{"id":"https://openalex.org/W2052226242","doi":"https://doi.org/10.1086/674795","title":"Epidemiological Feedbacks Affect Evolutionary Emergence of Pathogens","display_name":"Epidemiological Feedbacks Affect Evolutionary Emergence of Pathogens","publication_year":2014,"publication_date":"2014-02-12","ids":{"openalex":"https://openalex.org/W2052226242","doi":"https://doi.org/10.1086/674795","mag":"2052226242","pmid":"https://pubmed.ncbi.nlm.nih.gov/24642501"},"language":"en","primary_location":{"id":"doi:10.1086/674795","doi":"https://doi.org/10.1086/674795","is_oa":true,"landing_page_url":"https://doi.org/10.1086/674795","pdf_url":null,"source":{"id":"https://openalex.org/S122176235","display_name":"The American Naturalist","issn_l":"0003-0147","issn":["0003-0147","1537-5323"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-3","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315672","host_organization_name":"University of Chicago Press","host_organization_lineage":["https://openalex.org/P4310315672","https://openalex.org/P4310315690"],"host_organization_lineage_names":["University of Chicago Press","University of Chicago"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Naturalist","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1086/674795","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000460408","display_name":"Matthew Hartfield","orcid":"https://orcid.org/0000-0001-6941-0647","observed_orcids":["https://orcid.org/0000-0001-6941-0647"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210087127","display_name":"Maladies Infectieuses et Vecteurs: \u00c9cologie, G\u00e9n\u00e9tique, \u00c9volution et Contr\u00f4le","ror":"https://ror.org/00357kh21","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I2802818602","https://openalex.org/I4210087127","https://openalex.org/I4210088668","https://openalex.org/I4210090127","https://openalex.org/I4210107625","https://openalex.org/I4210131494","https://openalex.org/I4210166444"]},{"id":"https://openalex.org/I4210166444","display_name":"Institut de Recherche pour le D\u00e9veloppement","ror":"https://ror.org/05q3vnk25","country_code":"FR","type":"government","lineage":["https://openalex.org/I2802818602","https://openalex.org/I4210090127","https://openalex.org/I4210131494","https://openalex.org/I4210166444"]},{"id":"https://openalex.org/I4387153574","display_name":"Universit\u00e9 Montpellier 1","ror":"https://ror.org/0227fbx80","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307","https://openalex.org/I4387153574"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Matthew Hartfield","raw_affiliation_strings":["Laboratoire Maladies Infectieuses et Vecteurs: Ecologie, G\u00e9n\u00e9tique, Evolution et Contr\u00f4le (Unit\u00e9 Mixte de Recherche CNRS 5290, Institut de Recherche pour le D\u00e9veloppement [IRD] 224, Universities of Montpellier 1 and 2), 911 Avenue Agropolis, B.P. 64501, 34394 Montpellier Cedex 5, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire Maladies Infectieuses et Vecteurs: Ecologie, G\u00e9n\u00e9tique, Evolution et Contr\u00f4le (Unit\u00e9 Mixte de Recherche CNRS 5290, Institut de Recherche pour le D\u00e9veloppement [IRD] 224, Universities of Montpellier 1 and 2), 911 Avenue Agropolis, B.P. 64501, 34394 Montpellier Cedex 5, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210087127","https://openalex.org/I4210166444","https://openalex.org/I4387153574"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083653654","display_name":"Samuel Alizon","orcid":"https://orcid.org/0000-0002-0779-9543","observed_orcids":["https://orcid.org/0000-0002-0779-9543"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210087127","display_name":"Maladies Infectieuses et Vecteurs: \u00c9cologie, G\u00e9n\u00e9tique, \u00c9volution et Contr\u00f4le","ror":"https://ror.org/00357kh21","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I2802818602","https://openalex.org/I4210087127","https://openalex.org/I4210088668","https://openalex.org/I4210090127","https://openalex.org/I4210107625","https://openalex.org/I4210131494","https://openalex.org/I4210166444"]},{"id":"https://openalex.org/I4210166444","display_name":"Institut de Recherche pour le