{"id":"https://openalex.org/W2051459624","doi":"https://doi.org/10.1111/pan.12367","title":"Pain score guided morphine titration is risky and inappropriate","display_name":"Pain score guided morphine titration is risky and inappropriate","publication_year":2014,"publication_date":"2014-03-14","ids":{"openalex":"https://openalex.org/W2051459624","doi":"https://doi.org/10.1111/pan.12367","mag":"2051459624","pmid":"https://pubmed.ncbi.nlm.nih.gov/24628928"},"language":"en","primary_location":{"id":"doi:10.1111/pan.12367","doi":"https://doi.org/10.1111/pan.12367","is_oa":true,"landing_page_url":"https://doi.org/10.1111/pan.12367","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/pan.12367","source":{"id":"https://openalex.org/S192565471","display_name":"Pediatric Anesthesia","issn_l":"1155-5645","issn":["1155-5645","1460-9592"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Anesthesia","raw_type":"journal-article"},"volume":null,"type":"letter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/pan.12367","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001739052","display_name":"Terri Voepel\u2010Lewis","orcid":"https://orcid.org/0000-0001-9718-9695","observed_orcids":["https://orcid.org/0000-0001-9718-9695"]},"institutions":[{"id":"https://openalex.org/I4210114445","display_name":"Michigan Medicine","ror":"https://ror.org/01zcpa714","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210114445"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Terri Voepel\u2010Lewis","raw_affiliation_strings":["Department of Anesthesiology University of Michigan Health System Ann Arbor MI USA","University of Michigan Health System Department of Anesthesiology Ann Arbor MI USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology University of Michigan Health System Ann Arbor MI USA","institution_ids":["https://openalex.org/I4210114445"]},{"raw_affiliation_string":"University of Michigan Health System Department of Anesthesiology Ann Arbor MI USA","institution_ids":["https://openalex.org/I4210114445"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031254556","display_name":"Shobha V. Malviya","orcid":"https://orcid.org/0000-0003-2046-6820","observed_orcids":["https://orcid.org/0000-0003-2046-6820"]},"institutions":[{"id":"https://openalex.org/I4210114445","display_name":"Michigan Medicine","ror":"https://ror.org/01zcpa714","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210114445"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shobha Malviya","raw_affiliation_strings":["Department of Anesthesiology University of Michigan Health System Ann Arbor MI USA","University of Michigan Health System Department of Anesthesiology Ann Arbor MI USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology University of Michigan Health System Ann Arbor MI USA","institution_ids":["https://openalex.org/I4210114445"]},{"raw_affiliation_string":"University of Michigan Health System Department of Anesthesiology Ann Arbor MI USA","institution_ids":["https://openalex.org/I4210114445"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210114445"],"apc_list":{"value":4080,"currency":"USD","value_usd":4080},"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"24","issue":"4","first_page":"454","last_page":"456"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10189","display_name":"Anesthesia and Pain Management","score":0.6729000210762024,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10189","display_name":"Anesthesia and Pain Management","score":0.6729000210762024,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11199","display_name":"Pain Management and Opioid Use","score":0.24770000576972961,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10436","display_name":"Anesthesia and Sedative Agents","score":0.02759999968111515,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pain-scores","display_name":"pain scores","score":0.8450000286102295},{"id":"https://openalex.org/keywords/opioid-analgesia","display_name":"opioid analgesia","score":0.6039999723434448},{"id":"https://openalex.org/keywords/breastfeeding","display_name":"breastfeeding","score":0.47600001096725464},{"id":"https://openalex.org/keywords/drug-transfer-to-infant","display_name":"drug transfer to infant","score":0.5410000085830688},{"id":"https://openalex.org/keywords/preoperative-sedation","display_name":"preoperative sedation","score":0.7200000286102295},{"id":"https://openalex.org/keywords/lactating-women","display_name":"lactating women","score":0.6949999928474426},{"id":"https://openalex.org/keywords/prenatal-drug-exposure","display_name":"prenatal drug exposure","score":0.45100000500679016}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7922965288162231},{"id":"https://openalex.org/C2779526319","wikidata":"https://www.wikidata.org/wiki/Q615057","display_name":"Anesthesiology","level":2,"score":0.7716422080993652},{"id":"https://openalex.org/C23131810","wikidata":"https://www.wikidata.org/wiki/Q818574","display_name":"Observational