{"id":"https://openalex.org/W2051929239","doi":"https://doi.org/10.1016/j.maturitas.2006.04.017","title":"Hormonal imbalance in two types of endometrial cancer and genetic polymorphism of steroidogenic enzymes","display_name":"Hormonal imbalance in two types of endometrial cancer and genetic polymorphism of steroidogenic enzymes","publication_year":2006,"publication_date":"2006-06-01","ids":{"openalex":"https://openalex.org/W2051929239","doi":"https://doi.org/10.1016/j.maturitas.2006.04.017","mag":"2051929239","pmid":"https://pubmed.ncbi.nlm.nih.gov/16730930"},"language":"en","primary_location":{"id":"doi:10.1016/j.maturitas.2006.04.017","doi":"https://doi.org/10.1016/j.maturitas.2006.04.017","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.maturitas.2006.04.017","pdf_url":null,"source":{"id":"https://openalex.org/S127492747","display_name":"Maturitas","issn_l":"0378-5122","issn":["0378-5122","1873-4111"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Maturitas","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021151348","display_name":"Lev M. Berstein","orcid":"https://orcid.org/0000-0002-5112-3372","observed_orcids":["https://orcid.org/0000-0002-5112-3372"]},"institutions":[{"id":"https://openalex.org/I4210116304","display_name":"Institute of Oncology NN Petrov","ror":"https://ror.org/01mfpjp46","country_code":"RU","type":"healthcare","lineage":["https://openalex.org/I4210116304","https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":true,"raw_author_name":"Lev Berstein","raw_affiliation_strings":["Lab. Oncoendocrinology, N.N. Petrov Research Institute of Oncology, Pesochny, St. Petersburg 197758, Russia. levmb@endocrin.spb.ru","Lab. Oncoendocrinology, N.N. Petrov Research Institute of Oncology, Pesochny, St. Petersburg 197758, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab. Oncoendocrinology, N.N. Petrov Research Institute of Oncology, Pesochny, St. Petersburg 197758, Russia. levmb@endocrin.spb.ru","institution_ids":["https://openalex.org/I4210116304"]},{"raw_affiliation_string":"Lab. Oncoendocrinology, N.N. Petrov Research Institute of Oncology, Pesochny, St. Petersburg 197758, Russia","institution_ids":["https://openalex.org/I4210116304"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008101109","display_name":"T. S. Zimarina","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210116304","display_name":"Institute of Oncology NN Petrov","ror":"https://ror.org/01mfpjp46","country_code":"RU","type":"healthcare","lineage":["https://openalex.org/I4210116304","https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Tatjana Zimarina","raw_affiliation_strings":["Lab. Oncoendocrinology, N.N. Petrov Research Institute of Oncology, Pesochny, St. Petersburg 197758, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab. Oncoendocrinology, N.N. Petrov Research Institute of Oncology, Pesochny, St. Petersburg 197758, Russia","institution_ids":["https://openalex.org/I4210116304"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112420652","display_name":"Evgeny Imyanitov","orcid":"https://orcid.org/0000-0003-4529-7891","observed_orcids":["https://orcid.org/0000-0003-4529-7891"]},"institutions":[{"id":"https://openalex.org/I4210116304","display_name":"Institute of Oncology NN Petrov","ror":"https://ror.org/01mfpjp46","country_code":"RU","type":"healthcare","lineage":["https://openalex.org/I4210116304","https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Evgeny Imyanitov","raw_affiliation_strings":["Lab. Oncoendocrinology, N.N. Petrov Research Institute of Oncology, Pesochny, St. Petersburg 197758, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab. Oncoendocrinology, N.N. Petrov Research Institute of Oncology, Pesochny, St. Petersburg 197758, Russia","institution_ids":["https://openalex.org/I4210116304"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073906486","display_name":"\u0410 \u042e \u041a\u043e\u0432\u0430\u043b\u0435\u0432\u0441\u043a\u0438\u0439","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210116304","display_name":"Institute of Oncology NN Petrov","ror":"https://ror.org/01mfpjp46","country_code":"RU","type":"healthcare","lineage":["https://openalex.org/I4210116304","https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Anatolij Kovalevskij","raw_affiliation_strings":["Lab. Oncoendocrinology, N.N. Petrov Research Institute of Oncology, Pesochny, St. Petersburg 197758, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab. Oncoendocrinology, N.N. Petrov Research Institute of Oncology, Pesochny, St. Petersburg 197758, Russia","institution_ids":["https://openalex.org/I4210116304"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113610558","display_name":"Sergei Maximov","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210116304","display_name":"Institute of Oncology NN Petrov","ror":"https://ror.org/01mfpjp46","country_code":"RU","type":"healthcare","lineage":["https://openalex.org/I4210116304","https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Sergei Maximov","raw_affiliation_strings":["Lab. Oncoendocrinology, N.N. Petrov Research Institute of Oncology, Pesochny, St. Petersburg 197758, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab. Oncoendocrinology, N.N. Petrov Research Institute of Oncology, Pesochny, St. Petersburg 197758, Russia","institution_ids":["https://openalex.org/I4210116304"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060814256","display_name":"Pascal Pujol","orcid":"https://orcid.org/0000-0001-8315-4715","observed_orcids":["https://orcid.org/0000-0001-8315-4715"]},"institutions":[{"id":"https://openalex.org/I4210147545","display_name":"H\u00f4pital Arnaud de Villeneuve","ror":"https://ror.org/04m6sq715","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210093292","https://openalex.org/I4210147545"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Pascal Pujol","raw_affiliation_strings":["University Hospital Arnaud de Villeneuve, Montpellier, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Hospital Arnaud de