{"id":"https://openalex.org/W2051923830","doi":"https://doi.org/10.1128/jvi.00596-09","title":"A Point Mutation, E95D, in the Mumps Virus V Protein Disengages STAT3 Targeting from STAT1 Targeting","display_name":"A Point Mutation, E95D, in the Mumps Virus V Protein Disengages STAT3 Targeting from STAT1 Targeting","publication_year":2009,"publication_date":"2009-04-23","ids":{"openalex":"https://openalex.org/W2051923830","doi":"https://doi.org/10.1128/jvi.00596-09","mag":"2051923830","pmid":"https://pubmed.ncbi.nlm.nih.gov/19386700","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2698558"},"language":"en","primary_location":{"id":"doi:10.1128/jvi.00596-09","doi":"https://doi.org/10.1128/jvi.00596-09","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.00596-09","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2698558/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029389562","display_name":"Mamta Puri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mamta Puri","raw_affiliation_strings":["Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, Evanston, Illinois 60208-3500","Department of Biochemistry, Molecular Biology and Cell Biology , Northwestern University, Evanston, Illinois 60208-3500, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, Evanston, Illinois 60208-3500","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"Department of Biochemistry, Molecular Biology and Cell Biology , Northwestern University, Evanston, Illinois 60208-3500, USA","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047359982","display_name":"Ken Lemon","orcid":"https://orcid.org/0000-0001-9844-1573","observed_orcids":["https://orcid.org/0000-0001-9844-1573"]},"institutions":[{"id":"https://openalex.org/I126231945","display_name":"Queen's University Belfast","ror":"https://ror.org/00hswnk62","country_code":"GB","type":"education","lineage":["https://openalex.org/I126231945"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ken Lemon","raw_affiliation_strings":["School of Biomedical Sciences, The Queen's University of Belfast, 97 Lisburn Road, Belfast, United Kingdom BT9 7BL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biomedical Sciences, The Queen's University of Belfast, 97 Lisburn Road, Belfast, United Kingdom BT9 7BL","institution_ids":["https://openalex.org/I126231945"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037052996","display_name":"William Paul Duprex","orcid":"https://orcid.org/0000-0003-1716-6376","observed_orcids":["https://orcid.org/0000-0003-1716-6376"]},"institutions":[{"id":"https://openalex.org/I126231945","display_name":"Queen's University Belfast","ror":"https://ror.org/00hswnk62","country_code":"GB","type":"education","lineage":["https://openalex.org/I126231945"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"W. Paul Duprex","raw_affiliation_strings":["School of Biomedical Sciences, The Queen's University of Belfast, 97 Lisburn Road, Belfast, United Kingdom BT9 7BL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biomedical Sciences, The Queen's University of Belfast, 97 Lisburn Road, Belfast, United Kingdom BT9 7BL","institution_ids":["https://openalex.org/I126231945"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113862358","display_name":"Bertus K. Rima","orcid":"https://orcid.org/0000-0002-1427-4120","observed_orcids":["https://orcid.org/0000-0002-1427-4120"]},"institutions":[{"id":"https://openalex.org/I126231945","display_name":"Queen's University Belfast","ror":"https://ror.org/00hswnk62","country_code":"GB","type":"education","lineage":["https://openalex.org/I126231945"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Bertus K. Rima","raw_affiliation_strings":["School of Biomedical Sciences, The Queen's University of Belfast, 97 Lisburn Road, Belfast, United Kingdom BT9 7BL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biomedical Sciences, The Queen's University of Belfast, 97 Lisburn Road, Belfast, United Kingdom BT9 7BL","institution_ids":["https://openalex.org/I126231945"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009824810","display_name":"Curt M. Horvath","orcid":"https://orcid.org/0000-0003-2449-225X","observed_orcids":["https://orcid.org/0000-0003-2449-225X"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Curt M. Horvath","raw_affiliation_strings":["Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, Evanston, Illinois 60208-3500","Medicine, Hematology Oncology Division"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, Evanston, Illinois 60208-3500","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"Medicine, Hematology Oncology Division","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5009824810"],"corresponding_institution_ids":["https://openalex.org/I111979921"],"apc_list":null,"apc_paid":null,"fwci":1.0921,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.78017363,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"83","issue":"13","first_page":"6347","last_page":"6356"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11135","display_name":"Virology