{"id":"https://openalex.org/W2050156447","doi":"https://doi.org/10.1562/0031-8655(2004)080<0471:hsolsc>2.0.co;2","title":"High-resolution Studies of Lung Surfactant Collapse\u00b6","display_name":"High-resolution Studies of Lung Surfactant Collapse\u00b6","publication_year":2004,"publication_date":"2004-01-01","ids":{"openalex":"https://openalex.org/W2050156447","doi":"https://doi.org/10.1562/0031-8655(2004)080<0471:hsolsc>2.0.co;2","mag":"2050156447","pmid":"https://pubmed.ncbi.nlm.nih.gov/15623332"},"language":"en","primary_location":{"id":"doi:10.1562/0031-8655(2004)080<0471:hsolsc>2.0.co;2","doi":"https://doi.org/10.1562/0031-8655(2004)080<0471:hsolsc>2.0.co;2","is_oa":false,"landing_page_url":"https://doi.org/10.1562/0031-8655(2004)080<0471:hsolsc>2.0.co;2","pdf_url":null,"source":{"id":"https://openalex.org/S61245073","display_name":"Photochemistry and Photobiology","issn_l":"0031-8655","issn":["0031-8655","1751-1097"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Photochemistry and Photobiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006645328","display_name":"Rachel Sibug-Aga","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146416000","display_name":"University of Kansas","ror":"https://ror.org/001tmjg57","country_code":"US","type":"education","lineage":["https://openalex.org/I146416000"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rachel Sibug-Aga","raw_affiliation_strings":["Department of Chemistry, University of Kansas, Lawrence, KS 66045, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Kansas, Lawrence, KS 66045, USA","institution_ids":["https://openalex.org/I146416000"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049665897","display_name":"Robert C. Dunn","orcid":"https://orcid.org/0000-0002-6632-9736","observed_orcids":["https://orcid.org/0000-0002-6632-9736"]},"institutions":[{"id":"https://openalex.org/I146416000","display_name":"University of Kansas","ror":"https://ror.org/001tmjg57","country_code":"US","type":"education","lineage":["https://openalex.org/I146416000"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Robert C. Dunn","raw_affiliation_strings":["Department of Chemistry, University of Kansas, Lawrence, KS","Department of Chemistry, University of Kansas, Lawrence, KS#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Kansas, Lawrence, KS","institution_ids":["https://openalex.org/I146416000"]},{"raw_affiliation_string":"Department of Chemistry, University of Kansas, Lawrence, KS#TAB#","institution_ids":["https://openalex.org/I146416000"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5049665897"],"corresponding_institution_ids":["https://openalex.org/I146416000"],"apc_list":{"value":4330,"currency":"USD","value_usd":4330},"apc_paid":null,"fwci":0.2367,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.50884019,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"80","issue":"3","first_page":"471","last_page":"471"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.5800999999046326,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.5800999999046326,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.33570000529289246,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10721","display_name":"Surfactants and Colloidal Systems","score":0.06469999998807907,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pulmonary-surfactant","display_name":"pulmonary surfactant","score":0.9760000109672546},{"id":"https://openalex.org/keywords/survanta","display_name":"Survanta","score":0.8299999833106995},{"id":"https://openalex.org/keywords/monolayer-collapse","display_name":"monolayer collapse","score":0.9179999828338623},{"id":"https://openalex.org/keywords/surface-pressure","display_name":"surface pressure","score":0.5389999747276306},{"id":"https://openalex.org/keywords/buckling","display_name":"buckling","score":0.7049999833106995},{"id":"https://openalex.org/keywords/multilayer-formation","display_name":"multilayer formation","score":0.8109999895095825},{"id":"https://openalex.org/keywords/supported-films","display_name":"supported