{"id":"https://openalex.org/W2050997486","doi":"https://doi.org/10.1155/2013/967581","title":"JC Polyomavirus (JCV) and Monoclonal Antibodies: Friends or Potential Foes?","display_name":"JC Polyomavirus (JCV) and Monoclonal Antibodies: Friends or Potential Foes?","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2050997486","doi":"https://doi.org/10.1155/2013/967581","mag":"2050997486","pmid":"https://pubmed.ncbi.nlm.nih.gov/23878587","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3708391"},"language":"en","primary_location":{"id":"doi:10.1155/2013/967581","doi":"https://doi.org/10.1155/2013/967581","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2013/967581","pdf_url":"https://downloads.hindawi.com/journals/jir/2013/967581.pdf","source":{"id":"https://openalex.org/S201433933","display_name":"Clinical and Developmental Immunology","issn_l":"1740-2522","issn":["1740-2522","1740-2530"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Developmental Immunology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://downloads.hindawi.com/journals/jir/2013/967581.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057292276","display_name":"Roberta A. Diotti","orcid":"https://orcid.org/0000-0002-7853-3224","observed_orcids":["https://orcid.org/0000-0002-7853-3224"]},"institutions":[{"id":"https://openalex.org/I154387261","display_name":"Vita-Salute San Raffaele University","ror":"https://ror.org/01gmqr298","country_code":"IT","type":"education","lineage":["https://openalex.org/I154387261"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Roberta Antonia Diotti","raw_affiliation_strings":["Microbiology and Virology Institute, Vita-Salute San Raffaele University, Via Olgettina 58, 20132 Milan, Italy"],"raw_orcid":"https://orcid.org/0000-0002-7853-3224","affiliations":[{"raw_affiliation_string":"Microbiology and Virology Institute, Vita-Salute San Raffaele University, Via Olgettina 58, 20132 Milan, Italy","institution_ids":["https://openalex.org/I154387261"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101801607","display_name":"Akira Nakanishi","orcid":"https://orcid.org/0000-0002-7702-9165","observed_orcids":["https://orcid.org/0000-0002-7702-9165"]},"institutions":[{"id":"https://openalex.org/I4210160102","display_name":"National Center for Geriatrics and Gerontology","ror":"https://ror.org/05h0rw812","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210160102"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akira Nakanishi","raw_affiliation_strings":["Department of Aging Intervention, National Center for Geriatrics and Gerontology, 35 Gengo, Morioka, Obu, Aichi 474-8522, Japan"],"raw_orcid":"https://orcid.org/0000-0002-7702-9165","affiliations":[{"raw_affiliation_string":"Department of Aging Intervention, National Center for Geriatrics and Gerontology, 35 Gengo, Morioka, Obu, Aichi 474-8522, Japan","institution_ids":["https://openalex.org/I4210160102"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008282651","display_name":"Nicola Clementi","orcid":"https://orcid.org/0000-0002-1822-9861","observed_orcids":["https://orcid.org/0000-0002-1822-9861"]},"institutions":[{"id":"https://openalex.org/I154387261","display_name":"Vita-Salute San Raffaele University","ror":"https://ror.org/01gmqr298","country_code":"IT","type":"education","lineage":["https://openalex.org/I154387261"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Nicola Clementi","raw_affiliation_strings":["Microbiology and Virology Institute, Vita-Salute San Raffaele University, Via Olgettina 58, 20132 Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology and Virology Institute, Vita-Salute San Raffaele University, Via Olgettina 58, 20132 Milan, Italy","institution_ids":["https://openalex.org/I154387261"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029436501","display_name":"Nicasio Mancini","orcid":"https://orcid.org/0000-0003-0637-0910","observed_orcids":["https://orcid.org/0000-0003-0637-0910"]},"institutions":[{"id":"https://openalex.org/I154387261","display_name":"Vita-Salute San Raffaele University","ror":"https://ror.org/01gmqr298","country_code":"IT","type":"education","lineage":["https://openalex.org/I154387261"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Nicasio Mancini","raw_affiliation_strings":["Microbiology and Virology Institute, Vita-Salute San Raffaele University, Via Olgettina 58, 20132 Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology and Virology Institute, Vita-Salute San Raffaele University, Via Olgettina 58, 20132 Milan, Italy","institution_ids":["https://openalex.org/I154387261"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060717808","display_name":"Elena Criscuolo","orcid":"https://orcid.org/0000-0003-0185-3147","observed_orcids":["https://orcid.org/0000-0003-0185-3147"]},"institutions":[{"id":"https://openalex.org/I154387261","display_name":"Vita-Salute