{"id":"https://openalex.org/W2051293475","doi":"https://doi.org/10.3171/2014.10.jns14911","title":"High-resolution18F-fluorodeoxyglucose positron emission tomography and magnetic resonance imaging for pituitary adenoma detection in Cushing disease","display_name":"High-resolution18F-fluorodeoxyglucose positron emission tomography and magnetic resonance imaging for pituitary adenoma detection in Cushing disease","publication_year":2014,"publication_date":"2014-12-05","ids":{"openalex":"https://openalex.org/W2051293475","doi":"https://doi.org/10.3171/2014.10.jns14911","mag":"2051293475","pmid":"https://pubmed.ncbi.nlm.nih.gov/25479121"},"language":"en","primary_location":{"id":"doi:10.3171/2014.10.jns14911","doi":"https://doi.org/10.3171/2014.10.jns14911","is_oa":true,"landing_page_url":"https://doi.org/10.3171/2014.10.jns14911","pdf_url":"https://thejns.org/downloadpdf/journals/j-neurosurg/122/4/article-p791.pdf","source":{"id":"https://openalex.org/S1995308","display_name":"Journal of neurosurgery","issn_l":"0022-3085","issn":["0022-3085","1933-0693"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316861","host_organization_name":"American Association of Neurological Surgeons","host_organization_lineage":["https://openalex.org/P4310316861"],"host_organization_lineage_names":["American Association of Neurological Surgeons"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurosurgery","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://thejns.org/downloadpdf/journals/j-neurosurg/122/4/article-p791.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091098904","display_name":"Prashant Chittiboina","orcid":"https://orcid.org/0000-0001-9349-4756","observed_orcids":["https://orcid.org/0000-0001-9349-4756"]},"institutions":[{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Prashant Chittiboina","raw_affiliation_strings":["Surgical Neurology Branch, National Institutes of Neurological Disorders and Stroke;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Surgical Neurology Branch, National Institutes of Neurological Disorders and Stroke;","institution_ids":["https://openalex.org/I4210110767"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113878438","display_name":"Blake K. Montgomery","orcid":"https://orcid.org/0000-0001-7768-7929","observed_orcids":["https://orcid.org/0000-0001-7768-7929"]},"institutions":[{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Blake K. Montgomery","raw_affiliation_strings":["Surgical Neurology Branch, National Institutes of Neurological Disorders and Stroke;","1Surgical Neurology Branch, National Institutes of Neurological Disorders and Stroke;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Surgical Neurology Branch, National Institutes of Neurological Disorders and Stroke;","institution_ids":["https://openalex.org/I4210110767"]},{"raw_affiliation_string":"1Surgical Neurology Branch, National Institutes of Neurological Disorders and Stroke;","institution_ids":["https://openalex.org/I4210110767"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015755209","display_name":"Corina Millo","orcid":"https://orcid.org/0009-0008-3035-093X","observed_orcids":["https://orcid.org/0009-0008-3035-093X"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Corina Millo","raw_affiliation_strings":["Positron Emission Tomography Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland; and","2Positron Emission Tomography Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Positron Emission Tomography Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland; and","institution_ids":["https://openalex.org/I1299303238"]},{"raw_affiliation_string":"2Positron Emission Tomography Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland; and","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103580801","display_name":"Peter Herscovitch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter Herscovitch","raw_affiliation_strings":["Positron Emission Tomography Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland; and","2Positron Emission Tomography Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Positron Emission Tomography Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland; and","institution_ids":["https://openalex.org/I1299303238"]},{"raw_affiliation_string":"2Positron Emission Tomography Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland; and","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043842805","display_name":"Russell R. Lonser","orcid":"https://orcid.org/0000-0002-8007-707X","observed_orcids":["https://orcid.org/0000-0002-8007-707X"]},"institutions":[{"id":"https://openalex.org/I2802841970","display_name":"The Ohio State University Wexner Medical Center","ror":"https://ror.org/00c01js51","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802841970"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]},{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Russell R. Lonser","raw_affiliation_strings":["Department of Neurological Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio","Surgical Neurology Branch, National Institutes of Neurological Disorders and Stroke;","3Department of