{"id":"https://openalex.org/W2053787315","doi":"https://doi.org/10.1016/j.mrgentox.2004.10.005","title":"Zearalenone induces chromosome aberrations in mouse bone marrow: preventive effect of 17\u03b2-estradiol, progesterone and Vitamin E","display_name":"Zearalenone induces chromosome aberrations in mouse bone marrow: preventive effect of 17\u03b2-estradiol, progesterone and Vitamin E","publication_year":2004,"publication_date":"2004-12-21","ids":{"openalex":"https://openalex.org/W2053787315","doi":"https://doi.org/10.1016/j.mrgentox.2004.10.005","mag":"2053787315","pmid":"https://pubmed.ncbi.nlm.nih.gov/15661612"},"language":"en","primary_location":{"id":"doi:10.1016/j.mrgentox.2004.10.005","doi":"https://doi.org/10.1016/j.mrgentox.2004.10.005","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.mrgentox.2004.10.005","pdf_url":null,"source":{"id":"https://openalex.org/S29775604","display_name":"Mutation Research/Genetic Toxicology and Environmental Mutagenesis","issn_l":"1383-5718","issn":["1383-5718","1879-3592"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation Research/Genetic Toxicology and Environmental Mutagenesis","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063592205","display_name":"Zouhour Ouanes","orcid":"https://orcid.org/0000-0003-0409-3446","observed_orcids":["https://orcid.org/0000-0003-0409-3446"]},"institutions":[{"id":"https://openalex.org/I166928557","display_name":"University of Monastir","ror":"https://ror.org/00nhtcg76","country_code":"TN","type":"education","lineage":["https://openalex.org/I166928557"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Z. Ouanes","raw_affiliation_strings":["Laboratoire de Recherche sur les Substances Biologiquement Compatibles (LRSBC), Facult\u00e9 de M\u00e9decine Dentaire, Rue Avicenne, 5019 Monastir, Tunisia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Recherche sur les Substances Biologiquement Compatibles (LRSBC), Facult\u00e9 de M\u00e9decine Dentaire, Rue Avicenne, 5019 Monastir, Tunisia","institution_ids":["https://openalex.org/I166928557"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080701253","display_name":"Imen Ayed\u2010Boussema","orcid":"https://orcid.org/0000-0002-0253-6007","observed_orcids":["https://orcid.org/0000-0002-0253-6007"]},"institutions":[{"id":"https://openalex.org/I166928557","display_name":"University of Monastir","ror":"https://ror.org/00nhtcg76","country_code":"TN","type":"education","lineage":["https://openalex.org/I166928557"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"I. Ayed-Boussema","raw_affiliation_strings":["Laboratoire de Recherche sur les Substances Biologiquement Compatibles (LRSBC), Facult\u00e9 de M\u00e9decine Dentaire, Rue Avicenne, 5019 Monastir, Tunisia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Recherche sur les Substances Biologiquement Compatibles (LRSBC), Facult\u00e9 de M\u00e9decine Dentaire, Rue Avicenne, 5019 Monastir, Tunisia","institution_ids":["https://openalex.org/I166928557"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089838772","display_name":"Tarek Ba\u00e2ti","orcid":"https://orcid.org/0000-0002-6603-5615","observed_orcids":["https://orcid.org/0000-0002-6603-5615"]},"institutions":[{"id":"https://openalex.org/I166928557","display_name":"University of Monastir","ror":"https://ror.org/00nhtcg76","country_code":"TN","type":"education","lineage":["https://openalex.org/I166928557"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"T. Baati","raw_affiliation_strings":["Laboratoire de Recherche sur les Substances Biologiquement Compatibles (LRSBC), Facult\u00e9 de M\u00e9decine Dentaire, Rue Avicenne, 5019 Monastir, Tunisia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Recherche sur les Substances Biologiquement Compatibles (LRSBC), Facult\u00e9 de M\u00e9decine Dentaire, Rue Avicenne, 5019 Monastir, Tunisia","institution_ids":["https://openalex.org/I166928557"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108483112","display_name":"Edmond Eku\ufffd Creppy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I15057530","display_name":"Universit\u00e9 de Bordeaux","ror":"https://ror.org/057qpr032","country_code":"FR","type":"education","lineage":["https://openalex.org/I15057530"]},{"id":"https://openalex.org/I4405256745","display_name":"Universit\u00e9 Bordeaux Segalen","ror":"https://ror.org/04gbzm373","country_code":"FR","type":"education","lineage":["https://openalex.org/I15057530","https://openalex.org/I4405256745"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"E.E. Creppy","raw_affiliation_strings":["Laboratoire de Toxicologie et d\u2019Hygi\u00e8ne Appliqu\u00e9e, UFR des Sciences Pharmaceutiques, Universit\u00e9 Bordeaux II, 146 Rue L\u00e9o Saignat, 