San Raffaele University","ror":"https://ror.org/01gmqr298","country_code":"IT","type":"education","lineage":["https://openalex.org/I154387261"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Elena Criscuolo","raw_affiliation_strings":["Microbiology and Virology Institute, Vita-Salute San Raffaele University, Via Olgettina 58, 20132 Milan, Italy"],"raw_orcid":"https://orcid.org/0000-0003-0185-3147","affiliations":[{"raw_affiliation_string":"Microbiology and Virology Institute, Vita-Salute San Raffaele University, Via Olgettina 58, 20132 Milan, Italy","institution_ids":["https://openalex.org/I154387261"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055407583","display_name":"Laura Solforosi","orcid":"https://orcid.org/0000-0003-3786-6468","observed_orcids":["https://orcid.org/0000-0003-3786-6468"]},"institutions":[{"id":"https://openalex.org/I154387261","display_name":"Vita-Salute San Raffaele University","ror":"https://ror.org/01gmqr298","country_code":"IT","type":"education","lineage":["https://openalex.org/I154387261"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Laura Solforosi","raw_affiliation_strings":["Microbiology and Virology Institute, Vita-Salute San Raffaele University, Via Olgettina 58, 20132 Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology and Virology Institute, Vita-Salute San Raffaele University, Via Olgettina 58, 20132 Milan, Italy","institution_ids":["https://openalex.org/I154387261"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004847381","display_name":"Massimo Clementi","orcid":"https://orcid.org/0000-0002-7461-5898","observed_orcids":["https://orcid.org/0000-0002-7461-5898"]},"institutions":[{"id":"https://openalex.org/I154387261","display_name":"Vita-Salute San Raffaele University","ror":"https://ror.org/01gmqr298","country_code":"IT","type":"education","lineage":["https://openalex.org/I154387261"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Massimo Clementi","raw_affiliation_strings":["Microbiology and Virology Institute, Vita-Salute San Raffaele University, Via Olgettina 58, 20132 Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology and Virology Institute, Vita-Salute San Raffaele University, Via Olgettina 58, 20132 Milan, Italy","institution_ids":["https://openalex.org/I154387261"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5057292276"],"corresponding_institution_ids":["https://openalex.org/I154387261"],"apc_list":{"value":2100,"currency":"USD","value_usd":2100},"apc_paid":{"value":2100,"currency":"USD","value_usd":2100},"fwci":0.2821,"has_fulltext":true,"cited_by_count":18,"citation_normalized_percentile":{"value":0.29842244,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"2013","issue":null,"first_page":"1","last_page":"11"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11827","display_name":"Polyomavirus and related diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11827","display_name":"Polyomavirus and related diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10981","display_name":"Cytomegalovirus and herpesvirus research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/jc-virus","display_name":"JC virus","score":0.9559999704360962},{"id":"https://openalex.org/keywords/progressive-multifocal-leukoencephalopathy","display_name":"progressive multifocal leukoencephalopathy","score":0.9869999885559082},{"id":"https://openalex.org/keywords/natalizumab","display_name":"natalizumab","score":0.972000002861023},{"id":"https://openalex.org/keywords/multiple-sclerosis","display_name":"multiple sclerosis","score":0.8119999766349792},{"id":"https://openalex.org/keywords/monoclonal-antibodies","display_name":"monoclonal antibodies","score":0.9350000023841858},{"id":"https://openalex.org/keywords/immunodeficiency","display_name":"immunodeficiency","score":0.656000018119812},{"id":"https://openalex.org/keywords/hiv","display_name":"HIV","score":0.5559999942779541},{"id":"https://openalex.org/keywords/demyelinating-disorders","display_name":"demyelinating disease","score":0.7139999866485596}],"concepts":[{"id":"https://openalex.org/C2780644213","wikidata":"https://www.wikidata.org/wiki/Q704930","display_name":"Progressive multifocal leukoencephalopathy","level":3,"score":0.9835439920425415},{"id":"https://openalex.org/C2781004633","wikidata":"https://www.wikidata.org/wiki/Q386119","display_name":"Natalizumab","level":3,"score":0.9670311212539673},{"id":"https://openalex.org/C2779150272","wikidata":"https://www.wikidata.org/wiki/Q1676563","display_name":"JC virus","level":4,"score":0.8496568202972412},{"id":"https://openalex.org/C2780640218","wikidata":"https://www.wikidata.org/wiki/Q8277","display_name":"Multiple sclerosis","level":2,"score":0.7654417157173157},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5692304968833923},{"id":"https://openalex.org/C2778531937","wikidata":"https://www.wikidata.org/wiki/Q1186703","display_name":"Demyelinating