and Viral Diseases","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11135","display_name":"Virology and Viral Diseases","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.006000000052154064,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11503","display_name":"Cytokine Signaling Pathways and Interactions","score":0.004900000058114529,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mumps-virus","display_name":"mumps virus","score":0.9890000224113464},{"id":"https://openalex.org/keywords/v-protein","display_name":"V protein","score":0.9390000104904175},{"id":"https://openalex.org/keywords/stat3","display_name":"STAT3","score":0.7720000147819519},{"id":"https://openalex.org/keywords/stat1","display_name":"STAT1","score":0.9940000176429749},{"id":"https://openalex.org/keywords/point-mutations","display_name":"point mutations","score":0.9049999713897705},{"id":"https://openalex.org/keywords/ubiquitin-ligase","display_name":"ubiquitin ligase","score":0.8399999737739563},{"id":"https://openalex.org/keywords/proteasomal-degradation","display_name":"proteasomal degradation","score":0.828000009059906},{"id":"https://openalex.org/keywords/interferon-signaling","display_name":"interferon signaling","score":0.6389999985694885},{"id":"https://openalex.org/keywords/viral-protein-protein-interaction","display_name":"viral protein-protein interaction","score":0.4819999933242798},{"id":"https://openalex.org/keywords/cell-death","display_name":"cell death","score":0.8220000267028809},{"id":"https://openalex.org/keywords/rubulavirus","display_name":"Rubulavirus","score":0.6869999766349792},{"id":"https://openalex.org/keywords/paramyxovirus","display_name":"paramyxovirus","score":0.7200000286102295}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8267579674720764},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.6429795026779175},{"id":"https://openalex.org/C2778923194","wikidata":"https://www.wikidata.org/wiki/Q14912019","display_name":"STAT3","level":3,"score":0.6244684457778931},{"id":"https://openalex.org/C176944494","wikidata":"https://www.wikidata.org/wiki/Q1415380","display_name":"Point mutation","level":4,"score":0.6147795915603638},{"id":"https://openalex.org/C2777003663","wikidata":"https://www.wikidata.org/wiki/Q14912030","display_name":"STAT1","level":3,"score":0.5481522083282471},{"id":"https://openalex.org/C2778538096","wikidata":"https://www.wikidata.org/wiki/Q29004679","display_name":"Mumps virus","level":3,"score":0.5205541849136353},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.46685081720352173},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.39151477813720703},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3338942527770996},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.330853670835495},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.28775298595428467},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.26688238978385925},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2279777228832245},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.15688538551330566},{"id":"https://openalex.org/C2776178377","wikidata":"https://www.wikidata.org/wiki/Q188269","display_name":"Interferon","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002522","descriptor_name":"Chlorocebus aethiops","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009107","descriptor_name":"Mumps","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D009109","descriptor_name":"Mumps virus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009109","descriptor_name":"Mumps virus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014709","descriptor_name":"Vero Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014764","descriptor_name":"Viral Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014764","descriptor_name":"Viral Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016297","descriptor_name":"Mutagenesis, Site-Directed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017354","descriptor_name":"Point Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019943","descriptor_name":"Amino Acid Substitution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050794","descriptor_name":"STAT1 Transcription Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D050796","descriptor_name":"STAT3 Transcription Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1128/jvi.00596-09","doi":"https://doi.org/10.1128/jvi.00596-09","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.00596-09","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},{"id":"pmid:19386700","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19386700","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of