{"id":"https://openalex.org/W2052278186","doi":"https://doi.org/10.1073/pnas.96.24.13762","title":"Sorting by diffusion: An asymmetric obstacle course for continuous molecular separation","display_name":"Sorting by diffusion: An asymmetric obstacle course for continuous molecular separation","publication_year":1999,"publication_date":"1999-11-23","ids":{"openalex":"https://openalex.org/W2052278186","doi":"https://doi.org/10.1073/pnas.96.24.13762","mag":"2052278186","pmid":"https://pubmed.ncbi.nlm.nih.gov/10570146","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/24138"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.96.24.13762","doi":"https://doi.org/10.1073/pnas.96.24.13762","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.96.24.13762","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/24138","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046234546","display_name":"Chia\u2010Fu Chou","orcid":"https://orcid.org/0000-0003-0070-5556","observed_orcids":["https://orcid.org/0000-0003-0070-5556"]},"institutions":[{"id":"https://openalex.org/I20089843","display_name":"Princeton University","ror":"https://ror.org/00hx57361","country_code":"US","type":"education","lineage":["https://openalex.org/I20089843"]},{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Chia-Fu Chou","raw_affiliation_strings":["Departments of Physics and Molecular Biology, Princeton University, Princeton, NJ 08544; School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853; Niels Bohr Institute, Blegdamsvej 17, 2100 Copenhagen, Denmark; and Cavendish Laboratory, Cambridge University, Cambridge, CB3 0HE, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Physics and Molecular Biology, Princeton University, Princeton, NJ 08544; School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853; Niels Bohr Institute, Blegdamsvej 17, 2100 Copenhagen, Denmark; and Cavendish Laboratory, Cambridge University, Cambridge, CB3 0HE, United Kingdom","institution_ids":["https://openalex.org/I20089843","https://openalex.org/I205783295","https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064277207","display_name":"Olgica Bakajin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I20089843","display_name":"Princeton University","ror":"https://ror.org/00hx57361","country_code":"US","type":"education","lineage":["https://openalex.org/I20089843"]},{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Olgica Bakajin","raw_affiliation_strings":["Departments of Physics and Molecular Biology, Princeton University, Princeton, NJ 08544; School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853; Niels Bohr Institute, Blegdamsvej 17, 2100 Copenhagen, Denmark; and Cavendish Laboratory, Cambridge University, Cambridge, CB3 0HE, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Physics and Molecular Biology, Princeton University, Princeton, NJ 08544; School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853; Niels Bohr Institute, Blegdamsvej 17, 2100 Copenhagen, Denmark; and Cavendish Laboratory, Cambridge University, Cambridge, CB3 0HE, United Kingdom","institution_ids":["https://openalex.org/I20089843","https://openalex.org/I205783295","https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068228499","display_name":"Stephen Turner","orcid":"https://orcid.org/0000-0001-9140-9028","observed_orcids":["https://orcid.org/0000-0001-9140-9028"]},"institutions":[{"id":"https://openalex.org/I20089843","display_name":"Princeton University","ror":"https://ror.org/00hx57361","country_code":"US","type":"education","lineage":["https://openalex.org/I20089843"]},{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Stephen W. P. Turner","raw_affiliation_strings":["Departments of Physics and Molecular Biology, Princeton University, Princeton, NJ 08544; School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853; Niels Bohr Institute, Blegdamsvej 17, 2100 Copenhagen, Denmark; and Cavendish Laboratory, Cambridge University, Cambridge, CB3 0HE, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Physics and Molecular Biology, Princeton University, Princeton, NJ 08544; School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853; Niels Bohr Institute, Blegdamsvej 17, 2100 Copenhagen, Denmark; and Cavendish Laboratory, Cambridge University, Cambridge, CB3 0HE, United Kingdom","institution_ids":["https://openalex.org/I20089843","https://openalex.org/I205783295","https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113437276","display_name":"Thomas A. J. Duke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I20089843","display_name":"Princeton