disease","level":3,"score":0.5342212319374084},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5303540825843811},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.5090086460113525},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.49810338020324707},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4621146023273468},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.36230021715164185},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007107","descriptor_name":"Immune System","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007577","descriptor_name":"JC Virus","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007577","descriptor_name":"JC Virus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D007968","descriptor_name":"Leukoencephalopathy, Progressive Multifocal","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007968","descriptor_name":"Leukoencephalopathy, Progressive Multifocal","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D007968","descriptor_name":"Leukoencephalopathy, Progressive Multifocal","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1155/2013/967581","doi":"https://doi.org/10.1155/2013/967581","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2013/967581","pdf_url":"https://downloads.hindawi.com/journals/jir/2013/967581.pdf","source":{"id":"https://openalex.org/S201433933","display_name":"Clinical and Developmental Immunology","issn_l":"1740-2522","issn":["1740-2522","1740-2530"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Developmental Immunology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2711771","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3708391","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3708391","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3708391","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Dev Immunol","raw_type":"Text"},{"id":"pmid:23878587","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23878587","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical & developmental immunology","raw_type":"Journal Article"},{"id":"pmh:oai:iris.unisr.it:20.500.11768/10110","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/20.500.11768/10110","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1155/2013/967581","source":{"id":"https://openalex.org/S7407055348","display_name":"Archivio Istituzionale della Ricerca - Universit\u00e0 Vita-Salute San Raffaele","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:62b9d2fb08544ceaa152ca8321cf24db","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/62b9d2fb08544ceaa152ca8321cf24db","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Clinical and Developmental Immunology, Vol 2013 (2013)","raw_type":"article"},{"id":"pmh:oai:irinsubria.uninsubria.it:11383/2148979","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/11383/2148979","pdf_url":null,"source":{"id":"https://openalex.org/S4377196351","display_name":"IrInSubria (University of Insubria)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I115752224","host_organization_name":"University of Insubria","host_organization_lineage":["https://openalex.org/I115752224"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1155/2013/967581","doi":"https://doi.org/10.1155/2013/967581","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2013/967581","pdf_url":"https://downloads.hindawi.com/journals/jir/2013/967581.pdf","source":{"id":"https://openalex.org/S201433933","display_name":"Clinical and Developmental Immunology","issn_l":"1740-2522","issn":["1740-2522","1740-2530"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Developmental Immunology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2050997486.pdf","grobid_xml":"https://content.openalex.org/works/W2050997486.grobid-xml"},"referenced_works_count":115,"referenced_works":["https://openalex.org/W44613858","https://openalex.org/W1504746607","https://openalex.org/W1521994937","https://openalex.org/W1748131880","https://openalex.org/W1926153927","https://openalex.org/W1927377064","https://openalex.org/W1940558382","https://openalex.org/W1943449996","https://openalex.org/W1967031586","https://openalex.org/W1969355897","https://openalex.org/W1969743228","https://openalex.org/W1970908625","https://openalex.org/W1975116537","https://openalex.org/W1977119565","https://openalex.org/W1978021511","https://openalex.org/W1981039623","https://openalex.org/W1982614909","https://openalex.org/W1982947309","https://openalex.org/W1984107906","https://openalex.org/W1984587729","https://openalex.org/W1984815339","https://openalex.org/W1989209244","https://openalex.org/W1992080507","https://openalex.org/W1995606157","https://openalex.org/W1998013907","https://openalex.org/W2000388934","https