{"id":"https://openalex.org/W2054092941","doi":"https://doi.org/10.1016/0896-6273(88)90197-3","title":"Cloning of human GAP 43: Growth association and ischemic resurgence","display_name":"Cloning of human GAP 43: Growth association and ischemic resurgence","publication_year":1988,"publication_date":"1988-04-01","ids":{"openalex":"https://openalex.org/W2054092941","doi":"https://doi.org/10.1016/0896-6273(88)90197-3","mag":"2054092941","pmid":"https://pubmed.ncbi.nlm.nih.gov/3272163"},"language":"en","primary_location":{"id":"doi:10.1016/0896-6273(88)90197-3","doi":"https://doi.org/10.1016/0896-6273(88)90197-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0896-6273(88)90197-3","pdf_url":null,"source":{"id":"https://openalex.org/S45757444","display_name":"Neuron","issn_l":"0896-6273","issn":["0896-6273","1097-4199"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuron","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030712587","display_name":"Shi\u2010Chung Ng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shi-Chung Ng","raw_affiliation_strings":["Howard Hughes Medical Institute, Massachusetts General Hospital, Boston 02114","The Howard Hughes Medical Institute Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts 02114, USA","The Medical Service Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts 02114, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Howard Hughes Medical Institute, Massachusetts General Hospital, Boston 02114","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"The Howard Hughes Medical Institute Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts 02114, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"The Medical Service Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts 02114, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014095062","display_name":"Suzanne M. de la Monte","orcid":"https://orcid.org/0000-0001-5886-2306","observed_orcids":["https://orcid.org/0000-0001-5886-2306"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Suzanne M. de la Monte","raw_affiliation_strings":["The Pathology Service Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts 02114, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Pathology Service Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts 02114, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086821606","display_name":"Gary L. Conboy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gary L. Conboy","raw_affiliation_strings":["The Howard Hughes Medical Institute Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts 02114, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Howard Hughes Medical Institute Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts 02114, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107484120","display_name":"Larry R. Karns","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Larry R. Karns","raw_affiliation_strings":["The Howard Hughes Medical Institute Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts 02114, USA","The Medical Service Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts 02114, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Howard Hughes Medical Institute Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts 02114, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"The Medical Service Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts 02114, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053276209","display_name":"Mark C. Fishman","orcid":"https://orcid.org/0000-0003-0033-541X","observed_orcids":["https://orcid.org/0000-0003-0033-541X"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark C. Fishman","raw_affiliation_strings":["The Howard Hughes Medical Institute Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts 02114, USA","The Medical Service Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts 02114, USA","The Neurology Service Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts 02114, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Howard Hughes Medical Institute Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts 02114, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"The Medical Service Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts 02114, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"The Neurology Service Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts 02114, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":10400,"currency":"USD","value_usd":10400},"apc_paid":null,"fwci":6.3601,"has_fulltext":false,"cited_by_count":152,"citation_normalized_percentile":{"value":0.97965384,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"1","issue":"2","first_page":"133","last_page":"139"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10483","display_name":"Nerve injury and regeneration","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10483","display_name":"Nerve injury and regeneration","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12061","display_name":"Axon Guidance and Neuronal