000-0001-7789-512X","observed_orcids":["https://orcid.org/0000-0001-7789-512X"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mark G. Davies","raw_affiliation_strings":["Surgery","Duke University Medical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Surgery","institution_ids":[]},{"raw_affiliation_string":"Duke University Medical Center","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003810132","display_name":"Lewis B. Schwartz","orcid":"https://orcid.org/0000-0003-0079-9361","observed_orcids":["https://orcid.org/0000-0003-0079-9361"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Lewis B. Schwartz","raw_affiliation_strings":["Surgery","Duke University Medical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Surgery","institution_ids":[]},{"raw_affiliation_string":"Duke University Medical Center","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073805363","display_name":"Martin K. O\u02bcDonohoe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martin K. O\u02bcDonohoe","raw_affiliation_strings":["Duke University Medical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke University Medical Center","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049116995","display_name":"Eileen M. Mikat","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eileen M. Mikat","raw_affiliation_strings":["Pathology, and","Duke University Medical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pathology, and","institution_ids":[]},{"raw_affiliation_string":"Duke University Medical Center","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111573520","display_name":"Per\u2010Otto Hagen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Per-Otto Hagen","raw_affiliation_strings":["Surgery","Duke University Medical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Surgery","institution_ids":[]},{"raw_affiliation_string":"Duke University Medical Center","institution_ids":["https://openalex.org/I4210126298"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5003810132","https://openalex.org/A5027120100","https://openalex.org/A5111573520","https://openalex.org/A5112222208"],"corresponding_institution_ids":["https://openalex.org/I4210126298"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.18326744,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"3","issue":"9","first_page":"847","last_page":"852"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.6104000210762024,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.6104000210762024,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.10520000010728836,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.04989999905228615,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/right-coronary-artery","display_name":"right coronary artery","score":0.9760000109672546},{"id":"https://openalex.org/keywords/left-anterior-descending-artery","display_name":"left anterior descending artery","score":0.9919999837875366},{"id":"https://openalex.org/keywords/left-circumflex-artery","display_name":"left circumflex artery","score":0.9990000128746033},{"id":"https://openalex.org/keywords/anatomical-location","display_name":"anatomical location","score":0.7680000066757202},{"id":"https://openalex.org/keywords/postmortem-interval","display_name":"postmortem interval","score":0.9980000257492065},{"id":"https://openalex.org/keywords/norepinephrine","display_name":"norepinephrine","score":0.921999990940094},{"id":"https://openalex.org/keywords/acetylcholine","display_name":"acetylcholine","score":0.9150000214576721},{"id":"https://openalex.org/keywords/histamine","display_name":"histamine","score":0.9079999923706055},{"id":"https://openalex.org/keywords/serotonin","display_name":"serotonin","score":0.9950000047683716},{"id":"https://openalex.org/keywords/potassium-induced-contraction","display_name":"potassium-induced contraction","score":0.5440000295639038},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.7519999742507935}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9095754027366638},{"id":"https://openalex.org/C2776820930","wikidata":"https://www.wikidata.org/wiki/Q9655","display_name":"Artery","level":2,"score":0.6366441249847412},{"id":"https://openalex.org/C197321550","wikidata":"https://www.wikidata.org/wiki/Q11175","display_name":"Circumflex","level":3,"score":0.634534478187561},{"id":"https://openalex.org/C2776214587","wikidata":"https://www.wikidata.org/wiki/Q3430227","display_name":"Vasomotor","level":2,"score":0.5980588793754578},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.561223030090332},{"id":"https://openalex.org/C2778742706","wikidata":"https://www.wikidata.org/wiki/Q18361829","display_name":"Coronary