{"id":"https://openalex.org/W2051960177","doi":"https://doi.org/10.1002/pmic.201100072","title":"Temporal proteomic profile of memory consolidation in the rat hippocampal dentate gyrus","display_name":"Temporal proteomic profile of memory consolidation in the rat hippocampal dentate gyrus","publication_year":2011,"publication_date":"2011-09-01","ids":{"openalex":"https://openalex.org/W2051960177","doi":"https://doi.org/10.1002/pmic.201100072","mag":"2051960177","pmid":"https://pubmed.ncbi.nlm.nih.gov/22002935"},"language":"en","primary_location":{"id":"doi:10.1002/pmic.201100072","doi":"https://doi.org/10.1002/pmic.201100072","is_oa":false,"landing_page_url":"https://doi.org/10.1002/pmic.201100072","pdf_url":null,"source":{"id":"https://openalex.org/S182655450","display_name":"PROTEOMICS","issn_l":"1615-9853","issn":["1615-9853","1615-9861"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PROTEOMICS","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041102359","display_name":"Marco P. Monopoli","orcid":"https://orcid.org/0000-0002-2035-6894","observed_orcids":["https://orcid.org/0000-0002-2035-6894"]},"institutions":[{"id":"https://openalex.org/I100930933","display_name":"University College Dublin","ror":"https://ror.org/05m7pjf47","country_code":"IE","type":"education","lineage":["https://openalex.org/I100930933"]}],"countries":["IE"],"is_corresponding":true,"raw_author_name":"Marco P. Monopoli","raw_affiliation_strings":["Applied Neurotherapeutics Research Group, UCD School of Biomolecular and Biomedical Science, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland. Marco.Monopoli@ucd.ie","Applied Neurotherapeutics Research Group, UCD School of Biomolecular and Biomedical Science, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland","Proteome Research Centre, UCD Conway Institute of Biomolecular and Biomedical Research, School of Medicine and Medical Science, University College Dublin, Belfield, Dublin, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Applied Neurotherapeutics Research Group, UCD School of Biomolecular and Biomedical Science, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland. Marco.Monopoli@ucd.ie","institution_ids":["https://openalex.org/I100930933"]},{"raw_affiliation_string":"Applied Neurotherapeutics Research Group, UCD School of Biomolecular and Biomedical Science, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland","institution_ids":["https://openalex.org/I100930933"]},{"raw_affiliation_string":"Proteome Research Centre, UCD Conway Institute of Biomolecular and Biomedical Research, School of Medicine and Medical Science, University College Dublin, Belfield, Dublin, Ireland","institution_ids":["https://openalex.org/I100930933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090324798","display_name":"Michelle Nic Raghnaill","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100930933","display_name":"University College Dublin","ror":"https://ror.org/05m7pjf47","country_code":"IE","type":"education","lineage":["https://openalex.org/I100930933"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Michelle Nic Raghnaill","raw_affiliation_strings":["Applied Neurotherapeutics Research Group, UCD School of Biomolecular and Biomedical Science, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Applied Neurotherapeutics Research Group, UCD School of Biomolecular and Biomedical Science, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland","institution_ids":["https://openalex.org/I100930933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022092004","display_name":"Jennifer S. Loscher","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100930933","display_name":"University College Dublin","ror":"https://ror.org/05m7pjf47","country_code":"IE","type":"education","lineage":["https://openalex.org/I100930933"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Jennifer S. Loscher","raw_affiliation_strings":["Applied Neurotherapeutics Research Group, UCD School of Biomolecular and Biomedical Science, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Applied Neurotherapeutics Research Group, UCD School of Biomolecular and Biomedical Science, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland","institution_ids":["https://openalex.org/I100930933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050934210","display_name":"Niamh C. O\u2019Sullivan","orcid":"https://orcid.org/0000-0002-8244-8145","observed_orcids":["https://orcid.org/0000-0002-8244-8145"]},"institutions":[{"id":"https://openalex.org/I100930933","display_name":"University