{"id":"https://openalex.org/W2051390959","doi":"https://doi.org/10.1371/journal.pone.0098077","title":"Oral and Vaginal Epithelial Cell Lines Bind and Transfer Cell-Free Infectious HIV-1 to Permissive Cells but Are Not Productively Infected","display_name":"Oral and Vaginal Epithelial Cell Lines Bind and Transfer Cell-Free Infectious HIV-1 to Permissive Cells but Are Not Productively Infected","publication_year":2014,"publication_date":"2014-05-23","ids":{"openalex":"https://openalex.org/W2051390959","doi":"https://doi.org/10.1371/journal.pone.0098077","mag":"2051390959","pmid":"https://pubmed.ncbi.nlm.nih.gov/24857971","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4032250"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0098077","doi":"https://doi.org/10.1371/journal.pone.0098077","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0098077","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0098077&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0098077&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077420251","display_name":"Arinder Kohli","orcid":"https://orcid.org/0000-0003-3199-3554","observed_orcids":["https://orcid.org/0000-0003-3199-3554"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Arinder Kohli","raw_affiliation_strings":["Department of Oral Immunology, Clinical and Diagnostic Sciences, King's College London Dental Institute, King's College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Immunology, Clinical and Diagnostic Sciences, King's College London Dental Institute, King's College London, London, United Kingdom","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029795509","display_name":"Ayesha Islam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Ayesha Islam","raw_affiliation_strings":["Department of Oral Immunology, Clinical and Diagnostic Sciences, King's College London Dental Institute, King's College London, London, United Kingdom; Department of Obstetrics and Gynecology, Boston University School of Medicine, Boston, Massachusetts, United States of America","Department of Obstetrics and Gynecology, Boston University School of Medicine, Boston, Massachusetts, United States of America","Department of Oral Immunology, Clinical and Diagnostic Sciences, King's College London Dental Institute, King's College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Immunology, Clinical and Diagnostic Sciences, King's College London Dental Institute, King's College London, London, United Kingdom; Department of Obstetrics and Gynecology, Boston University School of Medicine, Boston, Massachusetts, United States of America","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I183935753"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Boston University School of Medicine, Boston, Massachusetts, United States of America","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"Department of Oral Immunology, Clinical and Diagnostic Sciences, King's College London Dental Institute, King's College London, London, United Kingdom","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034810485","display_name":"David L. Moyes","orcid":"https://orcid.org/0000-0002-1657-918X","observed_orcids":["https://orcid.org/0000-0002-1657-918X"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David L. Moyes","raw_affiliation_strings":["Department of Oral Immunology, Clinical and Diagnostic Sciences, King's College London Dental Institute, King's College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Immunology, Clinical and Diagnostic Sciences, King's College London Dental Institute, King's College London, London, United Kingdom","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085099118","display_name":"Celia Murciano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I16097986","display_name":"Universitat de Val\u00e8ncia","ror":"https://ror.org/043nxc105","country_code":"ES","type":"education","lineage":["https://openalex.org/I16097986"]},{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["ES","GB"],"is_corresponding":false,"raw_author_name":"Celia Murciano","raw_affiliation_strings":["Department of Oral Immunology, Clinical and Diagnostic Sciences, King's College London Dental Institute, King's College London, London, United Kingdom; Department of Microbiology and Ecology, University of Valencia, Valencia, Spain","Department of Microbiology and Ecology, University of Valencia, Valencia, Spain","Department