University","ror":"https://ror.org/00hx57361","country_code":"US","type":"education","lineage":["https://openalex.org/I20089843"]},{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["DK","GB","US"],"is_corresponding":false,"raw_author_name":"Thomas A. J. Duke","raw_affiliation_strings":["Departments of Physics and Molecular Biology, Princeton University, Princeton, NJ 08544; School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853; Niels Bohr Institute, Blegdamsvej 17, 2100 Copenhagen, Denmark; and Cavendish Laboratory, Cambridge University, Cambridge, CB3 0HE, United Kingdom","University of Copenhagen"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Physics and Molecular Biology, Princeton University, Princeton, NJ 08544; School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853; Niels Bohr Institute, Blegdamsvej 17, 2100 Copenhagen, Denmark; and Cavendish Laboratory, Cambridge University, Cambridge, CB3 0HE, United Kingdom","institution_ids":["https://openalex.org/I20089843","https://openalex.org/I205783295","https://openalex.org/I241749"]},{"raw_affiliation_string":"University of Copenhagen","institution_ids":["https://openalex.org/I124055696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101896605","display_name":"Shirley S. Chan","orcid":"https://orcid.org/0000-0002-6505-6617","observed_orcids":["https://orcid.org/0000-0002-6505-6617"]},"institutions":[{"id":"https://openalex.org/I20089843","display_name":"Princeton University","ror":"https://ror.org/00hx57361","country_code":"US","type":"education","lineage":["https://openalex.org/I20089843"]},{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Shirley S. Chan","raw_affiliation_strings":["Departments of Physics and Molecular Biology, Princeton University, Princeton, NJ 08544; School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853; Niels Bohr Institute, Blegdamsvej 17, 2100 Copenhagen, Denmark; and Cavendish Laboratory, Cambridge University, Cambridge, CB3 0HE, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Physics and Molecular Biology, Princeton University, Princeton, NJ 08544; School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853; Niels Bohr Institute, Blegdamsvej 17, 2100 Copenhagen, Denmark; and Cavendish Laboratory, Cambridge University, Cambridge, CB3 0HE, United Kingdom","institution_ids":["https://openalex.org/I20089843","https://openalex.org/I205783295","https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106732730","display_name":"Edward C. Cox","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I20089843","display_name":"Princeton University","ror":"https://ror.org/00hx57361","country_code":"US","type":"education","lineage":["https://openalex.org/I20089843"]},{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Edward C. Cox","raw_affiliation_strings":["Departments of Physics and Molecular Biology, Princeton University, Princeton, NJ 08544; School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853; Niels Bohr Institute, Blegdamsvej 17, 2100 Copenhagen, Denmark; and Cavendish Laboratory, Cambridge University, Cambridge, CB3 0HE, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Physics and Molecular Biology, Princeton University, Princeton, NJ 08544; School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853; Niels Bohr Institute, Blegdamsvej 17, 2100 Copenhagen, Denmark; and Cavendish Laboratory, Cambridge University, Cambridge, CB3 0HE, United Kingdom","institution_ids":["https://openalex.org/I20089843","https://openalex.org/I205783295","https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029356125","display_name":"Harold G. Craighead","orcid":"https://orcid.org/0000-0002-5675-3955","observed_orcids":["https://orcid.org/0000-0002-5675-3955"]},"institutions":[{"id":"https://openalex.org/I1295876152","display_name":"Houston Methodist","ror":"https://ror.org/027zt9171","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295876152"]},{"id":"https://openalex.org/I20089843","display_name":"Princeton University","ror":"https://ror.org/00hx57361","country_code":"US","type":"education","lineage":["https://openalex.org/I20089843"]},{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Harold G. Craighead","raw_affiliation_strings":["Departments of Physics and Molecular Biology, Princeton University, Princeton, NJ 08544; School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853; Niels Bohr Institute, Blegdamsvej 17, 2100 Copenhagen, Denmark; and Cavendish Laboratory, Cambridge University, Cambridge, CB3 