{"id":"https://openalex.org/W2051567027","doi":"https://doi.org/10.1038/nm.2173","title":"Serotonin regulates pancreatic beta cell mass during pregnancy","display_name":"Serotonin regulates pancreatic beta cell mass during pregnancy","publication_year":2010,"publication_date":"2010-06-27","ids":{"openalex":"https://openalex.org/W2051567027","doi":"https://doi.org/10.1038/nm.2173","mag":"2051567027","pmid":"https://pubmed.ncbi.nlm.nih.gov/20581837","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2921604"},"language":"en","primary_location":{"id":"doi:10.1038/nm.2173","doi":"https://doi.org/10.1038/nm.2173","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nm.2173","pdf_url":null,"source":{"id":"https://openalex.org/S203256638","display_name":"Nature Medicine","issn_l":"1078-8956","issn":["1078-8956","1546-170X","1744-7933"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2921604","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004697914","display_name":"Hail Kim","orcid":"https://orcid.org/0000-0002-6652-1349","observed_orcids":["https://orcid.org/0000-0002-6652-1349","https://orcid.org/0009-0009-1520-0308"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hail Kim","raw_affiliation_strings":["Diabetes Center, University of California-San Francisco, San Francisco, California, USA","Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diabetes Center, University of California-San Francisco, San Francisco, California, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028676713","display_name":"Yukiko Toyofuku","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I34077901","display_name":"Juntendo University","ror":"https://ror.org/01692sz90","country_code":"JP","type":"education","lineage":["https://openalex.org/I34077901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yukiko Toyofuku","raw_affiliation_strings":["Department of Medicine, Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039796888","display_name":"Francis C. Lynn","orcid":"https://orcid.org/0000-0001-9318-1063","observed_orcids":["https://orcid.org/0000-0001-9318-1063"]},"institutions":[{"id":"https://openalex.org/I141945490","display_name":"University of British Columbia","ror":"https://ror.org/03rmrcq20","country_code":"CA","type":"education","lineage":["https://openalex.org/I141945490"]},{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Francis C Lynn","raw_affiliation_strings":["Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, California, USA","Current address: Departments of Surgery and Cellular and Physiological Sciences, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.,","Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, California, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Current address: Departments of Surgery and Cellular and Physiological Sciences, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.,","institution_ids":["https://openalex.org/I141945490"]},{"raw_affiliation_string":"Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049228255","display_name":"Eric Chak","orcid":"https://orcid.org/0000-0001-6182-8002","observed_orcids":["https://orcid.org/0000-0001-6182-8002"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric Chak","raw_affiliation_strings":["Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, California, USA","Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, California, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037878079","display_name":"Toyoyoshi Uchida","orcid":"https://orcid.org/0000-0002-4301-2955","observed_orcids":["https://orcid.org/0000-0002-4301-2955"]},"institutions":[{"id":"https://openalex.org/I34077901","display_name":"Juntendo University","ror":"https://ror.org/01692sz90","country_code":"JP","type":"education","lineage":["https://openalex.org/I34077901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toyoyoshi Uchida","raw_affiliation_strings":["Department of Medicine, Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044985399","display_name":"Hiroki Mizukami","orcid":"https://orcid.org/0000-0003-2920-582X","observed_orcids":["https://orcid.org/0000-0003-2920-582X"]},"institutions":[{"id":"https://openalex.org/I146516829","display_name":"Hirosaki University","ror":"https://ror.org/02syg0q74","country_code":"JP","type":"education","lineage":["https://openalex.org/I146516829"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroki Mizukami","raw_affiliation_strings":["Department of Pathology and Molecular Medicine, Hirosaki University Graduate School of Medicine, Hirosaki, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Molecular Medicine, Hirosaki University Graduate School of Medicine, Hirosaki, Japan","institution_ids":["https://openalex.org/I146516829"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027831207","display_name":"Yoshio Fujitani","orcid":"https://orcid.org/0000-0003-0196-4736","observed_orcids":["https://orcid.org/0000-0003-0196-4736"]},"institutions":[{"id":"https://openalex.org/I34077901","display_name":"Juntendo University","ror":"https://ror.org/01692sz90","country_code":"JP","type":"education","lineage":["https://openalex.org/I34077901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshio Fujitani","raw_affiliation_strings":["Center for Therapeutic Innovations in Diabetes, Juntendo University Graduate School of Medicine, Tokyo, Japan","Department of Medicine, Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Therapeutic Innovations