{"id":"https://openalex.org/W2051576341","doi":"https://doi.org/10.1016/s1074-7613(00)80291-5","title":"Critical Roles for the Bcl-3 Oncoprotein in T Cell\u2013Mediated Immunity, Splenic Microarchitecture, and Germinal Center Reactions","display_name":"Critical Roles for the Bcl-3 Oncoprotein in T Cell\u2013Mediated Immunity, Splenic Microarchitecture, and Germinal Center Reactions","publication_year":1997,"publication_date":"1997-04-01","ids":{"openalex":"https://openalex.org/W2051576341","doi":"https://doi.org/10.1016/s1074-7613(00)80291-5","mag":"2051576341","pmid":"https://pubmed.ncbi.nlm.nih.gov/9133427"},"language":"en","primary_location":{"id":"doi:10.1016/s1074-7613(00)80291-5","doi":"https://doi.org/10.1016/s1074-7613(00)80291-5","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1074-7613(00)80291-5","pdf_url":"http://www.cell.com/article/S1074761300802915/pdf","source":{"id":"https://openalex.org/S199671312","display_name":"Immunity","issn_l":"1074-7613","issn":["1074-7613","1097-4180"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunity","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S1074761300802915/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017597678","display_name":"Guido Franzoso","orcid":"https://orcid.org/0000-0002-0778-988X","observed_orcids":["https://orcid.org/0000-0002-0778-988X"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guido Franzoso","raw_affiliation_strings":["Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland-20892, USA","Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland-20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534"]},{"raw_affiliation_string":"Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, USA","institution_ids":["https://openalex.org/I4210134534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005595410","display_name":"Louise M. Carlson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Louise Carlson","raw_affiliation_strings":["Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, USA","institution_ids":["https://openalex.org/I4210134534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077989864","display_name":"Tanya Scharton\u2010Kersten","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tanya Scharton-Kersten","raw_affiliation_strings":["Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, USA","institution_ids":["https://openalex.org/I4210134534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021909363","display_name":"Elizabeth W. Shores","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elizabeth W Shores","raw_affiliation_strings":["Division of Hematologic Products, Center for Biological Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematologic Products, Center for Biological Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA","institution_ids":["https://openalex.org/I1320320070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007883445","display_name":"Suzanne L. Epstein","orcid":"https://orcid.org/0000-0002-6311-6890","observed_orcids":["https://orcid.org/0000-0002-6311-6890"]},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Suzanne Epstein","raw_affiliation_strings":["Division of Cellular and Gene Therapies, Center for Biological Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cellular and Gene Therapies, Center for Biological Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA","institution_ids":["https://openalex.org/I1320320070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087294420","display_name":"Alexander Grinberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexander Grinberg","raw_affiliation_strings":["Laboratory of Molecular Genetics, National Institute of Child Health, and Human Development, National Institutes of Health, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Genetics, National Institute of Child Health, and Human Development, National Institutes of Health, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023813482","display_name":"Tom Tran","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tom Tran","raw_affiliation_strings":["Division of Hematologic Products, Center for Biological Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematologic Products, Center for Biological Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA","institution_ids":["https://openalex.org/I1320320070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058555394","display_name":"Emily B. Shacter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emily Shacter","raw_affiliation_strings":["Division of Hematologic Products, Center for Biological Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematologic Products, Center for Biological Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA","institution_ids":["https://openalex.org/I1320320070"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053006729","display_name":"Antonio Leonardi","orcid":"https://orcid.org/0000-0001-8636-9623","observed_orcids":["https://orcid.org/0000-0001-8636-9623"]},"institutions":[{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Antonio Leonardi","raw_affiliation_strings":["Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, USA","institution_ids":["https://openalex.org/I4210134534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026882105","display_name":"Miriam R. Anver","orcid":"https://orcid.org/0000-0003-2665-8794","observed_orcids":["https://orcid.org/0000-0003-2665-8794"]},"institutions":[{"id":"https://openalex.org/I114662689","display_name":"Leidos (United