College Dublin","ror":"https://ror.org/05m7pjf47","country_code":"IE","type":"education","lineage":["https://openalex.org/I100930933"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Niamh C. O'Sullivan","raw_affiliation_strings":["Applied Neurotherapeutics Research Group, UCD School of Biomolecular and Biomedical Science, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Applied Neurotherapeutics Research Group, UCD School of Biomolecular and Biomedical Science, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland","institution_ids":["https://openalex.org/I100930933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010982846","display_name":"Menelas N. Pangalos","orcid":"https://orcid.org/0000-0001-9783-0956","observed_orcids":["https://orcid.org/0000-0001-9783-0956"]},"institutions":[{"id":"https://openalex.org/I105036370","display_name":"AstraZeneca (United Kingdom)","ror":"https://ror.org/04r9x1a08","country_code":"GB","type":"company","lineage":["https://openalex.org/I105036370"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Menelas N. Pangalos","raw_affiliation_strings":["Innovative Medicines AstraZeneca, Mereside, Alderley Park, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Innovative Medicines AstraZeneca, Mereside, Alderley Park, UK","institution_ids":["https://openalex.org/I105036370"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064017219","display_name":"Robert H. Ring","orcid":"https://orcid.org/0000-0002-7037-4409","observed_orcids":["https://orcid.org/0000-0002-7037-4409"]},"institutions":[{"id":"https://openalex.org/I180857899","display_name":"Pfizer (United States)","ror":"https://ror.org/01xdqrp08","country_code":"US","type":"company","lineage":["https://openalex.org/I180857899"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert H. Ring","raw_affiliation_strings":["Autism Research Unit, Pfizer Worldwide Research & Development, Groton, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Autism Research Unit, Pfizer Worldwide Research & Development, Groton, CT, USA","institution_ids":["https://openalex.org/I180857899"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090674996","display_name":"David von Schack","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180857899","display_name":"Pfizer (United States)","ror":"https://ror.org/01xdqrp08","country_code":"US","type":"company","lineage":["https://openalex.org/I180857899"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David von Schack","raw_affiliation_strings":["Inflammation Research Unit, Pfizer Worldwide Research & Development, Cambridge, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inflammation Research Unit, Pfizer Worldwide Research & Development, Cambridge, MA, USA","institution_ids":["https://openalex.org/I180857899"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024617116","display_name":"Michael James Dunn","orcid":"https://orcid.org/0000-0003-4633-5466","observed_orcids":["https://orcid.org/0000-0003-4633-5466"]},"institutions":[{"id":"https://openalex.org/I100930933","display_name":"University College Dublin","ror":"https://ror.org/05m7pjf47","country_code":"IE","type":"education","lineage":["https://openalex.org/I100930933"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Michael J. Dunn","raw_affiliation_strings":["Proteome Research Centre, UCD Conway Institute of Biomolecular and Biomedical Research, School of Medicine and Medical Science, University College Dublin, Belfield, Dublin, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Proteome Research Centre, UCD Conway Institute of Biomolecular and Biomedical Research, School of Medicine and Medical Science, University College Dublin, Belfield, Dublin, Ireland","institution_ids":["https://openalex.org/I100930933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102951033","display_name":"Ciaran M. Regan","orcid":"https://orcid.org/0009-0001-8377-7231","observed_orcids":["https://orcid.org/0009-0001-8377-7231"]},"institutions":[{"id":"https://openalex.org/I100930933","display_name":"University College Dublin","ror":"https://ror.org/05m7pjf47","country_code":"IE","type":"education","lineage":["https://openalex.org/I100930933"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Ciaran M. Regan","raw_affiliation_strings":["Applied Neurotherapeutics Research Group, UCD School of Biomolecular and Biomedical Science, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Applied Neurotherapeutics Research