arteries","level":3,"score":0.4628177881240845},{"id":"https://openalex.org/C2778088351","wikidata":"https://www.wikidata.org/wiki/Q429285","display_name":"Right coronary artery","level":4,"score":0.45544859766960144},{"id":"https://openalex.org/C175696284","wikidata":"https://www.wikidata.org/wiki/Q986524","display_name":"Cadaveric spasm","level":2,"score":0.437730073928833},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.43105950951576233},{"id":"https://openalex.org/C103486182","wikidata":"https://www.wikidata.org/wiki/Q1216236","display_name":"Isometric exercise","level":2,"score":0.4117445647716522},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.40950673818588257},{"id":"https://openalex.org/C3019004856","wikidata":"https://www.wikidata.org/wiki/Q42297149","display_name":"Coronary angiography","level":3,"score":0.14774155616760254},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1097/00019501-199209000-00011","doi":"https://doi.org/10.1097/00019501-199209000-00011","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00019501-199209000-00011","pdf_url":null,"source":{"id":"https://openalex.org/S31433238","display_name":"Coronary Artery Disease","issn_l":"0954-6928","issn":["0954-6928","1473-5830"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Coronary Artery Disease","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8048999905586243}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.4399999976158142}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2509052907","https://openalex.org/W7208101406","https://openalex.org/W2069559935","https://openalex.org/W2035848669","https://openalex.org/W2076085549","https://openalex.org/W2125041445","https://openalex.org/W2404176356","https://openalex.org/W2112590792","https://openalex.org/W190761668","https://openalex.org/W7099561849"],"abstract_inverted_index":{"Background":[0],"Clinical":[1],"observations":[2],"suggest":[3],"that":[4,106,181],"the":[5,17,24,113,134,139,155,179,182],"right":[6],"coronary":[7,35],"artery":[8,21,27],"(RCA)":[9],"has":[10,184],"a":[11,107,127,185],"different":[12,186],"vasoreactivity":[13],"when":[14],"compared":[15],"with":[16,72],"left":[18,25,135],"anterior":[19],"descending":[20],"(LAD)":[22],"and":[23,76,89,145,158,169],"circumflex":[26],"(LCx).":[28],"Methods":[29],"The":[30,104,124],"proximal":[31],"segment":[32],"of":[33,91,95,102,117,133,138],"31":[34,96],"vessels":[36,51,97,118],"(11":[37],"RCA,":[38,156],"11":[39,46],"LAD,":[40,157],"nine":[41],"LCx)":[42],"were":[43,52,70,160],"harvested":[44,119],"from":[45,49,154],"donors.":[47],"Rings":[48],"these":[50,79],"suspended":[53],"in":[54],"organ":[55],"baths":[56],"containing":[57],"physiologic":[58],"solution":[59],"at":[60],"37'C.":[61],"Isometric":[62],"tension":[63,130],"studies":[64,168],"using":[65],"cumulative":[66],"dose":[67,148],"response":[68,143],"curves":[69,144],"performed":[71],"norepinephrine,":[73],"serotonin,":[74],"histamine,":[75],"acetylcholine.":[77],"Following":[78],"studies,":[80],"each":[81,152],"ring":[82],"was":[83,163],"histologically":[84],"assessed":[85],"for":[86,151],"morphometric":[87,173],"changes":[88],"signs":[90],"atherosclerosis.":[92],"Results":[93],"Eleven":[94],"reacted":[98],"to":[99],"60":[100],"mmol/L":[101],"KCI.":[103],"probability":[105],"vessel":[108],"would":[109],"respond":[110],"depended":[111],"on":[112],"postmortem":[114,140],"interval;":[115],"88%":[116],"within":[120],"4":[121],"hours":[122],"reacted.":[123],"RCA":[125,183],"generated":[126],"greater":[128],"maximum":[129],"than":[131,189],"either":[132,170],"coronaries,":[136],"irrespective":[137],"interval.":[141],"Dose":[142],"median":[146],"effective":[147],"(ED50)":[149],"values":[150],"agonist":[153],"LCx":[159],"similar.":[161],"There":[162],"no":[164],"correlation":[165],"between":[166],"functional":[167],"morphology":[171],"or":[172],"measures.":[174],"Conclusions":[175],"This":[176],"study":[177],"supports":[178],"view":[180],"vasomotor":[187],"profile":[188],"its":[190],"left-sided":[191],"counterparts.":[192]},"counts_by_year":[],"updated_date":"2026-07-30T17:31:21.811387","created_date":"2016-06-24T00:00:00"}