D\u00e9veloppement","ror":"https://ror.org/05q3vnk25","country_code":"FR","type":"government","lineage":["https://openalex.org/I2802818602","https://openalex.org/I4210090127","https://openalex.org/I4210131494","https://openalex.org/I4210166444"]},{"id":"https://openalex.org/I4387153574","display_name":"Universit\u00e9 Montpellier 1","ror":"https://ror.org/0227fbx80","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307","https://openalex.org/I4387153574"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Samuel Alizon","raw_affiliation_strings":["Laboratoire Maladies Infectieuses et Vecteurs: Ecologie, G\u00e9n\u00e9tique, Evolution et Contr\u00f4le (Unit\u00e9 Mixte de Recherche  CNRS 5290,  Institut de Recherche pour le D\u00e9veloppement [IRD] 224, Universities of Montpellier 1 and 2), 911 Avenue Agropolis, B.P. 64501, 34394 Montpellier Cedex 5, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire Maladies Infectieuses et Vecteurs: Ecologie, G\u00e9n\u00e9tique, Evolution et Contr\u00f4le (Unit\u00e9 Mixte de Recherche  CNRS 5290,  Institut de Recherche pour le D\u00e9veloppement [IRD] 224, Universities of Montpellier 1 and 2), 911 Avenue Agropolis, B.P. 64501, 34394 Montpellier Cedex 5, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210087127","https://openalex.org/I4210166444","https://openalex.org/I4387153574"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5000460408","https://openalex.org/A5083653654"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210087127","https://openalex.org/I4210166444","https://openalex.org/I4387153574"],"apc_list":null,"apc_paid":null,"fwci":2.4423,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.87761871,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"183","issue":"4","first_page":"E105","last_page":"E117"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10482","display_name":"Mathematical and Theoretical Epidemiology and Ecology Models","score":0.9442999958992004,"subfield":{"id":"https://openalex.org/subfields/2604","display_name":"Applied Mathematics"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10482","display_name":"Mathematical and Theoretical Epidemiology and Ecology Models","score":0.9442999958992004,"subfield":{"id":"https://openalex.org/subfields/2604","display_name":"Applied Mathematics"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11764","display_name":"Evolution and Genetic Dynamics","score":0.041099999099969864,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11581","display_name":"Viral Infections and Outbreaks Research","score":0.0038999998942017555,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pathogen-emergence","display_name":"pathogen emergence","score":0.8690000176429749},{"id":"https://openalex.org/keywords/mutation","display_name":"genetic mutations","score":0.4129999876022339},{"id":"https://openalex.org/keywords/evolutionary-emergence","display_name":"evolutionary emergence","score":0.4230000078678131},{"id":"https://openalex.org/keywords/chikungunya-virus","display_name":"chikungunya virus","score":0.9110000133514404},{"id":"https://openalex.org/keywords/epidemic-forecasting","display_name":"epidemic forecasting","score":0.3569999933242798}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7619740962982178},{"id":"https://openalex.org/C2778022156","wikidata":"https://www.wikidata.org/wiki/Q576145","display_name":"Strain (injury)","level":2,"score":0.653303861618042},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.611972987651825},{"id":"https://openalex.org/C204264503","wikidata":"https://www.wikidata.org/wiki/Q901464","display_name":"Basic reproduction number","level":3,"score":0.5845206379890442},{"id":"https://openalex.org/C116675565","wikidata":"https://www.wikidata.org/wiki/Q3241045","display_name":"Outbreak","level":2,"score":0.5843784213066101},{"id":"https://openalex.org/C52103748","wikidata":"https://www.wikidata.org/wiki/Q2624927","display_name":"Susceptible individual","level":3,"score":0.5218228697776794},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.5174258947372437},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5000104904174805},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.46110066771507263},{"id":"https://openalex.org/C98638677","wikidata":"https://www.wikidata.org/wiki/Q2067051","display_name":"Mutation