{"id":"https://openalex.org/W2054564157","doi":"https://doi.org/10.1111/j.1574-695x.2006.00151.x","title":"Potential prophylactic value of bovine colostrum in necrotizing enterocolitis in neonates: anin vitrostudy on bacterial attachment, antibody levels and cytokine production","display_name":"Potential prophylactic value of bovine colostrum in necrotizing enterocolitis in neonates: anin vitrostudy on bacterial attachment, antibody levels and cytokine production","publication_year":2006,"publication_date":"2006-09-21","ids":{"openalex":"https://openalex.org/W2054564157","doi":"https://doi.org/10.1111/j.1574-695x.2006.00151.x","mag":"2054564157","pmid":"https://pubmed.ncbi.nlm.nih.gov/16995878"},"language":"en","primary_location":{"id":"doi:10.1111/j.1574-695x.2006.00151.x","doi":"https://doi.org/10.1111/j.1574-695x.2006.00151.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1574-695x.2006.00151.x","pdf_url":"https://academic.oup.com/femspd/article-pdf/48/3/347/19169478/48-3-347.pdf","source":{"id":"https://openalex.org/S136462399","display_name":"FEMS Immunology & Medical Microbiology","issn_l":"0928-8244","issn":["0928-8244","1574-695X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS Immunology &amp; Medical Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/femspd/article-pdf/48/3/347/19169478/48-3-347.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111565372","display_name":"Heather J. L. Brooks","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":true,"raw_author_name":"Heather J.L. Brooks","raw_affiliation_strings":["Department of Microbiology and Immunology, Otago School of Medical Sciences, New Zealand. heather.brooks@stonebow.otago.ac.nz","Department of Microbiology & Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Otago School of Medical Sciences, New Zealand. heather.brooks@stonebow.otago.ac.nz","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"Department of Microbiology & Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand","institution_ids":["https://openalex.org/I80281795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029576282","display_name":"Michelle A. McConnell","orcid":"https://orcid.org/0000-0002-2598-534X","observed_orcids":["https://orcid.org/0000-0002-2598-534X"]},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Michelle A. McConnell","raw_affiliation_strings":["Department of Microbiology and Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand","Department of Microbiology & Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"Department of Microbiology & Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand","institution_ids":["https://openalex.org/I80281795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012050253","display_name":"Janet Corbett","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Janet Corbett","raw_affiliation_strings":["Department of Microbiology and Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand","Department of Microbiology & Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"Department of Microbiology & Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand","institution_ids":["https://openalex.org/I80281795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108490235","display_name":"Glen S. Buchan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Glenn S. Buchan","raw_affiliation_strings":["Department of Microbiology and Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand","Department of Microbiology & Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"Department of Microbiology & Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand","institution_ids":["https://openalex.org/I80281795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063078313","display_name":"Clare Fitzpatrick","orcid":"https://orcid.org/0000-0001-9946-9252","observed_orcids":["https://orcid.org/0000-0001-9946-9252"]},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Clare E. Fitzpatrick","raw_affiliation_strings":["Department of Microbiology and Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand","Department of Microbiology & Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"Department of Microbiology & Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand","institution_ids":["https://openalex.org/I80281795"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082818462","display_name":"Roland S. Broadbent","orcid":"https://orcid.org/0000-0002-4628-7276","observed_orcids":["https://orcid.org/0000-0002-4628-7276"]},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Roland S. Broadbent","raw_affiliation_strings":["Department of Paediatrics and Child Health, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatrics and Child Health, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand","institution_ids":["https://openalex.org/I80281795"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5111565372"],"corresponding_institution_ids":["https://openalex.org/I80281795"],"apc_list":null,"apc_paid":null,"fwci":1.0531,"has_fulltext":true,"cited_by_count":32,"citation_normalized_percentile":{"value":0.76152519,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"48","issue":"3","first_page":"347","last_page":"354"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11294","display_name":"Infant