{"id":"https://openalex.org/W2053533249","doi":"https://doi.org/10.1021/bi00482a006","title":"Electron nuclear double resonance (ENDOR) of the Qc.cntdot.- ubisemiquinone radical in the mitochondrial electron transport chain","display_name":"Electron nuclear double resonance (ENDOR) of the Qc.cntdot.- ubisemiquinone radical in the mitochondrial electron transport chain","publication_year":1990,"publication_date":"1990-07-31","ids":{"openalex":"https://openalex.org/W2053533249","doi":"https://doi.org/10.1021/bi00482a006","mag":"2053533249","pmid":"https://pubmed.ncbi.nlm.nih.gov/2171637"},"language":"en","primary_location":{"id":"doi:10.1021/bi00482a006","doi":"https://doi.org/10.1021/bi00482a006","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bi00482a006","pdf_url":null,"source":{"id":"https://openalex.org/S104038378","display_name":"Biochemistry","issn_l":"0006-2960","issn":["0006-2960","1520-4995","1943-295X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111541756","display_name":"John C. Salerno","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165799507","display_name":"Rensselaer Polytechnic Institute","ror":"https://ror.org/01rtyzb94","country_code":"US","type":"education","lineage":["https://openalex.org/I165799507"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John C. Salerno","raw_affiliation_strings":["Department of Biology, Rensselaer Polytechnic Institute, Troy, New York 12180"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Rensselaer Polytechnic Institute, Troy, New York 12180","institution_ids":["https://openalex.org/I165799507"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005957352","display_name":"Marcy P. Osgood","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marcy Osgood","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100449869","display_name":"Ya\u2010Jun Liu","orcid":"https://orcid.org/0000-0001-8761-5339","observed_orcids":["https://orcid.org/0000-0001-8761-5339"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yajun Liu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Harold Taylor","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Harold Taylor","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5012942751","display_name":"Charles P. Scholes","orcid":"https://orcid.org/0000-0003-0691-456X","observed_orcids":["https://orcid.org/0000-0003-0691-456X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Charles P. Scholes","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":0.8552,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.71599955,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"29","issue":"30","first_page":"6987","last_page":"6993"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13012","display_name":"Coenzyme Q10 studies and effects","score":0.4458000063896179,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13012","display_name":"Coenzyme Q10 studies and effects","score":0.4458000063896179,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12381","display_name":"Electron Spin Resonance Studies","score":0.3163999915122986,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.08340000361204147,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mitochondrial-electron-transport-chain","display_name":"mitochondrial electron transport chain","score":0.9229999780654907},{"id":"https://openalex.org/keywords/hydrogen-bonding","display_name":"hydrogen bonding","score":0.7179999947547913},{"id":"https://openalex.org/keywords/hyperfine-interaction","display_name":"hyperfine interaction","score":0.8109999895095825},{"id":"https://openalex.org/keywords/exchangeable-protons","display_name":"exchangeable protons","score":0.6740000247955322},{"id":"https://openalex.org/keywords/solvent-accessibility","display_name":"solvent accessibility","score":0.5350000262260437}],"concepts":[{"id":"https://openalex.org/C2776370595","wikidata":"https://www.wikidata.org/wiki/Q3955012","display_name":"Semiquinone","level":3,"score":0.7934812307357788},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7451397180557251},{"id":"https://openalex.org/C65154329","wikidata":"https://www.wikidata.org/wiki/Q1327024","display_name":"Electron nuclear double resonance","level":3,"score":0.6511560082435608},{"id":"https://openalex.org/C131538251","wikidata":"https://www.wikidata.org/wiki/Q1413102","display_name":"Hyperfine structure","level":2,"score":0.6092860102653503},{"id":"https://openalex.org/C2780643102","wikidata":"https://www.wikidata.org/wiki/Q412382","display_name":"Quinone","level":2,"score":0.553663432598114},{"id":"https://openalex.org/C187961010","wikidata":"https://www.wikidata.org/wiki/Q260463","display_name":"Electron paramagnetic resonance","level":2,"score":0.5052476525306702},{"id":"https://openalex.org/C24840226","wikidata":"https://www.wikidata.org/wiki/Q211016","display_name":"Electron transport chain","level":2,"score":0.49687984585762024},{"id":"https://openalex.org/C139210041","wikidata":"https://www.wikidata.org/wiki/Q2145840","display_name":"Resonance (particle physics)","level":2,"score":0.48509347438812256},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.45400121808052063},{"id":"https://openalex.org/C2780768313","wikidata":"https://www.wikidata.org/wiki/Q408068","display_name":"Cytochrome","level":3,"score":0.42604944109916687},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.34554293751716614},{"id":"https://openalex.org/C75473681","wikidata":"https://www.wikidata.org/wiki/Q188651","display_name":"Photochemistry","level":1,"score":0.33971208333969116},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.29460644721984863},{"id":"https://openalex.org/C184779094","wikidata":"https://www.wikidata.org/wiki/Q26383","display_name":"Atomic