{"id":"https://openalex.org/W2052996767","doi":"https://doi.org/10.1590/s1806-37132013000100008","title":"Altera\u00e7\u00f5es espirom\u00e9tricas em doen\u00e7as obstrutivas: afinal, o quanto \u00e9 relevante?","display_name":"Altera\u00e7\u00f5es espirom\u00e9tricas em doen\u00e7as obstrutivas: afinal, o quanto \u00e9 relevante?","publication_year":2013,"publication_date":"2013-02-01","ids":{"openalex":"https://openalex.org/W2052996767","doi":"https://doi.org/10.1590/s1806-37132013000100008","mag":"2052996767","pmid":"https://pubmed.ncbi.nlm.nih.gov/23503486","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4075810"},"language":"pt","primary_location":{"id":"doi:10.1590/s1806-37132013000100008","doi":"https://doi.org/10.1590/s1806-37132013000100008","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s1806-37132013000100008","pdf_url":"https://www.scielo.br/j/jbpneu/a/CJSTvzyqKj86f5wpqFLX6Fj/?lang=pt&format=pdf","source":{"id":"https://openalex.org/S143346047","display_name":"Jornal Brasileiro de Pneumologia","issn_l":"1806-3713","issn":["1806-3713","1806-3756"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","norway-1","oarl","poland-40","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310312248","host_organization_name":"Sociedade Brasileira de Pneumologia e Tisiologia","host_organization_lineage":["https://openalex.org/P4310312248"],"host_organization_lineage_names":["Sociedade Brasileira de Pneumologia e Tisiologia"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Jornal Brasileiro de Pneumologia","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.scielo.br/j/jbpneu/a/CJSTvzyqKj86f5wpqFLX6Fj/?lang=pt&format=pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005809236","display_name":"Andr\u00e9 Luis Pinto Soares","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I35046152","display_name":"Universidade Federal do Rio Grande do Norte","ror":"https://ror.org/04wn09761","country_code":"BR","type":"education","lineage":["https://openalex.org/I35046152"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Andr\u00e9 Luis Pinto Soares","raw_affiliation_strings":["Universidade Federal do Rio Grande do Norte, Brasil","Universidade Federal do Rio Grande do Norte, Natal, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal do Rio Grande do Norte, Brasil","institution_ids":["https://openalex.org/I35046152"]},{"raw_affiliation_string":"Universidade Federal do Rio Grande do Norte, Natal, Brasil","institution_ids":["https://openalex.org/I35046152"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019827152","display_name":"Carlos Alberto de Castro Pereira","orcid":"https://orcid.org/0000-0002-0352-9589","observed_orcids":["https://orcid.org/0000-0002-0352-9589"]},"institutions":[{"id":"https://openalex.org/I88273585","display_name":"Universidade Federal de S\u00e3o Paulo","ror":"https://ror.org/02k5swt12","country_code":"BR","type":"education","lineage":["https://openalex.org/I88273585"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Carlos Alberto de Castro Pereira","raw_affiliation_strings":["Universidade Federal de S\u00e3o Paulo, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal de S\u00e3o Paulo, Brasil","institution_ids":["https://openalex.org/I88273585"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058040740","display_name":"S\u00edlvia Carla Sousa Rodrigues","orcid":"https://orcid.org/0000-0002-4909-9617","observed_orcids":["https://orcid.org/0000-0002-4909-9617"]},"institutions":[{"id":"https://openalex.org/I4210149451","display_name":"Hospital do Servidor P\u00fablico Estadual","ror":"https://ror.org/04r1rhv60","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210149451","https://openalex.org/I4401200253"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Silvia Carla Rodrigues","raw_affiliation_strings":["Hospital do Servidor P\u00fablico Estadual de S\u00e3o Paulo, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital do Servidor P\u00fablico Estadual de S\u00e3o Paulo, Brasil","institution_ids":["https://openalex.org/I4210149451"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2375,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.62211811,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"39","issue":"1","first_page":"56","last_page":"62"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11651","display_name":"Inhalation and Respiratory Drug Delivery","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/spirometry","display_name":"spirometry","score":0.7900000214576721},{"id":"https://openalex.org/keywords/airflow-obstruction","display_name":"airflow obstruction","score":0.9160000085830688},{"id":"https://openalex.org/keywords/placebo-response","display_name":"placebo response","score":0.4819999933242798},{"id":"https://openalex.org/keywords/fev1","display_name":"FEV1","score":0.9039999842643738},{"id":"https://openalex.org/keywords/forced-vital-capacity","display_name":"forced vital capacity","score":0.7570000290870667},{"id":"https://openalex.org/keywords/slow-vital-capacity","display_name":"slow vital capacity","score":0.9959999918937683},{"id":"https://openalex.org/keywords/inspiratory-capacity","display_name":"inspiratory