{"id":"https://openalex.org/W2050123286","doi":"https://doi.org/10.1016/j.phrs.2008.09.002","title":"Dopamine receptor 3 (D3) knockout mice show regular emotional behaviour","display_name":"Dopamine receptor 3 (D3) knockout mice show regular emotional behaviour","publication_year":2008,"publication_date":"2008-09-12","ids":{"openalex":"https://openalex.org/W2050123286","doi":"https://doi.org/10.1016/j.phrs.2008.09.002","mag":"2050123286","pmid":"https://pubmed.ncbi.nlm.nih.gov/18832038"},"language":"en","primary_location":{"id":"doi:10.1016/j.phrs.2008.09.002","doi":"https://doi.org/10.1016/j.phrs.2008.09.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.phrs.2008.09.002","pdf_url":null,"source":{"id":"https://openalex.org/S54485712","display_name":"Pharmacological Research","issn_l":"1043-6618","issn":["1043-6618","1096-1186"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-1","oarl","poland-100"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmacological Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000507771","display_name":"Sabine Chourbaji","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]},{"id":"https://openalex.org/I4210105615","display_name":"Central Institute of Mental Health","ror":"https://ror.org/01hynnt93","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210105615"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"S CHOURBAJI","raw_affiliation_strings":["Central Institute of Mental Health Mannheim (ZI), University of Heidelberg, Mannheim, Germany. sabine.chourbaji@zi-mannheim.de","Central Institute of Mental Health Mannheim (ZI), University of Heidelberg, Mannheim, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Institute of Mental Health Mannheim (ZI), University of Heidelberg, Mannheim, Germany. sabine.chourbaji@zi-mannheim.de","institution_ids":["https://openalex.org/I223822909","https://openalex.org/I4210105615"]},{"raw_affiliation_string":"Central Institute of Mental Health Mannheim (ZI), University of Heidelberg, Mannheim, Germany","institution_ids":["https://openalex.org/I223822909","https://openalex.org/I4210105615"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040430866","display_name":"Christiane Brandwein","orcid":"https://orcid.org/0009-0008-5122-975X","observed_orcids":["https://orcid.org/0009-0008-5122-975X"]},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]},{"id":"https://openalex.org/I4210105615","display_name":"Central Institute of Mental Health","ror":"https://ror.org/01hynnt93","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210105615"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"C BRANDWEIN","raw_affiliation_strings":["Central Institute of Mental Health Mannheim (ZI), University of Heidelberg, Mannheim, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Institute of Mental Health Mannheim (ZI), University of Heidelberg, Mannheim, Germany","institution_ids":["https://openalex.org/I223822909","https://openalex.org/I4210105615"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043997083","display_name":"Miriam Annika Vogt","orcid":"https://orcid.org/0000-0002-3400-5067","observed_orcids":["https://orcid.org/0000-0002-3400-5067"]},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]},{"id":"https://openalex.org/I4210105615","display_name":"Central Institute of Mental Health","ror":"https://ror.org/01hynnt93","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210105615"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M VOGT","raw_affiliation_strings":["Central Institute of Mental Health Mannheim (ZI), University of Heidelberg, Mannheim, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Institute of Mental Health Mannheim (ZI), University of Heidelberg, Mannheim, Germany","institution_ids":["https://openalex.org/I223822909","https://openalex.org/I4210105615"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047571293","display_name":"Christof Dormann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]},{"id":"https://openalex.org/I4210105615","display_name":"Central Institute of Mental Health","ror":"https://ror.org/01hynnt93","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210105615"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"C DORMANN","raw_affiliation_strings":["Central Institute of Mental Health Mannheim (ZI), University of Heidelberg, Mannheim, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Institute of Mental Health Mannheim (ZI), University of Heidelberg, Mannheim, Germany","institution_ids":["https://openalex.org/I223822909","https://openalex.org/I4210105615"]}]},{"author_position":"middle","author":{"id":null,"display_name":"R MUELLER","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126753","display_name":"Abbott (Germany)","ror":"https://ror.org/02x2gk324","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210088555","https://openalex.org/I4210126753"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"R MUELLER","raw_affiliation_strings":["Neuroscience Research, GPRD, Abbott, Ludwigshafen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuroscience Research, GPRD, Abbott, Ludwigshafen, Germany","institution_ids":["https://openalex.org/I4210126753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010863641","display_name":"Karla U. Drescher","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126753","display_name":"Abbott (Germany)","ror":"https://ror.org/02x2gk324","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210088555","https://openalex.org/I4210126753"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"K DRESCHER","raw_affiliation_strings":["Neuroscience Research, GPRD, Abbott, Ludwigshafen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuroscience Research, GPRD, Abbott, Ludwigshafen, Germany","institution_ids":["https://openalex.org/I4210126753"]}]},{"author_position":"middle","author":{"id":null,"display_name":"G GROSS","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126753","display_name":"Abbott (Germany)","ror":"https://ror.org/02x2gk324","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210088555","https://openalex.org/I4210126753"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"G GROSS","raw_affiliation_strings":["Neuroscience Research, GPRD, Abbott, Ludwigshafen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuroscience Research, GPRD, Abbott, Ludwigshafen, Germany","institution_ids":["https://openalex.org/I4210126753"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037182482","display_name":"Peter Gass","orcid":"https://orcid.org/0000-0003-3959-6369","observed_orcids":["https://orcid.org/0000-0003-3959-6369"]},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]},{"id":"https://openalex.org/I4210105615","display_name":"Central Institute of Mental Health","ror":"https://ror.org/01hynnt93","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210105615"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"P