{"id":"https://openalex.org/W2053059622","doi":"https://doi.org/10.1016/j.eplepsyres.2009.10.012","title":"Hippocampal damage after intra-amygdala kainic acid-induced status epilepticus and seizure preconditioning-mediated neuroprotection in SJL mice","display_name":"Hippocampal damage after intra-amygdala kainic acid-induced status epilepticus and seizure preconditioning-mediated neuroprotection in SJL mice","publication_year":2009,"publication_date":"2009-11-20","ids":{"openalex":"https://openalex.org/W2053059622","doi":"https://doi.org/10.1016/j.eplepsyres.2009.10.012","mag":"2053059622","pmid":"https://pubmed.ncbi.nlm.nih.gov/19931419"},"language":"en","primary_location":{"id":"doi:10.1016/j.eplepsyres.2009.10.012","doi":"https://doi.org/10.1016/j.eplepsyres.2009.10.012","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.eplepsyres.2009.10.012","pdf_url":null,"source":{"id":"https://openalex.org/S144140688","display_name":"Epilepsy Research","issn_l":"0920-1211","issn":["0920-1211","1872-6844"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epilepsy Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://mie-u.repo.nii.ac.jp/record/7626/files/30D16064.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032860273","display_name":"Katsuhiro Tanaka","orcid":"https://orcid.org/0000-0001-5363-1875","observed_orcids":["https://orcid.org/0000-0001-5363-1875"]},"institutions":[{"id":"https://openalex.org/I142762351","display_name":"Royal College of Surgeons in Ireland","ror":"https://ror.org/01hxy9878","country_code":"IE","type":"education","lineage":["https://openalex.org/I142762351"]},{"id":"https://openalex.org/I178574317","display_name":"Mie University","ror":"https://ror.org/01529vy56","country_code":"JP","type":"education","lineage":["https://openalex.org/I178574317"]}],"countries":["IE","JP"],"is_corresponding":false,"raw_author_name":"Katsuhiro Tanaka","raw_affiliation_strings":["Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin 2, Ireland","Department of Neurosurgery, Mie University School of Medicine, Tsu, Mie, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin 2, Ireland","institution_ids":["https://openalex.org/I142762351"]},{"raw_affiliation_string":"Department of Neurosurgery, Mie University School of Medicine, Tsu, Mie, Japan","institution_ids":["https://openalex.org/I178574317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043113948","display_name":"Eva Maria Jimenez-Mateos","orcid":"https://orcid.org/0000-0001-6417-6580","observed_orcids":["https://orcid.org/0000-0001-6417-6580"]},"institutions":[{"id":"https://openalex.org/I142762351","display_name":"Royal College of Surgeons in Ireland","ror":"https://ror.org/01hxy9878","country_code":"IE","type":"education","lineage":["https://openalex.org/I142762351"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Eva M. Jimenez-Mateos","raw_affiliation_strings":["Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin 2, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin 2, Ireland","institution_ids":["https://openalex.org/I142762351"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049041331","display_name":"Satoshi Matsushima","orcid":"https://orcid.org/0000-0002-9940-5205","observed_orcids":["https://orcid.org/0000-0002-9940-5205"]},"institutions":[{"id":"https://openalex.org/I178574317","display_name":"Mie University","ror":"https://ror.org/01529vy56","country_code":"JP","type":"education","lineage":["https://openalex.org/I178574317"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Satoshi Matsushima","raw_affiliation_strings":["Department of Neurosurgery, Mie University School of Medicine, Tsu, Mie, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Mie University School of Medicine, Tsu, Mie, Japan","institution_ids":["https://openalex.org/I178574317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011179401","display_name":"Waro Taki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I178574317","display_name":"Mie University","ror":"https://ror.org/01529vy56","country_code":"JP","type":"education","lineage":["https://openalex.org/I178574317"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Waro Taki","raw_affiliation_strings":["Department of Neurosurgery, Mie University School of Medicine, Tsu, Mie, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Mie University School of Medicine, Tsu, Mie, Japan","institution_ids":["https://openalex.org/I178574317"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002978004","display_name":"David Clifford