{"id":"https://openalex.org/W2053650425","doi":"https://doi.org/10.1016/s0006-291x(74)80420-1","title":"Evidence for glucocorticoid transport through the target cell membrane","display_name":"Evidence for glucocorticoid transport through the target cell membrane","publication_year":1974,"publication_date":"1974-12-01","ids":{"openalex":"https://openalex.org/W2053650425","doi":"https://doi.org/10.1016/s0006-291x(74)80420-1","mag":"2053650425","pmid":"https://pubmed.ncbi.nlm.nih.gov/4376007"},"language":"en","primary_location":{"id":"doi:10.1016/s0006-291x(74)80420-1","doi":"https://doi.org/10.1016/s0006-291x(74)80420-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0006-291x(74)80420-1","pdf_url":null,"source":{"id":"https://openalex.org/S151589183","display_name":"Biochemical and Biophysical Research Communications","issn_l":"0006-291X","issn":["0006-291X","1090-2104"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and Biophysical Research Communications","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081553619","display_name":"Robert W. Harrison","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert W. Harrison","raw_affiliation_strings":["Department of Medicine and Cancer Research Center Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Cancer Research Center Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111449551","display_name":"Sandra J. Fairfield","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sandra Fairfield","raw_affiliation_strings":["Department of Medicine and Cancer Research Center Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Cancer Research Center Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005244410","display_name":"David N. Orth","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David N. Orth","raw_affiliation_strings":["Department of Medicine and Cancer Research Center Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine and Cancer Research Center Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA","institution_ids":["https://openalex.org/I200719446"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I200719446"],"apc_list":{"value":3110,"currency":"USD","value_usd":3110},"apc_paid":null,"fwci":1.1329,"has_fulltext":false,"cited_by_count":41,"citation_normalized_percentile":{"value":0.73566731,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"61","issue":"4","first_page":"1262","last_page":"1267"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.4684999883174896,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.4684999883174896,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.43950000405311584,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.04659999907016754,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/steroid-uptake","display_name":"steroid uptake","score":0.8700000047683716},{"id":"https://openalex.org/keywords/plasma-membrane","display_name":"plasma membrane","score":0.7509999871253967},{"id":"https://openalex.org/keywords/sialic-acid","display_name":"sialic acid","score":0.9020000100135803},{"id":"https://openalex.org/keywords/neuraminidase","display_name":"neuraminidase","score":0.9449999928474426},{"id":"https://openalex.org/keywords/phospholipase-a2","display_name":"phospholipase A2","score":0.9900000095367432},{"id":"https://openalex.org/keywords/protease","display_name":"proteolytic enzymes","score":0.9190000295639038},{"id":"https://openalex.org/keywords/membrane-structure","display_name":"membrane structure","score":0.4129999876022339}],"concepts":[{"id":"https://openalex.org/C98539663","wikidata":"https://www.wikidata.org/wiki/Q220599","display_name":"Cytosol","level":3,"score":0.7779794335365295},{"id":"https://openalex.org/C134164806","wikidata":"https://www.wikidata.org/wiki/Q409485","display_name":"Neuraminidase","level":3,"score":0.6363160014152527},{"id":"https://openalex.org/C2780841215","wikidata":"https://www.wikidata.org/wiki/Q422549","display_name":"Glucocorticoid","level":2,"score":0.6256883144378662},{"id":"https://openalex.org/C2778106830","wikidata":"https://www.wikidata.org/wiki/Q29548","display_name":"Cell membrane","level":3,"score":0.5719010829925537},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.5712093710899353},{"id":"https://openalex.org/C3019223276","wikidata":"https://www.wikidata.org/wiki/Q212410","display_name":"Proteolytic enzymes","level":3,"score":0.5571340918540955},{"id":"https://openalex.org/C2776551241","wikidata":"https://www.wikidata.org/wiki/Q24768001","display_name":"Phospholipase A2","level":3,"score":0.5546942353248596},{"id":"https://openalex.org/C2780115458","wikidata":"https://www.wikidata.org/wiki/Q419311","display_name":"Sialic acid","level":2,"score":0.5504157543182373},{"id":"https://openalex.org/C59493245","wikidata":"https://www.wikidata.org/wiki/Q14877410","display_name":"Glucocorticoid receptor","level":3,"score":0.5432617664337158},{"id":"https://openalex.org/C73695083","wikidata":"https://www.wikidata.org/wiki/Q409485","display_name":"Sialidase","level":4,"score":0.5140060186386108},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.4916606545448303},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4891953468322754},{"id":"https://openalex.org/C12927208","wikidata":"https://www.wikidata.org/wiki/Q210430","display_name":"Phospholipase","level":3,"score":0.4159366488456726},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3980533480644226},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3835506737232208},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.36454933881759644},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3413538932800293},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.1620943546295166}],"mesh":[{"descriptor_ui":"D001693","descriptor_name":"Biological Transport, Active","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003600","descriptor_name":"Cytosol","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003907","descriptor_name":"Dexamethasone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009439","descriptor_name":"Neuraminidase","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D010447","descriptor_name":"Peptide Hydrolases","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D010740","descriptor_name":"Phospholipases","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011956","descriptor_name":"Receptors, Cell Surface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014222","descriptor_name":"Triamcinolone Acetonide","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0006-291x(74)80420-1","doi":"https://doi.org/10.1016/s0006-291x(74)80420-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0006-291x(74)80420-1","pdf_url":null,"source":{"id":"https://openalex.org/S151589183","display_name":"Biochemical and Biophysical Research Communications","issn_l":"0006-291X","issn":["0006-291X","1090-2104"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and Biophysical Research Communications","raw_type":"journal-article"},{"id":"pmid:4376007","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4376007","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and biophysical research communications","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1968127547","https://openalex.org/W1991655565","https://openalex.org/W1993474219","https://openalex.org/W2024001544","https://openalex.org/W2035874254","https://openalex.org/W2069847692","https://openalex.org/W2093693099","https://openalex.org/W2399889170"],"related_works":["https://openalex.org/W2037953453","https://openalex.org/W2061090948","https://openalex.org/W2063773484","https://openalex.org/W1994216344","https://openalex.org/W304121671","https://openalex.org/W2043771799","https://openalex.org/W1548261214","https://openalex.org/W2075082517","https://openalex.org/W2591973176","https://openalex.org/W2064810700"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}