in Diabetes, Juntendo University Graduate School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]},{"raw_affiliation_string":"Department of Medicine, Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032317621","display_name":"Ryuzo Kawamori","orcid":"https://orcid.org/0000-0002-9686-9098","observed_orcids":["https://orcid.org/0000-0002-9686-9098"]},"institutions":[{"id":"https://openalex.org/I34077901","display_name":"Juntendo University","ror":"https://ror.org/01692sz90","country_code":"JP","type":"education","lineage":["https://openalex.org/I34077901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ryuzo Kawamori","raw_affiliation_strings":["Center for Beta Cell Biology and Regeneration, Juntendo University Graduate School of Medicine, Tokyo, Japan","Center for Therapeutic Innovations in Diabetes, Juntendo University Graduate School of Medicine, Tokyo, Japan","Department of Medicine, Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan","Sportology Center, Juntendo University Graduate School of Medicine, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Beta Cell Biology and Regeneration, Juntendo University Graduate School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]},{"raw_affiliation_string":"Center for Therapeutic Innovations in Diabetes, Juntendo University Graduate School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]},{"raw_affiliation_string":"Department of Medicine, Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]},{"raw_affiliation_string":"Sportology Center, Juntendo University Graduate School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077685039","display_name":"Takeshi Miyatsuka","orcid":"https://orcid.org/0000-0003-2618-3450","observed_orcids":["https://orcid.org/0000-0003-2618-3450"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Takeshi Miyatsuka","raw_affiliation_strings":["Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, California, USA","Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, California, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040599553","display_name":"Yasuhiro Kosaka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yasuhiro Kosaka","raw_affiliation_strings":["Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, California, USA","Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, California, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037861831","display_name":"Katherine Y. Yang","orcid":"https://orcid.org/0000-0003-3324-037X","observed_orcids":["https://orcid.org/0000-0003-3324-037X"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katherine Yang","raw_affiliation_strings":["Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, California, USA","Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, California, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037738974","display_name":"Gerard Honig","orcid":"https://orcid.org/0000-0001-9147-7450","observed_orcids":["https://orcid.org/0000-0001-9147-7450"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gerard Honig","raw_affiliation_strings":["Department of Psychiatry, UCSF, San Francisco, California, USA","Department of Psychiatry, UCSF, San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, UCSF, San Francisco, California, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Psychiatry, UCSF, San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112766226","display_name":"Marieke van der Hart","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marieke van der Hart","raw_affiliation_strings":["Department of Psychiatry, UCSF, San Francisco, California, USA","Department of Psychiatry, UCSF, San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, UCSF, San Francisco, California, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Psychiatry, UCSF, San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081095336","display_name":"Nina Y. Kishimoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nina Kishimoto","raw_affiliation_strings":["Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, California, USA","Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, California, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063288160","display_name":"Juehu Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Juehu Wang","raw_affiliation_strings":["Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, California, USA","Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, California, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066429469","display_name":"Soroku Yagihashi","orcid":"https://orcid.org/0000-0003-4255-774X","observed_orcids":["https://orcid.org/0000-0003-4255-774X"]},"institutions":[{"id":"https://openalex.org/I34077901","display_name":"Juntendo University","ror":"https://ror.org/01692sz90","country_code":"JP","type":"education","lineage":["https://openalex.org/I34077901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Soroku Yagihashi","raw_affiliation_strings":["Center for Therapeutic Innovations in Diabetes, Juntendo University Graduate School of Medicine, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Therapeutic Innovations in Diabetes, Juntendo University Graduate School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056780362","display_name":"Laurence H. Tecott","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laurence H Tecott","raw_affiliation_strings":["Department of Psychiatry, UCSF, San Francisco, California, USA","Department