Henshall","orcid":"https://orcid.org/0000-0001-6237-9632","observed_orcids":["https://orcid.org/0000-0001-6237-9632"]},"institutions":[{"id":"https://openalex.org/I142762351","display_name":"Royal College of Surgeons in Ireland","ror":"https://ror.org/01hxy9878","country_code":"IE","type":"education","lineage":["https://openalex.org/I142762351"]}],"countries":["IE"],"is_corresponding":true,"raw_author_name":"David C. Henshall","raw_affiliation_strings":["Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin 2, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin 2, Ireland","institution_ids":["https://openalex.org/I142762351"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5002978004"],"corresponding_institution_ids":["https://openalex.org/I142762351"],"apc_list":{"value":2880,"currency":"USD","value_usd":2880},"apc_paid":null,"fwci":1.375,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.80048972,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"88","issue":"2-3","first_page":"151","last_page":"161"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/status-epilepticus","display_name":"status epilepticus","score":0.9769999980926514},{"id":"https://openalex.org/keywords/kainic-acid","display_name":"kainic acid","score":0.8299999833106995},{"id":"https://openalex.org/keywords/hippocampal-lesions","display_name":"hippocampal lesions","score":0.8759999871253967},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.9409999847412109},{"id":"https://openalex.org/keywords/sjl-mice","display_name":"SJL mice","score":0.8999999761581421},{"id":"https://openalex.org/keywords/hippocampal-sclerosis","display_name":"hippocampal sclerosis","score":0.8679999709129333},{"id":"https://openalex.org/keywords/ca3","display_name":"CA3","score":0.7960000038146973},{"id":"https://openalex.org/keywords/hilus","display_name":"hilus","score":0.6779999732971191},{"id":"https://openalex.org/keywords/seizure-susceptibility","display_name":"seizure susceptibility","score":0.5820000171661377},{"id":"https://openalex.org/keywords/mouse-strain-differences","display_name":"mouse strain differences","score":0.796999990940094}],"concepts":[{"id":"https://openalex.org/C2776108384","wikidata":"https://www.wikidata.org/wiki/Q390239","display_name":"Kainic acid","level":4,"score":0.9465304613113403},{"id":"https://openalex.org/C2777341932","wikidata":"https://www.wikidata.org/wiki/Q980709","display_name":"Status epilepticus","level":3,"score":0.9222568869590759},{"id":"https://openalex.org/C25498285","wikidata":"https://www.wikidata.org/wiki/Q1981368","display_name":"Neuroprotection","level":2,"score":0.8330515623092651},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.7622588872909546},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.6791780591011047},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6372585296630859},{"id":"https://openalex.org/C2779144063","wikidata":"https://www.wikidata.org/wiki/Q338924","display_name":"Amygdala","level":2,"score":0.5860995650291443},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.46132463216781616},{"id":"https://openalex.org/C2778460930","wikidata":"https://www.wikidata.org/wiki/Q7447053","display_name":"Seizure threshold","level":4,"score":0.4346194863319397},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.39001381397247314},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3753200173377991},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.35635459423065186},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.33504611253738403},{"id":"https://openalex.org/C2775858608","wikidata":"https://www.wikidata.org/wiki/Q576618","display_name":"Anticonvulsant","level":3,"score":0.2844424247741699},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.14175644516944885},{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.12932226061820984},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.056880801916122437}],"mesh":[{"descriptor_ui":"D000679","descriptor_name":"Amygdala","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000679","descriptor_name":"Amygdala","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004567","descriptor_name":"Electrodes, Implanted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D007608","descriptor_name":"Kainic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008845","descriptor_name":"Microinjections","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012598","descriptor_name":"Sclerosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D013226","descriptor_name":"Status