{"id":"https://openalex.org/W2050896830","doi":"https://doi.org/10.1080/00914037.2014.977900","title":"Dose-Dependent Effects of Gamma Irradiation on the Materials Properties and Cell Proliferation of Electrospun Polycaprolactone Tissue Engineering Scaffolds","display_name":"Dose-Dependent Effects of Gamma Irradiation on the Materials Properties and Cell Proliferation of Electrospun Polycaprolactone Tissue Engineering Scaffolds","publication_year":2015,"publication_date":"2015-01-13","ids":{"openalex":"https://openalex.org/W2050896830","doi":"https://doi.org/10.1080/00914037.2014.977900","mag":"2050896830"},"language":"en","primary_location":{"id":"doi:10.1080/00914037.2014.977900","doi":"https://doi.org/10.1080/00914037.2014.977900","is_oa":false,"landing_page_url":"https://doi.org/10.1080/00914037.2014.977900","pdf_url":null,"source":{"id":"https://openalex.org/S176437474","display_name":"International Journal of Polymeric Materials","issn_l":"0091-4037","issn":["0091-4037","1026-7751","1563-535X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Polymeric Materials and Polymeric Biomaterials","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058180864","display_name":"Robin Augustine","orcid":"https://orcid.org/0000-0001-9724-8392","observed_orcids":["https://orcid.org/0000-0001-9724-8392"]},"institutions":[{"id":"https://openalex.org/I177436651","display_name":"Mahatma Gandhi University","ror":"https://ror.org/00h4spn88","country_code":"IN","type":"education","lineage":["https://openalex.org/I177436651"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Robin Augustine","raw_affiliation_strings":["International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala, India","institution_ids":["https://openalex.org/I177436651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113612529","display_name":"Abhijit Saha","orcid":"https://orcid.org/0000-0002-1275-8420","observed_orcids":["https://orcid.org/0000-0002-1275-8420"]},"institutions":[{"id":"https://openalex.org/I4210132317","display_name":"UGC DAE Consortium for Scientific Research","ror":"https://ror.org/047g7f905","country_code":"IN","type":"other","lineage":["https://openalex.org/I4210132317"]},{"id":"https://openalex.org/I4402554027","display_name":"UGC-DAE Consortium for Scientific Research, Kolkata Centre","ror":"https://ror.org/02c0fsq39","country_code":"IN","type":"government","lineage":["https://openalex.org/I4402554027"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Abhijit Saha","raw_affiliation_strings":["UGC-DAE Consortium for Scientific Research, Kolkata, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UGC-DAE Consortium for Scientific Research, Kolkata, India","institution_ids":["https://openalex.org/I4210132317","https://openalex.org/I4402554027"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107881906","display_name":"V.P. Jayachandran","orcid":"https://orcid.org/0000-0002-7249-1422","observed_orcids":["https://orcid.org/0000-0002-7249-1422"]},"institutions":[{"id":"https://openalex.org/I2802498779","display_name":"Pushpagiri Medical College","ror":"https://ror.org/02f7s4h98","country_code":"IN","type":"education","lineage":["https://openalex.org/I2802498779"]},{"id":"https://openalex.org/I69552723","display_name":"University of Pretoria","ror":"https://ror.org/00g0p6g84","country_code":"ZA","type":"education","lineage":["https://openalex.org/I69552723"]}],"countries":["IN","ZA"],"is_corresponding":false,"raw_author_name":"V. P. Jayachandran","raw_affiliation_strings":["Department of Food Science, University of Pretoria, Hatfield, Pretoria, South Africa; Antibacterials and Microbial Technology Lab, Pushpagiri Research Centre, Pushpagiri Institute of Medical Sciences, Tiruvalla, Kerala, India","Antibacterials and Microbial Technology Lab, Pushpagiri Research Centre, Pushpagiri Institute of Medical Sciences, Tiruvalla, Kerala, India","Department of Food Science, University of Pretoria, Hatfield, Pretoria, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Food Science, University of Pretoria, Hatfield, Pretoria, South Africa; Antibacterials and Microbial Technology Lab, Pushpagiri Research Centre, Pushpagiri Institute of Medical Sciences, Tiruvalla, Kerala, India","institution_ids":["https://openalex.org/I2802498779","https://openalex.org/I69552723"]},{"raw_affiliation_string":"Antibacterials and Microbial Technology Lab, Pushpagiri Research Centre, Pushpagiri Institute of Medical Sciences, Tiruvalla, Kerala, India","institution_ids":["https://openalex.org/I2802498779"]},{"raw_affiliation_string":"Department of Food Science, University of Pretoria, Hatfield, Pretoria, South Africa","institution_ids":["https://openalex.org/I69552723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107944136","display_name":"Sabu Thomas","orcid":"https://orcid.org/0000-0003-4726-5746","observed_orcids":["https://orcid.org/0000-0003-4726-5746"]},"institutions":[{"id":"https://openalex.org/I177436651","display_name":"Mahatma Gandhi University","ror":"https://ror.org/00h4spn88","country_code":"IN","type":"education","lineage":["https://openalex.org/I177436651"]},{"id":"https://openalex.org/I4405260745","display_name":"Mahatma Gandhi University","ror":"https://ror.org/04702m080","country_code":"IN","type":"education","lineage":["https://openalex.org/I4405260745"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Sabu