{"id":"https://openalex.org/W2053064795","doi":"https://doi.org/10.1073/pnas.0700733104","title":"Bacterial superantigen facilitates epithelial presentation of allergen to T helper 2 cells","display_name":"Bacterial superantigen facilitates epithelial presentation of allergen to T helper 2 cells","publication_year":2007,"publication_date":"2007-03-19","ids":{"openalex":"https://openalex.org/W2053064795","doi":"https://doi.org/10.1073/pnas.0700733104","mag":"2053064795","pmid":"https://pubmed.ncbi.nlm.nih.gov/17372219","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1838460"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.0700733104","doi":"https://doi.org/10.1073/pnas.0700733104","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.0700733104","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1838460/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027137275","display_name":"Michael R. Ardern\u2010Jones","orcid":"https://orcid.org/0000-0003-1466-2016","observed_orcids":["https://orcid.org/0000-0003-1466-2016"]},"institutions":[{"id":"https://openalex.org/I2801179840","display_name":"Churchill Hospital","ror":"https://ror.org/009vheq40","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801179840","https://openalex.org/I4210147381"]},{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4210110594","display_name":"MRC Weatherall Institute of Molecular Medicine","ror":"https://ror.org/01q496a73","country_code":"GB","type":"facility","lineage":["https://openalex.org/I40120149","https://openalex.org/I4210087105","https://openalex.org/I4210110594","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I4210124851","display_name":"MRC Human Immunology Unit","ror":"https://ror.org/02kcpr174","country_code":"GB","type":"facility","lineage":["https://openalex.org/I40120149","https://openalex.org/I4210087105","https://openalex.org/I4210110594","https://openalex.org/I4210124851","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I90344618","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Michael R. Ardern-Jones","raw_affiliation_strings":["Department of Dermatology, Churchill Hospital, Old Road, Oxford OX3 7LJ, United Kingdom","Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Churchill Hospital, Old Road, Oxford OX3 7LJ, United Kingdom","institution_ids":["https://openalex.org/I2801179840"]},{"raw_affiliation_string":"Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom; and","institution_ids":["https://openalex.org/I40120149","https://openalex.org/I4210110594","https://openalex.org/I4210124851","https://openalex.org/I90344618"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091250160","display_name":"Antony P. Black","orcid":"https://orcid.org/0000-0003-0579-0702","observed_orcids":["https://orcid.org/0000-0003-0579-0702"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4210110594","display_name":"MRC Weatherall Institute of Molecular Medicine","ror":"https://ror.org/01q496a73","country_code":"GB","type":"facility","lineage":["https://openalex.org/I40120149","https://openalex.org/I4210087105","https://openalex.org/I4210110594","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I4210124851","display_name":"MRC Human Immunology Unit","ror":"https://ror.org/02kcpr174","country_code":"GB","type":"facility","lineage":["https://openalex.org/I40120149","https://openalex.org/I4210087105","https://openalex.org/I4210110594","https://openalex.org/I4210124851","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I90344618","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Antony P. Black","raw_affiliation_strings":["Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom; and","institution_ids":["https://openalex.org/I40120149","https://openalex.org/I4210110594","https://openalex.org/I4210124851","https://openalex.org/I90344618"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070010355","display_name":"Elizabeth A. L. Bateman","orcid":"https://orcid.org/0000-0001-7993-2991","observed_orcids":["https://orcid.org/0000-0001-7993-2991"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4210110594","display_name":"MRC Weatherall Institute of Molecular Medicine","ror":"https://ror.org/01q496a73","country_code":"GB","type":"facility","lineage":["https://openalex.org/I40120149","https://openalex.org/I4210087105","https://openalex.org/I4210110594","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I4210124851","display_name":"MRC Human Immunology Unit","ror":"https://ror.org/02kcpr174","country_code":"GB","type":"facility","lineage":["https://openalex.org/I40120149","https://openalex.org/I4210087105","https://openalex.org/I4210110594","https://openalex.org/I4210124851","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I90344618","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Elizabeth A. Bateman","raw_affiliation_strings":["Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom; and","institution_ids":["https://openalex.org/I40120149","https://openalex.org/I4210110594","https://openalex.org/I4210124851","https://openalex.org/I90344618"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050511886","display_name":"Graham Stuart Ogg","orcid":"https://orcid.org/0000-0002-3097-045X","observed_orcids":["https://orcid.org/0000-0002-3097-045X","https://orcid.org/0000-0002-3702-0107"]},"institutions":[{"id":"https://openalex.org/I2801179840","display_name":"Churchill Hospital","ror":"https://ror.org/009vheq40","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801179840","https://openalex.org/I4210147381"]},{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4210110594","display_name":"MRC