{"id":"https://openalex.org/W2053371271","doi":"https://doi.org/10.3109/00365529309103137","title":"Intestinal Metaplasia, Not Atrophy or Achlorhydria, Creates a Hostile Environment for Helicobacter pylori","display_name":"Intestinal Metaplasia, Not Atrophy or Achlorhydria, Creates a Hostile Environment for Helicobacter pylori","publication_year":1993,"publication_date":"1993-01-01","ids":{"openalex":"https://openalex.org/W2053371271","doi":"https://doi.org/10.3109/00365529309103137","mag":"2053371271","pmid":"https://pubmed.ncbi.nlm.nih.gov/8266024"},"language":"en","primary_location":{"id":"doi:10.3109/00365529309103137","doi":"https://doi.org/10.3109/00365529309103137","is_oa":false,"landing_page_url":"https://doi.org/10.3109/00365529309103137","pdf_url":null,"source":{"id":"https://openalex.org/S55592950","display_name":"Scandinavian Journal of Gastroenterology","issn_l":"0036-5521","issn":["0036-5521","1502-7708"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scandinavian Journal of Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063972548","display_name":"Robert M. Genta","orcid":"https://orcid.org/0000-0001-9482-4163","observed_orcids":["https://orcid.org/0000-0001-9482-4163"]},"institutions":[{"id":"https://openalex.org/I1322918889","display_name":"United States Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. M. Genta","raw_affiliation_strings":["Dept. of Pathology, Veterans Affairs Medical Center, Houston, TX 77030","Baylor College of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Pathology, Veterans Affairs Medical Center, Houston, TX 77030","institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]},{"raw_affiliation_string":"Baylor College of Medicine","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053556585","display_name":"David Yates Graham","orcid":"https://orcid.org/0000-0002-6908-8317","observed_orcids":["https://orcid.org/0000-0002-6908-8317"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. Y. Graham","raw_affiliation_strings":["Depts. of Pathology, Medicine, and Molecular Virology, Veterans Affairs Medical Center, and Baylor College of Medicine, Houston, Texas, USA","Baylor College of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Depts. of Pathology, Medicine, and Molecular Virology, Veterans Affairs Medical Center, and Baylor College of Medicine, Houston, Texas, USA","institution_ids":["https://openalex.org/I181547552","https://openalex.org/I2799886695"]},{"raw_affiliation_string":"Baylor College of Medicine","institution_ids":["https://openalex.org/I181547552"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9013,"has_fulltext":false,"cited_by_count":38,"citation_normalized_percentile":{"value":0.7566528,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"28","issue":"10","first_page":"924","last_page":"928"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11855","display_name":"Gastrointestinal disorders and treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/helicobacter-pylori","display_name":"Helicobacter pylori","score":0.9309999942779541},{"id":"https://openalex.org/keywords/intestinal-metaplasia","display_name":"intestinal metaplasia","score":0.9679999947547913},{"id":"https://openalex.org/keywords/atrophic-gastritis","display_name":"atrophic gastritis","score":0.9430000185966492},{"id":"https://openalex.org/keywords/achlorhydria","display_name":"achlorhydria","score":0.9369999766349792},{"id":"https://openalex.org/keywords/hyperplastic-gastric-polyps","display_name":"gastric hyperplastic polyps","score":0.9490000009536743},{"id":"https://openalex.org/keywords/helicobacter-pylori-eradication","display_name":"Helicobacter pylori eradication","score":0.824999988079071},{"id":"https://openalex.org/keywords/triple-therapy","display_name":"triple therapy","score":0.8259999752044678},{"id":"https://openalex.org/keywords/gastric-acid","display_name":"gastric acid","score":0.47600001096725464},{"id":"https://openalex.org/keywords/neutrophil-infiltration","display_name":"neutrophil infiltration","score":0.9169999957084656},{"id":"https://openalex.org/keywords/dyspepsia","display_name":"dyspepsia","score":0.824999988079071}],"concepts":[{"id":"https://openalex.org/C2776409635","wikidata":"https://www.wikidata.org/wiki/Q180556","display_name":"Helicobacter pylori","level":2,"score":0.8512170314788818},{"id":"https://openalex.org/C2776497702","wikidata":"https://www.wikidata.org/wiki/Q872095","display_name":"Intestinal metaplasia","level":3,"score":0.7957583665847778},{"id":"https://openalex.org/C2779970781","wikidata":"https://www.wikidata.org/wiki/Q340548","display_name":"Achlorhydria","level":3,"score":0.7302297353744507},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.6844596862792969},{"id":"https://openalex.org/C2780342937","wikidata":"https://www.wikidata.org/wiki/Q1826391","display_name":"Atrophic gastritis","level":4,"score":0.6486413478851318},{"id":"https://openalex.org/C2778677798","wikidata":"https://www.wikidata.org/wiki/Q183130","display_name":"Gastritis","level":3,"score":0.6181559562683105},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6080548167228699},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6018134355545044},{"id":"https://openalex.org/C2781172350","wikidata":"https://www.wikidata.org/wiki/Q194520","display_name":"Atrophy","level":2,"score":0.5514954328536987},{"id":"https://openalex.org/C2780832600","wikidata":"https://www.wikidata.org/wiki/Q134684","display_name":"Helicobacter","level":3,"score":0.5127502679824829},{"id":"https://openalex.org/C2908781503","wikidata":"https://www.wikidata.org/wiki/Q15992384","display_name":"Hyperplastic