capacity","score":0.9990000128746033},{"id":"https://openalex.org/keywords/dynamic-hyperinflation","display_name":"dynamic hyperinflation","score":0.9110000133514404}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6739135980606079},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4505898058414459},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.42044320702552795},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3416560888290405},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.32207897305488586},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1464938521385193},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001993","descriptor_name":"Bronchodilator Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D001993","descriptor_name":"Bronchodilator Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005163","descriptor_name":"Factor Analysis, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005541","descriptor_name":"Forced Expiratory Volume","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007320","descriptor_name":"Inspiratory Capacity","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008173","descriptor_name":"Lung Diseases, Obstructive","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008173","descriptor_name":"Lung Diseases, Obstructive","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010919","descriptor_name":"Placebos","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D010919","descriptor_name":"Placebos","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D013147","descriptor_name":"Spirometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014797","descriptor_name":"Vital Capacity","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D018709","descriptor_name":"Statistics, Nonparametric","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059085","descriptor_name":"Nasal Sprays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":10,"locations":[{"id":"doi:10.1590/s1806-37132013000100008","doi":"https://doi.org/10.1590/s1806-37132013000100008","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s1806-37132013000100008","pdf_url":"https://www.scielo.br/j/jbpneu/a/CJSTvzyqKj86f5wpqFLX6Fj/?lang=pt&format=pdf","source":{"id":"https://openalex.org/S143346047","display_name":"Jornal Brasileiro de Pneumologia","issn_l":"1806-3713","issn":["1806-3713","1806-3756"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","norway-1","oarl","poland-40","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310312248","host_organization_name":"Sociedade Brasileira de Pneumologia e Tisiologia","host_organization_lineage":["https://openalex.org/P4310312248"],"host_organization_lineage_names":["Sociedade Brasileira de Pneumologia e Tisiologia"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Jornal Brasileiro de Pneumologia","raw_type":"journal-article"},{"id":"pmid:23503486","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23503486","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4075810","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4075810/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Bras Pneumol","raw_type":"Text"},{"id":"pmh:oai:scielo:S1806-37132013000100008","doi":null,"is_oa":true,"landing_page_url":"http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132013000100008","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Jornal Brasileiro de Pneumologia v.39 n.1 2013","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:americanae.aecid.es:2458660","doi":null,"is_oa":true,"landing_page_url":"http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-37132013000100008","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Jornal Brasileiro de Pneumologia v.39 n.1 2013","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:americanae.aecid.es:2788502","doi":null,"is_oa":true,"landing_page_url":"http://americanae.aecid.es/americanae/es/registros/registro.do?tipoRegistro=MTD&idBib=2788502","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"reponame:Reposit\u00f3rio Institucional da UNIFESP","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:doaj.org/article:5ee198359c0442fb900b4760ec2a92a5","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/5ee198359c0442fb900b4760ec2a92a5","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Jornal Brasileiro de Pneumologia, Vol 39, Iss 1, Pp 56-62 (2013)","raw_type":"article"},{"id":"pmh:oai:doaj.org/article:a09f0be9f41c47949e84debaecf38c1b","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/a09f0be9f41c47949e84debaecf38c1b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Jornal Brasileiro de Pneumologia, Vol 39, Iss 1, Pp 56-62 (2013)","raw_type":"article"},{"id":"pmh:oai:repositorio.unifesp.br:11600/7626","doi":null,"is_oa":true,"landing_page_url":"http://repositorio.unifesp.br/handle/11600/7626","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"instacron:UNIFESP","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:2188594706","doi":null,"is_oa":false,"landing_page_url":"http://www.jornaldepneumologia.com.br/audiencia_pdf.asp?aid2=1798&nomeArquivo=2013_39_1_8_english.