{"id":"https://openalex.org/W2052631664","doi":"https://doi.org/10.1038/ni965","title":"Efficient thymic immigration of B220+ lymphoid-restricted bone marrow cells with T precursor potential","display_name":"Efficient thymic immigration of B220+ lymphoid-restricted bone marrow cells with T precursor potential","publication_year":2003,"publication_date":"2003-08-17","ids":{"openalex":"https://openalex.org/W2052631664","doi":"https://doi.org/10.1038/ni965","mag":"2052631664","pmid":"https://pubmed.ncbi.nlm.nih.gov/12925850"},"language":"en","primary_location":{"id":"doi:10.1038/ni965","doi":"https://doi.org/10.1038/ni965","is_oa":false,"landing_page_url":"https://doi.org/10.1038/ni965","pdf_url":null,"source":{"id":"https://openalex.org/S41063453","display_name":"Nature Immunology","issn_l":"1529-2908","issn":["1529-2908","1529-2916"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Immunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036159958","display_name":"Colin H. Martin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210134579","display_name":"Dana-Farber/Harvard Cancer Center","ror":"https://ror.org/03pvyf116","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210134579"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Colin H Martin","raw_affiliation_strings":["Department of Pathology, Harvard Medical School, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Harvard Medical School, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210134579"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084923564","display_name":"Iannis Aifantis","orcid":"https://orcid.org/0000-0001-6857-1035","observed_orcids":["https://orcid.org/0000-0001-6857-1035"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210134579","display_name":"Dana-Farber/Harvard Cancer Center","ror":"https://ror.org/03pvyf116","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210134579"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Iannis Aifantis","raw_affiliation_strings":["Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, 60637, Illinois, USA","Department of Pathology, Harvard Medical School, Dana-Farber Cancer Institute, Boston, 02115, Massachusetts, USA","Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, USA","Department of Pathology, Harvard Medical School, Dana-Farber Cancer Institute, Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, 60637, Illinois, USA","institution_ids":["https://openalex.org/I40347166"]},{"raw_affiliation_string":"Department of Pathology, Harvard Medical School, Dana-Farber Cancer Institute, Boston, 02115, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210134579"]},{"raw_affiliation_string":"Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, USA","institution_ids":["https://openalex.org/I40347166"]},{"raw_affiliation_string":"Department of Pathology, Harvard Medical School, Dana-Farber Cancer Institute, Boston, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210134579"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102760106","display_name":"Mar\u00eda Lucila Scimone","orcid":"https://orcid.org/0000-0002-3226-6888","observed_orcids":["https://orcid.org/0000-0002-3226-6888"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M Lucila Scimone","raw_affiliation_strings":["Department of Pathology, Howard Hughes Medical Institute, Harvard Medical School, Boston, 02115, Massachusetts, USA","Department of Pathology, Howard Hughes Medical Institute, Harvard Medical School, Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Howard Hughes Medical Institute, Harvard Medical School, Boston, 02115, Massachusetts, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Pathology, Howard Hughes Medical Institute, Harvard Medical School, Boston, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042136097","display_name":"Ulrich H. von Andrian","orcid":"https://orcid.org/0000-0003-4231-2283","observed_orcids":["https://orcid.org/0000-0003-4231-2283"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ulrich H von Andrian","raw_affiliation_strings":["Department of Pathology, Howard Hughes Medical Institute, Harvard Medical School, Boston, 02115, Massachusetts, USA","Department of Pathology, Howard Hughes Medical Institute, Harvard Medical School, Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Howard Hughes Medical Institute, Harvard Medical School, Boston, 02115, Massachusetts, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Pathology, Howard Hughes Medical Institute, Harvard Medical School, Boston, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004192129","display_name":"Boris Reizis","orcid":"https://orcid.org/0000-0003-1140-7853","observed_orcids":["https://orcid.org/0000-0003-1140-7853"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Boris Reizis","raw_affiliation_strings":["Department of Genetics and Howard Hughes Medical Institute, Harvard Medical School, Boston, 02115, Massachusetts, USA","Department of Genetics and Howard Hughes Medical Institute, Harvard Medical School,  Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics and Howard Hughes Medical Institute, Harvard Medical School, Boston, 02115, Massachusetts, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Genetics and Howard Hughes Medical Institute, Harvard Medical School,  Boston, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012087369","display_name":"Harald von Boehmer","orcid":"https://orcid.org/0000-0002-9714-1613","observed_orcids":["https://orcid.org/0000-0002-9714-1613"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210134579","display_name":"Dana-Farber/Harvard Cancer Center","ror":"https://ror.org/03pvyf116","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210134579"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Harald von Boehmer","raw_affiliation_strings":["Department of Pathology, Harvard Medical School, Dana-Farber Cancer Institute, Boston, 02115, Massachusetts, USA","Department of Pathology, Harvard Medical School, Dana-Farber Cancer Institute, Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Harvard Medical School, Dana-Farber Cancer Institute, Boston, 02115, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210134579"]},{"raw_affiliation_string":"Department of Pathology, Harvard Medical School, Dana-Farber Cancer Institute, Boston, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210134579"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086035685","display_name":"Fotini Gounari","orcid":"https://orcid.org/0000-0003-2936-066X","observed_orcids":["https://orcid.org/0000-0003-2936-066X"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210134579","display_name":"Dana-Farber/Harvard Cancer Center","ror":"https://ror.org/03pvyf116","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210134579"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fotini Gounari","raw_affiliation_strings":["Department of Pathology, Harvard Medical School, Dana-Farber Cancer Institute, Boston, 02115, Massachusetts, USA","Department of Pathology, Harvard Medical School, Dana-Farber Cancer Institute, Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Harvard Medical School, Dana-Farber Cancer Institute, Boston, 02115, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210134579"]},{"raw_affiliation_string":"Department of Pathology, Harvard Medical School, Dana-Farber Cancer Institute, Boston, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210134579"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5012087369"],"corresponding_institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210134579"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":8.8637,"has_fulltext":false,"cited_by_count":200,"citation_normalized_percentile":{"value":0.98556881,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"4","issue":"9","first_page":"866","last_page":"873"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.899399995803833,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.899399995803833,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.09700000286102295,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thymic-emigration","display_name":"thymic emigration","score":0.7710000276565552},{"id":"https://openalex.org/keywords/common-lymphoid-progenitors","display_name":"common lymphoid progenitors","score":0.7139999866485596},{"id":"https://openalex.org/keywords/c-kit","display_name":"CD117","score":0.6930000185966492},{"id":"https://openalex.org/keywords/thymic-organ-culture","display_name":"thymic organ culture","score":0.7799999713897705},{"id":"https://openalex.org/keywords/bone-marrow-cells","display_name":"bone marrow cells","score":0.5410000085830688},{"id":"https://openalex.org/keywords/t-cell-commitment","display_name":"T cell commitment","score":0.3700000047683716},{"id":"https://openalex.org/keywords/b-cell-lineage","display_name":"B-cell lineage","score":0.546999990940094}],"concepts":[{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.60919588804245},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6046654582023621},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5595575571060181},{"id":"https://openalex.org/C79904392","wikidata":"https://www.wikidata.org/wiki/Q5976738","display_name":"Lymphopoiesis","level":4,"score":0.5537638068199158},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5443141460418701},{"id":"https://openalex.org/C117262875","wikidata":"https://www.wikidata.org/wiki/Q5135057","display_name":"Clonogenic assay","level":3,"score":0.5093942284584045},{"id":"https://openalex.org/C124964019","wikidata":"https://www.wikidata.org/wiki/Q11616062","display_name":"Precursor cell","level":3,"score":0.45759448409080505},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4289681911468506},{"id":"https://openalex.org/C2992511266","wikidata":"https://www.wikidata.org/wiki/Q1093098","display_name":"Gene