{"id":"https://openalex.org/W2054536767","doi":"https://doi.org/10.1016/j.clineuro.2013.08.018","title":"Increased ventriculostomy infection rate with use of intraventricular tissue plasminogen activator: A single-center observation","display_name":"Increased ventriculostomy infection rate with use of intraventricular tissue plasminogen activator: A single-center observation","publication_year":2013,"publication_date":"2013-08-27","ids":{"openalex":"https://openalex.org/W2054536767","doi":"https://doi.org/10.1016/j.clineuro.2013.08.018","mag":"2054536767","pmid":"https://pubmed.ncbi.nlm.nih.gov/24034819"},"language":"en","primary_location":{"id":"doi:10.1016/j.clineuro.2013.08.018","doi":"https://doi.org/10.1016/j.clineuro.2013.08.018","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.clineuro.2013.08.018","pdf_url":null,"source":{"id":"https://openalex.org/S165396890","display_name":"Clinical Neurology and Neurosurgery","issn_l":"0303-8467","issn":["0303-8467","1872-6968"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Neurology and Neurosurgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082103572","display_name":"Andrew J. Fabiano","orcid":"https://orcid.org/0000-0001-9991-6171","observed_orcids":["https://orcid.org/0000-0001-9991-6171"]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]},{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Andrew J. Fabiano","raw_affiliation_strings":["Department of Neurosurgery, School of Medicine and Biomedical Sciences, Buffalo, USA; Department of Neurosurgery, Roswell Park Cancer Institute, Buffalo, USA. Electronic address: Andrew.Fabiano@RoswellPark.org","Department of Neurosurgery, Roswell Park Cancer Institute, Buffalo, USA","Department of Neurosurgery, School of Medicine and Biomedical Sciences, Buffalo, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, School of Medicine and Biomedical Sciences, Buffalo, USA; Department of Neurosurgery, Roswell Park Cancer Institute, Buffalo, USA. Electronic address: Andrew.Fabiano@RoswellPark.org","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"Department of Neurosurgery, Roswell Park Cancer Institute, Buffalo, USA","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"Department of Neurosurgery, School of Medicine and Biomedical Sciences, Buffalo, USA","institution_ids":["https://openalex.org/I63190737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070961411","display_name":"Thomas Gruber","orcid":"https://orcid.org/0000-0001-5210-1995","observed_orcids":["https://orcid.org/0000-0001-5210-1995"]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]},{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas J. Gruber","raw_affiliation_strings":["Department of Neurosurgery, Roswell Park Cancer Institute, Buffalo, USA","Department of Neurosurgery, School of Medicine and Biomedical Sciences, Buffalo, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Roswell Park Cancer Institute, Buffalo, USA","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"Department of Neurosurgery, School of Medicine and Biomedical Sciences, Buffalo, USA","institution_ids":["https://openalex.org/I63190737"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043871594","display_name":"Melissa S. Baxter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1325611130","display_name":"Kaleida Health","ror":"https://ror.org/02sb3pg33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1325611130"]},{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Melissa S. Baxter","raw_affiliation_strings":["Department of Neurology/Critical Care, Kaleida Health, Buffalo, USA","School of Pharmacy, University at Buffalo, State University of New York, Buffalo, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology/Critical Care, Kaleida Health, Buffalo, USA","institution_ids":["https://openalex.org/I1325611130"]},{"raw_affiliation_string":"School of Pharmacy, University at Buffalo, State University of New York, Buffalo, USA","institution_ids":["https://openalex.org/I63190737"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5082103572"],"corresponding_institution_ids":["https://openalex.org/I1292894508","https://openalex.org/I63190737"],"apc_list":{"value":3740,"currency":"USD","value_usd":3740},"apc_paid":null,"fwci":0.77,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.70582006,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"115","issue":"11","first_page":"2362","last_page":"2364"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11406","display_name":"Cerebrospinal fluid and hydrocephalus","score":0.14139999449253082,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11406","display_name":"Cerebrospinal fluid and hydrocephalus","score":0.14139999449253082,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11763","display_name":"Intracerebral and Subarachnoid Hemorrhage Research","score":0.13130000233650208,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10641","display_name":"Central Venous Catheters and Hemodialysis","score":0.08919999748468399,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tissue-plasminogen-activator","display_name":"tissue plasminogen activator","score":0.9779999852180481},{"id":"https://openalex.org/keywords/external-ventricular-drainage","display_name":"external ventricular