Nutrition and Health","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11294","display_name":"Infant Nutrition and Health","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11961","display_name":"Neonatal and Maternal Infections","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12322","display_name":"Animal health and immunology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/necrotizing-enterocolitis","display_name":"necrotizing enterocolitis","score":0.9929999709129333},{"id":"https://openalex.org/keywords/bovine-colostrum","display_name":"bovine colostrum","score":0.9959999918937683},{"id":"https://openalex.org/keywords/prophylaxis","display_name":"prophylaxis","score":0.699999988079071},{"id":"https://openalex.org/keywords/low-birth-weight-infants","display_name":"low birth weight infants","score":0.8389999866485596},{"id":"https://openalex.org/keywords/bacterial-adhesion","display_name":"bacterial adhesion","score":0.7210000157356262},{"id":"https://openalex.org/keywords/enterobacteriaceae","display_name":"Enterobacteriaceae","score":0.8790000081062317},{"id":"https://openalex.org/keywords/iga-antibodies","display_name":"IgA antibodies","score":0.6639999747276306},{"id":"https://openalex.org/keywords/igg1-antibodies","display_name":"IgG1 antibodies","score":0.8579999804496765},{"id":"https://openalex.org/keywords/cytokine-production","display_name":"cytokine production","score":0.9279999732971191},{"id":"https://openalex.org/keywords/interleukin-8","display_name":"interleukin-8","score":0.9129999876022339},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.8849999904632568},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":1.0},{"id":"https://openalex.org/keywords/intestinal-mucosa","display_name":"intestinal mucosa","score":0.5040000081062317},{"id":"https://openalex.org/keywords/ht-29-cells","display_name":"HT-29 cells","score":0.7829999923706055},{"id":"https://openalex.org/keywords/thp-1-cells","display_name":"THP-1 cells","score":0.8939999938011169}],"concepts":[{"id":"https://openalex.org/C2779073587","wikidata":"https://www.wikidata.org/wiki/Q192746","display_name":"Colostrum","level":3,"score":0.8890885710716248},{"id":"https://openalex.org/C2779303187","wikidata":"https://www.wikidata.org/wiki/Q10859678","display_name":"Necrotizing enterocolitis","level":2,"score":0.7988713979721069},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.7482725381851196},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6882683038711548},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5745607614517212},{"id":"https://openalex.org/C2778910516","wikidata":"https://www.wikidata.org/wiki/Q380136","display_name":"Enterobacteriaceae","level":4,"score":0.5114573240280151},{"id":"https://openalex.org/C2777058267","wikidata":"https://www.wikidata.org/wiki/Q132592","display_name":"Klebsiella pneumoniae","level":4,"score":0.49968481063842773},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.4174809157848358},{"id":"https://openalex.org/C2776258884","wikidata":"https://www.wikidata.org/wiki/Q3055368","display_name":"Enterocolitis","level":2,"score":0.4173869788646698},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.4087989330291748},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4035790264606476},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.18376463651657104},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1516256034374237},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.06232857704162598},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001422","descriptor_name":"Bacterial Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003126","descriptor_name":"Colostrum","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D003126","descriptor_name":"Colostrum","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D004755","descriptor_name":"Enterobacteriaceae","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D004755","descriptor_name":"Enterobacteriaceae","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D004756","descriptor_name":"Enterobacteriaceae Infections","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D005243","descriptor_name":"Feces","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007070","descriptor_name":"Immunoglobulin A","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007070","descriptor_name":"Immunoglobulin A","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D007230","descriptor_name":"Infant, Low Birth Weight","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020345","descriptor_name":"Enterocolitis, Necrotizing","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D047928","descriptor_name":"Premature Birth","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1574-695x.2006.00151.x","doi":"https://doi.org/10.1111/j.1574-695x.2006.00151.