{"id":"https://openalex.org/W2052257223","doi":"https://doi.org/10.1097/crd.0000000000000026","title":"Prevention and Treatment In Utero of Autoimmune-Associated Congenital Heart Block","display_name":"Prevention and Treatment In Utero of Autoimmune-Associated Congenital Heart Block","publication_year":2014,"publication_date":"2014-07-22","ids":{"openalex":"https://openalex.org/W2052257223","doi":"https://doi.org/10.1097/crd.0000000000000026","mag":"2052257223","pmid":"https://pubmed.ncbi.nlm.nih.gov/25050975","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4539276"},"language":"en","primary_location":{"id":"doi:10.1097/crd.0000000000000026","doi":"https://doi.org/10.1097/crd.0000000000000026","is_oa":false,"landing_page_url":"https://doi.org/10.1097/crd.0000000000000026","pdf_url":null,"source":{"id":"https://openalex.org/S173369630","display_name":"Cardiology in Review","issn_l":"1061-5377","issn":["1061-5377","1538-4683"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiology in Review","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4539276","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003469260","display_name":"Amit Saxena","orcid":"https://orcid.org/0000-0003-0098-1083","observed_orcids":["https://orcid.org/0000-0003-0098-1083"]},"institutions":[{"id":"https://openalex.org/I181190671","display_name":"New York Medical College","ror":"https://ror.org/03dkvy735","country_code":"US","type":"education","lineage":["https://openalex.org/I181190671"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Amit Saxena","raw_affiliation_strings":["From the *Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York, NY; and \u2020Division of Pediatric Cardiology, Department of Pediatrics, New York Medical College, Valhalla, NY","Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the *Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York, NY; and \u2020Division of Pediatric Cardiology, Department of Pediatrics, New York Medical College, Valhalla, NY","institution_ids":["https://openalex.org/I181190671","https://openalex.org/I57206974"]},{"raw_affiliation_string":"Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York, NY","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063660714","display_name":"Peter Izmirly","orcid":"https://orcid.org/0000-0001-5445-2182","observed_orcids":["https://orcid.org/0000-0001-5445-2182"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Peter M Izmirly","raw_affiliation_strings":["Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York, NY","Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York, NY; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York, NY","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York, NY; and","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072305569","display_name":"Barbara Mendez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Barbara Mendez","raw_affiliation_strings":["Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York, NY","Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York, NY; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York, NY","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York, NY; and","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072473587","display_name":"Jill P. Buyon","orcid":"https://orcid.org/0000-0002-3852-7129","observed_orcids":["https://orcid.org/0000-0002-3852-7129"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jill P. Buyon","raw_affiliation_strings":["Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York, NY","Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York, NY; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York, NY","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York, NY; and","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058495467","display_name":"DEBORAH M. FRIEDMAN","orcid":"https://orcid.org/0000-0002-4757-1201","observed_orcids":["https://orcid.org/0000-0002-4757-1201"]},"institutions":[{"id":"https://openalex.org/I181190671","display_name":"New York Medical College","ror":"https://ror.org/03dkvy735","country_code":"US","type":"education","lineage":["https://openalex.org/I181190671"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Deborah M. Friedman","raw_affiliation_strings":["Division of Pediatric Cardiology, Department of Pediatrics, New York Medical College, Valhalla, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pediatric Cardiology, Department of Pediatrics, New