{"id":"https://openalex.org/W205415841","doi":null,"title":"The Impact of Antiretroviral Therapy on the HIV Epidemic in South Africa","display_name":"The Impact of Antiretroviral Therapy on the HIV Epidemic in South Africa","publication_year":2013,"publication_date":"2013-02-12","ids":{"openalex":"https://openalex.org/W205415841","mag":"205415841"},"language":"en","primary_location":{"id":"pmh:eur:oai:pure.eur.nl:publications/d4ce727d-ec6d-49e1-bfe8-3412726f3b31","doi":null,"is_oa":true,"landing_page_url":"https://pure.eur.nl/en/publications/d4ce727d-ec6d-49e1-bfe8-3412726f3b31","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pure.eur.nl/en/publications/d4ce727d-ec6d-49e1-bfe8-3412726f3b31","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081387966","display_name":"Jan A. C. Hontelez","orcid":"https://orcid.org/0000-0002-9323-7861","observed_orcids":["https://orcid.org/0000-0002-9323-7861"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jan A. C. Hontelez","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9323-7861","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5081387966"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.7939000129699707,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.7939000129699707,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14334","display_name":"HIV/AIDS Impact and Responses","score":0.20309999585151672,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antiretroviral-therapy","display_name":"antiretroviral therapy","score":0.9750000238418579},{"id":"https://openalex.org/keywords/hiv-aids-epidemic","display_name":"HIV/AIDS epidemic","score":0.9570000171661377},{"id":"https://openalex.org/keywords/hiv-aids","display_name":"HIV/AIDS","score":0.7379999756813049},{"id":"https://openalex.org/keywords/south-africa","display_name":"South Africa","score":0.9070000052452087},{"id":"https://openalex.org/keywords/hiv-prevalence","display_name":"HIV prevalence","score":0.890999972820282},{"id":"https://openalex.org/keywords/hiv-incidence","display_name":"HIV incidence","score":0.9539999961853027},{"id":"https://openalex.org/keywords/treatment-access","display_name":"treatment access","score":0.656000018119812},{"id":"https://openalex.org/keywords/sub-saharan-africa","display_name":"sub-Saharan Africa","score":0.6869999766349792}],"concepts":[{"id":"https://openalex.org/C89623803","wikidata":"https://www.wikidata.org/wiki/Q12184","display_name":"Pandemic","level":5,"score":0.7333837747573853},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.6023062467575073},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5545861124992371},{"id":"https://openalex.org/C2993143319","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral therapy","level":4,"score":0.5173144340515137},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.47748634219169617},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.41844531893730164},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.3861110806465149},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.361737459897995},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.35432225465774536},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3400953412055969},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.2629634439945221},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.220744788646698},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.19766291975975037},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.16750425100326538},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"pmh:eur:oai:pure.eur.nl:publications/d4ce727d-ec6d-49e1-bfe8-3412726f3b31","doi":null,"is_oa":true,"landing_page_url":"https://pure.eur.nl/en/publications/d4ce727d-ec6d-49e1-bfe8-3412726f3b31","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},{"id":"pmh:eur:oai:repub.eur.nl:38922","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1765/38922","pdf_url":null,"source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},{"id":"pmh:oai:pure.eur.nl:openaire/d4ce727d-ec6d-49e1-bfe8-3412726f3b31","doi":null,"is_oa":true,"landing_page_url":"https://pure.eur.nl/en/publications/d4ce727d-ec6d-49e1-bfe8-3412726f3b31","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Hontelez, J 2013, 'The impact of antiretroviral therapy on the HIV epidemic in South Africa', Erasmus University Rotterdam. < http://hdl.handle.net/1765/38922 >","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"pmh:oai:repub.eur.nl:38922","doi":null,"is_oa":true,"landing_page_url":"http://repub.eur.nl/pub/38922","pdf_url":null,"source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:205415841","doi":null,"is_oa":false,"landing_page_url":"https://repub.eur.nl/pub/38922/130212_Hontelez,%20Jan%20Anton%20Charles.