GASS","raw_affiliation_strings":["Central Institute of Mental Health Mannheim (ZI), University of Heidelberg, Mannheim, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Institute of Mental Health Mannheim (ZI), University of Heidelberg, Mannheim, Germany","institution_ids":["https://openalex.org/I223822909","https://openalex.org/I4210105615"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5000507771"],"corresponding_institution_ids":["https://openalex.org/I223822909","https://openalex.org/I4210105615"],"apc_list":{"value":4130,"currency":"USD","value_usd":4130},"apc_paid":null,"fwci":0.6249,"has_fulltext":false,"cited_by_count":39,"citation_normalized_percentile":{"value":0.62089536,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"58","issue":"5-6","first_page":"302","last_page":"307"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dopamine-d3-receptor","display_name":"dopamine D3 receptor","score":0.8989999890327454},{"id":"https://openalex.org/keywords/depression","display_name":"depression","score":0.777999997138977},{"id":"https://openalex.org/keywords/depression-like-behavior","display_name":"depression-like behavior","score":0.9449999928474426},{"id":"https://openalex.org/keywords/anxiety-like-behavior","display_name":"anxiety-like behavior","score":0.8209999799728394},{"id":"https://openalex.org/keywords/locomotor-activity","display_name":"locomotor activity","score":0.7910000085830688},{"id":"https://openalex.org/keywords/exploratory-behavior","display_name":"exploratory behavior","score":0.5529999732971191},{"id":"https://openalex.org/keywords/learned-helplessness","display_name":"learned helplessness","score":0.9810000061988831},{"id":"https://openalex.org/keywords/sucrose-intake","display_name":"sucrose intake","score":0.9079999923706055},{"id":"https://openalex.org/keywords/forced-swim-test","display_name":"forced swim test","score":0.9769999980926514},{"id":"https://openalex.org/keywords/pharmacotherapy-targets","display_name":"pharmacotherapy targets","score":0.5230000019073486}],"concepts":[{"id":"https://openalex.org/C182704531","wikidata":"https://www.wikidata.org/wiki/Q1364740","display_name":"Knockout mouse","level":3,"score":0.7640594840049744},{"id":"https://openalex.org/C199596767","wikidata":"https://www.wikidata.org/wiki/Q21110872","display_name":"Dopamine receptor D3","level":4,"score":0.6665395498275757},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.47800958156585693},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.44323277473449707},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.41294047236442566},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4121289849281311},{"id":"https://openalex.org/C120069818","wikidata":"https://www.wikidata.org/wiki/Q415496","display_name":"Dopamine receptor","level":3,"score":0.3933295011520386},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3412885069847107},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3387875258922577},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3350730836391449},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32897263765335083}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D001522","descriptor_name":"Behavior, Animal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D004644","descriptor_name":"Emotions","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005106","descriptor_name":"Exploratory Behavior","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005518","descriptor_name":"Food Preferences","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006380","descriptor_name":"Helplessness, Learned","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008570","descriptor_name":"Memory, Short-Term","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013550","descriptor_name":"Swimming","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050637","descriptor_name":"Receptors, Dopamine D3","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.phrs.2008.09.002","doi":"https://doi.org/10.1016/j.phrs.2008.09.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.phrs.2008.09.002","pdf_url":null,"source":{"id":"https://openalex.org/S54485712","display_name":"Pharmacological Research","issn_l":"1043-6618","issn":["1043-6618","1096-1186"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-1","oarl","poland-100"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmacological Research","raw_type":"journal-article"},{"id":"pmid:18832038","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18832038","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmacological research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W72273208","https://openalex.org/W144082570","https://openalex.org/W413412879","https://openalex.org/W1569413811","https://openalex.org/W1787099843","https://openalex.org/W1969107429","https://openalex.org/W1969484863","https://openalex.org/W1971764800","https://openalex.org/W1974387854","https://openalex.org/W1980344452","https://openalex.org/W1989850259","https://openalex.org/W1990246484","https://openalex.org/W1992843119","https://openalex.org/W1994781509","https://openalex.org/W1998586143","https://openalex.org/W2002834809","https://openalex.org/W2002862767","https://openalex.org/W2004118951","https://openalex.org/W2007227244","https://openalex.org/W2013190001","https://openalex.org/W2014793858","https://openalex.org/W2018814167","https://openalex.org/W2019708552","https://openalex.org/W2021620079","https://openalex.org/W2022500690","https://openalex.org/W2028480779","https://openalex.org/W2029707852","https://openalex.org/W2031704537","https://openalex.org/W2041036432","https://openalex.org/W2047797962","https://openalex.org/W2051849699","https://openalex.org/W2061951979","https://openalex.org/W2071362963","https://openalex.org/W2077320328","https://openalex.org/W2086121200","https://openalex.org/W2086340893","https://openalex.org/W2088620464","https://openalex.org/W2089693821","https://openalex.org/W2091958139","https://openalex.org/W2094253961","https://openalex.org/W2123234814","https://openalex.org/W2127905906","https://openalex.org/W2129579280","https://openalex.org/W2141398558","https://openalex.org/W2149065848","https://openalex.org/W2153763527","https://openalex.org/W2160622942","https://openalex.org/W2197078876"],"related_works":["https://openalex.org/W2054294679","https://openalex.org/W1973581229","https://openalex.org/W2019708552","https://openalex.org/W1989850259","https://openalex.org/W2051460632","https://openalex.org/W2054902627","https://openalex.org/W3208622762","https://openalex.org/W2018814167","https://openalex.org/W7096997698","https://openalex.org/W1836371658"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":9}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}