of Psychiatry, UCSF, San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, UCSF, San Francisco, California, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Psychiatry, UCSF, San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043895658","display_name":"Hirotaka Watada","orcid":"https://orcid.org/0000-0001-5961-1816","observed_orcids":["https://orcid.org/0000-0001-5961-1816"]},"institutions":[{"id":"https://openalex.org/I34077901","display_name":"Juntendo University","ror":"https://ror.org/01692sz90","country_code":"JP","type":"education","lineage":["https://openalex.org/I34077901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hirotaka Watada","raw_affiliation_strings":["Department of Medicine, Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan","Sportology Center, Juntendo University Graduate School of Medicine, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Metabolism and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]},{"raw_affiliation_string":"Sportology Center, Juntendo University Graduate School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I34077901"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057951350","display_name":"Michael S. German","orcid":"https://orcid.org/0000-0003-3833-7680","observed_orcids":["https://orcid.org/0000-0003-3833-7680"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael S German","raw_affiliation_strings":["Department of Medicine, UCSF, San Francisco, California, USA","Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, California, USA","Department of Medicine, UCSF, San Francisco, USA","Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, UCSF, San Francisco, California, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, California, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Department of Medicine, UCSF, San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]},{"raw_affiliation_string":"Diabetes Center, University of California\u2013San Francisco (UCSF), San Francisco, USA","institution_ids":["https://openalex.org/I180670191"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5057951350"],"corresponding_institution_ids":["https://openalex.org/I180670191"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":19.6105,"has_fulltext":false,"cited_by_count":601,"citation_normalized_percentile":{"value":0.99650441,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"16","issue":"7","first_page":"804","last_page":"808"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11171","display_name":"Diabetes and associated disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10673","display_name":"Gestational Diabetes Research and Management","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/serotonin","display_name":"serotonin","score":0.9950000047683716},{"id":"https://openalex.org/keywords/pancreatic-beta-cells","display_name":"pancreatic beta cells","score":0.8309999704360962},{"id":"https://openalex.org/keywords/beta-cell-mass","display_name":"beta-cell mass","score":0.8429999947547913},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.9670000076293945},{"id":"https://openalex.org/keywords/prolactin","display_name":"prolactin","score":0.7670000195503235},{"id":"https://openalex.org/keywords/placental-lactogen","display_name":"placental lactogen","score":0.984000027179718},{"id":"https://openalex.org/keywords/tph1","display_name":"tryptophan hydroxylase 1","score":0.9430000185966492},{"id":"https://openalex.org/keywords/htr2b","display_name":"HTR2B","score":0.8330000042915344},{"id":"https://openalex.org/keywords/impaired-glucose-tolerance","display_name":"impaired glucose tolerance","score":0.7120000123977661},{"id":"https://openalex.org/keywords/gestational-diabetes-mellitus","display_name":"gestational diabetes mellitus","score":0.9440000057220459},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.7120000123977661},{"id":"https://openalex.org/keywords/maternal-metabolism","display_name":"maternal metabolism","score":0.382999986410141}],"concepts":[{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.8157509565353394},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7785389423370361},{"id":"https://openalex.org/C2777064457","wikidata":"https://www.wikidata.org/wiki/Q1960869","display_name":"Placental lactogen","level":5,"score":0.6248078346252441},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.6023097038269043},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.5144117474555969},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.5132741928100586},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.49717238545417786},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.4725211262702942},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4431365430355072},{"id":"https://openalex.org/C2776828364","wikidata":"https://www.wikidata.org/wiki/Q1767180","display_name":"Beta cell","level":4,"score":0.4389984607696533},{"id":"https://openalex.org/C112446052","wikidata":"https://www.wikidata.org/wiki/Q422579","display_name":"Insulin