Thomas","raw_affiliation_strings":["International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala, India; School of Chemical Sciences, Mahatma Gandhi University, Kottayam, Kerala, India","International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala, India","School of Chemical Sciences, Mahatma Gandhi University, Kottayam, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala, India; School of Chemical Sciences, Mahatma Gandhi University, Kottayam, Kerala, India","institution_ids":["https://openalex.org/I177436651","https://openalex.org/I4405260745"]},{"raw_affiliation_string":"International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala, India","institution_ids":["https://openalex.org/I177436651"]},{"raw_affiliation_string":"School of Chemical Sciences, Mahatma Gandhi University, Kottayam, Kerala, India","institution_ids":["https://openalex.org/I177436651"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064125049","display_name":"Nandakumar Kalarikkal","orcid":"https://orcid.org/0000-0002-4595-6466","observed_orcids":["https://orcid.org/0000-0002-4595-6466","https://orcid.org/0000-0003-0795-9284","https://orcid.org/0000-0001-5525-4081","https://orcid.org/0000-0002-9731-8255"]},"institutions":[{"id":"https://openalex.org/I177436651","display_name":"Mahatma Gandhi University","ror":"https://ror.org/00h4spn88","country_code":"IN","type":"education","lineage":["https://openalex.org/I177436651"]},{"id":"https://openalex.org/I4405260745","display_name":"Mahatma Gandhi University","ror":"https://ror.org/04702m080","country_code":"IN","type":"education","lineage":["https://openalex.org/I4405260745"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Nandakumar Kalarikkal","raw_affiliation_strings":["International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala, India; School of Pure and Applied Physics, Mahatma Gandhi University, Kottayam, Kerala, India","International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala, India","School of Pure and Applied Physics, Mahatma Gandhi University, Kottayam, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala, India; School of Pure and Applied Physics, Mahatma Gandhi University, Kottayam, Kerala, India","institution_ids":["https://openalex.org/I177436651","https://openalex.org/I4405260745"]},{"raw_affiliation_string":"International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala, India","institution_ids":["https://openalex.org/I177436651"]},{"raw_affiliation_string":"School of Pure and Applied Physics, Mahatma Gandhi University, Kottayam, Kerala, India","institution_ids":["https://openalex.org/I177436651"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5064125049","https://openalex.org/A5107944136"],"corresponding_institution_ids":["https://openalex.org/I177436651","https://openalex.org/I4405260745"],"apc_list":null,"apc_paid":null,"fwci":1.7834,"has_fulltext":false,"cited_by_count":76,"citation_normalized_percentile":{"value":0.82116893,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"64","issue":"10","first_page":"526","last_page":"533"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.9818999767303467,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.9818999767303467,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11966","display_name":"Silk-based biomaterials and applications","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polycaprolactone","display_name":"polycaprolactone","score":0.9309999942779541},{"id":"https://openalex.org/keywords/gamma-irradiation","display_name":"gamma irradiation","score":0.8009999990463257},{"id":"https://openalex.org/keywords/sterilization","display_name":"sterilization","score":0.7639999985694885},{"id":"https://openalex.org/keywords/electrospun-membranes","display_name":"electrospun membranes","score":0.859000027179718},{"id":"https://openalex.org/keywords/tissue-engineering-scaffolds","display_name":"tissue engineering scaffolds","score":0.996999979019165},{"id":"https://openalex.org/keywords/radiation-dose-dependence","display_name":"radiation dose dependence","score":0.6869999766349792},{"id":"https://openalex.org/keywords/crystallinity","display_name":"crystallinity","score":0.9300000071525574},{"id":"https://openalex.org/keywords/surface-degradation","display_name":"surface degradation","score":0.8270000219345093},{"id":"https://openalex.org/keywords/hydrophilicity","display_name":"hydrophilicity","score":0.9670000076293945},{"id":"https://openalex.org/keywords/mechanical-properties","display_name":"mechanical properties","score":0.9950000047683716},{"id":"https://openalex.org/keywords/fibroblast-proliferation","display_name":"fibroblast proliferation","score":0.8629999756813049},{"id":"https://openalex.org/keywords/sterility","display_name":"sterility","score":0.7020000219345093}],"concepts":[{"id":"https://openalex.org/C2779868350","wikidata":"https://www.wikidata.org/wiki/Q109674","display_name":"Polycaprolactone","level":3,"score":0.9691556692123413},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.6258026361465454},{"id":"https://openalex.org/C46275449","wikidata":"https://www.wikidata.org/wiki/Q2458815","display_name":"Crystallinity","level":2,"score":0.6246451139450073},{"id":"https://openalex.org/C111337013","wikidata":"https://www.wikidata.org/wiki/Q2737837","display_name":"Irradiation","level":2,"score":0.5862057209014893},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5796530246734619},{"id":"https://openalex.org/C3017806408","wikidata":"https://www.wikidata.org/wiki/Q92772955","display_name":"Gamma