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1590/s1806-37132013000100008","doi":"https://doi.org/10.1590/s1806-37132013000100008","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s1806-37132013000100008","pdf_url":"https://www.scielo.br/j/jbpneu/a/CJSTvzyqKj86f5wpqFLX6Fj/?lang=pt&format=pdf","source":{"id":"https://openalex.org/S143346047","display_name":"Jornal Brasileiro de Pneumologia","issn_l":"1806-3713","issn":["1806-3713","1806-3756"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","norway-1","oarl","poland-40","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310312248","host_organization_name":"Sociedade Brasileira de Pneumologia e Tisiologia","host_organization_lineage":["https://openalex.org/P4310312248"],"host_organization_lineage_names":["Sociedade Brasileira de Pneumologia e Tisiologia"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Jornal Brasileiro de Pneumologia","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2052996767.pdf","grobid_xml":"https://content.openalex.org/works/W2052996767.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W1416625007","https://openalex.org/W1556777310","https://openalex.org/W1745336096","https://openalex.org/W1750845971","https://openalex.org/W1965418166","https://openalex.org/W1967313011","https://openalex.org/W1968528172","https://openalex.org/W1975696396","https://openalex.org/W1988567254","https://openalex.org/W2000430593","https://openalex.org/W2002082935","https://openalex.org/W2007810665","https://openalex.org/W2015260858","https://openalex.org/W2038092262","https://openalex.org/W2069639431","https://openalex.org/W2093104038","https://openalex.org/W2097125229","https://openalex.org/W2108401555","https://openalex.org/W2112278267","https://openalex.org/W2124879124","https://openalex.org/W2125078269","https://openalex.org/W2129923139","https://openalex.org/W2134462801","https://openalex.org/W2143454168","https://openalex.org/W2149766225","https://openalex.org/W2150508175","https://openalex.org/W2150614396","https://openalex.org/W2159728269","https://openalex.org/W2169980433","https://openalex.org/W2604596332","https://openalex.org/W2614123514"],"related_works":["https://openalex.org/W2188594706","https://openalex.org/W2611317135","https://openalex.org/W59373898","https://openalex.org/W2552288431","https://openalex.org/W4252391197","https://openalex.org/W4416636565","https://openalex.org/W1981381142","https://openalex.org/W1535873138","https://openalex.org/W1995824755","https://openalex.org/W2038092262"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"establish":[2],"the":[3,46,50,60,110,119,124,223,242,255],"upper":[4,125],"limits":[5,126],"for":[6,127,262],"changes":[7,66,106,248,276],"in":[8,22,45,67,100,277],"FEV1,":[9,68],"slow":[10],"vital":[11],"capacity":[12,17],"(SVC),":[13],"FVC,":[14,70,231],"and":[15,30,54,58,71,84,91,113,116,146,164,176,186,209,218,237,252,264,280],"inspiratory":[16],"(IC)":[18],"after":[19,59,117],"placebo":[20,63],"administration":[21,61],"patients":[23,198],"with":[24,33,199],"airflow":[25,34,200],"obstruction.":[26],"METHODS:":[27],"One":[28],"hundred":[29],"two":[31],"adults":[32],"obstruction":[35],"(FEV1":[36],"=":[37,135,139,143,148,156,159,162,166,178,181,184,188],"62":[38],"\u00b1":[39],"19%":[40],"of":[41,49,62,79,86,171,193,220,239,254],"predicted)":[42],"were":[43,73,131],"included":[44],"study.":[47],"All":[48],"participants":[51],"performed":[52,99],"SVC":[53,142,161,183],"FVC":[55,138,158,180,208],"maneuvers":[56],"before":[57],"spray.":[64],"The":[65],"SVC,":[69],"IC":[72,147,165,187,202],"expressed":[74],"as":[75,132,152,169,191],"absolute":[76,153],"values,":[77,83,88,120],"percentage":[78,85,170,192],"change":[80,172,221,240],"from":[81,173,222,241],"baseline":[82,174,224,243],"predicted":[87,194,256],"95%":[89,111],"CIs":[90,112],"95th":[92,114],"percentiles":[93,115],"being":[94],"calculated.":[95],"Factor":[96],"analysis":[97],"was":[98],"order":[101],"to":[102],"determine":[103],"how":[104],"those":[105],"clustered.":[107],"RESULTS:":[108],"Considering":[109],"rounding":[118],"we":[121],"found":[122],"that":[123],"a":[128],"significant":[129,261],"response":[130],"follows:":[133],"FEV1":[134,155,177,263],"0.20":[136,140,235,250],"L,":[137,141,145],"0.25":[144],"0.30":[149,216],"L":[150,217,236,251],"(expressed":[151,168,190],"values);":[154,175],"12%,":[157],"7%,":[160,179,185],"10%,":[163],"15%":[167,219],"6%,":[182],"12%":[189],"values).":[195],"CONCLUSIONS:":[196],"In":[197],"obstruction,":[201],"varies":[203],"more":[204],"widely":[205],"than":[206,215,234],"do":[207],"SVC.":[210],"For":[211,230],"IC,":[212],"values":[213,232],"greater":[214,233],"value":[225,244,257],"can":[226,258],"be":[227,259],"considered":[228,260],"significant.":[229,246],"7%":[238,253],"are":[245],"Alternatively,":[247],"exceeding":[249],"FVC.":[265],"On":[266],"factor":[267],"analysis,":[268],"spirometric":[269],"parameters":[270],"clustered":[271],"into":[272],"three":[273],"dimensions,":[274],"expressing":[275],"flows,":[278],"volumes,":[279],"dynamic":[281],"hyperinflation.":[282]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}