{"id":"https://openalex.org/W2051637260","doi":"https://doi.org/10.1016/s0041-0101(02)00115-0","title":"Tetrodotoxin levels of the rough-skin newt, Taricha granulosa, increase in long-term captivity","display_name":"Tetrodotoxin levels of the rough-skin newt, Taricha granulosa, increase in long-term captivity","publication_year":2002,"publication_date":"2002-08-01","ids":{"openalex":"https://openalex.org/W2051637260","doi":"https://doi.org/10.1016/s0041-0101(02)00115-0","mag":"2051637260","pmid":"https://pubmed.ncbi.nlm.nih.gov/12165318"},"language":"en","primary_location":{"id":"doi:10.1016/s0041-0101(02)00115-0","doi":"https://doi.org/10.1016/s0041-0101(02)00115-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0041-0101(02)00115-0","pdf_url":null,"source":{"id":"https://openalex.org/S42803210","display_name":"Toxicon","issn_l":"0041-0101","issn":["0041-0101","1879-3150"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicon","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073237109","display_name":"Charles T. Hanifin","orcid":"https://orcid.org/0000-0003-4930-7698","observed_orcids":["https://orcid.org/0000-0003-4930-7698"]},"institutions":[{"id":"https://openalex.org/I121980950","display_name":"Utah State University","ror":"https://ror.org/00h6set76","country_code":"US","type":"education","lineage":["https://openalex.org/I121980950"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Charles T. Hanifin","raw_affiliation_strings":["Department of Biology, Utah State University, Logan, UT 84322-5305, USA. chanifin@biology.usu.edu","Department of Biology, Utah State University, Logan, UT 84322-5305, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Utah State University, Logan, UT 84322-5305, USA. chanifin@biology.usu.edu","institution_ids":["https://openalex.org/I121980950"]},{"raw_affiliation_string":"Department of Biology, Utah State University, Logan, UT 84322-5305, USA","institution_ids":["https://openalex.org/I121980950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102866853","display_name":"Edmund D. Brodie","orcid":"https://orcid.org/0000-0002-5739-4747","observed_orcids":["https://orcid.org/0000-0002-5739-4747"]},"institutions":[{"id":"https://openalex.org/I121980950","display_name":"Utah State University","ror":"https://ror.org/00h6set76","country_code":"US","type":"education","lineage":["https://openalex.org/I121980950"]},{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Edmund D. Brodie","raw_affiliation_strings":["Department of Biology, Indiana University, Bloomington, IN 47405-3700, USA","Department of Biology, Utah State University, Logan, UT 84322-5305, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Indiana University, Bloomington, IN 47405-3700, USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"raw_affiliation_string":"Department of Biology, Utah State University, Logan, UT 84322-5305, USA","institution_ids":["https://openalex.org/I121980950"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102866853","display_name":"Edmund D. Brodie","orcid":"https://orcid.org/0000-0002-5739-4747","observed_orcids":["https://orcid.org/0000-0002-5739-4747"]},"institutions":[{"id":"https://openalex.org/I121980950","display_name":"Utah State University","ror":"https://ror.org/00h6set76","country_code":"US","type":"education","lineage":["https://openalex.org/I121980950"]},{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Edmund D. Brodie","raw_affiliation_strings":["Department of Biology, Indiana University, Bloomington, IN 47405-3700, USA","Department of Biology, Utah State University, Logan, UT 84322-5305, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Indiana University, Bloomington, IN 47405-3700, USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"raw_affiliation_string":"Department of Biology, Utah State University, Logan, UT 84322-5305, USA","institution_ids":["https://openalex.org/I121980950"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5073237109"],"corresponding_institution_ids":["https://openalex.org/I121980950"],"apc_list":{"value":3340,"currency":"USD","value_usd":3340},"apc_paid":null,"fwci":1.9449,"has_fulltext":false,"cited_by_count":109,"citation_normalized_percentile":{"value":0.85519388,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"40","issue":"8","first_page":"1149","last_page":"1153"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11353","display_name":"Venomous Animal Envenomation and Studies","score":0.44749999046325684,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11353","display_name":"Venomous Animal Envenomation and Studies","score":0.44749999046325684,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10332","display_name":"Amphibian and Reptile Biology","score":0.4203999936580658,"subfield":{"id":"https://openalex.org/subfields/2306","display_name":"Global and Planetary Change"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11985","display_name":"Marine