rate","level":3,"score":0.45856866240501404},{"id":"https://openalex.org/C2776460866","wikidata":"https://www.wikidata.org/wiki/Q170065","display_name":"Pathogen","level":2,"score":0.41888657212257385},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.32944774627685547},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.25329816341400146},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.22818204760551453},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11605262756347656},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004196","descriptor_name":"Disease Outbreaks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005075","descriptor_name":"Biological Evolution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007195","descriptor_name":"Indian Ocean Islands","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018562","descriptor_name":"Disease Transmission, Infectious","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D021821","descriptor_name":"Communicable Diseases, Emerging","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D065632","descriptor_name":"Chikungunya Fever","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1086/674795","doi":"https://doi.org/10.1086/674795","is_oa":true,"landing_page_url":"https://doi.org/10.1086/674795","pdf_url":null,"source":{"id":"https://openalex.org/S122176235","display_name":"The American Naturalist","issn_l":"0003-0147","issn":["0003-0147","1537-5323"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-3","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315672","host_organization_name":"University of Chicago Press","host_organization_lineage":["https://openalex.org/P4310315672","https://openalex.org/P4310315690"],"host_organization_lineage_names":["University of Chicago Press","University of Chicago"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Naturalist","raw_type":"journal-article"},{"id":"pmid:24642501","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24642501","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American naturalist","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-01567911v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.science/hal-01567911","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The American Naturalist, 2014, 183 (4), pp.E105-17. &#x27E8;10.1086/674795&#x27E9;","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1086/674795","doi":"https://doi.org/10.1086/674795","is_oa":true,"landing_page_url":"https://doi.org/10.1086/674795","pdf_url":null,"source":{"id":"https://openalex.org/S122176235","display_name":"The American Naturalist","issn_l":"0003-0147","issn":["0003-0147","1537-5323"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-3","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315672","host_organization_name":"University of Chicago Press","host_organization_lineage":["https://openalex.org/P4310315672","https://openalex.org/P4310315690"],"host_organization_lineage_names":["University of Chicago Press","University of Chicago"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Naturalist","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.504800021648407,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320893","display_name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","ror":"https://ror.org/02vjkv261"},{"id":"https://openalex.org/F4320322892","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":67,"referenced_works":["https://openalex.org/W75814757","https://openalex.org/W207440351","https://openalex.org/W1591710988","https://openalex.org/W1606697907","https://openalex.org/W1726084382","https://openalex.org/W1855857669","https://openalex.org/W1971606219","https://openalex.org/W1978517172","https://openalex.org/W1981402102","https://openalex.org/W1984332517","https://openalex.org/W1985726977","https://openalex.org/W1986992441","https://openalex.org/W1989530362","https://openalex.org/W1998309113","https://openalex.org/W2010365240","https://openalex.org/W2015426605","https://openalex.org/W2020891730","https://openalex.org/W2021477184","https://openalex.org/W2021524494","https://openalex.org/W2023690349","https://openalex.org/W2026090600","https://openalex.org/W2034377840","https://openalex.org/W2034548473","https://openalex.org/W2045391589","https://openalex.org/W2055601403","https://