of Oral Immunology, Clinical and Diagnostic Sciences, King's College London Dental Institute, King's College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Immunology, Clinical and Diagnostic Sciences, King's College London Dental Institute, King's College London, London, United Kingdom; Department of Microbiology and Ecology, University of Valencia, Valencia, Spain","institution_ids":["https://openalex.org/I16097986","https://openalex.org/I183935753"]},{"raw_affiliation_string":"Department of Microbiology and Ecology, University of Valencia, Valencia, Spain","institution_ids":["https://openalex.org/I16097986"]},{"raw_affiliation_string":"Department of Oral Immunology, Clinical and Diagnostic Sciences, King's College London Dental Institute, King's College London, London, United Kingdom","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060454241","display_name":"Chengguo Shen","orcid":"https://orcid.org/0000-0003-2813-8143","observed_orcids":["https://orcid.org/0000-0003-2813-8143"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Chengguo Shen","raw_affiliation_strings":["Department of Oral Immunology, Clinical and Diagnostic Sciences, King's College London Dental Institute, King's College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Immunology, Clinical and Diagnostic Sciences, King's College London Dental Institute, King's College London, London, United Kingdom","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060076939","display_name":"Stephen Challacombe","orcid":"https://orcid.org/0000-0002-7327-6927","observed_orcids":["https://orcid.org/0000-0002-7327-6927"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stephen J. Challacombe","raw_affiliation_strings":["Department of Oral Immunology, Clinical and Diagnostic Sciences, King's College London Dental Institute, King's College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Immunology, Clinical and Diagnostic Sciences, King's College London Dental Institute, King's College London, London, United Kingdom","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015341755","display_name":"Julian R. Naglik","orcid":"https://orcid.org/0000-0002-8072-7917","observed_orcids":["https://orcid.org/0000-0002-8072-7917"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Julian R. Naglik","raw_affiliation_strings":["Department of Oral Immunology, Clinical and Diagnostic Sciences, King's College London Dental Institute, King's College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Immunology, Clinical and Diagnostic Sciences, King's College London Dental Institute, King's College London, London, United Kingdom","institution_ids":["https://openalex.org/I183935753"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5015341755"],"corresponding_institution_ids":["https://openalex.org/I183935753"],"apc_list":{"value":2382,"currency":"USD","value_usd":2382},"apc_paid":{"value":2382,"currency":"USD","value_usd":2382},"fwci":2.1466,"has_fulltext":true,"cited_by_count":39,"citation_normalized_percentile":{"value":0.87279279,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"9","issue":"5","first_page":"e98077","last_page":"e98077"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hiv-1","display_name":"HIV-1","score":0.9549999833106995},{"id":"https://openalex.org/keywords/oral-mucosa","display_name":"oral mucosa","score":0.8429999947547913},{"id":"https://openalex.org/keywords/vaginal-epithelium","display_name":"vaginal epithelium","score":0.8690000176429749},{"id":"https://openalex.org/keywords/epithelial-cell-lines","display_name":"epithelial cell lines","score":0.8420000076293945},{"id":"https://openalex.org/keywords/viral-receptor-expression","display_name":"viral receptor expression","score":0.6800000071525574},{"id":"https://openalex.org/keywords/cxcr4","display_name":"CXCR4","score":0.925000011920929},{"id":"https://openalex.org/keywords/ccr5","display_name":"CCR5","score":1.0},{"id":"https://openalex.org/keywords/viral-integration","display_name":"viral integration","score":0.5460000038146973},{"id":"https://openalex.org/keywords/transcytosis","display_name":"transcytosis","score":0.8159999847412109},{"id":"https://openalex.org/keywords/cell-to-cell-spread","display_name":"cell-to-cell transmission","score":0.6340000033378601},{"id":"https://openalex.org/keywords/vsv-g-pseudotyping","display_name":"VSV-G