York Medical College, Valhalla, NY","institution_ids":["https://openalex.org/I181190671"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5003469260","https://openalex.org/A5063660714","https://openalex.org/A5072305569","https://openalex.org/A5072473587"],"corresponding_institution_ids":["https://openalex.org/I181190671","https://openalex.org/I57206974"],"apc_list":null,"apc_paid":null,"fwci":1.1923,"has_fulltext":false,"cited_by_count":108,"citation_normalized_percentile":{"value":0.73259821,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"22","issue":"6","first_page":"263","last_page":"267"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12230","display_name":"Cardiovascular Issues in Pregnancy","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/congenital-heart-block","display_name":"congenital heart block","score":0.9879999756813049},{"id":"https://openalex.org/keywords/anti-ro-ssa-autoantibodies","display_name":"anti-Ro/SSA autoantibodies","score":0.7749999761581421},{"id":"https://openalex.org/keywords/transplacental-autoantibody-transfer","display_name":"transplacental autoantibody transfer","score":0.9319999814033508},{"id":"https://openalex.org/keywords/complete-heart-block","display_name":"complete heart block","score":0.6759999990463257},{"id":"https://openalex.org/keywords/fluorinated-steroids","display_name":"fluorinated steroids","score":0.7670000195503235},{"id":"https://openalex.org/keywords/beta-adrenergic-agonists","display_name":"beta-adrenergic agonists","score":0.7720000147819519},{"id":"https://openalex.org/keywords/plasmapheresis","display_name":"plasmapheresis","score":0.9089999794960022},{"id":"https://openalex.org/keywords/intravenous-immunoglobulin","display_name":"intravenous immunoglobulin","score":1.0},{"id":"https://openalex.org/keywords/hydroxychloroquine","display_name":"hydroxychloroquine","score":0.9980000257492065},{"id":"https://openalex.org/keywords/congenital-cardiomyopathy","display_name":"congenital cardiomyopathy","score":0.8330000042915344},{"id":"https://openalex.org/keywords/prenatal-prevention","display_name":"prenatal prevention","score":0.49900001287460327},{"id":"https://openalex.org/keywords/fetal-heart-rate","display_name":"fetal heart rate","score":0.3869999945163727}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9590775966644287},{"id":"https://openalex.org/C2778797674","wikidata":"https://www.wikidata.org/wiki/Q847583","display_name":"Cardiomyopathy","level":3,"score":0.6287727355957031},{"id":"https://openalex.org/C2776661526","wikidata":"https://www.wikidata.org/wiki/Q1361515","display_name":"Heart block","level":3,"score":0.605674684047699},{"id":"https://openalex.org/C2780074459","wikidata":"https://www.wikidata.org/wiki/Q389735","display_name":"Heart disease","level":2,"score":0.5911452770233154},{"id":"https://openalex.org/C201614185","wikidata":"https://www.wikidata.org/wiki/Q396833","display_name":"In utero","level":4,"score":0.5666921138763428},{"id":"https://openalex.org/C2779906218","wikidata":"https://www.wikidata.org/wiki/Q7834818","display_name":"Transplacental","level":5,"score":0.5634241700172424},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.5188013911247253},{"id":"https://openalex.org/C2779123688","wikidata":"https://www.wikidata.org/wiki/Q421094","display_name":"Hydroxychloroquine","level":5,"score":0.518156886100769},{"id":"https://openalex.org/C112672928","wikidata":"https://www.wikidata.org/wiki/Q239526","display_name":"Offspring","level":3,"score":0.4926674962043762},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46796542406082153},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.44513118267059326},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.3851156234741211},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.34951213002204895},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.34047985076904297},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.28706154227256775},{"id":"https://openalex.org/C2780040984","wikidata":"https://www.wikidata.org/wiki/Q79785","display_name":"Electrocardiography","level":2,"score":0.13156020641326904},{"id":"https://openalex.org/C2776953305","wikidata":"https://www.wikidata.org/wiki/Q1212935","display_name":"Placenta","level":4,"score":0.10662758350372314},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.0},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000318","descriptor_name":"Adrenergic