Neurological Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurological Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio","institution_ids":["https://openalex.org/I2802841970","https://openalex.org/I52357470"]},{"raw_affiliation_string":"Surgical Neurology Branch, National Institutes of Neurological Disorders and Stroke;","institution_ids":["https://openalex.org/I4210110767"]},{"raw_affiliation_string":"3Department of Neurological Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio","institution_ids":["https://openalex.org/I2802841970","https://openalex.org/I52357470"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.3248,"has_fulltext":true,"cited_by_count":64,"citation_normalized_percentile":{"value":0.94576039,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"122","issue":"4","first_page":"791","last_page":"797"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10832","display_name":"Pituitary Gland Disorders and Treatments","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10832","display_name":"Pituitary Gland Disorders and Treatments","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10754","display_name":"Neuroendocrine Tumor Research Advances","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cushing-disease","display_name":"Cushing's disease","score":0.9649999737739563},{"id":"https://openalex.org/keywords/pituitary-adenoma","display_name":"pituitary adenoma","score":0.9459999799728394},{"id":"https://openalex.org/keywords/corticotroph-adenoma","display_name":"corticotroph adenoma","score":0.8840000033378601},{"id":"https://openalex.org/keywords/18f-fdg-pet","display_name":"18F-FDG PET","score":0.9430000185966492},{"id":"https://openalex.org/keywords/high-resolution-pet","display_name":"high-resolution PET","score":0.8330000042915344},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"magnetic resonance imaging","score":0.5460000038146973},{"id":"https://openalex.org/keywords/acth","display_name":"ACTH","score":0.4560000002384186},{"id":"https://openalex.org/keywords/crh-stimulation-test","display_name":"CRH stimulation test","score":0.7900000214576721},{"id":"https://openalex.org/keywords/standardized-uptake-value","display_name":"standardized uptake value","score":0.7170000076293945},{"id":"https://openalex.org/keywords/tumor-detection","display_name":"tumor detection","score":0.5299999713897705},{"id":"https://openalex.org/keywords/dural-invasion","display_name":"dural invasion","score":0.6209999918937683},{"id":"https://openalex.org/keywords/tumor-volume","display_name":"tumor volume","score":0.6549999713897705},{"id":"https://openalex.org/keywords/preoperative-imaging","display_name":"preoperative imaging","score":0.5440000295639038},{"id":"https://openalex.org/keywords/pituitary-surgery","display_name":"pituitary surgery","score":0.515999972820282}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8735392093658447},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.7020823955535889},{"id":"https://openalex.org/C2779318953","wikidata":"https://www.wikidata.org/wiki/Q864296","display_name":"Pituitary adenoma","level":3,"score":0.6520570516586304},{"id":"https://openalex.org/C2777428134","wikidata":"https://www.wikidata.org/wiki/Q272741","display_name":"Adenoma","level":2,"score":0.6077768206596375},{"id":"https://openalex.org/C2776810848","wikidata":"https://www.wikidata.org/wiki/Q1947304","display_name":"Cushing's disease","level":3,"score":0.6062296032905579},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.605228841304779},{"id":"https://openalex.org/C2775842073","wikidata":"https://www.wikidata.org/wiki/Q208376","display_name":"Positron emission tomography","level":2,"score":0.4724719226360321},{"id":"https://openalex.org/C2910559741","wikidata":"https://www.wikidata.org/wiki/Q219102","display_name":"Cushing Disease","level":3,"score":0.41612523794174194},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.32668769359588623},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.27946943044662476},{"id":"https://openalex.org/C2779435821","wikidata":"https://www.wikidata.org/wiki/Q219102","display_name":"Cushing syndrome","level":2,"score":0.25137805938720703},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2169225513935089},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.09824922680854797}],"mesh":[{"descriptor_ui":"D000236","descriptor_name":"Adenoma","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D000236","descriptor_name":"Adenoma","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D000236","descriptor_name":"Adenoma","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D000236","descriptor_name":"Adenoma","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D000236","descriptor_name":"Adenoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000236","descriptor_name":"Adenoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000236","descriptor_name":"Adenoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000236","descriptor_name":"Adenoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000324","descriptor_name":"Adrenocorticotropic Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000324","descriptor_name":"Adrenocorticotropic Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000324","descriptor_name":"Adrenocorticotropic Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000324","descriptor_name":"Adrenocorticotropic Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010911","descriptor_name":"Pituitary Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D010911","descriptor_name":"Pituitary Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D010911","descriptor_name":"Pituitary Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D010911","descriptor_name":"Pituitary Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D010911","descriptor_name":"Pituitary Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010911","descriptor_name":"Pituitary Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010911","descriptor_name":"Pituitary Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010911","descriptor_name":"Pituitary Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D019275","descriptor_name":"Radiopharmaceuticals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019275","descriptor_name":"Radiopharmaceuticals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019275","descriptor_name":"Radiopharmaceuticals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019275","descriptor_name":"Radiopharmaceuticals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019788","descriptor_name":"Fluorodeoxyglucose F18","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019788","descriptor_name":"Fluorodeoxyglucose F18","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019788","descriptor_name":"Fluorodeoxyglucose F18","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019788","descriptor_name":"Fluorodeoxyglucose F18","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D047748","descriptor_name":"Pituitary ACTH Hypersecretion","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D047748","descriptor_name":"Pituitary ACTH Hypersecretion","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D047748","descriptor_name":"Pituitary ACTH Hypersecretion","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D047748","descriptor_name":"Pituitary ACTH Hypersecretion","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D047748","descriptor_name":"Pituitary ACTH Hypersecretion","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D047748","descriptor_name":"Pituitary ACTH Hypersecretion","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D047748","descriptor_name":"Pituitary ACTH Hypersecretion","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D047748","descriptor_name":"Pituitary ACTH Hypersecretion","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064847","descriptor_name":"Multimodal Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064847","descriptor_name":"Multimodal Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064847","descriptor_name":"Multimodal Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064847","descriptor_name":"Multimodal Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3171/2014.10.jns14911","doi":"https://doi.org/10.3171/2014.10.jns14911","is_oa":true,"landing_page_url":"https://doi.org/10.3171/2014.10.jns14911","pdf_url":"https://thejns.org/downloadpdf/journals/j-neurosurg/122/4/article-p791.pdf","source":{"id":"https://openalex.org/S1995308","display_name":"Journal of neurosurgery","issn_l":"0022-3085","issn":["0022-3085","1933-0693"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316861","host_organization_name":"American Association of Neurological Surgeons","host_organization_lineage":["https://openalex.org/P4310316861"],"host_organization_lineage_names":["American Association of Neurological Surgeons"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurosurgery","raw_type":"journal-article"},{"id":"pmid:25479121","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25479121","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neurosurgery","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5091074","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5091074","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Neurosurg","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3171/2014.10.jns14911","doi":"https://doi.org/10.3171/2014.10.jns14911","is_oa":true,"landing_page_url":"https://doi.org/10.3171/2014.10.jns14911","pdf_url":"https://thejns.org/downloadpdf/journals/j-neurosurg/122/4/article-p791.pdf","source":{"id":"https://openalex.org/S1995308","display_name":"Journal of neurosurgery","issn_l":"0022-3085","issn":["0022-3085","1933-0693"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316861","host_organization_name":"American Association of Neurological Surgeons","host_organization_lineage":["https://openalex.org/P4310316861"],"host_organization_lineage_names":["American Association of Neurological Surgeons"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurosurgery","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9922999739646912,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.5600000023841858,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G9000083331","display_name":null,"funder_award_id":"ZIA NS003150","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306080","display_name":"Foundation for the National Institutes of Health","ror":"https://ror.org/00k86s890"},{"id":"https://openalex.org/F4320306082","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90"},{"id":"https://openalex.org/F4320306134","display_name":"Doris Duke Charitable Foundation","ror":"https://ror.org/04n65rp89"},{"id":"https://openalex.org/F4320307765","display_name":"Pfizer","ror":"https://ror.org/01xdqrp08"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2051293475.pdf","grobid_xml":"https://content.openalex.org/works/W2051293475.