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1574-695x.2006.00151.x","pdf_url":"https://academic.oup.com/femspd/article-pdf/48/3/347/19169478/48-3-347.pdf","source":{"id":"https://openalex.org/S136462399","display_name":"FEMS Immunology & Medical Microbiology","issn_l":"0928-8244","issn":["0928-8244","1574-695X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS Immunology &amp; Medical Microbiology","raw_type":"journal-article"},{"id":"pmid:16995878","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16995878","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS immunology and medical microbiology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1111/j.1574-695x.2006.00151.x","doi":"https://doi.org/10.1111/j.1574-695x.2006.00151.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1574-695x.2006.00151.x","pdf_url":"https://academic.oup.com/femspd/article-pdf/48/3/347/19169478/48-3-347.pdf","source":{"id":"https://openalex.org/S136462399","display_name":"FEMS Immunology & Medical Microbiology","issn_l":"0928-8244","issn":["0928-8244","1574-695X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEMS Immunology &amp; Medical Microbiology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729},{"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger","score":0.40450000762939453}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320310371","display_name":"University of Otago","ror":"https://ror.org/01jmxt844"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2054564157.pdf","grobid_xml":"https://content.openalex.org/works/W2054564157.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W75904336","https://openalex.org/W154138159","https://openalex.org/W1719598368","https://openalex.org/W1908128843","https://openalex.org/W1964351185","https://openalex.org/W1964377839","https://openalex.org/W1966509997","https://openalex.org/W1983606011","https://openalex.org/W1986936861","https://openalex.org/W1989825777","https://openalex.org/W1990612047","https://openalex.org/W1990981444","https://openalex.org/W1992597684","https://openalex.org/W1994340698","https://openalex.org/W2006858495","https://openalex.org/W2015250987","https://openalex.org/W2019284637","https://openalex.org/W2019549525","https://openalex.org/W2040543150","https://openalex.org/W2046875107","https://openalex.org/W2049645500","https://openalex.org/W2085319013","https://openalex.org/W2086361511","https://openalex.org/W2097900300","https://openalex.org/W2108581239","https://openalex.org/W2110706037","https://openalex.org/W2125200552","https://openalex.org/W2131006155","https://openalex.org/W2134206097","https://openalex.org/W2138017269","https://openalex.org/W2141953075","https://openalex.org/W2154395248","https://openalex.org/W2342029315","https://openalex.org/W2399964977","https://openalex.org/W2417448412"],"related_works":["https://openalex.org/W4414028210","https://openalex.org/W2417237734","https://openalex.org/W2011137612","https://openalex.org/W44941819","https://openalex.org/W2862773758","https://openalex.org/W2133213835","https://openalex.org/W2596445434","https://openalex.org/W2167546904","https://openalex.org/W2773711867","https://openalex.org/W4210486763"],"abstract_inverted_index":{"Necrotizing":[0],"enterocolitis":[1],"(NEC)":[2],"is":[3,48],"an":[4],"important":[5],"disease":[6],"of":[7,13,37,55,93,99,159,170,186,193],"low":[8],"birth-weight":[9],"neonates.":[10],"The":[11,53,91,184],"immaturity":[12],"the":[14,23,33,38,97,145,168,191],"gut":[15,34],"mucosa":[16,39],"may":[17],"result":[18],"in":[19,67,102,126,144,157,172,180],"close":[20],"contact":[21],"between":[22],"host":[24],"epithelium":[25],"and":[26,82,119,130,134,136,175,178],"microorganisms":[27],"which":[28],"are":[29],"normally":[30],"confined":[31],"to":[32,41,50,59,139,161,189],"lumen.":[35],"Damage":[36],"due":[40],"endotoxin,":[42],"cytokine":[43],"production":[44,98,169,192],"or":[45],"other":[46],"factors":[47],"believed":[49],"then":[51],"occur.":[52],"aim":[54],"this":[56],"study":[57],"was":[58,75,104],"determine":[60],"whether":[61],"spray-dried":[62],"bovine":[63,94,146,150,187],"colostrum":[64,95,151,165,188],"demonstrated":[65],"potential":[66,185],"vitro":[68],"as":[69],"a":[70,78,107,153],"prophylactic":[71],"for":[72],"NEC.":[73],"Antiadherence":[74],"measured":[76],"using":[77],"tissue":[79],"culture":[80],"assay":[81],"antibody":[83],"levels":[84],"against":[85],"Enterobacteriaceae":[86],"were":[87,124,142],"determined":[88,105],"by":[89,106],"ELISA.":[90],"effect":[92],"on":[96],"cytokines":[100],"implicated":[101],"NEC":[103,128,131],"multiplex":[108],"bead":[109],"assay.":[110],"Enterobacter":[111],"cloacae,":[112],"Klebsiella":[113,120],"oxytoca,":[114],"Escherichia":[115],"coli,":[116],"Serratia":[117],"marcescens":[118],"pneumoniae":[121,123],"ssp.":[122],"common":[125],"both":[127],"positive":[129],"negative":[132],"infants":[133],"IgA":[135],"IgG1":[137],"antibodies":[138],"these":[140],"species":[141],"present":[143],"colostrum.":[147],"Pretreatment":[148],"with":[149],"produced":[152],"significant":[154],"decrease":[155],"(P<0.001)":[156],"attachment":[158],"bacteria":[160],"HT-29":[162,173],"cells.":[163],"Bovine":[164],"significantly":[166],"increased":[167],"IL-8":[171],"cells":[174,182],"IL-8,":[176],"IL-6":[177],"TNF-alpha":[179],"THP-1":[181],"(P<0.001).":[183],"increase":[190],"inflammatory":[194],"mediators":[195],"could":[196],"limit":[197],"its":[198],"usefulness.":[199]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}