pseudotyping","score":0.7229999899864197},{"id":"https://openalex.org/keywords/endocytic-pathway","display_name":"endocytic pathway","score":0.5870000123977661},{"id":"https://openalex.org/keywords/viral-dissemination","display_name":"viral dissemination","score":0.5630000233650208},{"id":"https://openalex.org/keywords/fadu","display_name":"FADU","score":0.9700000286102295},{"id":"https://openalex.org/keywords/a431","display_name":"A431","score":1.0}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7364726066589355},{"id":"https://openalex.org/C529295009","wikidata":"https://www.wikidata.org/wiki/Q41301","display_name":"Epithelium","level":2,"score":0.6292247772216797},{"id":"https://openalex.org/C185350488","wikidata":"https://www.wikidata.org/wiki/Q615386","display_name":"Transcytosis","level":4,"score":0.5939494967460632},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5436148047447205},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.526621401309967},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.49498575925827026},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.4241303503513336},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.3867335915565491},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3424626588821411},{"id":"https://openalex.org/C28005876","wikidata":"https://www.wikidata.org/wiki/Q189814","display_name":"Endocytosis","level":3,"score":0.1635684370994568},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07560029625892639}],"mesh":[{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004279","descriptor_name":"DNA, Viral","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004279","descriptor_name":"DNA, Viral","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009061","descriptor_name":"Mouth Mucosa","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D011956","descriptor_name":"Receptors, Cell Surface","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014621","descriptor_name":"Vagina","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D014764","descriptor_name":"Viral Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D014764","descriptor_name":"Viral Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016662","descriptor_name":"Virus Integration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016679","descriptor_name":"Genome, Viral","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":9,"locations":[{"id":"doi:10.1371/journal.pone.0098077","doi":"https://doi.org/10.1371/journal.pone.0098077","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0098077","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0098077&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3009183","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4032250","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:24857971","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24857971","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4032250","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4032250/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.789.8450","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.789.8450","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/d4/b7/pone.0098077.PMC4032250.pdf","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:41d1cb63f7304dc796d87a7b3de43338","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/41d1cb63f7304dc796d87a7b3de43338","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 9, Iss 5, p e98077 (2014)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/1035574","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/_Oral_and_Vaginal_Epithelial_Cell_Lines_Bind_and_Transfer_Cell_Free_Infectious_HIV_1_to_Permissive_Cells_but_Are_Not_Productively_Infected_/1035574","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:kclpure.kcl.ac.uk:openaire/8984146c-16ab-4858-b056-718c36d03663","doi":null,"is_oa":true,"landing_page_url":"https://kclpure.kcl.ac.uk/portal/en/publications/8984146c-16ab-4858-b056-718c36d03663","pdf_url":null,"source":{"id":"https://openalex.org/S4306400216","display_name":"Research Portal (King's College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I183935753","host_organization_name":"King's College London","host_organization_lineage":["https://openalex.org/I183935753"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Kohli, A, Islam, A, Moyes, D L, Murciano, C, Shen, C, Challacombe, S J & Naglik, J R 2014, 'Oral and Vaginal Epithelial