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W1524984288","https://openalex.org/W1528166189","https://openalex.org/W1601850241","https://openalex.org/W1964892263","https://openalex.org/W1969677811","https://openalex.org/W1981993450","https://openalex.org/W1982835104","https://openalex.org/W1990995386","https://openalex.org/W1991379748","https://openalex.org/W1997429901","https://openalex.org/W2032663718","https://openalex.org/W2059374715","https://openalex.org/W2068087304","https://openalex.org/W2072368530","https://openalex.org/W2080329991","https://openalex.org/W2092821152","https://openalex.org/W2093236226","https://openalex.org/W2101263322","https://openalex.org/W2112650105"],"related_works":["https://openalex.org/W2379904645","https://openalex.org/W2382019598","https://openalex.org/W2621002353","https://openalex.org/W2368164637","https://openalex.org/W4285797717","https://openalex.org/W1975953955","https://openalex.org/W2355313044","https://openalex.org/W2621277632","https://openalex.org/W3032366046","https://openalex.org/W2064769128"],"abstract_inverted_index":{"OBJECT":[0],"High-resolution":[1],"PET":[2],"(hrPET)":[3],"performed":[4],"using":[5],"a":[6,14,120,234,237,245],"high-resolution":[7],"research":[8],"tomograph":[9],"is":[10,300,308],"reported":[11],"as":[12],"having":[13],"resolution":[15],"of":[16,35,46,127,319],"2":[17],"mm":[18],"and":[19,43,62,67,84,96,104,131,194,206,209,221,299,313],"could":[20],"be":[21],"used":[22],"to":[23,94,324],"detect":[24,294],"corticotroph":[25,297],"adenomas":[26,48,232,243,258,273,280,298,330],"through":[27],"uptake":[28,77,141],"of(18)F-fluorodeoxyglucose":[29],"((18)F-FDG).":[30],"To":[31],"determine":[32],"the":[33,39,212,317],"sensitivity":[34],"this":[36],"imaging":[37,292],"modality,":[38],"authors":[40],"compared(18)F-FDG":[41],"hrPET":[42,61,83,138,176,201,270,291,312],"MRI":[44,63,88,118,263,307,315],"detection":[45,318],"pituitary":[47,121,321],"in":[49,123,146,316,331],"Cushing":[50],"disease":[51],"(CD).":[52],"METHODS":[53],"Consecutive":[54],"patients":[55,101,125,133,148],"with":[56,87,143,181,211],"CD":[57],"who":[58],"underwent":[59],"preoperative(18)F-FDG":[60],"(spin":[64],"echo":[65],"[SE]":[66],"spoiled":[68],"gradient":[69],"recalled":[70],"[SPGR]":[71],"sequences)":[72],"were":[73,80,85,92,107,198,259,266,285],"prospectively":[74],"analyzed.":[75],"Standardized":[76],"values":[78],"(SUVs)":[79],"calculated":[81],"from":[82],"compared":[86],"findings.":[89,98],"Imaging":[90],"findings":[91],"correlated":[93,210],"operative":[95],"histological":[97],"RESULTS":[99],"Ten":[100],"(7":[102],"females":[103],"3":[105],"males)":[106],"included":[108],"(mean":[109],"age":[110],"30.8":[111],"\u00b1":[112],"19.3":[113],"years;":[114],"range":[115,152],"11-59":[116],"years).":[117],"revealed":[119],"adenoma":[122,145,150],"4":[124,147],"(40%":[126],"patients)":[128],"on":[129,135,261,276,283],"SE":[130,277,304,314],"7":[132],"(70%)":[134],"SPGR":[136,262,306],"sequences.(18)F-FDG":[137],"demonstrated":[139],"increased(18)F-FDG":[140],"consistent":[142],"an":[144],"(40%;":[149],"size":[151],"3-14":[153],"mm).":[154],"Maximum":[155],"SUV":[156,214,223],"was":[157,178],"significantly":[158],"higher":[159],"for(18)F-FDG":[160,173],"hrPET-positive":[161,231,329],"tumors":[162],"(difference":[163],"=":[164,170,185,191,204,216,219,225,228,255],"5.1,":[165],"95%":[166],"CI":[167],"2.1-8.1;":[168],"p":[169,218,227],"0.004)":[171],"than":[172,236,247,303],"hrPET-negative":[174,242],"tumors.(18)F-FDG":[175],"positivity":[177,202],"not":[179,267,274,281],"associated":[180,199],"tumor":[182],"volume":[183],"(p":[184,190,203,254],"0.2)":[186],"or":[187],"dural":[188],"invasion":[189],"0.5).":[192],"Midnight":[193],"morning":[195],"ACTH":[196,239,249],"levels":[197],"with(18)F-FDG":[200],"0.01":[205],"0.04,":[207],"respectively)":[208],"maximum":[213],"(R":[215,224],"0.9;":[217],"0.001)":[220],"average":[222],"0.8;":[226],"0.01).":[229],"All(18)F-FDG":[230],"had":[233,244],"less":[235],"180%":[238,248],"increase":[240,250],"and(18)F-FDG":[241],"greater":[246],"after":[251],"CRH":[252,325],"stimulation":[253,326],"0.03).":[256],"Three":[257],"detected":[260,268,275,282,286],"sequences":[264],"that":[265],"by(18)F-FDG":[269],"imaging.":[271],"Two":[272],"(but":[278],"no":[279],"SPGR)":[284],"on(18)F-FDG":[287],"hrPET.":[288],"CONCLUSIONS":[289],"While(18)F-FDG":[290],"can":[293,327],"small":[295],"functioning":[296],"more":[301,309],"sensitive":[302,310],"MRI,":[305],"than(18)F-FDG":[311],"CD-associated":[320],"adenomas.":[322],"Response":[323],"predict(18)F-FDG":[328],"CD.":[332]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":4}],"updated_date":"2026-10-08T09:06:37.294493","created_date":"2025-10-10T00:00:00"}