Group, UCD School of Biomolecular and Biomedical Science, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland","institution_ids":["https://openalex.org/I100930933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074326062","display_name":"Stephen R. Pennington","orcid":"https://orcid.org/0000-0001-7529-1015","observed_orcids":["https://orcid.org/0000-0001-7529-1015"]},"institutions":[{"id":"https://openalex.org/I100930933","display_name":"University College Dublin","ror":"https://ror.org/05m7pjf47","country_code":"IE","type":"education","lineage":["https://openalex.org/I100930933"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Stephen Pennington","raw_affiliation_strings":["Proteome Research Centre, UCD Conway Institute of Biomolecular and Biomedical Research, School of Medicine and Medical Science, University College Dublin, Belfield, Dublin, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Proteome Research Centre, UCD Conway Institute of Biomolecular and Biomedical Research, School of Medicine and Medical Science, University College Dublin, Belfield, Dublin, Ireland","institution_ids":["https://openalex.org/I100930933"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081630454","display_name":"Keith J. Murphy","orcid":"https://orcid.org/0000-0002-8865-0467","observed_orcids":["https://orcid.org/0000-0002-8865-0467"]},"institutions":[{"id":"https://openalex.org/I100930933","display_name":"University College Dublin","ror":"https://ror.org/05m7pjf47","country_code":"IE","type":"education","lineage":["https://openalex.org/I100930933"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Keith J. Murphy","raw_affiliation_strings":["Applied Neurotherapeutics Research Group, UCD School of Biomolecular and Biomedical Science, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Applied Neurotherapeutics Research Group, UCD School of Biomolecular and Biomedical Science, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland","institution_ids":["https://openalex.org/I100930933"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5041102359"],"corresponding_institution_ids":["https://openalex.org/I100930933"],"apc_list":{"value":4650,"currency":"USD","value_usd":4650},"apc_paid":null,"fwci":1.2642,"has_fulltext":false,"cited_by_count":37,"citation_normalized_percentile":{"value":0.77032146,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"11","issue":"21","first_page":"4189","last_page":"4201"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.005900000222027302,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/memory-consolidation","display_name":"memory consolidation","score":0.9959999918937683},{"id":"https://openalex.org/keywords/dentate-gyrus","display_name":"dentate gyrus","score":0.9570000171661377},{"id":"https://openalex.org/keywords/spatial-learning","display_name":"spatial learning","score":0.8389999866485596},{"id":"https://openalex.org/keywords/de-novo-protein-synthesis","display_name":"de novo protein synthesis","score":0.7630000114440918},{"id":"https://openalex.org/keywords/synaptic-plasticity","display_name":"synaptic plasticity","score":0.7319999933242798},{"id":"https://openalex.org/keywords/cytoskeletal-proteins","display_name":"cytoskeletal proteins","score":0.8529999852180481},{"id":"https://openalex.org/keywords/actin","display_name":"actin","score":0.6159999966621399},{"id":"https://openalex.org/keywords/tubulin","display_name":"tubulin","score":0.9950000047683716},{"id":"https://openalex.org/keywords/intermediate-filaments","display_name":"intermediate filaments","score":0.9079999923706055},{"id":"https://openalex.org/keywords/proteasomal-degradation","display_name":"proteasomal degradation","score":0.949999988079071},{"id":"https://openalex.org/keywords/prealbumin","display_name":"prealbumin","score":0.9330000281333923},{"id":"https://openalex.org/keywords/serum-albumin","display_name":"serum albumin","score":0.9980000257492065},{"id":"https://openalex.org/keywords/retinoic-acid","display_name":"retinoic acid","score":0.972000002861023},{"id":"https://openalex.org/keywords/thyroid-hormones","display_name":"thyroid hormones","score":0.8989999890327454}],"concepts":[{"id":"https://openalex.org/C2776464000","wikidata":"https://www.wikidata.org/wiki/Q545787","display_name":"Dentate gyrus","level":3,"score":0.782782793045044},{"id":"https://openalex.org/C48455012","wikidata":"https://www.wikidata.org/wiki/Q2892593","display_name":"Memory