{"id":"https://openalex.org/W2053425799","doi":"https://doi.org/10.1016/j.bbmt.2007.12.405","title":"395: Impact of Donor T Cells on B Cell Development after Hematopoietic Cell Transplantation: Lessons from B Cell Deficient Mice","display_name":"395: Impact of Donor T Cells on B Cell Development after Hematopoietic Cell Transplantation: Lessons from B Cell Deficient Mice","publication_year":2008,"publication_date":"2008-01-28","ids":{"openalex":"https://openalex.org/W2053425799","doi":"https://doi.org/10.1016/j.bbmt.2007.12.405","mag":"2053425799"},"language":"en","primary_location":{"id":"doi:10.1016/j.bbmt.2007.12.405","doi":"https://doi.org/10.1016/j.bbmt.2007.12.405","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2007.12.405","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.bbmt.2007.12.405","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025125007","display_name":"Antonia M. S. M\u00fcller","orcid":"https://orcid.org/0000-0003-4420-9466","observed_orcids":["https://orcid.org/0000-0003-4420-9466"]},"institutions":[{"id":"https://openalex.org/I2801240073","display_name":"University Medical Center Freiburg","ror":"https://ror.org/03vzbgh69","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2801240073"]},{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"A.M.S. Mueller","raw_affiliation_strings":["Stanford School of Medicine, Stanford, CA","University Medical Center, Freiburg i.Br., Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford School of Medicine, Stanford, CA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"raw_affiliation_string":"University Medical Center, Freiburg i.Br., Germany","institution_ids":["https://openalex.org/I2801240073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085911458","display_name":"Jessica A. Allen","orcid":"https://orcid.org/0000-0001-6668-4845","observed_orcids":["https://orcid.org/0000-0001-6668-4845"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.A. Allen","raw_affiliation_strings":["Stanford School of Medicine, Stanford, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford School of Medicine, Stanford, CA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081926380","display_name":"David Bernard Miklos","orcid":"https://orcid.org/0000-0003-0717-4305","observed_orcids":["https://orcid.org/0000-0003-0717-4305"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. Miklos","raw_affiliation_strings":["Stanford School of Medicine, Stanford, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford School of Medicine, Stanford, CA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007628939","display_name":"James W. Tung","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.W. Tung","raw_affiliation_strings":["Stanford School of Medicine, Stanford, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford School of Medicine, Stanford, CA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012590130","display_name":"Judith A. Shizuru","orcid":"https://orcid.org/0000-0003-3246-4726","observed_orcids":["https://orcid.org/0000-0003-3246-4726"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.A. Shizuru","raw_affiliation_strings":["Stanford School of Medicine, Stanford, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stanford School of Medicine, Stanford, CA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3650,"currency":"USD","value_usd":3650},"apc_paid":{"value":3650,"currency":"USD","value_usd":3650},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.14408275,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":"2","first_page":"143","last_page":"144"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/donor-t-cells","display_name":"donor T cells","score":0.9279999732971191},{"id":"https://openalex.org/keywords/b-cell-development","display_name":"B cell development","score":0.9779999852180481},{"id":"https://openalex.org/keywords/b-cell-lymphopenia","display_name":"B-cell lymphopenia","score":0.7860000133514404},{"id":"https://openalex.org/keywords/hematopoietic-stem-cell-transplantation","display_name":"hematopoietic stem cell transplantation","score":0.8859999775886536},{"id":"https://openalex.org/keywords/graft-versus-host-disease","display_name":"graft-versus-host disease","score":0.9850000143051147},{"id":"https://openalex.org/keywords/b-cell-deficiency","display_name":"B