receptor","level":4,"score":0.4287925064563751},{"id":"https://openalex.org/C2779064019","wikidata":"https://www.wikidata.org/wiki/Q66590068","display_name":"Prolactin","level":3,"score":0.412193238735199},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.4092346429824829},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.37723278999328613},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.3765206038951874},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.25607728958129883},{"id":"https://openalex.org/C2776953305","wikidata":"https://www.wikidata.org/wiki/Q1212935","display_name":"Placenta","level":4,"score":0.09868073463439941},{"id":"https://openalex.org/C165220095","wikidata":"https://www.wikidata.org/wiki/Q207524","display_name":"Islet","level":3,"score":0.09146979451179504},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005947","descriptor_name":"Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007515","descriptor_name":"Islets of Langerhans","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010928","descriptor_name":"Placental Lactogen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011270","descriptor_name":"Pregnancy, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011388","descriptor_name":"Prolactin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012701","descriptor_name":"Serotonin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014365","descriptor_name":"Tryptophan Hydroxylase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050417","descriptor_name":"Insulin-Secreting Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D050417","descriptor_name":"Insulin-Secreting Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1038/nm.2173","doi":"https://doi.org/10.1038/nm.2173","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nm.2173","pdf_url":null,"source":{"id":"https://openalex.org/S203256638","display_name":"Nature Medicine","issn_l":"1078-8956","issn":["1078-8956","1546-170X","1744-7933"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Medicine","raw_type":"journal-article"},{"id":"pmid:20581837","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20581837","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature medicine","raw_type":"Comparative Study"},{"id":"pmh:oai:pubmedcentral.nih.gov:2921604","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2921604","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nat Med","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.810.4627","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.810.4627","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/33/24/nihms210087.PMC2921604.pdf","raw_type":"text"},{"id":"pmh:oai:escholarship.org/ark:/13030/qt57p1w163","doi":null,"is_oa":false,"landing_page_url":"https://escholarship.org/uc/item/57p1w163","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nature medicine, vol 16, iss 7","raw_type":"article"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt57p1w163","doi":null,"is_oa":false,"landing_page_url":"https://escholarship.org/uc/item/57p1w163","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nature Medicine, vol 16, iss 7","raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2921604","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2921604","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nat Med","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4805044541","display_name":"Molecular Control of Pancreatic Islet Development","funder_award_id":"U19DK061245","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G575438376","display_name":"Differentiation in the Endocrine and Exocrine Pancreas","funder_award_id":"R01DK021344","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G8725134716","display_name":"Diabetes Research Center","funder_award_id":"P30DK063720","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W1937517990","https://openalex.org/W1973660081","https://openalex.org/W1982391086","https://openalex.org/W1993046413","https://openalex.org/W1994115989","https://openalex.org/W1995909110","https://openalex.org/W2007486557","https://openalex.org/W2020947476","https://openalex.org/W2035940741","https://openalex.org/W2047554789","https://openalex.org/W2049741741","https://openalex.org/W2052110444","https://openalex.org/W2057152032","https://openalex.org/W2058296375","https://openalex.org/W2061207954","https://openalex.org/W2064496466","https://openalex.org/W2085881951","https://openalex.org/W2098073452","https://openalex.org/W2098197630","https://openalex.org/W2113544353","https://openalex.org/W2125027724","https://openalex.org/W2133630249","https://openalex.org/W2146712490","https://openalex.org/W2148486284","https://openalex.org/W2153853866","https://openalex.org/W2160034631","https://openalex.org/W2162882842","https://openalex.org/W2164875032","https://openalex.org/W2168932510","https://openalex.org/W2169062460"],"related_works":["https://openalex.org/W7099562952","https://openalex.org/W2053475386","https://openalex.org/W2106183995","https://openalex.org/W2330919917","https://openalex.org/W6987431798","https://openalex.org/W2161395021","https://openalex.org/W4311358127","https://openalex.org/W3012344541","https://openalex.org/W3202997872","https://openalex.org/W1995275529"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":20},{"year":2025,"cited_by_count":34},{"year":2024,"cited_by_count":38},{"year":2023,"cited_by_count":29},{"year":2022,"cited_by_count":47},{"year":2021,"cited_by_count":41},{"year":2020,"cited_by_count":34},{"year":2019,"cited_by_count":44},{"year":2018,"cited_by_count":45},{"year":2017,"cited_by_count":48},{"year":2016,"cited_by_count":40},{"year":2015,"cited_by_count":42},{"year":2014,"cited_by_count":37},{"year":2013,"cited_by_count":30},{"year":2012,"cited_by_count":42}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}