rearrangement","level":3,"score":0.4211430549621582},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.41857945919036865},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.36771342158317566},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3481824994087219},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.28706642985343933},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.18959996104240417},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.16565650701522827},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15760678052902222},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.14541351795196533},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.07316970825195312},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001854","descriptor_name":"Bone Marrow Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D001854","descriptor_name":"Bone Marrow Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D005434","descriptor_name":"Flow Cytometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008822","descriptor_name":"Mice, Transgenic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D013950","descriptor_name":"Thymus Gland","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D013950","descriptor_name":"Thymus Gland","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015375","descriptor_name":"Receptors, Interleukin-2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015375","descriptor_name":"Receptors, Interleukin-2","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D017493","descriptor_name":"Leukocyte Common Antigens","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017493","descriptor_name":"Leukocyte Common Antigens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018941","descriptor_name":"Antigens, CD19","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018941","descriptor_name":"Antigens, CD19","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D019009","descriptor_name":"Proto-Oncogene Proteins c-kit","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019009","descriptor_name":"Proto-Oncogene Proteins c-kit","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D019070","descriptor_name":"Cell Lineage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020133","descriptor_name":"Reverse Transcriptase Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1038/ni965","doi":"https://doi.org/10.1038/ni965","is_oa":false,"landing_page_url":"https://doi.org/10.1038/ni965","pdf_url":null,"source":{"id":"https://openalex.org/S41063453","display_name":"Nature Immunology","issn_l":"1529-2908","issn":["1529-2908","1529-2916"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Immunology","raw_type":"journal-article"},{"id":"pmid:12925850","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12925850","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature immunology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.75,"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G395873286","display_name":null,"funder_award_id":"R01A145846","funder_id":"https://openalex.org/F4320332505","funder_display_name":"U.S. Public Health Service"},{"id":"https://openalex.org/G4938483033","display_name":null,"funder_award_id":"R01A147281","funder_id":"https://openalex.org/F4320332505","funder_display_name":"U.S. Public Health Service"}],"funders":[{"id":"https://openalex.org/F4320332505","display_name":"U.S. Public Health Service","ror":"https://ror.org/05xf94514"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W201211866","https://openalex.org/W1539943711","https://openalex.org/W1587921637","https://openalex.org/W1642274515","https://openalex.org/W1973035870","https://openalex.org/W1980212327","https://openalex.org/W1996418577","https://openalex.org/W2003371248","https://openalex.org/W2028735719","https://openalex.org/W2036340292","https://openalex.org/W2038078421","https://openalex.org/W2043588936","https://openalex.org/W2044766358","https://openalex.org/W2045294448","https://openalex.org/W2054201079","https://openalex.org/W2058781233","https://openalex.org/W2060513583","https://openalex.org/W2061307900","https://openalex.org/W2067131315","https://openalex.org/W2069501059","https://openalex.org/W2070543343","https://openalex.org/W2070640889","https://openalex.org/W2080801585","https://openalex.org/W2082746204","https://openalex.org/W2093931465","https://openalex.org/W2094505085","https://openalex.org/W2096015304","https://openalex.org/W2100378064","https://openalex.org/W2117455815","https://openalex.org/W2120141012","https://openalex.org/W2144579631","https://openalex.org/W2152414109","https://openalex.org/W2163720296","https://openalex.org/W2172294715","https://openalex.org/W2396697322"],"related_works":["https://openalex.org/W2136287764","https://openalex.org/W2031126129","https://openalex.org/W2080801585","https://openalex.org/W2044677032","https://openalex.org/W1528042729","https://openalex.org/W4238238131","https://openalex.org/W2980112015","https://openalex.org/W7097764970","https://openalex.org/W2038078421","https://openalex.org/W1644228054"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":6}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}