beta-Agonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006327","descriptor_name":"Heart Block","qualifier_ui":"Q000151","qualifier_name":"congenital","is_major_topic":true},{"descriptor_ui":"D006327","descriptor_name":"Heart Block","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006327","descriptor_name":"Heart Block","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D006327","descriptor_name":"Heart Block","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006886","descriptor_name":"Hydroxychloroquine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000151","qualifier_name":"congenital","is_major_topic":true},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D010956","descriptor_name":"Plasmapheresis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011295","descriptor_name":"Prenatal Care","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011296","descriptor_name":"Prenatal Diagnosis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D013259","descriptor_name":"Steroids, Fluorinated","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D016756","descriptor_name":"Immunoglobulins, Intravenous","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D055502","descriptor_name":"Secondary Prevention","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1097/crd.0000000000000026","doi":"https://doi.org/10.1097/crd.0000000000000026","is_oa":false,"landing_page_url":"https://doi.org/10.1097/crd.0000000000000026","pdf_url":null,"source":{"id":"https://openalex.org/S173369630","display_name":"Cardiology in Review","issn_l":"1061-5377","issn":["1061-5377","1538-4683"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiology in Review","raw_type":"journal-article"},{"id":"pmid:25050975","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25050975","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiology in review","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4539276","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4539276","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Cardiol Rev","raw_type":"Text"},{"id":"pmh:oai:touroscholar.touro.edu:nymc_fac_pubs-8189","doi":null,"is_oa":false,"landing_page_url":"https://touroscholar.touro.edu/nymc_fac_pubs/7541","pdf_url":null,"source":{"id":"https://openalex.org/S4377196437","display_name":"Touro Scholar (Touro College)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I200437953","host_organization_name":"Touro College","host_organization_lineage":["https://openalex.org/I200437953"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"NYMC Faculty Publications","raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4539276","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4539276","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Cardiol Rev","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[{"id":"https://openalex.org/G239604856","display_name":"Maternal Autoantibodies: Pathogenesis of Neonatal Lupus","funder_award_id":"R37AR042455","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G5054178729","display_name":"Institutional Clinical and Translational Science Award","funder_award_id":"UL1TR000038","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6137382018","display_name":"Preventive Approach to Congenital Heart Block with Hydroxychloroquine (PATCH)","funder_award_id":"R03HD069986","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G7491831914","display_name":"Maternal Autoantibodies: Pathogenesis of Neonatal Lupus","funder_award_id":"R01AR042455","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G8260215778","display_name":null,"funder_award_id":"5R37 AR-42455-20","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":56,"referenced_works":["https://openalex.org/W90106534","https://openalex.org/W92943800","https://openalex.org/W100318658","https://openalex.org/W1845830920","https://openalex.org/W1921589044","https://openalex.org/W1926541123","https://openalex.org/W1964180982","https://openalex.org/W1970726851","https://openalex.org/W1974146458","https://openalex.org/W1974912691","https://openalex.org/W1978023215","https://openalex.org/W1980288586","https://openalex.org/W1981561109","https://openalex.org/W1983137347","https://openalex.org/W1995266188","https://openalex.org/W2001836991","https://openalex.org/W2012300598","https://openalex.org/W2012724329","https://openalex.org/W2014765668","https://openalex.org/W2015744687","https://openalex.org/W2019151860","https://openalex.org