physics","level":1,"score":0.13951081037521362},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.11663955450057983},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.08932968974113464},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07937246561050415}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003067","descriptor_name":"Coenzymes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004578","descriptor_name":"Electron Spin Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004579","descriptor_name":"Electron Transport","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005609","descriptor_name":"Free Radicals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006860","descriptor_name":"Hydrogen Bonding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008929","descriptor_name":"Mitochondria, Heart","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014451","descriptor_name":"Ubiquinone","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D014451","descriptor_name":"Ubiquinone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014451","descriptor_name":"Ubiquinone","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1021/bi00482a006","doi":"https://doi.org/10.1021/bi00482a006","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bi00482a006","pdf_url":null,"source":{"id":"https://openalex.org/S104038378","display_name":"Biochemistry","issn_l":"0006-2960","issn":["0006-2960","1520-4995","1943-295X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"journal-article"},{"id":"pmid:2171637","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2171637","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1474966174","display_name":"ELECTRON TRANSPORT &ENERGY CONSERVATION IN MITOCHONDRIA","funder_award_id":"5r01gm034306-03","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2271313675","display_name":null,"funder_award_id":"GM-35103","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G2825960364","display_name":"EPR AND ENDOR OF PARAMAGNETIC BIOMOLECULES","funder_award_id":"5r01gm035103-28","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G336008063","display_name":null,"funder_award_id":"GM-34306","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G5733973773","display_name":null,"funder_award_id":"RR 0712221","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W56280480","https://openalex.org/W1482087680","https://openalex.org/W1501872364","https://openalex.org/W1551647197","https://openalex.org/W1554679408","https://openalex.org/W1578527572","https://openalex.org/W1870394013","https://openalex.org/W1970312228","https://openalex.org/W1974761787","https://openalex.org/W1976690956","https://openalex.org/W1979803415","https://openalex.org/W1987148639","https://openalex.org/W2004400679","https://openalex.org/W2011890814","https://openalex.org/W2027460541","https://openalex.org/W2029664531","https://openalex.org/W2036730860","https://openalex.org/W2041062772","https://openalex.org/W2065510140","https://openalex.org/W2068276476","https://openalex.org/W2070603664","https://openalex.org/W2088176444","https://openalex.org/W2092978809","https://openalex.org/W2094364880","https://openalex.org/W2372533649","https://openalex.org/W3004630159"],"related_works":["https://openalex.org/W2093884442","https://openalex.org/W2052721805","https://openalex.org/W1977596894","https://openalex.org/W1548394531","https://openalex.org/W2783920081","https://openalex.org/W1551647197","https://openalex.org/W1987148639","https://openalex.org/W2025495821","https://openalex.org/W2418755576","https://openalex.org/W2087634152"],"abstract_inverted_index":{"We":[0,40],"present":[1],"an":[2],"electron":[3,31],"nuclear":[4],"double":[5],"resonance":[6,33],"(ENDOR)":[7],"study":[8],"of":[9,82,101,136],"the":[10,15,53,67,79,83,87,102,137,141],"bound":[11,84],"Qc.-":[12],"ubisemiquinone":[13],"in":[14,65,71,77,86],"mitochondrial":[16,88],"quinol":[17,89],"cytochrome":[18,90],"c":[19,91],"reductase":[20,92],"complex.":[21,93],"An":[22],"ENDOR":[23,95,129],"probe":[24],"specifically":[25],"modified":[26],"for":[27,37],"insertion":[28],"into":[29],"our":[30],"paramagnetic":[32],"cavity":[34],"was":[35,127],"used":[36],"this":[38],"study.":[39],"observed":[41],"strongly":[42],"hyperfine-coupled":[43],"protons":[44,100,110,125],"whose":[45],"exchangeable":[46,124],"nature":[47],"indicated":[48],"they":[49],"were":[50,97],"hydrogen-bonded":[51],"to":[52,69,99,107,131,140],"quinone":[54,103],"oxygen(s).":[55],"It":[56],"is":[57],"thought":[58],"that":[59,111],"such":[60],"hydrogen":[61],"bonds":[62],"are":[63],"critical":[64],"binding":[66],"ubiquinone":[68,85,138],"protein,":[70],"stabilizing":[72],"its":[73],"semiquinone":[74],"form,":[75],"and":[76,106,134],"modulating":[78],"thermodynamic":[80],"properties":[81],"Additional":[94],"features":[96],"assigned":[98],"ring":[104],"itself":[105],"weakly":[108,121],"coupled":[109],"may":[112],"be":[113],"associated":[114],"with":[115],"nearby":[116],"amino":[117],"acids.":[118],"From":[119],"very":[120],"hyperfine-coupled,":[122],"distant,":[123],"there":[126],"also":[128],"evidence":[130],"suggest":[132],"proximity":[133],"accessibility":[135],"site":[139],"solvent.":[142]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}