{"id":"https://openalex.org/W2051277299","doi":"https://doi.org/10.1016/0021-9673(95)00803-9","title":"Separation of ivermectin components by high-speed counter-current chromatography","display_name":"Separation of ivermectin components by high-speed counter-current chromatography","publication_year":1996,"publication_date":"1996-02-01","ids":{"openalex":"https://openalex.org/W2051277299","doi":"https://doi.org/10.1016/0021-9673(95)00803-9","mag":"2051277299"},"language":"en","primary_location":{"id":"doi:10.1016/0021-9673(95)00803-9","doi":"https://doi.org/10.1016/0021-9673(95)00803-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0021-9673(95)00803-9","pdf_url":null,"source":{"id":"https://openalex.org/S176136234","display_name":"Journal of Chromatography A","issn_l":"0021-9673","issn":["0021-9673","1873-3778"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chromatography A","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025091607","display_name":"Hisao Oka","orcid":"https://orcid.org/0009-0000-4377-184X","observed_orcids":["https://orcid.org/0009-0000-4377-184X"]},"institutions":[{"id":"https://openalex.org/I4405285639","display_name":"Aichi Prefectural Institute of Public Health","ror":"https://ror.org/05v44vg62","country_code":"JP","type":"government","lineage":["https://openalex.org/I4210162198","https://openalex.org/I4405285639"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hisao Oka","raw_affiliation_strings":["Aichi Prefectual Institute of Public Health, Tsuji-machi, Kita-ku, Nagoya 462, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aichi Prefectual Institute of Public Health, Tsuji-machi, Kita-ku, Nagoya 462, Japan","institution_ids":["https://openalex.org/I4405285639"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075500812","display_name":"Yoshimoto Ikai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285639","display_name":"Aichi Prefectural Institute of Public Health","ror":"https://ror.org/05v44vg62","country_code":"JP","type":"government","lineage":["https://openalex.org/I4210162198","https://openalex.org/I4405285639"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshimoto Ikai","raw_affiliation_strings":["Aichi Prefectual Institute of Public Health, Tsuji-machi, Kita-ku, Nagoya 462, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aichi Prefectual Institute of Public Health, Tsuji-machi, Kita-ku, Nagoya 462, Japan","institution_ids":["https://openalex.org/I4405285639"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075335546","display_name":"Junko Hayakawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285639","display_name":"Aichi Prefectural Institute of Public Health","ror":"https://ror.org/05v44vg62","country_code":"JP","type":"government","lineage":["https://openalex.org/I4210162198","https://openalex.org/I4405285639"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Junko Hayakawa","raw_affiliation_strings":["Aichi Prefectual Institute of Public Health, Tsuji-machi, Kita-ku, Nagoya 462, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aichi Prefectual Institute of Public Health, Tsuji-machi, Kita-ku, Nagoya 462, Japan","institution_ids":["https://openalex.org/I4405285639"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083582078","display_name":"Kenichi Harada","orcid":"https://orcid.org/0000-0001-6000-0553","observed_orcids":["https://orcid.org/0000-0001-6000-0553"]},"institutions":[{"id":"https://openalex.org/I96636082","display_name":"Meijo University","ror":"https://ror.org/04h42fc75","country_code":"JP","type":"education","lineage":["https://openalex.org/I96636082"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ken-ichi Harada","raw_affiliation_strings":["Faculty of Pharmacy, Meijo University, Tempaku, Nagoya, 468, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmacy, Meijo University, Tempaku, Nagoya, 468, Japan","institution_ids":["https://openalex.org/I96636082"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062767298","display_name":"Mokoto Suzuki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I96636082","display_name":"Meijo University","ror":"https://ror.org/04h42fc75","country_code":"JP","type":"education","lineage":["https://openalex.org/I96636082"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mokoto Suzuki","raw_affiliation_strings":["Faculty of Pharmacy, Meijo University, Tempaku, Nagoya, 468, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmacy, Meijo University, Tempaku, Nagoya, 468, Japan","institution_ids":["https://openalex.org/I96636082"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112717375","display_name":"Atsuko Shimizu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Atsuko Shimizu","raw_affiliation_strings":["Ichimiya Public Health Center, Aichi Prefecture, Kogane-machi, Ichimiya 491, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ichimiya Public Health Center, Aichi Prefecture, Kogane-machi, Ichimiya 491, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043571039","display_name":"Tomoko Hayashi","orcid":"https://orcid.org/0000-0002-9589-8348","observed_orcids":["https://orcid.org/0000-0002-9589-8348"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tomoko Hayashi","raw_affiliation_strings":["Ichimiya Public Health Center, Aichi Prefecture, Kogane-machi, Ichimiya 491, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ichimiya Public Health Center, Aichi Prefecture, Kogane-machi, Ichimiya 491, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053631614","display_name":"Kazue Takeba","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210099527","display_name":"Tokyo Metropolitan Institute of Public Health","ror":"https://ror.org/00w1zvy92","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210099527"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazue Takeba","raw_affiliation_strings":["The Tokyo Metropolitan Research Laboratory of Public Health, Hyakunin-cho, Shinjuku-ku, Tokyo 169, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Tokyo Metropolitan Research Laboratory of Public Health, Hyakunin-cho, Shinjuku-ku, Tokyo 169, Japan","institution_ids":["https://openalex.org/I4210099527"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111535170","display_name":"Hiroyuki Nakazawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36296616","display_name":"Hoshi University","ror":"https://ror.org/01mrvbd33","country_code":"JP","type":"education","lineage":["https://openalex.org/I36296616"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroyuki Nakazawa","raw_affiliation_strings":["Faculty of Pharmaceutical Science, Hoshi University, Ebara-2-4-41, Shinagawa-ku, Tokyo 142, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Science, Hoshi University, Ebara-2-4-41, Shinagawa-ku, Tokyo 142, Japan","institution_ids":["https://openalex.org/I36296616"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029128268","display_name":"Yoichiro Ito","orcid":"https://orcid.org/0000-0001-9018-295X","observed_orcids":["https://orcid.org/0000-0001-9018-295X"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yoichiro Ito","raw_affiliation_strings":["Laboratory Biophysical Chemistry, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory Biophysical Chemistry, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4040,"currency":"USD","value_usd":4040},"apc_paid":null,"fwci":1.6251,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.79974467,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"723","issue":"1","first_page":"61","last_page":"68"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13128","display_name":"Chromatography in Natural Products","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13128","display_name":"Chromatography in Natural Products","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10908","display_name":"Analytical Chemistry and Chromatography","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11709","display_name":"Traditional Chinese Medicine Analysis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ivermectin","display_name":"ivermectin","score":0.996999979019165},{"id":"https://openalex.org/keywords/high-speed-countercurrent-chromatography","display_name":"high-speed countercurrent chromatography","score":0.8600000143051147},{"id":"https://openalex.org/keywords/macrocyclic-lactones","display_name":"macrocyclic lactones","score":0.6909999847412109},{"id":"https://openalex.org/keywords/impurity-removal","display_name":"impurity removal","score":0.3840000033378601}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8880277872085571},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.8517294526100159},{"id":"https://openalex.org/C2777499811","wikidata":"https://www.wikidata.org/wiki/Q415178","display_name":"Ivermectin","level":2,"score":0.5657638907432556},{"id":"https://openalex.org/C63258622","wikidata":"https://www.wikidata.org/wiki/Q1498317","display_name":"Countercurrent chromatography","level":3,"score":0.5155934691429138},{"id":"https://openalex.org/C2776061190","wikidata":"https://www.wikidata.org/wiki/Q7451805","display_name":"Separation (statistics)","level":2,"score":0.4677695631980896},{"id":"https://openalex.org/C148043351","wikidata":"https://www.wikidata.org/wiki/Q4456944","display_name":"Current (fluid)","level":2,"score":0.4310384690761566},{"id":"https://openalex.org/C179998833","wikidata":"https://www.wikidata.org/wiki/Q381233","display_name":"High-performance liquid chromatography","level":2,"score":0.2713586091995239},{"id":"https://openalex.org/C90856448","wikidata":"https://www.wikidata.org/wiki/Q431","display_name":"Zoology","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.0},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/0021-9673(95)00803-9","doi":"https://doi.org/10.1016/0021-9673(95)00803-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0021-9673(95)00803-9","pdf_url":null,"source":{"id":"https://openalex.org/S176136234","display_name":"Journal of Chromatography A","issn_l":"0021-9673","issn":["0021-9673","1873-3778"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chromatography A","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W619665994","https://openalex.org/W1997175521","https://openalex.org/W1999531955","https://openalex.org/W2006810880","https://openalex.org/W2019646456","https://openalex.org/W2022072541","https://openalex.org/W2070059667","https://openalex.org/W2088295090"],"related_works":["https://openalex.org/W2023519562","https://openalex.org/W2087367383","https://openalex.org/W2088855771","https://openalex.org/W2359269282","https://openalex.org/W2348343458","https://openalex.org/W1999531955","https://openalex.org/W2000689265","https://openalex.org/W1997436395","https://openalex.org/W2035462829","https://openalex.org/W1977622265"],"abstract_inverted_index":null,"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-09T09:14:12.587421","created_date":"2016-06-24T00:00:00"}