Toxins and Detection Methods","score":0.07039999961853027,"subfield":{"id":"https://openalex.org/subfields/2304","display_name":"Environmental Chemistry"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tetrodotoxin","display_name":"tetrodotoxin","score":1.0},{"id":"https://openalex.org/keywords/taricha-granulosa","display_name":"Taricha granulosa","score":0.9950000047683716},{"id":"https://openalex.org/keywords/captive-husbandry","display_name":"captive husbandry","score":0.7440000176429749},{"id":"https://openalex.org/keywords/intrapopulation-variation","display_name":"intrapopulation variation","score":0.7950000166893005},{"id":"https://openalex.org/keywords/non-lethal-sampling","display_name":"non-lethal sampling","score":0.8450000286102295}],"concepts":[{"id":"https://openalex.org/C2776741303","wikidata":"https://www.wikidata.org/wiki/Q379842","display_name":"Tetrodotoxin","level":2,"score":0.8280095458030701},{"id":"https://openalex.org/C2776787076","wikidata":"https://www.wikidata.org/wiki/Q2920296","display_name":"Captivity","level":2,"score":0.8126212954521179},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.799280047416687},{"id":"https://openalex.org/C2781465898","wikidata":"https://www.wikidata.org/wiki/Q10908","display_name":"Amphibian","level":2,"score":0.6692702174186707},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.6064203977584839},{"id":"https://openalex.org/C90856448","wikidata":"https://www.wikidata.org/wiki/Q431","display_name":"Zoology","level":1,"score":0.5927768349647522},{"id":"https://openalex.org/C2780214594","wikidata":"https://www.wikidata.org/wiki/Q28208678","display_name":"Caudata","level":2,"score":0.4826231896877289},{"id":"https://openalex.org/C2780358027","wikidata":"https://www.wikidata.org/wiki/Q407752","display_name":"Neurotoxin","level":2,"score":0.4520069658756256},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.40406808257102966},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2635655403137207},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004777","descriptor_name":"Environment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012455","descriptor_name":"Salamandridae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012727","descriptor_name":"Sex Characteristics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013050","descriptor_name":"Spectrometry, Fluorescence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013237","descriptor_name":"Stereoisomerism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013779","descriptor_name":"Tetrodotoxin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013779","descriptor_name":"Tetrodotoxin","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D013779","descriptor_name":"Tetrodotoxin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0041-0101(02)00115-0","doi":"https://doi.org/10.1016/s0041-0101(02)00115-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0041-0101(02)00115-0","pdf_url":null,"source":{"id":"https://openalex.org/S42803210","display_name":"Toxicon","issn_l":"0041-0101","issn":["0041-0101","1879-3150"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicon","raw_type":"journal-article"},{"id":"pmid:12165318","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12165318","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicon : official journal of the International Society on Toxinology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320309198","display_name":"Utah State University","ror":"https://ror.org/00h6set76"},{"id":"https://openalex.org/F4320311401","display_name":"Oregon State University","ror":"https://ror.org/00ysfqy60"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1504794559","https://openalex.org/W1974573249","https://openalex.org/W1982249923","https://openalex.org/W2004588610","https://openalex.org/W2007453747","https://openalex.org/W2009929723","https://openalex.org/W2015313823","https://openalex.org/W2015922110","https://openalex.org/W2025810556","https://openalex.org/W2053567915","https://openalex.org/W2059105596","https://openalex.org/W2089500621","https://openalex.org/W2090804497","https://openalex.org/W2106801310","https://openalex.org/W2179676624","https://openalex.org/W2183570127","https://openalex.org/W2286959103","https://openalex.org/W2314261456","https://openalex.org/W2317098120","https://openalex.org/W2322778052","https://openalex.org/W2333938571","https://openalex.org/W2478137956"],"related_works":["https://openalex.org/W2146497665","https://openalex.org/W4223619041","https://openalex.org/W2099783348","https://openalex.org/W2000110768","https://openalex.org/W2109753561","https://openalex.org/W172321755","https://openalex.org/W4200423423","https://openalex.org/W318617244","https://openalex.org/W2960647464","https://openalex.org/W3157998920"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":7}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}