study","level":2,"score":0.519043505191803},{"id":"https://openalex.org/C2991975920","wikidata":"https://www.wikidata.org/wiki/Q621261","display_name":"Pain medicine","level":3,"score":0.45054471492767334},{"id":"https://openalex.org/C2778805511","wikidata":"https://www.wikidata.org/wiki/Q1713","display_name":"Citation","level":2,"score":0.42940273880958557},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.30429500341415405},{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.22995981574058533},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.16304120421409607},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000701","descriptor_name":"Analgesics, Opioid","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D000701","descriptor_name":"Analgesics, Opioid","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009020","descriptor_name":"Morphine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D009020","descriptor_name":"Morphine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1111/pan.12367","doi":"https://doi.org/10.1111/pan.12367","is_oa":true,"landing_page_url":"https://doi.org/10.1111/pan.12367","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/pan.12367","source":{"id":"https://openalex.org/S192565471","display_name":"Pediatric Anesthesia","issn_l":"1155-5645","issn":["1155-5645","1460-9592"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Anesthesia","raw_type":"journal-article"},{"id":"pmid:24628928","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24628928","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Paediatric anaesthesia","raw_type":"Letter"},{"id":"pmh:oai:deepblue.lib.umich.edu:2027.42/106691","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/2027.42/106691","pdf_url":"https://hdl.handle.net/2027.42/106691","source":{"id":"https://openalex.org/S4306400393","display_name":"Deep Blue (University of Michigan)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I27837315","host_organization_name":"University of Michigan","host_organization_lineage":["https://openalex.org/I27837315"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1111/pan.12367","doi":"https://doi.org/10.1111/pan.12367","is_oa":true,"landing_page_url":"https://doi.org/10.1111/pan.12367","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/pan.12367","source":{"id":"https://openalex.org/S192565471","display_name":"Pediatric Anesthesia","issn_l":"1155-5645","issn":["1155-5645","1460-9592"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Anesthesia","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2051459624.pdf","grobid_xml":"https://content.openalex.org/works/W2051459624.grobid-xml"},"referenced_works_count":10,"referenced_works":["https://openalex.org/W1530217337","https://openalex.org/W1976162951","https://openalex.org/W1990893733","https://openalex.org/W2001954133","https://openalex.org/W2017411184","https://openalex.org/W2068289660","https://openalex.org/W2074211951","https://openalex.org/W2089262793","https://openalex.org/W2142302949","https://openalex.org/W4299952439"],"related_works":["https://openalex.org/W7096839662","https://openalex.org/W1983737552","https://openalex.org/W2321848809","https://openalex.org/W2089606674","https://openalex.org/W1779433015","https://openalex.org/W2027320855","https://openalex.org/W7099708058","https://openalex.org/W2419122576","https://openalex.org/W2011957830","https://openalex.org/W4230203045"],"abstract_inverted_index":{"states":[0],"that":[1],"'it":[2],"would":[3,83,92],"be":[4,17,57,84],"unethical":[5],"to":[6,26,39,95,98],"withhold":[7],"sedation":[8],"and":[9,13,33,43,73,81],"anesthesia":[10],"when":[11],"necessary'":[12],"'more":[14],"harm":[15],"may":[16,56],"inflicted":[18],"if":[19],"necessary":[20],"treatment":[21],"is":[22],"withheld'.As":[23],"a":[24],"corollary":[25],"this":[27],"statement,":[28],"based":[29],"on":[30],"current":[31],"evidence":[32],"considering":[34],"the":[35,41,44,46,53,70,78,99],"advantages":[36],"of":[37,48,109],"breast-feeding":[38],"both":[40],"mother":[42,55],"infant,":[45],"use":[47],"short-acting":[49],"sedative":[50],"premedication":[51],"for":[52],"nursing":[54],"considered":[58],"(albeit":[59],"with":[60,63],"caution":[61],"as":[62],"any":[64,74,106,110],"other":[65],"medication).Further":[66],"research":[67],"in":[68,77,86],"measuring":[69],"parent":[71],"drug":[72,111],"active":[75],"metabolites":[76],"infant":[79,100],"blood":[80],"urine":[82],"reassuring":[85],"determining":[87],"which":[88],"maternally":[89],"administrated":[90],"drugs":[91],"deliver":[93],"minimal":[94],"absent":[96],"exposure":[97],"(5).We":[101],"certainly":[102],"remain":[103],"concerned":[104],"over":[105],"possible":[107],"effect":[108],"transmitted":[112],"via":[113],"breast":[114],"milk":[115],"(5).":[116]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2014,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}