0HE, United Kingdom","Houston Methodist"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Physics and Molecular Biology, Princeton University, Princeton, NJ 08544; School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853; Niels Bohr Institute, Blegdamsvej 17, 2100 Copenhagen, Denmark; and Cavendish Laboratory, Cambridge University, Cambridge, CB3 0HE, United Kingdom","institution_ids":["https://openalex.org/I20089843","https://openalex.org/I205783295","https://openalex.org/I241749"]},{"raw_affiliation_string":"Houston Methodist","institution_ids":["https://openalex.org/I1295876152"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081117311","display_name":"Robert H. Austin","orcid":"https://orcid.org/0000-0002-4269-6793","observed_orcids":["https://orcid.org/0000-0002-4269-6793"]},"institutions":[{"id":"https://openalex.org/I20089843","display_name":"Princeton University","ror":"https://ror.org/00hx57361","country_code":"US","type":"education","lineage":["https://openalex.org/I20089843"]},{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Robert H. Austin","raw_affiliation_strings":["Departments of Physics and Molecular Biology, Princeton University, Princeton, NJ 08544; School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853; Niels Bohr Institute, Blegdamsvej 17, 2100 Copenhagen, Denmark; and Cavendish Laboratory, Cambridge University, Cambridge, CB3 0HE, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Physics and Molecular Biology, Princeton University, Princeton, NJ 08544; School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853; Niels Bohr Institute, Blegdamsvej 17, 2100 Copenhagen, Denmark; and Cavendish Laboratory, Cambridge University, Cambridge, CB3 0HE, United Kingdom","institution_ids":["https://openalex.org/I20089843","https://openalex.org/I205783295","https://openalex.org/I241749"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":7.1372,"has_fulltext":false,"cited_by_count":196,"citation_normalized_percentile":{"value":0.97873362,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"96","issue":"24","first_page":"13762","last_page":"13765"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.9688000082969666,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.9688000082969666,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12850","display_name":"Field-Flow Fractionation Techniques","score":0.013199999928474426,"subfield":{"id":"https://openalex.org/subfields/2206","display_name":"Computational Mechanics"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.0052999998442828655,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-size-separation","display_name":"DNA size separation","score":0.6790000200271606},{"id":"https://openalex.org/keywords/diffusion-coefficient","display_name":"diffusion coefficient","score":0.8130000233650208},{"id":"https://openalex.org/keywords/silicon-microfluidics","display_name":"silicon microfluidics","score":0.40799999237060547},{"id":"https://openalex.org/keywords/molecular-sieving","display_name":"molecular sieving","score":0.3790000081062317}],"concepts":[{"id":"https://openalex.org/C112401455","wikidata":"https://www.wikidata.org/wiki/Q178036","display_name":"Brownian motion","level":2,"score":0.5449276566505432},{"id":"https://openalex.org/C69357855","wikidata":"https://www.wikidata.org/wiki/Q163214","display_name":"Diffusion","level":2,"score":0.536220908164978},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.49363458156585693},{"id":"https://openalex.org/C160671074","wikidata":"https://www.wikidata.org/wiki/Q267131","display_name":"Wafer","level":2,"score":0.484110951423645},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.4400904178619385},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.42330318689346313},{"id":"https://openalex.org/C111696304","wikidata":"https://www.wikidata.org/wiki/Q2303697","display_name":"Sorting","level":2,"score":0.4101574420928955},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.4003008008003235},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.3733379542827606},{"id":"https://openalex.org/C159467904","wikidata":"https://www.wikidata.org/wiki/Q2001702","display_name":"Chemical physics","level":1,"score":0.3625313937664032},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.34811580181121826},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.34569114446640015},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.13646942377090454},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.1093565821647644},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1007034182548523},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.08210122585296631},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.07881796360015869},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004058","descriptor_name":"Diffusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D005591","descriptor_name":"Chemical