33076 Bordeaux-Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Toxicologie et d\u2019Hygi\u00e8ne Appliqu\u00e9e, UFR des Sciences Pharmaceutiques, Universit\u00e9 Bordeaux II, 146 Rue L\u00e9o Saignat, 33076 Bordeaux-Cedex, France","institution_ids":["https://openalex.org/I15057530","https://openalex.org/I4405256745"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045870220","display_name":"Hassen Bacha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I166928557","display_name":"University of Monastir","ror":"https://ror.org/00nhtcg76","country_code":"TN","type":"education","lineage":["https://openalex.org/I166928557"]}],"countries":["TN"],"is_corresponding":true,"raw_author_name":"H. Bacha","raw_affiliation_strings":["Laboratoire de Recherche sur les Substances Biologiquement Compatibles (LRSBC), Facult\u00e9 de M\u00e9decine Dentaire, Rue Avicenne, 5019 Monastir, Tunisia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Recherche sur les Substances Biologiquement Compatibles (LRSBC), Facult\u00e9 de M\u00e9decine Dentaire, Rue Avicenne, 5019 Monastir, Tunisia","institution_ids":["https://openalex.org/I166928557"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5045870220"],"corresponding_institution_ids":["https://openalex.org/I166928557"],"apc_list":{"value":3350,"currency":"USD","value_usd":3350},"apc_paid":null,"fwci":1.7295,"has_fulltext":false,"cited_by_count":85,"citation_normalized_percentile":{"value":0.82852807,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"565","issue":"2","first_page":"139","last_page":"149"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.8134999871253967,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.8134999871253967,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10520","display_name":"Mycotoxins in Agriculture and Food","score":0.1776999980211258,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/zearalenone","display_name":"zearalenone","score":1.0},{"id":"https://openalex.org/keywords/mycotoxins","display_name":"mycotoxins","score":0.859000027179718},{"id":"https://openalex.org/keywords/chromosomal-abnormalities","display_name":"chromosomal abnormalities","score":0.8740000128746033},{"id":"https://openalex.org/keywords/bone-marrow","display_name":"bone marrow","score":0.8949999809265137},{"id":"https://openalex.org/keywords/estradiol","display_name":"estradiol","score":0.9079999923706055},{"id":"https://openalex.org/keywords/progesterone","display_name":"progesterone","score":1.0},{"id":"https://openalex.org/keywords/vitamin-e","display_name":"vitamin E","score":0.9959999918937683},{"id":"https://openalex.org/keywords/estrogen-receptor-binding","display_name":"estrogen receptor binding","score":0.5490000247955322},{"id":"https://openalex.org/keywords/dose-fractionation","display_name":"dose fractionation","score":0.8080000281333923},{"id":"https://openalex.org/keywords/hit-and-run-mechanism","display_name":"hit-and-run mechanism","score":0.7009999752044678},{"id":"https://openalex.org/keywords/dna-damage","display_name":"DNA damage","score":0.5289999842643738},{"id":"https://openalex.org/keywords/preventive-effect","display_name":"preventive effect","score":0.335999995470047},{"id":"https://openalex.org/keywords/mice","display_name":"mice","score":0.38100001215934753}],"concepts":[{"id":"https://openalex.org/C2777140777","wikidata":"https://www.wikidata.org/wiki/Q169326","display_name":"Zearalenone","level":3,"score":0.7249413728713989},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.6027392745018005},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6004377603530884},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5947533249855042},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.5642621517181396},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.4887104034423828},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.486141175031662},{"id":"https://openalex.org/C2994296024","wikidata":"https://www.wikidata.org/wiki/Q744962","display_name":"Chromosome aberration","level":4,"score":0.4706527292728424},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4559086859226227},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.4483899474143982},{"id":"https://openalex.org/C2776940978","wikidata":"https://www.wikidata.org/wiki/Q34956","display_name":"Vitamin","level":2,"score":0.414695143699646},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.39657244086265564},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.37553223967552185},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.322115421295166},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.20898136496543884},{"id":"https://openalex.org/C84699730","wikidata":"https://www.wikidata.org/wiki/Q422449","display_name":"Mycotoxin","level":2,"score":0.1917072832584381},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.14995646476745605},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D001854","descriptor_name":"Bone