drainage","score":0.8500000238418579},{"id":"https://openalex.org/keywords/ventriculitis","display_name":"ventriculitis","score":0.9860000014305115},{"id":"https://openalex.org/keywords/infection-rate","display_name":"infection rate","score":0.5709999799728394},{"id":"https://openalex.org/keywords/aneurysmal-subarachnoid-hemorrhage","display_name":"aneurysmal subarachnoid hemorrhage","score":0.9150000214576721},{"id":"https://openalex.org/keywords/intraventricular-hemorrhage","display_name":"intraventricular hemorrhage","score":0.8679999709129333},{"id":"https://openalex.org/keywords/vasospasm","display_name":"vasospasm","score":0.7310000061988831},{"id":"https://openalex.org/keywords/intracranial-pressure","display_name":"intracranial pressure","score":0.6549999713897705},{"id":"https://openalex.org/keywords/hydrocephalus","display_name":"hydrocephalus","score":0.7639999985694885}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9559177160263062},{"id":"https://openalex.org/C2779862588","wikidata":"https://www.wikidata.org/wiki/Q7920329","display_name":"Ventriculitis","level":3,"score":0.948287844657898},{"id":"https://openalex.org/C2779252433","wikidata":"https://www.wikidata.org/wiki/Q6058597","display_name":"Intraventricular hemorrhage","level":4,"score":0.9150519371032715},{"id":"https://openalex.org/C2778604727","wikidata":"https://www.wikidata.org/wiki/Q7920328","display_name":"Ventriculostomy","level":3,"score":0.8753116130828857},{"id":"https://openalex.org/C2778863898","wikidata":"https://www.wikidata.org/wiki/Q5422058","display_name":"External ventricular drain","level":3,"score":0.6421738862991333},{"id":"https://openalex.org/C2777736543","wikidata":"https://www.wikidata.org/wiki/Q693442","display_name":"Subarachnoid hemorrhage","level":2,"score":0.5912981033325195},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5868024230003357},{"id":"https://openalex.org/C2778134817","wikidata":"https://www.wikidata.org/wiki/Q193003","display_name":"Hydrocephalus","level":2,"score":0.536423921585083},{"id":"https://openalex.org/C2780954326","wikidata":"https://www.wikidata.org/wiki/Q1416096","display_name":"Intracranial pressure","level":2,"score":0.5290343165397644},{"id":"https://openalex.org/C2776572282","wikidata":"https://www.wikidata.org/wiki/Q416351","display_name":"Tissue plasminogen activator","level":2,"score":0.5035211443901062},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.40960636734962463},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17609775066375732},{"id":"https://openalex.org/C2778376644","wikidata":"https://www.wikidata.org/wiki/Q2253111","display_name":"Gestational age","level":3,"score":0.07664012908935547},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D002543","descriptor_name":"Cerebral Hemorrhage","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D002543","descriptor_name":"Cerebral Hemorrhage","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006849","descriptor_name":"Hydrocephalus","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006849","descriptor_name":"Hydrocephalus","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010959","descriptor_name":"Tissue Plasminogen Activator","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D013530","descriptor_name":"Surgical Wound Infection","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D014696","descriptor_name":"Ventriculostomy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D014696","descriptor_name":"Ventriculostomy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D015912","descriptor_name":"Thrombolytic Therapy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D015912","descriptor_name":"Thrombolytic Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.clineuro.2013.08.018","doi":"https://doi.org/10.1016/j.clineuro.2013.08.018","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.clineuro.2013.08.018","pdf_url":null,"source":{"id":"https://openalex.org/S165396890","display_name":"Clinical Neurology and Neurosurgery","issn_l":"0303-8467","issn":["0303-8467","1872-6968"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Neurology and Neurosurgery","raw_type":"journal-article"},{"id":"pmid:24034819","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24034819","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical neurology and neurosurgery","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W207375174","https://openalex.org/W1482839755","https://openalex.org/W1972824726","https://openalex.org/W2003813570","https://openalex.org/W2022503775","https://openalex.org/W2038492843","https://openalex.org/W2043525312","https://openalex.org/W2059133966","https://openalex.org/W2062401917","https://openalex.org/W2099766722","https://openalex.org/W2123151566","https://openalex.org/W2125301498","https://openalex.org/W2137356596","https://openalex.org/W2162751809","https://openalex.org/W2163411946","https://openalex.org/W2172067976"],"related_works":["https://openalex.org/W6890006079","https://openalex.org/W2895913334","https://openalex.org/W7140237365","https://openalex.org/W2920343243","https://openalex.org/W2313827727","https://openalex.org/W4413973324","https://openalex.org/W185205356","https://openalex.org/W2011423284","https://openalex.org/W2910939241","https://openalex.org/W2778343396"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}