irradiation","level":3,"score":0.5725145936012268},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.5196353197097778},{"id":"https://openalex.org/C144796933","wikidata":"https://www.wikidata.org/wiki/Q1533542","display_name":"Electrospinning","level":3,"score":0.45834824442863464},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.4489455223083496},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3107990026473999},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.21072188019752502},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.08455976843833923},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.05415850877761841},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C185544564","wikidata":"https://www.wikidata.org/wiki/Q81197","display_name":"Nuclear physics","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1080/00914037.2014.977900","doi":"https://doi.org/10.1080/00914037.2014.977900","is_oa":false,"landing_page_url":"https://doi.org/10.1080/00914037.2014.977900","pdf_url":null,"source":{"id":"https://openalex.org/S176437474","display_name":"International Journal of Polymeric Materials","issn_l":"0091-4037","issn":["0091-4037","1026-7751","1563-535X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Polymeric Materials and Polymeric Biomaterials","raw_type":"journal-article"},{"id":"pmh:oai:repository.up.ac.za:2263/44190","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2263/44190","pdf_url":null,"source":{"id":"https://openalex.org/S4306401870","display_name":"UpSpace Institutional Repository (University of Pretoria)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I69552723","host_organization_name":"University of Pretoria","host_organization_lineage":["https://openalex.org/I69552723"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Postprint Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.7246000170707703,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320717","display_name":"Department of Biotechnology, Ministry of Science and Technology, India","ror":"https://ror.org/03tjsyq23"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W114143726","https://openalex.org/W1524095564","https://openalex.org/W1584703657","https://openalex.org/W1588306027","https://openalex.org/W1966363916","https://openalex.org/W1967598259","https://openalex.org/W1977118682","https://openalex.org/W1980144664","https://openalex.org/W1986666896","https://openalex.org/W1987835396","https://openalex.org/W1991179459","https://openalex.org/W1991954267","https://openalex.org/W2010895314","https://openalex.org/W2011126645","https://openalex.org/W2014610385","https://openalex.org/W2022101463","https://openalex.org/W2026946890","https://openalex.org/W2030795397","https://openalex.org/W2032275376","https://openalex.org/W2032876641","https://openalex.org/W2058929750","https://openalex.org/W2079586645","https://openalex.org/W2079849620","https://openalex.org/W2082032900","https://openalex.org/W2082478053","https://openalex.org/W2086085687","https://openalex.org/W2095752286","https://openalex.org/W2127318571","https://openalex.org/W2129351745","https://openalex.org/W2133679632","https://openalex.org/W2171314179","https://openalex.org/W2278657244","https://openalex.org/W4255454916"],"related_works":["https://openalex.org/W2032876641","https://openalex.org/W2923638025","https://openalex.org/W3015801809","https://openalex.org/W4414014694","https://openalex.org/W2095752286","https://openalex.org/W2152821153","https://openalex.org/W4323021631","https://openalex.org/W4405179762","https://openalex.org/W2197658081","https://openalex.org/W2737501514"],"abstract_inverted_index":{"Electrospun":[0],"membranes":[1,44,97],"of":[2,41,48,89],"polycaprolactone":[3,43,77],"are":[4],"widely":[5],"used":[6],"for":[7,56],"biomedical":[8],"applications":[9],"such":[10],"as":[11],"wound":[12],"dressings":[13],"and":[14,68,101],"tissue":[15],"engineering":[16],"scaffolds.":[17],"It":[18],"is":[19],"important":[20],"to":[21],"sterilize":[22],"this":[23,34],"material":[24],"using":[25],"the":[26,30,36,39,57,69,92],"most":[27],"accepted":[28],"method,":[29],"gamma":[31,46,83],"irradiation.":[32],"In":[33],"study,":[35],"authors":[37],"evaluated":[38],"sterilizability":[40],"electrospun":[42,76],"with":[45],"radiation":[47,90],"varying":[49],"doses.":[50],"The":[51,72,95],"irradiated":[52,96],"materials":[53,93],"were":[54],"assessed":[55],"changes":[58],"in":[59],"morphology,":[60],"crystallinity,":[61],"surface":[62],"degradation,":[63],"hydrophilicity,":[64],"mechanical":[65],"property,":[66],"sterility,":[67],"cell":[70,103],"proliferation.":[71,104],"results":[73],"demonstrate":[74],"that":[75],"can":[78],"be":[79],"effectively":[80],"sterilized":[81],"by":[82],"irradiation,":[84],"however":[85],"a":[86],"higher":[87],"dose":[88],"affects":[91],"properties.":[94],"showed":[98],"improved":[99],"hydrophilicity":[100],"fibroblast":[102]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":12},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}