Polyp","level":5,"score":0.5006551742553711},{"id":"https://openalex.org/C2779422922","wikidata":"https://www.wikidata.org/wiki/Q1029907","display_name":"Stomach","level":2,"score":0.49371299147605896},{"id":"https://openalex.org/C2779357193","wikidata":"https://www.wikidata.org/wiki/Q660713","display_name":"Metaplasia","level":2,"score":0.46665167808532715},{"id":"https://openalex.org/C90378955","wikidata":"https://www.wikidata.org/wiki/Q5476344","display_name":"Foveolar cell","level":4,"score":0.46392759680747986},{"id":"https://openalex.org/C2781443798","wikidata":"https://www.wikidata.org/wiki/Q383249","display_name":"Gastric mucosa","level":3,"score":0.42726439237594604},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3844013214111328},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.1893177032470703},{"id":"https://openalex.org/C2778435480","wikidata":"https://www.wikidata.org/wiki/Q840387","display_name":"Colonoscopy","level":4,"score":0.0602203905582428},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000126","descriptor_name":"Achlorhydria","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001284","descriptor_name":"Atrophy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005756","descriptor_name":"Gastritis","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D005756","descriptor_name":"Gastritis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007422","descriptor_name":"Intestines","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D007422","descriptor_name":"Intestines","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008679","descriptor_name":"Metaplasia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013270","descriptor_name":"Stomach","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D016480","descriptor_name":"Helicobacter pylori","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016481","descriptor_name":"Helicobacter Infections","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.3109/00365529309103137","doi":"https://doi.org/10.3109/00365529309103137","is_oa":false,"landing_page_url":"https://doi.org/10.3109/00365529309103137","pdf_url":null,"source":{"id":"https://openalex.org/S55592950","display_name":"Scandinavian Journal of Gastroenterology","issn_l":"0036-5521","issn":["0036-5521","1502-7708"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scandinavian Journal of Gastroenterology","raw_type":"journal-article"},{"id":"pmid:8266024","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8266024","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scandinavian journal of gastroenterology","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[{"id":"https://openalex.org/G2333443507","display_name":"CAMPYLOBACTER PYLORIDIS IN GASTRODUODENAL DISEASE","funder_award_id":"5r01dk039919-02","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2802873031","display_name":null,"funder_award_id":"DK39919","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W164051564","https://openalex.org/W1584376896","https://openalex.org/W2007382422","https://openalex.org/W2041598388","https://openalex.org/W2151667645","https://openalex.org/W2153181230","https://openalex.org/W2162873914","https://openalex.org/W4210953636"],"related_works":["https://openalex.org/W2394883723","https://openalex.org/W2400151955","https://openalex.org/W2400597137","https://openalex.org/W2163792620","https://openalex.org/W2059363101","https://openalex.org/W2004327364","https://openalex.org/W2381751236","https://openalex.org/W2082821215","https://openalex.org/W2340727949","https://openalex.org/W2374944179"],"abstract_inverted_index":{"A":[0],"54-year-old":[1],"man":[2],"with":[3,28,83],"dyspepsia,":[4],"Helicobacter":[5],"pylori-associated":[6],"chronic":[7],"active":[8],"atrophic":[9,99],"gastritis":[10,100],"without":[11],"intestinal":[12,75],"metaplasia,":[13,76],"and":[14,34,58,106],"hyperplastic":[15,112],"gastric":[16,31,35,56,84],"polyps":[17,62,113],"was":[18],"followed":[19],"up":[20],"for":[21],"1":[22],"year":[23],"after":[24],"H.":[25,40,77,94,120],"pylori":[26,41,78,95],"eradication":[27],"sequential":[29],"endoscopic":[30],"mucosal":[32],"mapping":[33],"function":[36],"tests.":[37],"Eradication":[38],"of":[39,50,60,74,89,116,119],"by":[42],"triple":[43],"therapy":[44],"resulted":[45],"in":[46,71,111],"the":[47,53,61,72,81,87,108,117],"histologic":[48],"resolution":[49],"gastritis.":[51],"However,":[52],"patient's":[54],"condition,":[55],"function,":[57],"morphology":[59],"were":[63],"not":[64,92],"affected.":[65],"This":[66],"case":[67],"illustrates":[68],"that:":[69],"a)":[70],"absence":[73,88],"can":[79],"infect":[80],"stomach":[82],"atrophy;":[85],"b)":[86],"acid":[90],"does":[91],"preclude":[93],"infection;":[96],"c)":[97],"advanced":[98],"may":[101],"be":[102],"an":[103],"irreversible":[104],"condition;":[105],"(d)":[107],"neutrophilic":[109],"infiltrate":[110],"is":[114],"independent":[115],"presence":[118],"pylori.":[121]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}