States)","ror":"https://ror.org/012cvds63","country_code":"US","type":"company","lineage":["https://openalex.org/I114662689"]},{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I880747138","display_name":"Science Applications International Corporation (United States)","ror":"https://ror.org/00zv91802","country_code":"US","type":"company","lineage":["https://openalex.org/I880747138"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Miriam Anver","raw_affiliation_strings":["Pathology/Histotechnology Laboratory, Science Applications International Corporation, and National Cancer Institute, Frederick Cancer Research and Development Center, Frederick, Maryland 21702, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pathology/Histotechnology Laboratory, Science Applications International Corporation, and National Cancer Institute, Frederick Cancer Research and Development Center, Frederick, Maryland 21702, USA","institution_ids":["https://openalex.org/I114662689","https://openalex.org/I4210130649","https://openalex.org/I4210140884","https://openalex.org/I880747138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043853595","display_name":"Paul E. Love","orcid":"https://orcid.org/0000-0002-6682-7372","observed_orcids":["https://orcid.org/0000-0002-6682-7372"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul Love","raw_affiliation_strings":["Laboratory of Molecular Genetics, National Institute of Child Health, and Human Development, National Institutes of Health, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Genetics, National Institute of Child Health, and Human Development, National Institutes of Health, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016487212","display_name":"Alan Sher","orcid":"https://orcid.org/0000-0001-7053-2895","observed_orcids":["https://orcid.org/0000-0001-7053-2895"]},"institutions":[{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alan Sher","raw_affiliation_strings":["Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, USA","institution_ids":["https://openalex.org/I4210134534"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009843959","display_name":"Ulrich K. Siebenlist","orcid":"https://orcid.org/0000-0002-7424-7992","observed_orcids":["https://orcid.org/0000-0002-7424-7992"]},"institutions":[{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ulrich Siebenlist","raw_affiliation_strings":["Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, USA","institution_ids":["https://openalex.org/I4210134534"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5009843959"],"corresponding_institution_ids":["https://openalex.org/I4210134534"],"apc_list":{"value":10400,"currency":"USD","value_usd":10400},"apc_paid":null,"fwci":5.1194,"has_fulltext":false,"cited_by_count":175,"citation_normalized_percentile":{"value":0.95729515,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"6","issue":"4","first_page":"479","last_page":"490"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.6884999871253967,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.6884999871253967,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11591","display_name":"NF-\u03baB Signaling Pathways","score":0.295199990272522,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.0035000001080334187,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bcl-3","display_name":"Bcl-3","score":0.9990000128746033},{"id":"https://openalex.org/keywords/nf-kappab","display_name":"NF-\u03baB","score":0.7210000157356262},{"id":"https://openalex.org/keywords/t-cell-mediated-immunity","display_name":"T cell immunity","score":0.8130000233650208},{"id":"https://openalex.org/keywords/t-helper-1-response","display_name":"T helper 1 response","score":0.9269999861717224},{"id":"https://openalex.org/keywords/toxoplasma-gondii","display_name":"Toxoplasma gondii","score":0.9639999866485596},{"id":"https://openalex.org/keywords/germinal-center","display_name":"germinal center","score":0.7089999914169312},{"id":"https://openalex.org/keywords/t-cell-dependent-antibody-response","display_name":"T cell-dependent antibody response","score":0.8669999837875366},{"id":"https://openalex.org/keywords/influenza-virus","display_name":"influenza virus","score":0.8489999771118164},{"id":"https://openalex.org/keywords/chronic-lymphocytic-leukemia","display_name":"chronic lymphocytic leukemia","score":0.8679999709129333},{"id":"https://openalex.org/keywords/secondary-lymphoid-organs","display_name":"secondary lymphoid organs","score":0.8809999823570251}],"concepts":[{"id":"https://openalex.org/C96926380","wikidata":"https://www.wikidata.org/wiki/Q1737968","display_name":"Germinal center","level":4,"score":0.8958677053451538},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8095165491104126},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.6475611925125122},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4442492425441742},{"id":"https://openalex.org/C107598950","wikidata":"https://www.wikidata.org/wiki/Q259864","display_name":"Microarchitecture","level":2,"score":0.4142255485057831},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.39977478981018066},{"id":"https://openalex.org/C2778453870","wikidata":"https://www.wikidata.org/wiki/Q188930","display_name":"B cell","level":3,"score":0.2301121950149536},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.19694805145263672},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.14048829674720764},{"id":"https://openalex.org/C173608175","wikidata":"https://www.wikidata.org/wiki/Q232661","display_name":"Parallel