Cell Lines Bind and Transfer Cell-Free Infectious HIV-1 to Permissive Cells but Are Not Productively Infected', PL o S One , vol. 9, no. 5, e98077. https://doi.org/10.1371/journal.pone.0098077","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:roderic.uv.es:10550/44280","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10550/44280","pdf_url":null,"source":{"id":"https://openalex.org/S4306400245","display_name":"Repository of Digital Objects for Teaching Research and Culture (University of Valencia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I16097986","host_organization_name":"Universitat de Val\u00e8ncia","host_organization_lineage":["https://openalex.org/I16097986"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0098077","doi":"https://doi.org/10.1371/journal.pone.0098077","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0098077","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0098077&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2474712472","display_name":"The oral mucosal proteome: perturbation in HIV infection and Candida co infection","funder_award_id":"R01DE017514","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320312400","display_name":"King's College Hospital NHS Foundation Trust","ror":"https://ror.org/01n0k5m85"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320320187","display_name":"Federation of European Microbiological Societies","ror":"https://ror.org/058hv4b88"},{"id":"https://openalex.org/F4320320285","display_name":"King's College London","ror":"https://ror.org/0220mzb33"},{"id":"https://openalex.org/F4320337365","display_name":"National Institute of Dental and Craniofacial Research","ror":"https://ror.org/004a2wv92"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2051390959.pdf","grobid_xml":"https://content.openalex.org/works/W2051390959.grobid-xml"},"referenced_works_count":105,"referenced_works":["https://openalex.org/W33974125","https://openalex.org/W88954170","https://openalex.org/W93213490","https://openalex.org/W94955574","https://openalex.org/W104783186","https://openalex.org/W116133847","https://openalex.org/W1483387102","https://openalex.org/W1587835128","https://openalex.org/W1963218108","https://openalex.org/W1965192325","https://openalex.org/W1965493434","https://openalex.org/W1967802147","https://openalex.org/W1970217534","https://openalex.org/W1971038416","https://openalex.org/W1979285484","https://openalex.org/W1980217798","https://openalex.org/W1981315157","https://openalex.org/W1982034461","https://openalex.org/W1985136380","https://openalex.org/W1991371980","https://openalex.org/W1994854778","https://openalex.org/W2000245109","https://openalex.org/W2001148203","https://openalex.org/W2004363016","https://openalex.org/W2007763270","https://openalex.org/W2009124914","https://openalex.org/W2009761723","https://openalex.org/W2013122757","https://openalex.org/W2016131452","https://openalex.org/W2018469019","https://openalex.org/W2020012696","https://openalex.org/W2020871710","https://openalex.org/W2020896235","https://openalex.org/W2025543726","https://openalex.org/W2028603136","https://openalex.org/W2028661694","https://openalex.org/W2037793240","https://openalex.org/W2039062327","https://openalex.org/W2046445880","https://openalex.org/W2051946274","https://openalex.org/W2052302657","https://openalex.org/W2055295979","https://openalex.org/W2064844416","https://openalex.org/W2074620757","https://openalex.org/W2074750682","https://openalex.org/W2074866724","https://openalex.org/W2077413172","https://openalex.org/W2077494883","https://openalex.org/W2079803492","https://openalex.org/W2081329638","https://openalex.org/W2082118079","https://openalex.org/W2088747167","https://openalex.org/W2088968901","https://openalex.org/W2089876772","https://openalex.org/W2091869250","https://openalex.org/W2092288031","https://openalex.org/W2093211102","https://openalex.org/W2094822615","https://openalex.org/W2097250240","https://openalex.org/W2098021336","https://openalex.org/W2099689198","https://openalex.org/W2099776855","https://openalex.org/W2102237910","https://openalex.org/W2104206758","https://openalex.org/W2106066791","https://openalex.org/W2106619383","https://openalex.org/W2107506827","https://openalex.org/W2111069366","https://openalex.org/W2112112221","https://openalex.org/W2112631257","https://openalex.org/W2112688771","https://openalex.org/W2115808507","https://openalex.org/W2116720206","https://openalex.org/W2118223082","https://openalex.org/W2125218508","https://openalex.org/W2128069859","https://openalex.org/W2128858047","https://openalex.org/W2130976383","https://openalex.org/W2131850479","https://openalex.org/W2131853098","https://openalex.org/W2136669602","https://openalex.org/W2137567408","https://openalex.org/W2137882990","https://openalex.org/W2142042034","https://openalex.org/W2142148383","https://openalex.org/W2142309583","https://openalex.org/W2144535873","https://openalex.org/W2148000796","https://openalex.org/W2149317992","https://openalex.org/W2151061395","https://openalex.org/W2152279468","https://openalex.org/W2156643487","https://openalex.org/W2157900272","https://openalex.org/W2160645755","https://openalex.org/W2161024777","https://openalex.org/W2161083892","https://openalex.org/W2162703129","https://openalex.org/W2166230389","https://openalex.org/W2171081105","https://openalex.org/W2252989980","https://openalex.org/W2319686405","https://openalex.org/W2330901631","https://openalex.org/W2418848809","https://openalex.org/W2420959688","https://openalex.org/W6601348139"],"related_works":["https://openalex.org/W2136669602","https://openalex.org/W2046445880","https://openalex.org/W2286313803","https://openalex.org/W2328657095","https://openalex.org/W2020012696","https://openalex.org/W2152410485","https://openalex.org/W2068393986","https://openalex.org/W2149024774","https://openalex.org/W3137572231","https://openalex.org/W2098021336"],"abstract_inverted_index":{"The":[0],"majority":[1],"of":[2,18,28,44,60,67,182,197,250,268,276],"HIV-1":[3,31,45,88,96,128,137,183,188,231,248,277],"infections":[4],"worldwide":[5],"are":[6,165],"acquired":[7],"via":[8,156,180,233],"mucosal":[9],"surfaces.":[10],"However,":[11,187],"unlike":[12],"the":[13,16,20,42,68,234],"vaginal":[14,51,80,147,162,219],"mucosa,":[15],"issue":[17],"whether":[19,95,104,111],"oral":[21,49,69,160,217],"mucosa":[22],"can":[23,114,264],"act":[24,265],"as":[25,190,266],"a":[26,75],"portal":[27],"entry":[29],"for":[30],"infection":[32,107,229,249],"remains":[33],"controversial.":[34],"To":[35],"address":[36],"potential":[37],"differences":[38],"with":[39,74],"regard":[40],"to":[41,48,85,117,123,135,167,171,224,254,278],"fate":[43],"after":[46],"exposure":[47],"and":[50,63,71,91,109,132,146,152,161,195,202,218,227,274],"epithelium,":[52],"we":[53,141],"utilized":[54],"two":[55],"epithelial":[56,100,148,163,185,212,220,251,262],"cell":[57,76,213],"lines":[58],"representative":[59],"buccal":[61],"(TR146)":[62],"pharyngeal":[64,145],"(FaDu)":[65],"sites":[66],"cavity":[70],"compared":[72],"them":[73],"line":[77],"derived":[78],"from":[79],"epithelium":[81],"(A431)":[82],"in":[83,210],"order":[84],"determine":[86],"(i)":[87],"receptor":[89],"gene":[90,199],"protein":[92,130,205],"expression,":[93],"(ii)":[94],"genome":[97],"integration":[98,226],"into":[99],"cells":[101,149,164,173,221,252,263],"occurs,":[102],"(iii)":[103],"productive":[105,228,247],"viral":[106,270],"ensues,":[108],"(iv)":[110],"infectious":[112,169],"virus":[113,126,170],"be":[115],"transferred":[116],"permissive":[118,172,279],"cells.":[119,186,280],"Using":[120],"flow":[121],"cytometry":[122],"measure":[124],"captured":[125],"by":[127,192,238],"gp120":[129],"detection":[131],"western":[133],"blot":[134],"detect":[136],"p24":[138],"gag":[139],"protein,":[140],"demonstrate":[142,242],"that":[143,243,261],"buccal,":[144],"capture":[150],"CXCR4-":[151],"CCR5-utilising":[153],"virus,":[154],"probably":[155],"non-canonical":[157],"receptors.":[158],"Both":[159],"able":[166,223],"transfer":[168,275],"either":[174,211],"directly":[175],"through":[176,272],"cell-cell":[177],"attachment":[178,273],"or":[179],"transcytosis":[181],"across":[184],"integration,":[189],"measured":[191],"real-time":[193],"PCR":[194],"presence":[196],"early":[198],"mRNA":[200],"transcripts":[201],"de":[203],"novo":[204],"production":[206,257],"were":[207,222],"not":[208],"detected":[209],"type.":[214],"Importantly,":[215],"both":[216],"support":[225],"if":[230],"entered":[232],"endocytic":[235],"pathway":[236],"driven":[237],"VSV-G.":[239],"Our":[240],"data":[241],"under":[244],"normal":[245],"conditions":[246],"leading":[253],"progeny":[255],"virion":[256],"is":[258],"unlikely,":[259],"but":[260],"mediators":[267],"systemic":[269],"dissemination":[271]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}