Marrow Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D001854","descriptor_name":"Bone Marrow Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D001854","descriptor_name":"Bone Marrow Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002869","descriptor_name":"Chromosome Aberrations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002875","descriptor_name":"Chromosomes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D004958","descriptor_name":"Estradiol","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004958","descriptor_name":"Estradiol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004968","descriptor_name":"Estrogens, Non-Steroidal","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004968","descriptor_name":"Estrogens, Non-Steroidal","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011374","descriptor_name":"Progesterone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011374","descriptor_name":"Progesterone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014810","descriptor_name":"Vitamin E","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014810","descriptor_name":"Vitamin E","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D015025","descriptor_name":"Zearalenone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D015025","descriptor_name":"Zearalenone","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.mrgentox.2004.10.005","doi":"https://doi.org/10.1016/j.mrgentox.2004.10.005","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.mrgentox.2004.10.005","pdf_url":null,"source":{"id":"https://openalex.org/S29775604","display_name":"Mutation Research/Genetic Toxicology and Environmental Mutagenesis","issn_l":"1383-5718","issn":["1383-5718","1879-3592"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation Research/Genetic Toxicology and Environmental Mutagenesis","raw_type":"journal-article"},{"id":"pmid:15661612","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15661612","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mutation research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":56,"referenced_works":["https://openalex.org/W119748667","https://openalex.org/W204699962","https://openalex.org/W781336074","https://openalex.org/W1606965631","https://openalex.org/W1967663993","https://openalex.org/W1969643309","https://openalex.org/W1973986846","https://openalex.org/W1976484847","https://openalex.org/W1977009097","https://openalex.org/W1977547986","https://openalex.org/W1980781068","https://openalex.org/W1982561147","https://openalex.org/W1985976644","https://openalex.org/W2004063498","https://openalex.org/W2013364428","https://openalex.org/W2020625939","https://openalex.org/W2029062824","https://openalex.org/W2031850603","https://openalex.org/W2034877837","https://openalex.org/W2036436529","https://openalex.org/W2037448330","https://openalex.org/W2039031803","https://openalex.org/W2045374777","https://openalex.org/W2048883010","https://openalex.org/W2051280057","https://openalex.org/W2053412904","https://openalex.org/W2058386093","https://openalex.org/W2064637938","https://openalex.org/W2066721336","https://openalex.org/W2073785368","https://openalex.org/W2075218568","https://openalex.org/W2076406046","https://openalex.org/W2078293038","https://openalex.org/W2082895579","https://openalex.org/W2084586277","https://openalex.org/W2088230515","https://openalex.org/W2091403567","https://openalex.org/W2093967771","https://openalex.org/W2095030337","https://openalex.org/W2095619460","https://openalex.org/W2096220241","https://openalex.org/W2102113274","https://openalex.org/W2102226960","https://openalex.org/W2133164739","https://openalex.org/W2134528790","https://openalex.org/W2139324170","https://openalex.org/W2152806277","https://openalex.org/W2156313802","https://openalex.org/W2162460589","https://openalex.org/W2164234987","https://openalex.org/W2165197441","https://openalex.org/W2271833728","https://openalex.org/W2404590947","https://openalex.org/W2413184801","https://openalex.org/W2415889720","https://openalex.org/W2418388321"],"related_works":["https://openalex.org/W2102226960","https://openalex.org/W2133164739","https://openalex.org/W1975475278","https://openalex.org/W1980414039","https://openalex.org/W2031850603","https://openalex.org/W2051412989","https://openalex.org/W2048883010","https://openalex.org/W2156581784","https://openalex.org/W2462910504","https://openalex.org/W2033973743"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}