{"id":"https://openalex.org/W2051270002","doi":"https://doi.org/10.1055/s-1987-27922","title":"A Facile Method for the Preparation of 2-Substituted Pyrimidin-4(3H)-ones by a Retro-Diels-Alder Reaction","display_name":"A Facile Method for the Preparation of 2-Substituted Pyrimidin-4(3H)-ones by a Retro-Diels-Alder Reaction","publication_year":1987,"publication_date":"1987-01-01","ids":{"openalex":"https://openalex.org/W2051270002","doi":"https://doi.org/10.1055/s-1987-27922","mag":"2051270002"},"language":"en","primary_location":{"id":"doi:10.1055/s-1987-27922","doi":"https://doi.org/10.1055/s-1987-27922","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-1987-27922","pdf_url":null,"source":{"id":"https://openalex.org/S197964166","display_name":"Synthesis","issn_l":"0039-7881","issn":["0039-7881","1437-210X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Synthesis","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108358331","display_name":"G\u00e9za St\u00e1jer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I227486990","display_name":"University of Szeged","ror":"https://ror.org/01pnej532","country_code":"HU","type":"education","lineage":["https://openalex.org/I227486990"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"G\u00e9za St\u00e1jer","raw_affiliation_strings":["Institute of Pharmaceutical Chemistry, University Medical School, H-6720 Szeged, E\u00f6tv\u00f6s u. 6, Hungary","University of Szeged"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Pharmaceutical Chemistry, University Medical School, H-6720 Szeged, E\u00f6tv\u00f6s u. 6, Hungary","institution_ids":["https://openalex.org/I227486990"]},{"raw_affiliation_string":"University of Szeged","institution_ids":["https://openalex.org/I227486990"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100880327","display_name":"Angela E. Szab\u00f3","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I227486990","display_name":"University of Szeged","ror":"https://ror.org/01pnej532","country_code":"HU","type":"education","lineage":["https://openalex.org/I227486990"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Angela E. Szab\u00f3","raw_affiliation_strings":["Institute of Pharmaceutical Chemistry, University Medical School, H-6720 Szeged, E\u00f6tv\u00f6s u. 6, Hungary","University of Szeged"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Pharmaceutical Chemistry, University Medical School, H-6720 Szeged, E\u00f6tv\u00f6s u. 6, Hungary","institution_ids":["https://openalex.org/I227486990"]},{"raw_affiliation_string":"University of Szeged","institution_ids":["https://openalex.org/I227486990"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111633558","display_name":"Gabor Bernath","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I227486990","display_name":"University of Szeged","ror":"https://ror.org/01pnej532","country_code":"HU","type":"education","lineage":["https://openalex.org/I227486990"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"G\u00e1bor Bern\u00e1th","raw_affiliation_strings":["Institute of Pharmaceutical Chemistry, University Medical School, H-6720 Szeged, E\u00f6tv\u00f6s u. 6, Hungary","University of Szeged"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Pharmaceutical Chemistry, University Medical School, H-6720 Szeged, E\u00f6tv\u00f6s u. 6, Hungary","institution_ids":["https://openalex.org/I227486990"]},{"raw_affiliation_string":"University of Szeged","institution_ids":["https://openalex.org/I227486990"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5001542128","display_name":"P\u00e0l Soh\u00e1r","orcid":"https://orcid.org/0000-0001-7302-5311","observed_orcids":["https://orcid.org/0000-0001-7302-5311"]},"institutions":[{"id":"https://openalex.org/I106118109","display_name":"E\u00f6tv\u00f6s Lor\u00e1nd University","ror":"https://ror.org/01jsq2704","country_code":"HU","type":"education","lineage":["https://openalex.org/I106118109"]},{"id":"https://openalex.org/I227486990","display_name":"University of Szeged","ror":"https://ror.org/01pnej532","country_code":"HU","type":"education","lineage":["https://openalex.org/I227486990"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"P\u00e1l Soh\u00e1r","raw_affiliation_strings":["Institute of Pharmaceutical Chemistry, University Medical School, H-6720 Szeged, E\u00f6tv\u00f6s u. 6, Hungary","E\u00f6tv\u00f6s Lorand University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Pharmaceutical Chemistry, University Medical School, H-6720 Szeged, E\u00f6tv\u00f6s u. 6, Hungary","institution_ids":["https://openalex.org/I227486990"]},{"raw_affiliation_string":"E\u00f6tv\u00f6s Lorand University","institution_ids":["https://openalex.org/I106118109"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.6079,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.75131003,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"1987","issue":"03","first_page":"290","last_page":"292"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13208","display_name":"Synthesis