/W2022226947","https://openalex.org/W2029539614","https://openalex.org/W2031257102","https://openalex.org/W2040657208","https://openalex.org/W2046023606","https://openalex.org/W2047989346","https://openalex.org/W2048396249","https://openalex.org/W2054992677","https://openalex.org/W2062589259","https://openalex.org/W2062687834","https://openalex.org/W2062944200","https://openalex.org/W2068019125","https://openalex.org/W2068029628","https://openalex.org/W2071010256","https://openalex.org/W2071510385","https://openalex.org/W2079302990","https://openalex.org/W2079355126","https://openalex.org/W2080285185","https://openalex.org/W2088079128","https://openalex.org/W2089219446","https://openalex.org/W2097558397","https://openalex.org/W2100719470","https://openalex.org/W2113542513","https://openalex.org/W2116548019","https://openalex.org/W2124728272","https://openalex.org/W2125111321","https://openalex.org/W2133925071","https://openalex.org/W2137600365","https://openalex.org/W2145904199","https://openalex.org/W2155848427","https://openalex.org/W2162437395","https://openalex.org/W2323762480","https://openalex.org/W2338721595","https://openalex.org/W2410197779","https://openalex.org/W2413769308"],"related_works":["https://openalex.org/W2410955152","https://openalex.org/W7204902875","https://openalex.org/W4394754941","https://openalex.org/W2018449091","https://openalex.org/W3045583390","https://openalex.org/W1691634232","https://openalex.org/W4391689788","https://openalex.org/W90106534","https://openalex.org/W4312572937","https://openalex.org/W1134477563"],"abstract_inverted_index":{"Transplacental":[0],"transfer":[1],"of":[2,26,33,101,107,125,154,178,189,208],"maternal":[3],"anti-Ro":[4],"and/or":[5],"anti-La":[6],"autoantibodies":[7],"can":[8],"result":[9],"in":[10,36,58,67,85,104,109,121,134,139,156,186,193,211,227],"fetal":[11,118],"cardiac":[12,21,34,110,157,173,209],"disease,":[13],"including":[14],"congenital":[15],"heart":[16,56,69,119],"block":[17,57,70],"and":[18,45,71,128,195,218],"cardiomyopathy,":[19],"called":[20],"neonatal":[22],"lupus":[23],"(NL).":[24],"Thousands":[25],"women":[27],"are":[28,48,96,133],"faced":[29],"with":[30,42,141,213],"the":[31,74,99,105,152,187,206],"risk":[32],"NL":[35,158,174,210],"their":[37],"offspring,":[38],"which":[39],"is":[40,223],"associated":[41,190],"significant":[43],"morbidity":[44],"mortality.":[46],"There":[47],"no":[49],"known":[50],"therapies":[51],"to":[52,116,171,229],"permanently":[53],"reverse":[54],"third-degree":[55],"NL,":[59],"although":[60,88,181],"several":[61],"treatments":[62],"have":[63,82,113,159,200],"shown":[64,83,170,184,201],"some":[65],"effectiveness":[66,185],"incomplete":[68],"disease":[72],"beyond":[73],"atrioventricular":[75],"node.":[76],"Fluorinated":[77],"steroids":[78,103],"taken":[79],"during":[80],"pregnancy":[81],"benefit":[84],"these":[86],"situations,":[87],"adverse":[89],"effects":[90],"may":[91,145,204],"be":[92],"concerning.":[93],"Published":[94],"data":[95],"discordant":[97],"on":[98,131],"efficacy":[100],"fluorinated":[102],"prevention":[106],"mortality":[108,132],"NL.":[111],"\u03b2-agonists":[112],"been":[114,160],"used":[115,138],"increase":[117],"rates":[120],"utero.":[122],"The":[123],"endurance":[124],"\u03b2-agonist":[126],"effect":[127],"its":[129,163],"impact":[130],"question,":[135],"but":[136],"when":[137],"combination":[140],"other":[142],"therapies,":[143],"they":[144],"provide":[146],"benefit.":[147],"No":[148],"controlled":[149],"experiments":[150],"regarding":[151],"use":[153],"plasmapheresis":[155],"performed,":[161],"despite":[162],"theoretical":[164],"benefits.":[165],"Intravenous":[166],"immunoglobulin":[167],"was":[168],"not":[169],"prevent":[172,205],"at":[175],"a":[176,214,219],"dose":[177],"400":[179],"mg/kg,":[180],"it":[182],"has":[183],"treatment":[188],"cardiomyopathy":[191],"both":[192],"utero":[194],"after":[196],"birth.":[197],"Retrospective":[198],"studies":[199],"that":[202],"hydroxychloroquine":[203],"recurrence":[207],"families":[212],"previously":[215],"affected":[216],"child,":[217],"prospective":[220],"open-label":[221],"trial":[222],"currently":[224],"recruiting":[225],"patients":[226],"order":[228],"fully":[230],"evaluate":[231],"this":[232],"relationship.":[233]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":16},{"year":2018,"cited_by_count":10},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":4},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}