://openalex.org/W2000402112","https://openalex.org/W2000534965","https://openalex.org/W2003575672","https://openalex.org/W2004646918","https://openalex.org/W2005259841","https://openalex.org/W2006311979","https://openalex.org/W2008732326","https://openalex.org/W2009329755","https://openalex.org/W2009857746","https://openalex.org/W2010643375","https://openalex.org/W2011942348","https://openalex.org/W2012150936","https://openalex.org/W2012991004","https://openalex.org/W2017914322","https://openalex.org/W2020670698","https://openalex.org/W2027675576","https://openalex.org/W2030868322","https://openalex.org/W2033099184","https://openalex.org/W2033891839","https://openalex.org/W2037298492","https://openalex.org/W2042885556","https://openalex.org/W2044022462","https://openalex.org/W2052652876","https://openalex.org/W2053133354","https://openalex.org/W2053807198","https://openalex.org/W2057652506","https://openalex.org/W2063092703","https://openalex.org/W2065306834","https://openalex.org/W2067521963","https://openalex.org/W2069407087","https://openalex.org/W2069416484","https://openalex.org/W2071633990","https://openalex.org/W2071917362","https://openalex.org/W2073551625","https://openalex.org/W2074645082","https://openalex.org/W2077106871","https://openalex.org/W2079594480","https://openalex.org/W2083345819","https://openalex.org/W2092350058","https://openalex.org/W2093775095","https://openalex.org/W2099046838","https://openalex.org/W2099647077","https://openalex.org/W2099709035","https://openalex.org/W2106370877","https://openalex.org/W2108718949","https://openalex.org/W2108930460","https://openalex.org/W2108996306","https://openalex.org/W2109517616","https://openalex.org/W2110134415","https://openalex.org/W2110638344","https://openalex.org/W2114360739","https://openalex.org/W2114792084","https://openalex.org/W2115673743","https://openalex.org/W2117852626","https://openalex.org/W2118913456","https://openalex.org/W2129626693","https://openalex.org/W2130307188","https://openalex.org/W2130730608","https://openalex.org/W2132108285","https://openalex.org/W2132351425","https://openalex.org/W2135008723","https://openalex.org/W2136390349","https://openalex.org/W2140463009","https://openalex.org/W2145068137","https://openalex.org/W2145197472","https://openalex.org/W2150676596","https://openalex.org/W2151320496","https://openalex.org/W2152504521","https://openalex.org/W2153559754","https://openalex.org/W2153686676","https://openalex.org/W2155590477","https://openalex.org/W2155620154","https://openalex.org/W2156392752","https://openalex.org/W2162671566","https://openalex.org/W2162965271","https://openalex.org/W2164788138","https://openalex.org/W2165229568","https://openalex.org/W2166730447","https://openalex.org/W2166953287","https://openalex.org/W2168339945","https://openalex.org/W2186135978","https://openalex.org/W2224780480","https://openalex.org/W2324009744","https://openalex.org/W2328526824","https://openalex.org/W2328735339","https://openalex.org/W2336267303","https://openalex.org/W2470916201","https://openalex.org/W2482394274","https://openalex.org/W3151482424"],"related_works":["https://openalex.org/W4411502021","https://openalex.org/W2798039679","https://openalex.org/W2087571718","https://openalex.org/W2524594667","https://openalex.org/W2061998346","https://openalex.org/W2525975783","https://openalex.org/W2796944870","https://openalex.org/W2412358677","https://openalex.org/W2314996545","https://openalex.org/W2141891977"],"abstract_inverted_index":{"Progressive":[0],"multifocal":[1],"leukoencephalopathy":[2],"(PML)":[3],"is":[4],"a":[5,51],"demyelinating":[6],"disease":[7],"of":[8,36,49,62,68,77,82,92,107,112],"the":[9,30,34,39,47,59,75,80,90,105,108],"central":[10],"nervous":[11],"system":[12],"(CNS),":[13],"observed":[14],"in":[15,54,70],"immunodeficient":[16],"patients":[17,72,88],"and":[18,33,58,89],"caused":[19],"by":[20],"JC":[21,26],"virus":[22],"((JCV),":[23],"also":[24],"called":[25],"polyomavirus":[27],"(JCPyV)).":[28],"After":[29],"HIV":[31],"pandemic":[32],"introduction":[35],"immunomodulatory":[37],"therapy,":[38],"PML":[40,60,69,83,113],"incidence":[41,67],"significantly":[42],"increased.":[43],"The":[44,65],"correlation":[45],"between":[46],"use":[48],"natalizumab,":[50],"drug":[52],"used":[53],"multiple":[55],"sclerosis":[56],"(MS),":[57],"development":[61],"particular":[63],"relevance.":[64],"high":[66],"natalizumab-treated":[71,87],"has":[73],"highlighted":[74],"importance":[76],"two":[78,102],"factors:":[79],"need":[81,91],"risk":[84],"stratification":[85],"among":[86],"effective":[93],"therapeutic":[94],"options.":[95],"In":[96],"this":[97],"review,":[98],"we":[99],"discuss":[100],"these":[101],"needs":[103],"under":[104],"light":[106],"major":[109],"viral":[110],"models":[111],"etiopathogenesis.":[114]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}