Weatherall Institute of Molecular Medicine","ror":"https://ror.org/01q496a73","country_code":"GB","type":"facility","lineage":["https://openalex.org/I40120149","https://openalex.org/I4210087105","https://openalex.org/I4210110594","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I4210124851","display_name":"MRC Human Immunology Unit","ror":"https://ror.org/02kcpr174","country_code":"GB","type":"facility","lineage":["https://openalex.org/I40120149","https://openalex.org/I4210087105","https://openalex.org/I4210110594","https://openalex.org/I4210124851","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I90344618","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Graham S. Ogg","raw_affiliation_strings":["Department of Dermatology, Churchill Hospital, Old Road, Oxford OX3 7LJ, United Kingdom","Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Churchill Hospital, Old Road, Oxford OX3 7LJ, United Kingdom","institution_ids":["https://openalex.org/I2801179840"]},{"raw_affiliation_string":"Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom; and","institution_ids":["https://openalex.org/I40120149","https://openalex.org/I4210110594","https://openalex.org/I4210124851","https://openalex.org/I90344618"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":9.5588,"has_fulltext":false,"cited_by_count":72,"citation_normalized_percentile":{"value":0.9856085,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"104","issue":"13","first_page":"5557","last_page":"5562"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10837","display_name":"Dermatology and Skin Diseases","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10837","display_name":"Dermatology and Skin Diseases","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.004100000020116568,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/staphylococcal-superantigens","display_name":"staphylococcal superantigens","score":0.8960000276565552},{"id":"https://openalex.org/keywords/staphylococcal-enterotoxin-b","display_name":"staphylococcal enterotoxin B","score":0.9860000014305115},{"id":"https://openalex.org/keywords/atopic-dermatitis","display_name":"atopic dermatitis","score":0.9160000085830688},{"id":"https://openalex.org/keywords/der-p-1","display_name":"Der p 1","score":0.7490000128746033},{"id":"https://openalex.org/keywords/allergen-specific-t-cell-responses","display_name":"allergen-specific T cell responses","score":0.8360000252723694},{"id":"https://openalex.org/keywords/th2-cells","display_name":"Th2 cells","score":0.8830000162124634},{"id":"https://openalex.org/keywords/keratinocytes","display_name":"keratinocytes","score":0.5830000042915344},{"id":"https://openalex.org/keywords/il-4","display_name":"IL-4","score":0.7210000157356262},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.9810000061988831},{"id":"https://openalex.org/keywords/icam-1","display_name":"ICAM-1","score":0.9160000085830688},{"id":"https://openalex.org/keywords/cd4-t-cells","display_name":"CD4+ T cells","score":0.7269999980926514},{"id":"https://openalex.org/keywords/staphylococcal-infections","display_name":"staphylococcal infections","score":0.7639999985694885},{"id":"https://openalex.org/keywords/environmental-allergens","display_name":"environmental allergens","score":0.6639999747276306}],"concepts":[{"id":"https://openalex.org/C36333154","wikidata":"https://www.wikidata.org/wiki/Q772950","display_name":"Superantigen","level":4,"score":0.8634679317474365},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.7300316691398621},{"id":"https://openalex.org/C66999527","wikidata":"https://www.wikidata.org/wiki/Q421978","display_name":"Enterotoxin","level":4,"score":0.5426372289657593},{"id":"https://openalex.org/C2780510475","wikidata":"https://www.wikidata.org/wiki/Q186752","display_name":"Allergen","level":3,"score":0.5235342979431152},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5191518664360046},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.4863153398036957},{"id":"https://openalex.org/C195616568","wikidata":"https://www.wikidata.org/wiki/Q128711","display_name":"Epitope","level":3,"score":0.46280142664909363},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.38045477867126465},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.3663327097892761},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.3606381416320801},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.3376617431640625},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.08158934116363525},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07608872652053833},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000485","descriptor_name":"Allergens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000938","descriptor_name":"Antigen-Presenting Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000942","descriptor_name":"Antigens, Bacterial","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000942","descriptor_name":"Antigens, Bacterial","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D003876","descriptor_name":"Dermatitis, Atopic","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007963","descriptor_name":"Leukocytes, Mononuclear","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D007963","descriptor_name":"Leukocytes, Mononuclear","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D008213","descriptor_name":"Lymphocyte Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015496","descriptor_name":"CD4-Positive