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:eur:oai:pure.eur.nl:publications/d4ce727d-ec6d-49e1-bfe8-3412726f3b31","doi":null,"is_oa":true,"landing_page_url":"https://pure.eur.nl/en/publications/d4ce727d-ec6d-49e1-bfe8-3412726f3b31","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":207,"referenced_works":["https://openalex.org/W319750121","https://openalex.org/W572708559","https://openalex.org/W1488109698","https://openalex.org/W1509099686","https://openalex.org/W1513979142","https://openalex.org/W1518709149","https://openalex.org/W1519721807","https://openalex.org/W1523296834","https://openalex.org/W1531381717","https://openalex.org/W1586408319","https://openalex.org/W1709113060","https://openalex.org/W1715086900","https://openalex.org/W1725500992","https://openalex.org/W1726363159","https://openalex.org/W1759385644","https://openalex.org/W1767940945","https://openalex.org/W1775651592","https://openalex.org/W1810964460","https://openalex.org/W1821150154","https://openalex.org/W1951551934","https://openalex.org/W1967855332","https://openalex.org/W1969398640","https://openalex.org/W1969773628","https://openalex.org/W1970023565","https://openalex.org/W1972596894","https://openalex.org/W1973112287","https://openalex.org/W1973502739","https://openalex.org/W1973540642","https://openalex.org/W1973574325","https://openalex.org/W1975596284","https://openalex.org/W1977510678","https://openalex.org/W1979479035","https://openalex.org/W1983867919","https://openalex.org/W1985718812","https://openalex.org/W1985999222","https://openalex.org/W1986413749","https://openalex.org/W1987677291","https://openalex.org/W1989840814","https://openalex.org/W1993459224","https://openalex.org/W1993586071","https://openalex.org/W1995734712","https://openalex.org/W1996682693","https://openalex.org/W1998959858","https://openalex.org/W2000389746","https://openalex.org/W2001602693","https://openalex.org/W2002395312","https://openalex.org/W2003737019","https://openalex.org/W2004796450","https://openalex.org/W2005025881","https://openalex.org/W2005065888","https://openalex.org/W2005240331","https://openalex.org/W2007856240","https://openalex.org/W2009747248","https://openalex.org/W2011124099","https://openalex.org/W2011352194","https://openalex.org/W2013194745","https://openalex.org/W2013553475","https://openalex.org/W2015921173","https://openalex.org/W2016503102","https://openalex.org/W2017391004","https://openalex.org/W2017588974","https://openalex.org/W2017665958","https://openalex.org/W2017741980","https://openalex.org/W2019941399","https://openalex.org/W2022204136","https://openalex.org/W2023155600","https://openalex.org/W2025310685","https://openalex.org/W2026315728","https://openalex.org/W2027032510","https://openalex.org/W2027138223","https://openalex.org/W2029077795","https://openalex.org/W2031011247","https://openalex.org/W2032003852","https://openalex.org/W2034414496","https://openalex.org/W2035384552","https://openalex.org/W2035967521","https://openalex.org/W2037789241","https://openalex.org/W2041843949","https://openalex.org/W2042030257","https://openalex.org/W2043610326","https://openalex.org/W2043773111","https://openalex.org/W2045918174","https://openalex.org/W2052191760","https://openalex.org/W2052343492","https://openalex.org/W2055164441","https://openalex.org/W2056539403","https://openalex.org/W2057912078","https://openalex.org/W2058716636","https://openalex.org/W2059016715","https://openalex.org/W2059094993","https://openalex.org/W2064189789","https://openalex.org/W2067620037","https://openalex.org/W2067997434","https://openalex.org/W2070463461","https://openalex.org/W2070838708","https://openalex.org/W2072778571","https://openalex.org/W2074548537","https://openalex.org/W2074918485","https://openalex.org/W2077748901","https://openalex.org/W2078212821","https://openalex.org/W2081513488","https://openalex.org/W2085314223","https://openalex.org/W2087883639","https://openalex.org/W2089695096","https://openalex.org/W2090189762","https://openalex.org/W2091174536","https://openalex.org/W2092473121","https://openalex.org/W2095718569","https://openalex.org/W2095748010","https://openalex.org/W2096563607","https://openalex.org/W2097264928","https://openalex.org/W2098729341","https://openalex.org/W2098774775","https://openalex.org/W2098985784","https://openalex.org/W2099125001","https://openalex.org/W2099946852","https://openalex.org/W2100430786","https://openalex.org/W2105517048","https://openalex.org/W2105897353","https://openalex.org/W2108987180","https://openalex.org/W2109992855","https://openalex.org/W2111596760","https://openalex.org/W2112509042","https://openalex.org/W2112791146","https://openalex.org/W2113071805","https://openalex.org/W2115373328","https://openalex.org/W2117605859","https://openalex.org/W2118161701","https://openalex.org/W2118399528","https://openalex.org/W2119070248","https://openalex.org/W2119835296","https://openalex.org/W2120944044","https://openalex.org/W2120953033","https://openalex.org/W2120986885","https://openalex.org/W2122050550","https://openalex.org/W2123369272","https://openalex.org/W2124995497","https://openalex.org/W2126051734","https://openalex.org/W2127832030","https