computing","level":1,"score":0.06403452157974243},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000081242","descriptor_name":"B-Cell Lymphoma 3 Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000914","descriptor_name":"Antibodies, Viral","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004622","descriptor_name":"Embryo, Mammalian","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007111","descriptor_name":"Immunity, Cellular","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008815","descriptor_name":"Mice, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009980","descriptor_name":"Influenza A virus","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011518","descriptor_name":"Proto-Oncogene Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011518","descriptor_name":"Proto-Oncogene Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011519","descriptor_name":"Proto-Oncogenes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D014123","descriptor_name":"Toxoplasmosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014123","descriptor_name":"Toxoplasmosis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016175","descriptor_name":"B-Lymphocyte Subsets","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016175","descriptor_name":"B-Lymphocyte Subsets","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018858","descriptor_name":"Germinal Center","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D018858","descriptor_name":"Germinal Center","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s1074-7613(00)80291-5","doi":"https://doi.org/10.1016/s1074-7613(00)80291-5","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1074-7613(00)80291-5","pdf_url":"http://www.cell.com/article/S1074761300802915/pdf","source":{"id":"https://openalex.org/S199671312","display_name":"Immunity","issn_l":"1074-7613","issn":["1074-7613","1097-4180"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunity","raw_type":"journal-article"},{"id":"pmid:9133427","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9133427","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunity","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/s1074-7613(00)80291-5","doi":"https://doi.org/10.1016/s1074-7613(00)80291-5","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1074-7613(00)80291-5","pdf_url":"http://www.cell.com/article/S1074761300802915/pdf","source":{"id":"https://openalex.org/S199671312","display_name":"Immunity","issn_l":"1074-7613","issn":["1074-7613","1097-4180"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunity","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2051576341.pdf"},"referenced_works_count":70,"referenced_works":["https://openalex.org/W130851191","https://openalex.org/W188081618","https://openalex.org/W192057613","https://openalex.org/W204105501","https://openalex.org/W225292687","https://openalex.org/W1515875551","https://openalex.org/W1541965214","https://openalex.org/W1553499552","https://openalex.org/W1580262749","https://openalex.org/W1606782385","https://openalex.org/W1829577351","https://openalex.org/W1925420621","https://openalex.org/W1940201944","https://openalex.org/W1965503707","https://openalex.org/W1972044265","https://openalex.org/W1973173532","https://openalex.org/W1982062664","https://openalex.org/W1982554152","https://openalex.org/W1986006520","https://openalex.org/W1989997867","https://openalex.org/W1990572032","https://openalex.org/W1992815918","https://openalex.org/W1996134542","https://openalex.org/W2002674047","https://openalex.org/W2012116939","https://openalex.org/W2018718597","https://openalex.org/W2018794044","https://openalex.org/W2023999210","https://openalex.org/W2028744022","https://openalex.org/W2029875651","https://openalex.org/W2033810895","https://openalex.org/W2035616122","https://openalex.org/W2041354260","https://openalex.org/W2045793427","https://openalex.org/W2059257512","https://openalex.org/W2066730341","https://openalex.org/W2067567916","https://openalex.org/W2069080743","https://openalex.org/W2069173092","https://openalex.org/W2071551293","https://openalex.org/W2079235989","https://openalex.org/W2087653208","https://openalex.org/W2091094420","https://openalex.org/W2091695331","https://openalex.org/W2095408546","https://openalex.org/W2096589599","https://openalex.org/W2104383067","https://openalex.org/W2108473659","https://openalex.org/W2108526355","https://openalex.org/W2116487940","https://openalex.org/W2121655252","https://openalex.org/W2122559781","https://openalex.org/W2124829361","https://openalex.org/W2126524404","https://openalex.org/W2127125043","https://openalex.org/W2128508005","https://openalex.org/W2133140093","https://openalex.org/W2137268127","https://openalex.org/W2139587377","https://openalex.org/W2139605631","https://openalex.org/W2142541950","https://openalex.org/W2144152742","https://openalex.org/W2151892297","https://openalex.org/W2154790558","https://openalex.org/W2160644552","https://openalex.org/W2166781237","https://openalex.org/W2185814728","https://openalex.org/W2399901857","https://openalex.org/W4205403186","https://openalex.org/W4251633039"],"related_works":["https://openalex.org/W2145768405","https://openalex.org/W4313386161","https://openalex.org/W2147507133","https://openalex.org/W4313382850","https://openalex.org/W4385686012","https://openalex.org/W7097299393","https://openalex.org/W2094083392","https://openalex.org/W1501353843","https://openalex.org/W2304868333","https://openalex.org/W2333904918"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}