{"id":"https://openalex.org/W2050217161","doi":"https://doi.org/10.1038/sj.ejcn.1602102","title":"Effect of CLA supplementation on immune function in young healthy volunteers","display_name":"Effect of CLA supplementation on immune function in young healthy volunteers","publication_year":2005,"publication_date":"2005-01-12","ids":{"openalex":"https://openalex.org/W2050217161","doi":"https://doi.org/10.1038/sj.ejcn.1602102","mag":"2050217161","pmid":"https://pubmed.ncbi.nlm.nih.gov/15674307"},"language":"en","primary_location":{"id":"doi:10.1038/sj.ejcn.1602102","doi":"https://doi.org/10.1038/sj.ejcn.1602102","is_oa":false,"landing_page_url":"https://doi.org/10.1038/sj.ejcn.1602102","pdf_url":null,"source":{"id":"https://openalex.org/S126770807","display_name":"European Journal of Clinical Nutrition","issn_l":"0954-3007","issn":["0954-3007","1476-5640"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Clinical Nutrition","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100861549","display_name":"H-J Song","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I195460627","display_name":"University of Aberdeen","ror":"https://ror.org/016476m91","country_code":"GB","type":"education","lineage":["https://openalex.org/I195460627"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"H-J Song","raw_affiliation_strings":["Rowett Research Institute, Aberdeen, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rowett Research Institute, Aberdeen, UK","institution_ids":["https://openalex.org/I195460627"]}]},{"author_position":"middle","author":{"id":null,"display_name":"I Grant","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I522815984","display_name":"Robert Gordon University","ror":"https://ror.org/04f0qj703","country_code":"GB","type":"education","lineage":["https://openalex.org/I522815984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"I Grant","raw_affiliation_strings":["The Robert Gordon University, Aberdeen, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Robert Gordon University, Aberdeen, UK","institution_ids":["https://openalex.org/I522815984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017551007","display_name":"Davide Rotondo","orcid":"https://orcid.org/0009-0002-5605-8968","observed_orcids":["https://orcid.org/0009-0002-5605-8968"]},"institutions":[{"id":"https://openalex.org/I181647926","display_name":"University of Strathclyde","ror":"https://ror.org/00n3w3b69","country_code":"GB","type":"education","lineage":["https://openalex.org/I181647926"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"D Rotondo","raw_affiliation_strings":["Strathclyde University, Glasgow, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Strathclyde University, Glasgow, UK","institution_ids":["https://openalex.org/I181647926"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001934957","display_name":"Inge Mohede","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"I Mohede","raw_affiliation_strings":["Loders-Croklaan, Wormerveer, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Loders-Croklaan, Wormerveer, The Netherlands","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078498803","display_name":"Naveed A. Sattar","orcid":"https://orcid.org/0000-0002-1604-2593","observed_orcids":["https://orcid.org/0000-0002-1604-2593"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"N Sattar","raw_affiliation_strings":["Pathological Biochemistry, Glasgow University, Glasgow, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pathological Biochemistry, Glasgow University, Glasgow, UK","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109248213","display_name":"Steven D. Heys","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I195460627","display_name":"University of Aberdeen","ror":"https://ror.org/016476m91","country_code":"GB","type":"education","lineage":["https://openalex.org/I195460627"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S D Heys","raw_affiliation_strings":["Surgical & Nutritional Oncology, Medical School, Aberdeen University, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Surgical & Nutritional Oncology, Medical School, Aberdeen University, UK","institution_ids":["https://openalex.org/I195460627"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047323069","display_name":"Klaus W.J. Wahle","orcid":"https://orcid.org/0000-0002-2811-7150","observed_orcids":["https://orcid.org/0000-0002-2811-7150"]},"institutions":[{"id":"https://openalex.org/I195460627","display_name":"University of Aberdeen","ror":"https://ror.org/016476m91","country_code":"GB","type":"education","lineage":["https://openalex.org/I195460627"]},{"id":"https://openalex.org/I522815984","display_name":"Robert Gordon University","ror":"https://ror.org/04f0qj703","country_code":"GB","type":"education","lineage":["https://openalex.org/I522815984"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"K W J Wahle","raw_affiliation_strings":["Rowett Research Institute, Aberdeen, UK","The Robert Gordon University, Aberdeen, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rowett Research Institute, Aberdeen, UK","institution_ids":["https://openalex.org/I195460627"]},{"raw_affiliation_string":"The Robert Gordon University, Aberdeen, UK","institution_ids":["https://openalex.org/I522815984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5047323069"],"corresponding_institution_ids":["https://openalex.org/I195460627","https://openalex.org/I522815984"],"apc_list":{"value":3590,"currency":"USD","value_usd":3590},"apc_paid":null,"fwci":8.2957,"has_fulltext":false,"cited_by_count":163,"citation_normalized_percentile":{"value":0.97866278,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"59","issue":"4","first_page":"508","last_page":"517"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10909","display_name":"Edible Oils Quality and Analysis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/conjugated-linoleic-acid","display_name":"conjugated linoleic acid","score":0.9760000109672546},{"id":"https://openalex.org/keywords/dietary-supplementation","display_name":"dietary supplementation","score":0.8640000224113464},{"id":"https://openalex.org/keywords/immune-function","display_name":"immune