Villeneuve, Montpellier, France","institution_ids":["https://openalex.org/I4210147545"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029258716","display_name":"J.H.H. Thijssen","orcid":"https://orcid.org/0000-0001-9898-7939","observed_orcids":["https://orcid.org/0000-0001-9898-7939"]},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Jos Thijssen","raw_affiliation_strings":["University Medical Center, Utrecht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Medical Center, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I3018483916"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5021151348"],"corresponding_institution_ids":["https://openalex.org/I4210116304"],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":0.5276,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.57760583,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"54","issue":"4","first_page":"352","last_page":"355"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.43209999799728394,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.43209999799728394,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10668","display_name":"Endometrial and Cervical Cancer Treatments","score":0.2329999953508377,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.17020000517368317,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/endometrial-cancer","display_name":"endometrial cancer","score":0.9990000128746033},{"id":"https://openalex.org/keywords/type-i-endometrial-cancer","display_name":"type I endometrial cancer","score":0.8029999732971191},{"id":"https://openalex.org/keywords/type-ii-endometrial-cancer","display_name":"type II endometrial cancer","score":0.9959999918937683},{"id":"https://openalex.org/keywords/cyp17","display_name":"CYP17","score":0.8960000276565552},{"id":"https://openalex.org/keywords/cyp1b1","display_name":"CYP1B1","score":0.9430000185966492},{"id":"https://openalex.org/keywords/catechol-o-methyltransferase","display_name":"catechol-O-methyltransferase","score":0.949999988079071},{"id":"https://openalex.org/keywords/catechol-estrogens","display_name":"catechol estrogens","score":0.6200000047683716},{"id":"https://openalex.org/keywords/estrogen-metabolism","display_name":"estrogen metabolism","score":0.8989999890327454},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.7570000290870667}],"concepts":[{"id":"https://openalex.org/C2777088508","wikidata":"https://www.wikidata.org/wiki/Q944777","display_name":"Endometrial cancer","level":3,"score":0.7281773090362549},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.7258915901184082},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.60662841796875},{"id":"https://openalex.org/C31467283","wikidata":"https://www.wikidata.org/wiki/Q912147","display_name":"Genotyping","level":4,"score":0.575300931930542},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.5276721119880676},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5224253535270691},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5124748349189758},{"id":"https://openalex.org/C2776166826","wikidata":"https://www.wikidata.org/wiki/Q415287","display_name":"Aromatase","level":4,"score":0.4246540665626526},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.3743059039115906},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.35646045207977295},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2740393579006195},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.25770673155784607},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.25329098105430603}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001141","descriptor_name":"Aromatase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001189","descriptor_name":"Aryl Hydrocarbon Hydroxylases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002394","descriptor_name":"Catechol O-Methyltransferase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011110","descriptor_name":"Polymorphism, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012739","descriptor_name":"Gonadal Steroid Hormones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013254","descriptor_name":"Steroid 17-alpha-Hydroxylase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016889","descriptor_name":"Endometrial Neoplasms","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D016889","descriptor_name":"Endometrial Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D065633","descriptor_name":"Cytochrome P-450 CYP1B1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.maturitas.2006.04.017","doi":"https://doi.org/10.1016/j.maturitas.2006.04.017","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.maturitas.2006.04.017","pdf_url":null,"source":{"id":"https://openalex.org/S127492747","display_name":"Maturitas","issn_l":"0378-5122","issn":["0378-5122","1873-4111"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Maturitas","raw_type":"journal-article"},{"id":"pmid:16730930","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16730930","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Maturitas","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W640861656","https://openalex.org/W1927362057","https://openalex.org/W1979796130","https://openalex.org/W2025766286","https://openalex.org/W2044869180","https://openalex.org/W2049759619","https://openalex.org/W2051036355","https://openalex.org/W2072900847","https://openalex.org/W2092552784","https://openalex.org/W2107410297","https://openalex.org/W2127743211","https://openalex.org/W2135247123","https://openalex.org/W2144358598","https://openalex.org/W2145034430","https://openalex.org/W2163168485","https://openalex.org/W2169876423","https://openalex.org/W2516689327","https://openalex.org/W4285719527","https://openalex.org/W6640425905","https://openalex.org/W6726445568"],"related_works":["https://openalex.org/W2169876423","https://openalex.org/W2407893103","https://openalex.org/W2412129714","https://openalex.org/W2092552784","https://openalex.org/W2049759619","https://openalex.org/W2392838142","https://openalex.org/W2471130855","https://openalex.org/W2407634868","https://openalex.org/W2135247123","https://openalex.org/W2051036355"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}