films","score":0.47999998927116394},{"id":"https://openalex.org/keywords/membrane-topography","display_name":"membrane topography","score":0.722000002861023},{"id":"https://openalex.org/keywords/respiratory-distress-syndrome","display_name":"respiratory distress syndrome","score":0.7940000295639038},{"id":"https://openalex.org/keywords/high-resolution-imaging","display_name":"high-resolution imaging","score":0.3880000114440918}],"concepts":[{"id":"https://openalex.org/C7070889","wikidata":"https://www.wikidata.org/wiki/Q902488","display_name":"Monolayer","level":2,"score":0.9246056079864502},{"id":"https://openalex.org/C58226133","wikidata":"https://www.wikidata.org/wiki/Q1324199","display_name":"Pulmonary surfactant","level":2,"score":0.8217601180076599},{"id":"https://openalex.org/C192157962","wikidata":"https://www.wikidata.org/wiki/Q4087243","display_name":"Bilayer","level":3,"score":0.631219208240509},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.5569008588790894},{"id":"https://openalex.org/C101677414","wikidata":"https://www.wikidata.org/wiki/Q81809","display_name":"Surface pressure","level":2,"score":0.5333993434906006},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.47540339827537537},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.4310188293457031},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.42340147495269775},{"id":"https://openalex.org/C149288129","wikidata":"https://www.wikidata.org/wiki/Q185357","display_name":"Phase transition","level":2,"score":0.41816824674606323},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.35944998264312744},{"id":"https://openalex.org/C159467904","wikidata":"https://www.wikidata.org/wiki/Q2001702","display_name":"Chemical physics","level":1,"score":0.3268303871154785},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.3083145022392273},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.30746665596961975},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.26557737588882446},{"id":"https://openalex.org/C26873012","wikidata":"https://www.wikidata.org/wiki/Q214781","display_name":"Condensed matter physics","level":1,"score":0.12184914946556091},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10608971118927002},{"id":"https://openalex.org/C57879066","wikidata":"https://www.wikidata.org/wiki/Q41217","display_name":"Mechanics","level":1,"score":0.10318085551261902},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.09021124243736267},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001688","descriptor_name":"Biological Products","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D001688","descriptor_name":"Biological Products","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008856","descriptor_name":"Microscopy, Fluorescence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011312","descriptor_name":"Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011663","descriptor_name":"Pulmonary Surfactants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011663","descriptor_name":"Pulmonary Surfactants","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D018625","descriptor_name":"Microscopy, Atomic Force","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1562/0031-8655(2004)080<0471:hsolsc>2.0.co;2","doi":"https://doi.org/10.1562/0031-8655(2004)080<0471:hsolsc>2.0.co;2","is_oa":false,"landing_page_url":"https://doi.org/10.1562/0031-8655(2004)080<0471:hsolsc>2.0.co;2","pdf_url":null,"source":{"id":"https://openalex.org/S61245073","display_name":"Photochemistry and Photobiology","issn_l":"0031-8655","issn":["0031-8655","1751-1097"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Photochemistry and Photobiology","raw_type":"journal-article"},{"id":"pmid:15623332","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15623332","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Photochemistry and photobiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.46810001134872437,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2694106744","display_name":null,"funder_award_id":"GM55290","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G5633503774","display_name":" CA2+ REGULATES STRUCTURE/FUNCTION OF