function","score":0.9940000176429749},{"id":"https://openalex.org/keywords/plasma-immunoglobulins","display_name":"plasma immunoglobulins","score":0.7630000114440918},{"id":"https://openalex.org/keywords/iga","display_name":"IgA","score":0.8650000095367432},{"id":"https://openalex.org/keywords/igm","display_name":"IgM","score":0.9869999885559082},{"id":"https://openalex.org/keywords/ige","display_name":"IgE","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.7879999876022339},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9390000104904175},{"id":"https://openalex.org/keywords/interleukin-1beta","display_name":"IL-1\u03b2","score":0.9049999713897705},{"id":"https://openalex.org/keywords/il-10","display_name":"IL-10","score":1.0},{"id":"https://openalex.org/keywords/delayed-type-hypersensitivity","display_name":"delayed-type hypersensitivity","score":0.9599999785423279},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.7099999785423279},{"id":"https://openalex.org/keywords/anti-inflammatory-cytokines","display_name":"anti-inflammatory cytokines","score":0.8180000185966492},{"id":"https://openalex.org/keywords/plasma-lipids","display_name":"plasma lipids","score":0.7459999918937683},{"id":"https://openalex.org/keywords/plasma-glucose","display_name":"plasma glucose","score":0.9449999928474426},{"id":"https://openalex.org/keywords/lymphocyte-phenotype","display_name":"lymphocyte phenotype","score":0.7250000238418579},{"id":"https://openalex.org/keywords/healthy-young-adults","display_name":"healthy young adults","score":0.5759999752044678}],"concepts":[{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6956288814544678},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.583653450012207},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5666771531105042},{"id":"https://openalex.org/C164027704","wikidata":"https://www.wikidata.org/wiki/Q3491837","display_name":"Proinflammatory cytokine","level":3,"score":0.5603116154670715},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5253041386604309},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5030638575553894},{"id":"https://openalex.org/C2780556605","wikidata":"https://www.wikidata.org/wiki/Q94787","display_name":"Sunflower oil","level":2,"score":0.47991642355918884},{"id":"https://openalex.org/C2779946292","wikidata":"https://www.wikidata.org/wiki/Q1786125","display_name":"Fish oil","level":3,"score":0.4390186369419098},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.30292588472366333},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2816895842552185},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.2528522312641144},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.24186202883720398},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.23851487040519714},{"id":"https://openalex.org/C2909208804","wikidata":"https://www.wikidata.org/wiki/Q127282","display_name":"Fish <Actinopterygii>","level":2,"score":0.0},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002097","descriptor_name":"C-Reactive Protein","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006968","descriptor_name":"Hypersensitivity, Delayed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007109","descriptor_name":"Immunity","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D007109","descriptor_name":"Immunity","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D007136","descriptor_name":"Immunoglobulins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007136","descriptor_name":"Immunoglobulins","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012016","descriptor_name":"Reference Values","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D019587","descriptor_name":"Dietary Supplements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D044243","descriptor_name":"Linoleic Acids, Conjugated","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1038/sj.ejcn.1602102","doi":"https://doi.org/10.1038/sj.ejcn.1602102","is_oa":false,"landing_page_url":"https://doi.org/10.1038/sj.ejcn.1602102","pdf_url":null,"source":{"id":"https://openalex.org/S126770807","display_name":"European Journal of Clinical Nutrition","issn_l":"0954-3007","issn":["0954-3007","1476-5640"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Clinical Nutrition","raw_type":"journal-article"},{"id":"pmid:15674307","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15674307","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of clinical nutrition","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W83643349","https://openalex.org/W300755610","https://openalex.org/W1699935698","https://openalex.org/W1874810612","https://openalex.org/W1961468023","https://openalex.org/W1964694178","https://openalex.org/W1966544243","https://openalex.org/W1969261586","https://openalex.org/W1995329097","https://openalex.org/W2001491599","https://openalex.org/W2004306309","https://openalex.org/W2021978753","https://openalex.org/W2031264457","https://openalex.org/W2040262168","https://openalex.org/W2047389118","https://openalex.org/W2049500405","https://openalex.org/W2054539209","https://openalex.org/W2058240826","https://openalex.org/W2085974388","https://openalex.org/W2089451891","https://openalex.org/W2092346211","https://openalex.org/W2098915204","https://openalex.org/W2105912552","https://openalex.org/W2106592114","https://openalex.org/W2108106611","https://openalex.org/W2141751852","https://openalex.org/W2163501355","https://openalex.org/W2164592152","https://openalex.org/W2169121622","https://openalex.org/W2327470041","https://openalex.org/W2417754689","https://openalex.org/W2518887838","https://openalex.org/W2607412715","https://openalex.org/W4238186278","https://openalex.org/W4285081295"],"related_works":["https://openalex.org/W2072330362","https://openalex.org/W2092346211","https://openalex.org/W2098915204","https://openalex.org/W2070117324","https://openalex.org/W2166869605","https://openalex.org/W414838655","https://openalex.org/W2980766522","https://openalex.org/W2156038584","https://openalex.org/W2161231727","https://openalex.org/W3176734808"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":13},{"year":2012,"cited_by_count":10}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}