://openalex.org/W2128871732","https://openalex.org/W2129442477","https://openalex.org/W2131295062","https://openalex.org/W2131895686","https://openalex.org/W2131976757","https://openalex.org/W2133151084","https://openalex.org/W2133773667","https://openalex.org/W2134536627","https://openalex.org/W2134646440","https://openalex.org/W2134911122","https://openalex.org/W2135552714","https://openalex.org/W2137128893","https://openalex.org/W2137160100","https://openalex.org/W2138893160","https://openalex.org/W2139894829","https://openalex.org/W2140083708","https://openalex.org/W2141332234","https://openalex.org/W2142560219","https://openalex.org/W2143071104","https://openalex.org/W2143079142","https://openalex.org/W2143265231","https://openalex.org/W2146428988","https://openalex.org/W2147600982","https://openalex.org/W2148207513","https://openalex.org/W2148970839","https://openalex.org/W2149137131","https://openalex.org/W2150576050","https://openalex.org/W2151573279","https://openalex.org/W2151768324","https://openalex.org/W2152048324","https://openalex.org/W2152322381","https://openalex.org/W2152505869","https://openalex.org/W2152873893","https://openalex.org/W2152896082","https://openalex.org/W2153244256","https://openalex.org/W2153777745","https://openalex.org/W2153856825","https://openalex.org/W2154243411","https://openalex.org/W2156504984","https://openalex.org/W2157890309","https://openalex.org/W2158326431","https://openalex.org/W2158666805","https://openalex.org/W2160384033","https://openalex.org/W2161725179","https://openalex.org/W2162189997","https://openalex.org/W2162453648","https://openalex.org/W2163036286","https://openalex.org/W2163124589","https://openalex.org/W2165032352","https://openalex.org/W2165184562","https://openalex.org/W2165681167","https://openalex.org/W2165974914","https://openalex.org/W2166942539","https://openalex.org/W2168300755","https://openalex.org/W2168445160","https://openalex.org/W2169164586","https://openalex.org/W2169249122","https://openalex.org/W2169366011","https://openalex.org/W2169980588","https://openalex.org/W2313070808","https://openalex.org/W2314461521","https://openalex.org/W2316610266","https://openalex.org/W2318289184","https://openalex.org/W2330254694","https://openalex.org/W2341804666","https://openalex.org/W2409146529","https://openalex.org/W2613400565","https://openalex.org/W3144185567"],"related_works":["https://openalex.org/W7096668307","https://openalex.org/W2257454627","https://openalex.org/W2043382431","https://openalex.org/W2182674489","https://openalex.org/W2014114500","https://openalex.org/W2614551591","https://openalex.org/W7209308936","https://openalex.org/W2257462418","https://openalex.org/W2034370616","https://openalex.org/W1526136348"],"abstract_inverted_index":{"The":[0],"Human":[1],"Immunodeficiency":[2],"Virus":[3],"(HIV)":[4],"is":[5,121],"the":[6,18,21,25,41,65,75,84,99,122,125,136,141,152,161],"cause":[7],"of":[8,20,27,40,53,57,69,132,157],"Acquired":[9],"Immune":[10],"Deficiency\\nSyndrome":[11],"(AIDS),":[12],"a":[13,182],"lethal":[14],"disease":[15],"characterized":[16],"by":[17,98],"destruction":[19],"immune":[22],"system.":[23],"At":[24],"end":[26],"2010,":[28],"there":[29,78],"were":[30,79,177],"about":[31,133,144,170],"34":[32],"million":[33,146,172,185],"people":[34,59,147,173],"infected":[35,174],"with":[36,50,61,124,149,175],"HIV":[37,42,62,176],"worldwide.\\nThe":[38],"epicenter":[39],"pandemic":[43],"lies":[44],"in":[45,64,86,91,135,160],"sub-Saharan":[46],"Africa":[47,120],"(figure":[48],"1.1):":[49],"only":[51],"12%":[52],"the\\nworld\u2019s":[54],"population,":[55],"68%":[56],"all":[58],"living":[60,148],"live":[63],"subcontinent.":[66],"Although":[67],"the\\nnumber":[68,156],"new":[70,158],"infections":[71,159],"worldwide":[72],"declined":[73],"over":[74],"past":[76,153],"decades,":[77],"an":[80],"estimated":[81,187],"2.7\\nmillion":[82],"acquired":[83],"infection":[85],"2010":[87],"[3].":[88],"Especially":[89],"countries":[90,102],"Eastern":[92],"and":[93],"Southern":[94],"Africa\\nare":[95],"heavily":[96],"affected":[97],"pandemic.":[100],"In":[101],"like":[103],"Botswana":[104],"or":[105],"Swaziland":[106],"prevalence":[107,130],"levels":[108,131,166],"in\\nthe":[109],"adult":[110],"population":[111,137],"are":[112,186],"as":[113,115],"high":[114],"20":[116],"to":[117,188],"25%.":[118],"South":[119],"country":[123,142,162],"largest":[126],"HIVinfected\\npopulation":[127],"worldwide.":[128],"With":[129],"15%":[134],"aged":[138],"over\\n15":[139],"years,":[140,155],"has":[143],"6":[145],"HIV.":[150],"Over":[151],"few":[154],"declined,":[163],"yet":[164],"incidence":[165],"remain":[167],"considerable.\\nIn":[168],"mid-2010,":[169],"1.5":[171,184],"receiving":[178],"antiretroviral":[179],"therapy\\n(ART),":[180],"while":[181],"further":[183],"be":[189],"eligible":[190],"for":[191],"treatment.":[192]},"counts_by_year":[],"updated_date":"2026-09-09T07:26:56.047234","created_date":"2016-06-24T00:00:00"}