PORE COMPLEX","funder_award_id":"R01GM055290","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1579633546","https://openalex.org/W1666553655","https://openalex.org/W1973137795","https://openalex.org/W1975783967","https://openalex.org/W1989132333","https://openalex.org/W1992525885","https://openalex.org/W1999759414","https://openalex.org/W2018110297","https://openalex.org/W2025290188","https://openalex.org/W2029522896","https://openalex.org/W2036537138","https://openalex.org/W2044079201","https://openalex.org/W2055057098","https://openalex.org/W2055093309","https://openalex.org/W2062234578","https://openalex.org/W2067984340","https://openalex.org/W2070508462","https://openalex.org/W2085138690","https://openalex.org/W2090819119","https://openalex.org/W2098890790","https://openalex.org/W2108914108","https://openalex.org/W2133652131","https://openalex.org/W2136212902","https://openalex.org/W2160542981","https://openalex.org/W2171342833"],"related_works":["https://openalex.org/W1973188669","https://openalex.org/W2153443759","https://openalex.org/W2026769858","https://openalex.org/W2108914108","https://openalex.org/W3036851690","https://openalex.org/W2613886387","https://openalex.org/W2093781548","https://openalex.org/W2093419908","https://openalex.org/W2018165343","https://openalex.org/W1970534922"],"abstract_inverted_index":{"Survanta":[0,85],"is":[1,173,203,213],"a":[2,57,196],"replacement":[3],"lung":[4],"surfactant":[5,38],"(LS)":[6],"used":[7],"in":[8,23,49,131,156,166,171,217,239],"the":[9,16,24,37,66,88,99,111,132,136,153,157,183,187,192,201,218,235,240],"treatment":[10],"of":[11,20,29,70,90,101,127,182,209],"respiratory":[12,51],"distress":[13],"syndrome":[14],"(RDS),":[15],"fourth":[17],"leading":[18],"cause":[19],"infant":[21],"mortality":[22],"United":[25],"States.":[26],"It":[27],"consists":[28],"purified":[30],"LS":[31],"from":[32,77,84,138,195],"bovine":[33],"sources":[34],"and":[35,42,59,68,148,224],"retains":[36],"proteins":[39],"(SP)":[40],"SP-B":[41],"SP-C,":[43],"both":[44],"thought":[45],"to":[46,64,86,140,205,230],"be":[47],"important":[48],"proper":[50],"function.":[52],"As":[53],"such,":[54],"it":[55],"provides":[56],"useful":[58],"biologically":[60],"relevant":[61],"model":[62,81],"system":[63],"probe":[65,87],"structure":[67,130,185],"function":[69],"natural":[71],"LS.":[72],"Here,":[73],"we":[74],"report":[75],"results":[76,97],"high-resolution":[78],"studies":[79],"on":[80,122,178],"monolayers":[82],"formed":[83],"mechanism":[89],"collapse":[91,104,112,115,207],"at":[92,243],"high":[93],"surface":[94],"pressure.":[95,245],"Our":[96],"show":[98,151],"formation":[100,177],"two":[102],"different":[103],"structures.":[105],"At":[106],"62":[107],"mN/m,":[108,211],"slightly":[109],"below":[110],"pressure,":[113],"monolayer":[114,139,179,236],"occurs":[116,194],"through":[117],"buckling.":[118],"Confocal":[119],"fluorescence":[120,147,158],"measurements":[121,150,159],"supported":[123],"films":[124,133],"reveal":[125],"regions":[126],"overlapping":[128],"phase":[129,184],"that":[134,152,191,227],"mark":[135],"transition":[137,154],"multilayer.":[141],"Simultaneous":[142],"near-field":[143],"scanning":[144],"optical":[145],"microscopy":[146],"force":[149],"seen":[155],"accompanies":[160],"corresponding":[161],"approximately":[162],"4-5":[163],"nm":[164,232],"changes":[165],"membrane":[167],"topography.":[168],"This":[169],"change":[170],"height":[172],"consistent":[174],"with":[175],"bilayer":[176],"collapse.":[180],"Analysis":[181],"near":[186],"transitions":[188],"also":[189],"suggests":[190],"buckling":[193,212],"continuous":[197],"film.":[198],"However,":[199],"when":[200],"film":[202,242],"compressed":[204],"its":[206],"pressure":[208],"65":[210],"no":[214],"longer":[215],"evident":[216],"collapsed":[219,241],"region.":[220],"In":[221],"addition,":[222],"multilayers":[223],"lipid-protein":[225],"aggregates":[226],"are":[228,237],"up":[229],"40":[231],"higher":[233],"than":[234],"observed":[238],"this":[244]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2014,"cited_by_count":4},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}