Fractionation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1073/pnas.96.24.13762","doi":"https://doi.org/10.1073/pnas.96.24.13762","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.96.24.13762","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:24138","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/24138","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},{"id":"pmid:10570146","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10570146","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:128701","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/128701/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"P NATL ACAD SCI USA , 96 (24) 13762 - 13765. (1999)","raw_type":"Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:24138","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/24138","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1114233281","display_name":null,"funder_award_id":"GM55453","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G219241424","display_name":"Micro and Nanofabricated Devices for DNA Analysis","funder_award_id":"R01HG001506","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G49909925","display_name":"ANALYSIS &PURIFICATION OF DNA IN MICROFABRICATED ARRAYS","funder_award_id":"1r01gm055453-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7090561996","display_name":null,"funder_award_id":"HG01506","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"}],"funders":[{"id":"https://openalex.org/F4320320006","display_name":"Royal Society","ror":"https://ror.org/03wnrjx87"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332167","display_name":"Directorate for Biological Sciences","ror":"https://ror.org/001xhss06"},{"id":"https://openalex.org/F4320337348","display_name":"National Human Genome Research Institute","ror":"https://ror.org/00baak391"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W602451748","https://openalex.org/W1970338457","https://openalex.org/W1975673638","https://openalex.org/W1979108322","https://openalex.org/W1996224306","https://openalex.org/W1999726057","https://openalex.org/W2009213717","https://openalex.org/W2043437150","https://openalex.org/W2046597732","https://openalex.org/W2069565989","https://openalex.org/W2117817813","https://openalex.org/W2142950404","https://openalex.org/W2147230970","https://openalex.org/W2148927531","https://openalex.org/W2983363128","https://openalex.org/W3021046817","https://openalex.org/W4254527948","https://openalex.org/W6606577101"],"related_works":["https://openalex.org/W1975673638","https://openalex.org/W3113083663","https://openalex.org/W2038908517","https://openalex.org/W2393548626","https://openalex.org/W2151888924","https://openalex.org/W2599092689","https://openalex.org/W3068086587","https://openalex.org/W117614968","https://openalex.org/W2597048624","https://openalex.org/W2091263419"],"abstract_inverted_index":{"A":[0,53],"separation":[1],"technique":[2],"employing":[3],"a":[4,24,72],"microfabricated":[5],"sieve":[6,21],"has":[7],"been":[8],"demonstrated":[9],"by":[10,57],"observing":[11],"the":[12,33,40,63,94],"motion":[13,35],"of":[14,17,23,27,36,59,79],"DNA":[15,60],"molecules":[16,37,61],"different":[18],"size.":[19],"The":[20,77],"consists":[22],"two-dimensional":[25],"lattice":[26],"obstacles":[28],"whose":[29],"asymmetric":[30],"disposition":[31],"rectifies":[32],"Brownian":[34],"driven":[38],"through":[39],"device,":[41],"causing":[42],"them":[43],"to":[44,93],"follow":[45],"paths":[46],"that":[47,83],"depend":[48],"on":[49],"their":[50],"diffusion":[51],"coefficient.":[52],"nominal":[54],"6%":[55],"resolution":[56],"length":[58],"in":[62,71,91,99],"size":[64],"range":[65],"15-30":[66],"kbp":[67],"may":[68],"be":[69,86],"achieved":[70],"4-inch":[73],"(10-cm)":[74],"silicon":[75],"wafer.":[76],"advantage":[78],"this":[80],"method":[81],"is":[82],"samples":[84],"can":[85],"loaded":[87],"and":[88],"sorted":[89],"continuously,":[90],"contrast":[92],"batch":[95],"mode":[96],"commonly":[97],"used":[98],"gel":[100],"electrophoresis.":[101]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":11},{"year":2012,"cited_by_count":7}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