cell deficiency","score":0.7300000190734863},{"id":"https://openalex.org/keywords/donor-chimerism","display_name":"donor chimerism","score":0.7419999837875366},{"id":"https://openalex.org/keywords/b-cell-reconstitution","display_name":"B cell reconstitution","score":0.6000000238418579},{"id":"https://openalex.org/keywords/cd4-t-cells","display_name":"CD4+ T cells","score":0.6520000100135803},{"id":"https://openalex.org/keywords/cd8-t-cells","display_name":"CD8+ T cells","score":0.890999972820282},{"id":"https://openalex.org/keywords/splenocytes","display_name":"splenocytes","score":0.5529999732971191}],"concepts":[{"id":"https://openalex.org/C2779193416","wikidata":"https://www.wikidata.org/wiki/Q3240226","display_name":"Syngenic","level":3,"score":0.8246303796768188},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.6684141159057617},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.6657053828239441},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.6108300685882568},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5906078815460205},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.547181248664856},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4978809356689453},{"id":"https://openalex.org/C2777408962","wikidata":"https://www.wikidata.org/wiki/Q1128050","display_name":"Hematopoietic stem cell transplantation","level":3,"score":0.48547080159187317},{"id":"https://openalex.org/C189976730","wikidata":"https://www.wikidata.org/wiki/Q3493700","display_name":"Splenocyte","level":3,"score":0.419760137796402},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.41710615158081055},{"id":"https://openalex.org/C2780931953","wikidata":"https://www.wikidata.org/wiki/Q9371","display_name":"Spleen","level":2,"score":0.3785688281059265},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3394973576068878},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.31345057487487793},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.30278390645980835},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.26426899433135986},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.12757021188735962},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.09659281373023987}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.bbmt.2007.12.405","doi":"https://doi.org/10.1016/j.bbmt.2007.12.405","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2007.12.405","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.bbmt.2007.12.405","doi":"https://doi.org/10.1016/j.bbmt.2007.12.405","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2007.12.405","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2570561589","https://openalex.org/W2585193261","https://openalex.org/W2981181949","https://openalex.org/W2135262841","https://openalex.org/W2589065937","https://openalex.org/W2980440279","https://openalex.org/W2979864978","https://openalex.org/W1970068943","https://openalex.org/W2038697962","https://openalex.org/W2346824432"],"abstract_inverted_index":{"Allogeneic":[0],"hematopoietic":[1,42],"cell":[2,9],"transplant":[3],"(HCT)":[4],"recipients":[5],"often":[6],"exhibit":[7],"B":[8,36],"(BC)":[10],"lymphopenia":[11],"due,":[12],"in":[13],"part,":[14],"to":[15],"graft-versus-host-disease":[16],"(GVHD).":[17],"Here,":[18],"we":[19],"studied":[20],"the":[21],"influence":[22],"of":[23,51,75],"donor":[24,92],"T":[25],"cells":[26,44],"(TC)":[27],"on":[28],"BC":[29,70],"deficiency":[30],"post-HCT.":[31],"Following":[32],"lethal":[33],"irradiation,":[34],"BALB.":[35],"mice":[37],"were":[38,68],"given":[39],"FACS":[40],"purified":[41],"stem":[43],"(HSC:":[45],"cKIT+Thy1.1loLin-Sca-1+)":[46],"alone,":[47],"or":[48,56],"with":[49],"co-transfer":[50],"whole":[52],"splenocytes":[53],"(SP),":[54],"CD4":[55],"CD8":[57],"TCs":[58],"from":[59],"minor":[60],"antigen-mismatched":[61],"C57BL/6":[62],"(B6)":[63],"mice.":[64],"When":[65],"pure":[66],"HSC":[67],"transplanted,":[69],"reconstituted":[71],"promptly":[72],"(median":[73],"33%":[74],"lymphocytes":[76],"[d30];":[77],"61%":[78],"[d60];":[79],"74%":[80],"[d90]),":[81],"whereas":[82],"TC":[83],"engraftment":[84],"was":[85],"retarded":[86],"and":[87],"did":[88],"not":[89],"achieve":[90],"full":[91],"chimerism.":[93]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2016-06-24T00:00:00"}