Signaling","score":0.009100000374019146,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gap-43","display_name":"GAP-43","score":0.9789999723434448},{"id":"https://openalex.org/keywords/growth-associated-protein","display_name":"growth-associated protein","score":0.5989999771118164},{"id":"https://openalex.org/keywords/cdna-cloning","display_name":"cDNA cloning","score":0.9350000023841858},{"id":"https://openalex.org/keywords/growth-cones","display_name":"growth cones","score":0.6549999713897705},{"id":"https://openalex.org/keywords/axonal-elongation","display_name":"axon elongation","score":0.9620000123977661},{"id":"https://openalex.org/keywords/cns-repair","display_name":"CNS repair","score":0.5550000071525574},{"id":"https://openalex.org/keywords/ischemic-injury","display_name":"ischemic injury","score":0.7950000166893005},{"id":"https://openalex.org/keywords/neuronal-remodeling","display_name":"neuronal remodeling","score":0.4129999876022339},{"id":"https://openalex.org/keywords/postmortem-brain","display_name":"postmortem brain","score":0.6380000114440918},{"id":"https://openalex.org/keywords/newborn-brain","display_name":"neonatal brain","score":0.7310000061988831},{"id":"https://openalex.org/keywords/neurological-disorders","display_name":"neurological disorders","score":0.5690000057220459}],"concepts":[{"id":"https://openalex.org/C2777670902","wikidata":"https://www.wikidata.org/wiki/Q492038","display_name":"Human brain","level":2,"score":0.5991814732551575},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5934090614318848},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.592609703540802},{"id":"https://openalex.org/C158157758","wikidata":"https://www.wikidata.org/wiki/Q232438","display_name":"Gap junction","level":3,"score":0.5159538388252258},{"id":"https://openalex.org/C121050878","wikidata":"https://www.wikidata.org/wiki/Q5135020","display_name":"Cloning (programming)","level":2,"score":0.4623580574989319},{"id":"https://openalex.org/C90770895","wikidata":"https://www.wikidata.org/wiki/Q14906268","display_name":"Gap-43 protein","level":3,"score":0.4224960505962372},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.41105154156684875},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.2719547152519226},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.12551188468933105},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.06909173727035522},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002544","descriptor_name":"Cerebral Infarction","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002544","descriptor_name":"Cerebral Infarction","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019922","descriptor_name":"GAP-43 Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0896-6273(88)90197-3","doi":"https://doi.org/10.1016/0896-6273(88)90197-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0896-6273(88)90197-3","pdf_url":null,"source":{"id":"https://openalex.org/S45757444","display_name":"Neuron","issn_l":"0896-6273","issn":["0896-6273","1097-4199"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuron","raw_type":"journal-article"},{"id":"pmid:3272163","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3272163","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuron","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306082","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W587009204","https://openalex.org/W1518396254","https://openalex.org/W1524258826","https://openalex.org/W1555701468","https://openalex.org/W1576577565","https://openalex.org/W1587319566","https://openalex.org/W1592692300","https://openalex.org/W1764456055","https://openalex.org/W1966142934","https://openalex.org/W1974378885","https://openalex.org/W1975782461","https://openalex.org/W1992785510","https://openalex.org/W2014669590","https://openalex.org/W2024281266","https://openalex.org/W2024853323","https://openalex.org/W2025763720","https://openalex.org/W2029252387","https://openalex.org/W2032585771","https://openalex.org/W2042817456","https://openalex.org/W2045830838","https://openalex.org/W2052819504","https://openalex.org/W2057217877","https://openalex.org/W2060333964","https://openalex.org/W2062898068","https://openalex.org/W2076203826","https://openalex.org/W2078119356","https://openalex.org/W2080532845","https://openalex.org/W2083024364","https://openalex.org/W2084336840","https://openalex.org/W2086238626","https://openalex.org/W2095876128","https://openalex.org/W2118078864","https://openalex.org/W2118851646","https://openalex.org/W2123223673","https://openalex.org/W2131331811","https://openalex.org/W2138270253","https://openalex.org/W2315931805","https://openalex.org/W3215981791","https://openalex.org/W4235180161","https://openalex.org/W6666196698","https://openalex.org/W6671132182"],"related_works":["https://openalex.org/W2380577705","https://openalex.org/W2377941021","https://openalex.org/W2056424069","https://openalex.org/W2063627391","https://openalex.org/W1986953803","https://openalex.org/W2262159938","https://openalex.org/W7065814278","https://openalex.org/W3093090386","https://openalex.org/W2089640725","https://openalex.org/W2092852356"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}