virology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2698558","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2698558/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2698558","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2698558/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1181685105","display_name":"Helicase Regulation of dsRNA Signaling and Innate Antiviral Immune Responses","funder_award_id":"R01AI073919","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320309432","display_name":"F. Hoffmann-La Roche","ror":"https://ror.org/00by1q217"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":62,"referenced_works":["https://openalex.org/W48152255","https://openalex.org/W344789099","https://openalex.org/W1743711678","https://openalex.org/W1779691448","https://openalex.org/W1810300540","https://openalex.org/W1977079961","https://openalex.org/W1983166456","https://openalex.org/W1983989619","https://openalex.org/W1993618642","https://openalex.org/W1994203138","https://openalex.org/W1995997868","https://openalex.org/W2004995275","https://openalex.org/W2007320083","https://openalex.org/W2012588545","https://openalex.org/W2030819935","https://openalex.org/W2032674547","https://openalex.org/W2034134903","https://openalex.org/W2042218061","https://openalex.org/W2043188148","https://openalex.org/W2055394691","https://openalex.org/W2058584950","https://openalex.org/W2062924985","https://openalex.org/W2066647113","https://openalex.org/W2073684796","https://openalex.org/W2074356752","https://openalex.org/W2081098333","https://openalex.org/W2082167075","https://openalex.org/W2083162753","https://openalex.org/W2083802827","https://openalex.org/W2093953283","https://openalex.org/W2100878564","https://openalex.org/W2103422355","https://openalex.org/W2104707719","https://openalex.org/W2108230641","https://openalex.org/W2109581133","https://openalex.org/W2115110988","https://openalex.org/W2117819885","https://openalex.org/W2128200051","https://openalex.org/W2132148594","https://openalex.org/W2132975022","https://openalex.org/W2136690547","https://openalex.org/W2137077743","https://openalex.org/W2137648328","https://openalex.org/W2139405922","https://openalex.org/W2142572392","https://openalex.org/W2143261659","https://openalex.org/W2148425212","https://openalex.org/W2149541458","https://openalex.org/W2155005693","https://openalex.org/W2155530747","https://openalex.org/W2156449667","https://openalex.org/W2157111385","https://openalex.org/W2159370470","https://openalex.org/W2164891125","https://openalex.org/W2165849880","https://openalex.org/W2169420807","https://openalex.org/W2171984409","https://openalex.org/W2251917818","https://openalex.org/W2419090891","https://openalex.org/W2783142245","https://openalex.org/W4249713142","https://openalex.org/W4250386923"],"related_works":["https://openalex.org/W2985347785","https://openalex.org/W2165849880","https://openalex.org/W2127228010","https://openalex.org/W2171984409","https://openalex.org/W1993618642","https://openalex.org/W7095705065","https://openalex.org/W2007320083","https://openalex.org/W2109581133","https://openalex.org/W2132148594","https://openalex.org/W7100396198"],"abstract_inverted_index":{"Mumps":[0],"virus,":[1],"like":[2],"other":[3],"paramyxoviruses":[4],"in":[5,54,76,84,120,128,144,163],"the":[6,25,42,77,90,98,102,105,117,140,145],"Rubulavirus":[7],"genus,":[8],"encodes":[9],"a":[10,16,71,149,167],"V":[11,39,50,80,106,124],"protein":[12,51,107],"that":[13,70,97],"can":[14],"assemble":[15],"ubiquitin":[17,62],"ligase":[18],"complex":[19],"from":[20],"cellular":[21,28,152],"components,":[22],"leading":[23],"to":[24,57,92,108,133,155],"destruction":[26],"of":[27,33,104,136,148,151],"signal":[29],"transducer":[30],"and":[31,64,123,159],"activator":[32],"transcription":[34],"(STAT)":[35],"proteins.":[36],"While":[37],"many":[38],"proteins":[40,125],"target":[41,59,93],"interferon-activated":[43],"STAT1":[44],"or":[45],"STAT2":[46],"protein,":[47,81],"mumps":[48,78,114,157],"virus":[49,79,115,142,158],"is":[52],"unique":[53],"its":[55,121],"ability":[56,91,103],"also":[58],"STAT3":[60,86],"for":[61],"modification":[63],"proteasome-mediated":[65],"degradation.":[66],"Here":[67],"we":[68],"report":[69],"single":[72],"amino":[73],"acid":[74],"substitution":[75],"E95D,":[82],"results":[83,143],"defective":[85],"targeting":[87,135],"while":[88],"maintaining":[89],"STAT1.":[94],"Results":[95],"indicate":[96],"E95D":[99,118],"mutation":[100,119],"disrupts":[101],"associate":[109],"with":[110,139],"STAT3.":[111,137],"A":[112],"recombinant":[113,141],"carrying":[116],"P":[122],"replicates":[126],"normally":[127],"cultured":[129],"cells":[130],"but":[131],"fails":[132],"induce":[134],"Infection":[138],"differential":[146],"regulation":[147],"number":[150],"genes":[153],"compared":[154],"wild-type":[156],"increases":[160],"cell":[161],"death":[162],"infected":[164],"cells,":[165],"producing":[166],"large-plaque":[168],"phenotype.":[169]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}