consolidation","level":3,"score":0.7136393785476685},{"id":"https://openalex.org/C98229152","wikidata":"https://www.wikidata.org/wiki/Q1551556","display_name":"Synaptic plasticity","level":3,"score":0.6772303581237793},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.6128944754600525},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5359262824058533},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5099366903305054},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4714440107345581},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.45105400681495667},{"id":"https://openalex.org/C25274449","wikidata":"https://www.wikidata.org/wiki/Q1805481","display_name":"Long-term potentiation","level":3,"score":0.4303521513938904},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2867862582206726},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.08335995674133301}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008568","descriptor_name":"Memory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010750","descriptor_name":"Phosphoproteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010750","descriptor_name":"Phosphoproteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011228","descriptor_name":"Prealbumin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011228","descriptor_name":"Prealbumin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012709","descriptor_name":"Serum Albumin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012709","descriptor_name":"Serum Albumin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018782","descriptor_name":"Maze Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018891","descriptor_name":"Dentate Gyrus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051017","descriptor_name":"Apoptosis Regulatory Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057825","descriptor_name":"Two-Dimensional Difference Gel Electrophoresis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/pmic.201100072","doi":"https://doi.org/10.1002/pmic.201100072","is_oa":false,"landing_page_url":"https://doi.org/10.1002/pmic.201100072","pdf_url":null,"source":{"id":"https://openalex.org/S182655450","display_name":"PROTEOMICS","issn_l":"1615-9853","issn":["1615-9853","1615-9861"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PROTEOMICS","raw_type":"journal-article"},{"id":"pmid:22002935","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22002935","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proteomics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":87,"referenced_works":["https://openalex.org/W249845531","https://openalex.org/W1512287707","https://openalex.org/W1551114423","https://openalex.org/W1564192489","https://openalex.org/W1598177992","https://openalex.org/W1964259998","https://openalex.org/W1966225158","https://openalex.org/W1966316797","https://openalex.org/W1966901093","https://openalex.org/W1968162860","https://openalex.org/W1972310415","https://openalex.org/W1976405146","https://openalex.org/W1977019885","https://openalex.org/W1977950302","https://openalex.org/W1981458288","https://openalex.org/W1981554486","https://openalex.org/W1981918245","https://openalex.org/W1982363093","https://openalex.org/W1987796972","https://openalex.org/W1989023227","https://openalex.org/W1999170657","https://openalex.org/W1999318440","https://openalex.org/W2002734542","https://openalex.org/W2003906235","https://openalex.org/W2005065580","https://openalex.org/W2005077388","https://openalex.org/W2005349878","https://openalex.org/W2005805156","https://openalex.org/W2005895852","https://openalex.org/W2006894381","https://openalex.org/W2006965909","https://openalex.org/W2010762857","https://openalex.org/W2015592781","https://openalex.org/W2015785058","https://openalex.org/W2018971191","https://openalex.org/W2019746426","https://openalex.org/W2022821750","https://openalex.org/W2028305875","https://openalex.org/W2029333902","https://openalex.org/W2036707049","https://openalex.org/W2042652949","https://openalex.org/W2043676311","https://openalex.org/W2043686997","https://openalex.org/W2051974440","https://openalex.org/W2054920080","https://openalex.org/W2059877441","https://openalex.org/W2061733344","https://openalex.org/W2062313867","https://openalex.org/W2063120457","https://openalex.org/W2065682838","https://openalex.org/W2069705491","https://openalex.org/W2073301114","https://openalex.org/W2078594804","https://openalex.org/W2078853671","https://openalex.org/W2082094926","https://openalex.org/W2084252221","https://openalex.org/W2086236919","https://openalex