of heterocyclic compounds","score":0.8187999725341797,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13208","display_name":"Synthesis of heterocyclic compounds","score":0.8187999725341797,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13876","display_name":"Chemical synthesis and pharmacological studies","score":0.04800000041723251,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13649","display_name":"Advanced Synthetic Organic Chemistry","score":0.023000000044703484,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/retro-diels-alder-reaction","display_name":"retro-Diels-Alder reaction","score":0.9890000224113464},{"id":"https://openalex.org/keywords/ring-expansion","display_name":"ring expansion","score":0.8840000033378601},{"id":"https://openalex.org/keywords/one-pot-synthesis","display_name":"one-pot synthesis","score":0.7990000247955322},{"id":"https://openalex.org/keywords/pyrimidine-biosynthesis","display_name":"pyrimidine synthesis","score":0.609000027179718}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9822706580162048},{"id":"https://openalex.org/C2778176622","wikidata":"https://www.wikidata.org/wiki/Q424390","display_name":"Cyclopentadiene","level":3,"score":0.9366605281829834},{"id":"https://openalex.org/C2776041390","wikidata":"https://www.wikidata.org/wiki/Q407768","display_name":"Chlorobenzene","level":3,"score":0.8111813068389893},{"id":"https://openalex.org/C134121241","wikidata":"https://www.wikidata.org/wiki/Q899301","display_name":"Yield (engineering)","level":2,"score":0.7429467439651489},{"id":"https://openalex.org/C2779940776","wikidata":"https://www.wikidata.org/wiki/Q375669","display_name":"Diels\u2013Alder reaction","level":3,"score":0.5755875110626221},{"id":"https://openalex.org/C2780378348","wikidata":"https://www.wikidata.org/wiki/Q25351438","display_name":"Ring (chemistry)","level":2,"score":0.5386521816253662},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.5231997966766357},{"id":"https://openalex.org/C2780263894","wikidata":"https://www.wikidata.org/wiki/Q335268","display_name":"Alkyl","level":2,"score":0.4488617479801178},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.4335657060146332},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.22028377652168274},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1055/s-1987-27922","doi":"https://doi.org/10.1055/s-1987-27922","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-1987-27922","pdf_url":null,"source":{"id":"https://openalex.org/S197964166","display_name":"Synthesis","issn_l":"0039-7881","issn":["0039-7881","1437-210X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Synthesis","raw_type":"journal-article"},{"id":"pmh:oai:publicatio.bibl.u-szeged.hu:33020","doi":null,"is_oa":false,"landing_page_url":"http://publicatio.bibl.u-szeged.hu/33020/1/aok_klny_1010_87.pdf","pdf_url":"http://publicatio.bibl.u-szeged.hu/33020/1/aok_klny_1010_87.pdf","source":{"id":"https://openalex.org/S4306400675","display_name":"SZTE Publicatio Repozit\u00f3rium (University of Szeged)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I227486990","host_organization_name":"University of Szeged","host_organization_lineage":["https://openalex.org/I227486990"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Foly\u00f3iratcikk"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4242101238","https://openalex.org/W2119928472","https://openalex.org/W2950772056","https://openalex.org/W2113363346","https://openalex.org/W2587357157","https://openalex.org/W2950067378","https://openalex.org/W4415753095","https://openalex.org/W2981612084","https://openalex.org/W2952820653","https://openalex.org/W2050204171"],"abstract_inverted_index":{"All":[0],"articles":[1],"of":[2,71],"this":[3],"category":[4],"diexo":[5],"-3-Aza-4-oxotricyclo[4.2.1.0":[6],"2,5":[7],"]non-7-ene":[8],"(":[9],"1":[10,61],")":[11],"reacted":[12],"with":[13],"carboximidic":[14],"esters":[15],"by":[16],"ring":[17],"expansion":[18],"to":[19,38],"yield":[20],"tricyclic":[21],"5,6-dihydropyrimidin-4(3":[22],"H":[23,45],")-ones":[24,46],"3":[25],";":[26],"when":[27],"the":[28,69],"latter":[29],"were":[30],"refluxed":[31],"in":[32,56],"chlorobenzene":[33],"solution,":[34],"cyclopentadiene":[35],"split":[36],"off":[37],"give":[39],"2-alkyl,":[40],"2-aralkyl-,":[41],"2-cycloalkyl":[42],"and":[43],"2-arylpyrimidin-4(3":[44],"4a-h":[47],".":[48,74],"This":[49],"method,":[50],"which":[51],"is":[52],"conveniently":[53],"carried":[54],"out":[55],"a":[57,64],"\"one-pot\"":[58],"reaction":[59],"from":[60],",":[62],"provides":[63],"good":[65],"alternative":[66],"pathway":[67],"for":[68],"preparation":[70],"compounds":[72],"4":[73]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}