T-Lymphocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015603","descriptor_name":"Keratinocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D015603","descriptor_name":"Keratinocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015847","descriptor_name":"Interleukin-4","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018418","descriptor_name":"Th2 Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D018418","descriptor_name":"Th2 Cells","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D018925","descriptor_name":"Chemokines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1073/pnas.0700733104","doi":"https://doi.org/10.1073/pnas.0700733104","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.0700733104","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmid:17372219","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17372219","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1838460","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1838460/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},{"id":"pmh:oai:eprints.soton.ac.uk:47939","doi":null,"is_oa":false,"landing_page_url":"https://eprints.soton.ac.uk/47939/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401019","display_name":"ePrints Soton (University of Southampton)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I43439940","host_organization_name":"University of Southampton","host_organization_lineage":["https://openalex.org/I43439940"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:1838460","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1838460/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W1514162038","https://openalex.org/W1527957830","https://openalex.org/W1598450209","https://openalex.org/W1942299758","https://openalex.org/W1966321620","https://openalex.org/W1966622565","https://openalex.org/W1967010539","https://openalex.org/W1968813912","https://openalex.org/W1969090446","https://openalex.org/W1977949287","https://openalex.org/W1982906465","https://openalex.org/W1994589395","https://openalex.org/W1995106901","https://openalex.org/W1995466872","https://openalex.org/W1996672275","https://openalex.org/W2025067737","https://openalex.org/W2025236000","https://openalex.org/W2025961918","https://openalex.org/W2030725214","https://openalex.org/W2039887009","https://openalex.org/W2051008458","https://openalex.org/W2052086128","https://openalex.org/W2055233376","https://openalex.org/W2056453328","https://openalex.org/W2059779473","https://openalex.org/W2060663996","https://openalex.org/W2061742298","https://openalex.org/W2065294752","https://openalex.org/W2068176013","https://openalex.org/W2071743575","https://openalex.org/W2079136206","https://openalex.org/W2090588413","https://openalex.org/W2093512395","https://openalex.org/W2094036101","https://openalex.org/W2105273832","https://openalex.org/W2111665940","https://openalex.org/W2113765099","https://openalex.org/W2117003890","https://openalex.org/W2120012263","https://openalex.org/W2121580723","https://openalex.org/W2129170129","https://openalex.org/W2137865846","https://openalex.org/W2138773604","https://openalex.org/W2139235644","https://openalex.org/W2142209373","https://openalex.org/W2143464311","https://openalex.org/W2161301449","https://openalex.org/W2168668552","https://openalex.org/W4213085061"],"related_works":["https://openalex.org/W1972919078","https://openalex.org/W2056071777","https://openalex.org/W2051194064","https://openalex.org/W2169018022","https://openalex.org/W2612569520","https://openalex.org/W2034841758","https://openalex.org/W1598450209","https://openalex.org/W2607432772","https://openalex.org/W2609922694","https://openalex.org/W1712893432"],"abstract_inverted_index":{"Although":[0],"clinical":[1],"and":[2,11,51,109,117,156,162],"laboratory":[3],"evidence":[4],"support":[5],"roles":[6],"for":[7,159],"both":[8],"staphylococcal":[9,35,82,136],"infection":[10,137],"environmental":[12],"allergens":[13],"in":[14,142],"the":[15,32,38,72,87,143,146,160],"pathogenesis":[16],"of":[17,128,135,145,164],"atopic":[18,165],"dermatitis,":[19],"human":[20],"studies":[21],"have":[22],"largely":[23],"considered":[24],"these":[25],"variables":[26],"independently.":[27],"We":[28,43,79,131],"sought":[29],"to":[30,61,70],"test":[31],"hypothesis":[33],"that":[34,63,81,133],"superantigen":[36],"influences":[37],"allergen-specific":[39,123,147],"T":[40,66,92,125,148],"cell":[41,58,93,126,149],"response.":[42,94],"first":[44],"mapped":[45],"a":[46,139],"Der":[47,89],"p":[48,90],"1":[49],"epitope":[50],"used":[52],"HLA":[53,76],"DRB1*1501":[54],"class":[55,107],"II":[56,108],"tetramer-based":[57],"sorted":[59],"populations":[60],"show":[62],"specific":[64],"CD4(+)":[65,124],"cells":[67],"were":[68],"able":[69],"recognize":[71],"peptide":[73],"presented":[74],"by":[75,99,114],"DR-matched":[77],"keratinocytes.":[78],"observed":[80],"enterotoxin":[83],"B":[84],"(SEB)":[85],"enhanced":[86],"IL-4":[88,120],"1-specific":[91],"This":[95],"response":[96],"was":[97],"mediated":[98],"two":[100,152],"synergistic":[101],"mechanisms:":[102],"first,":[103],"SEB-induced":[104,119],"IFN-gamma":[105],"promoted":[106],"intercellular":[110],"adhesion":[111],"molecule-1":[112],"expression":[113],"presenting":[115],"keratinocytes;":[116],"second,":[118],"directly":[121],"amplified":[122],"production":[127],"many":[129],"cytokines.":[130],"propose":[132],"handling":[134],"is":[138],"critical":[140],"step":[141],"amplification":[144],"response,":[150],"linking":[151],"common":[153],"disease":[154],"associations":[155],"with":[157],"implications":[158],"prevention":[161],"treatment":[163],"disease.":[166]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}