.org/W2091064369","https://openalex.org/W2091395024","https://openalex.org/W2091845852","https://openalex.org/W2094356889","https://openalex.org/W2097681411","https://openalex.org/W2099347739","https://openalex.org/W2100492545","https://openalex.org/W2101681445","https://openalex.org/W2110715491","https://openalex.org/W2113247978","https://openalex.org/W2113356346","https://openalex.org/W2118612617","https://openalex.org/W2120828918","https://openalex.org/W2120862662","https://openalex.org/W2121918549","https://openalex.org/W2128635872","https://openalex.org/W2133083344","https://openalex.org/W2134010906","https://openalex.org/W2147065485","https://openalex.org/W2156645057","https://openalex.org/W2158617540","https://openalex.org/W2160431149","https://openalex.org/W2163815564","https://openalex.org/W2164198678","https://openalex.org/W2164751282","https://openalex.org/W2167436769","https://openalex.org/W2168127005","https://openalex.org/W2169294911","https://openalex.org/W2490208091","https://openalex.org/W7097323753"],"related_works":["https://openalex.org/W2117847158","https://openalex.org/W2221098107","https://openalex.org/W7198678680","https://openalex.org/W2520688056","https://openalex.org/W2005077388","https://openalex.org/W2081363456","https://openalex.org/W2181866388","https://openalex.org/W2156645057","https://openalex.org/W2062815625","https://openalex.org/W2094316198"],"abstract_inverted_index":{"Information":[0],"storage":[1],"in":[2,46,56,75,102,157,167,178,220,234,249],"the":[3,7,20,57,76,114,119,143,168,173,192,222,235,250],"brain":[4],"depends":[5],"on":[6],"ability":[8],"of":[9,31,80,87,108,113,121,142,175,185,191,224],"neurons":[10],"to":[11,51,126],"alter":[12],"synaptic":[13,23,159,231],"connectivity":[14],"within":[15],"key":[16,183,230],"circuitries":[17],"such":[18],"as":[19],"hippocampus.":[21],"Memory-associated":[22],"plasticity":[24],"is":[25,101],"mediated":[26],"by":[27],"a":[28,155,182],"temporal":[29],"cascade":[30],"de":[32],"novo":[33],"protein":[34,38,54,88,163,195,245],"synthesis":[35],"and":[36,95,99,136,206,227],"altered":[37],"processing.":[39],"Here,":[40],"we":[41],"have":[42],"used":[43],"two-dimensional":[44],"difference":[45],"gel":[47],"electrophoresis":[48],"(2-D":[49],"DIGE)":[50],"investigate":[52],"memory-specific":[53],"changes":[55,197],"hippocampal":[58],"dentate":[59],"gyrus":[60],"at":[61,93,151,209],"increasing":[62,221],"times":[63,152],"following":[64],"spatial":[65,81,253],"learning.":[66],"We":[67],"identified":[68],"42":[69],"proteins":[70,116,123,141,203],"that":[71,118,153,214],"were":[72,91,148,198],"significantly":[73],"regulated":[74,122,150],"first":[77],"24":[78],"h":[79,97,211],"memory":[82,254],"consolidation.":[83,255],"Two":[84],"distinct":[85],"waves":[86],"expression":[89,196],"regulation":[90],"evident,":[92],"3":[94],"12":[96],"post-learning":[98],"this":[100],"agreement":[103],"with":[104],"studies":[105],"employing":[106],"inhibitors":[107],"global":[109],"translation.":[110],"Functional":[111],"classification":[112],"memory-associated":[115,158],"revealed":[117],"majority":[120],"contributed":[124],"either":[125],"cellular":[127,130],"structure":[128],"or":[129],"metabolism.":[131],"For":[132],"example,":[133],"actins,":[134],"tubulins":[135],"intermediate":[137],"filament":[138],"proteins,":[139],"core":[140],"three":[144],"major":[145],"cytoskeletal":[146],"components,":[147],"dynamically":[149],"suggest":[154],"role":[156,219],"reorganization.":[160],"Increased":[161],"proteasome-mediated":[162],"degradation":[164],"was":[165],"evident":[166],"early":[169],"post-training":[170],"period":[171],"including":[172,204],"down-regulation":[174],"phosphoprotein":[176],"enriched":[177],"astrocytes":[179],"15":[180],"kDa,":[181],"inhibitor":[184],"extracellular":[186],"signal-regulated":[187],"kinase":[188],"signaling.":[189],"Some":[190],"most":[193],"substantial":[194],"observed":[199],"for":[200],"secreted":[201],"carrier":[202],"transthyretin":[205],"serum":[207],"albumin":[208],"6-12":[210],"post-learning,":[212],"regulations":[213,247],"could":[215],"serve":[216],"an":[217],"important":[218],"supply":[223],"retinoic":[225],"acid":[226],"thyroid":[228],"hormone,":[229],"plasticity-promoting":[232],"signals":[233],"adult":[236],"brain.":[237],"Together":[238],"these":[239],"observations":[240],"provide":[241],"further":[242],"insight":[243],"into":[244],"level":[246],"occurring":[248],"hippocampus":[251],"during":[252]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}