openalex.org/W2057132961","https://openalex.org/W2062210712","https://openalex.org/W2069251911","https://openalex.org/W2070324879","https://openalex.org/W2076599380","https://openalex.org/W2078447116","https://openalex.org/W2084924279","https://openalex.org/W2085366875","https://openalex.org/W2091934799","https://openalex.org/W2096242086","https://openalex.org/W2097575621","https://openalex.org/W2099449559","https://openalex.org/W2102586506","https://openalex.org/W2103230759","https://openalex.org/W2104283176","https://openalex.org/W2104595316","https://openalex.org/W2105656400","https://openalex.org/W2118726788","https://openalex.org/W2120984832","https://openalex.org/W2127427126","https://openalex.org/W2128737288","https://openalex.org/W2130597146","https://openalex.org/W2133250947","https://openalex.org/W2135242492","https://openalex.org/W2136281516","https://openalex.org/W2138838635","https://openalex.org/W2145610587","https://openalex.org/W2148348477","https://openalex.org/W2150236092","https://openalex.org/W2154169270","https://openalex.org/W2155418451","https://openalex.org/W2155670634","https://openalex.org/W2156205184","https://openalex.org/W2165506056","https://openalex.org/W2166022262","https://openalex.org/W2575306271","https://openalex.org/W2802526971","https://openalex.org/W3102202026","https://openalex.org/W3141316455","https://openalex.org/W4251304755","https://openalex.org/W4253414868","https://openalex.org/W4291439952"],"related_works":["https://openalex.org/W6892158375","https://openalex.org/W4399119957","https://openalex.org/W2154169270","https://openalex.org/W7095841392","https://openalex.org/W2073800139","https://openalex.org/W6968507199","https://openalex.org/W2171590867","https://openalex.org/W2096242086","https://openalex.org/W2952345745","https://openalex.org/W6948888286"],"abstract_inverted_index":{"The":[0],"evolutionary":[1],"emergence":[2,55,100,115,146,169,181],"of":[3,52,81,101,113,133,148,170,183,208],"new":[4],"pathogens":[5],"via":[6],"mutation":[7,30],"poses":[8],"a":[9,24,58,68,79,111,141],"considerable":[10],"risk":[11],"to":[12,106,166,192],"human":[13],"and":[14,127,177],"animal":[15],"populations.":[16],"Most":[17],"previous":[18],"studies":[19],"have":[20],"investigated":[21],"cases":[22],"where":[23,57],"potentially":[25],"pandemic":[26],"strain":[27,35,61,71,91,139,186],"emerges":[28],"though":[29],"from":[31],"an":[32,45],"initial":[33],"maladapted":[34],"(i.e.,":[36],"its":[37],"basic":[38],"reproductive":[39,159],"ratio":[40],"R0":[41,63,73],"<":[42],"1).":[43,75],"However,":[44],"alternative":[46],"(and":[47],"arguably":[48],"more":[49],"likely)":[50],"cause":[51],"novel":[53],"pathogen":[54,114],"is":[56,86],"\"weakly":[59],"adapted\"":[60],"(with":[62,72],"\u2248":[64],"1)":[65],"mutates":[66],"into":[67,118,212],"strongly":[69],"adapted":[70],"\u226b":[74],"In":[76],"this":[77,96],"case,":[78],"proportion":[80],"the":[82,89,94,122,130,137,145,149,158,167,180,184,206],"host":[83],"susceptible":[84,123,134,196],"population":[85,124,210],"removed":[87],"as":[88],"first":[90,138],"spreads,":[92],"but":[93],"impact":[95],"feedback":[97],"has":[98,104,140],"on":[99,144,173],"mutated":[102,150,185],"strains":[103],"yet":[105],"be":[107],"quantified.":[108],"We":[109],"produce":[110],"model":[112,165],"that":[116,129,153,179,195],"takes":[117],"account":[119,213],"changes":[120],"in":[121],"over":[125],"time":[126],"find":[128],"ongoing":[131],"depletion":[132,197],"individuals":[135],"by":[136,155],"drastic":[142],"effect":[143],"probability":[147,182],"strain,":[151],"above":[152],"assumed":[154],"just":[156],"scaling":[157],"ratio.":[160],"Finally,":[161],"we":[162],"apply":[163],"our":[164],"documented":[168],"Chikungunya":[171],"virus":[172],"La":[174],"R\u00e9union":[175],"Island":[176],"demonstrate":[178],"was":[187],"reduced":[188],"approximately":[189],"10-fold,":[190],"compared":[191],"models":[193],"assuming":[194],"would":[198],"not":[199],"affect":[200],"outbreak":[201],"probability.":[202],"These":[203],"results":[204],"highlight":[205],"importance":[207],"taking":[209],"feedbacks":[211],"when":[214],"predicting":[215],"disease":[216],"emergence.":[217]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":4}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}