Epilepticus","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D013226","descriptor_name":"Status Epilepticus","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D013226","descriptor_name":"Status Epilepticus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D016923","descriptor_name":"Cell Death","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018696","descriptor_name":"Neuroprotective Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019610","descriptor_name":"Cytoprotection","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.eplepsyres.2009.10.012","doi":"https://doi.org/10.1016/j.eplepsyres.2009.10.012","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.eplepsyres.2009.10.012","pdf_url":null,"source":{"id":"https://openalex.org/S144140688","display_name":"Epilepsy Research","issn_l":"0920-1211","issn":["0920-1211","1872-6844"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epilepsy Research","raw_type":"journal-article"},{"id":"pmid:19931419","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19931419","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epilepsy research","raw_type":"Journal Article"},{"id":"pmh:oai:irdb.nii.ac.jp:01189:0002124748","doi":null,"is_oa":true,"landing_page_url":"https://mie-u.repo.nii.ac.jp/records/7626","pdf_url":"https://mie-u.repo.nii.ac.jp/record/7626/files/30D16064.pdf","source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"other"},{"id":"mag:2294708525","doi":null,"is_oa":false,"landing_page_url":"http://ci.nii.ac.jp/naid/500000541407?l=ja","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:irdb.nii.ac.jp:01189:0002124748","doi":null,"is_oa":true,"landing_page_url":"https://mie-u.repo.nii.ac.jp/records/7626","pdf_url":"https://mie-u.repo.nii.ac.jp/record/7626/files/30D16064.pdf","source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"other"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2053059622.pdf","grobid_xml":"https://content.openalex.org/works/W2053059622.grobid-xml"},"referenced_works_count":59,"referenced_works":["https://openalex.org/W1479729971","https://openalex.org/W1479790262","https://openalex.org/W1522048223","https://openalex.org/W1606721682","https://openalex.org/W1965081907","https://openalex.org/W1968474256","https://openalex.org/W1973661730","https://openalex.org/W1978956024","https://openalex.org/W1990365556","https://openalex.org/W1993841014","https://openalex.org/W2000523742","https://openalex.org/W2002915599","https://openalex.org/W2002979809","https://openalex.org/W2004612612","https://openalex.org/W2005027470","https://openalex.org/W2006739799","https://openalex.org/W2007509956","https://openalex.org/W2009223973","https://openalex.org/W2009351843","https://openalex.org/W2009812062","https://openalex.org/W2017083014","https://openalex.org/W2020054158","https://openalex.org/W2023828382","https://openalex.org/W2031616221","https://openalex.org/W2037877714","https://openalex.org/W2038089698","https://openalex.org/W2038707186","https://openalex.org/W2041969644","https://openalex.org/W2047324209","https://openalex.org/W2047962992","https://openalex.org/W2048698596","https://openalex.org/W2049521887","https://openalex.org/W2050542405","https://openalex.org/W2050710535","https://openalex.org/W2052072017","https://openalex.org/W2063175209","https://openalex.org/W2067739666","https://openalex.org/W2070932938","https://openalex.org/W2073160869","https://openalex.org/W2077267486","https://openalex.org/W2079073564","https://openalex.org/W2081115605","https://openalex.org/W2081781030","https://openalex.org/W2083644948","https://openalex.org/W2083837795","https://openalex.org/W2091827844","https://openalex.org/W2099816146","https://openalex.org/W2103839002","https://openalex.org/W2106579385","https://openalex.org/W2115314977","https://openalex.org/W2119124441","https://openalex.org/W2121284276","https://openalex.org/W2123147219","https://openalex.org/W2143532600","https://openalex.org/W2162688668","https://openalex.org/W2166711840","https://openalex.org/W2410772780","https://openalex.org/W2488179669","https://openalex.org/W4211016665"],"related_works":["https://openalex.org/W2047324209","https://openalex.org/W2144491430","https://openalex.org/W2005027470","https://openalex.org/W2038089698","https://openalex.org/W2007734772","https://openalex.org/W2050710535","https://openalex.org/W200373286","https://openalex.org/W2007509956","https://openalex.org/W2088017716","https://openalex.org/W2053130025"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
