{"id":"https://openalex.org/W2050092590","doi":"https://doi.org/10.1002/ijc.2910510312","title":"Expression and different polarity of aminopeptidase N in normal human colonic mucosa and colonic tumors","display_name":"Expression and different polarity of aminopeptidase N in normal human colonic mucosa and colonic tumors","publication_year":1992,"publication_date":"1992-05-28","ids":{"openalex":"https://openalex.org/W2050092590","doi":"https://doi.org/10.1002/ijc.2910510312","mag":"2050092590","pmid":"https://pubmed.ncbi.nlm.nih.gov/1375588"},"language":"en","primary_location":{"id":"doi:10.1002/ijc.2910510312","doi":"https://doi.org/10.1002/ijc.2910510312","is_oa":false,"landing_page_url":"https://doi.org/10.1002/ijc.2910510312","pdf_url":null,"source":{"id":"https://openalex.org/S5382288","display_name":"International Journal of Cancer","issn_l":"0020-7136","issn":["0020-7136","1097-0215"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Cancer","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070114434","display_name":"Andrea Quaroni","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Andrea Quaroni","raw_affiliation_strings":["Section of Physiology, Cornell Univesity, Ithaca, NY 14853","Cornell University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Physiology, Cornell Univesity, Ithaca, NY 14853","institution_ids":["https://openalex.org/I205783295"]},{"raw_affiliation_string":"Cornell University","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113562230","display_name":"Buford Lee Nichols","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210141908","display_name":"Children's Nutrition Research Center at Baylor College of Medicine","ror":"https://ror.org/03s936v76","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210141908","https://openalex.org/I4210145274"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Buford L. Nichols","raw_affiliation_strings":["Children's Nutrition Research Center, Houston, TX 77030"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children's Nutrition Research Center, Houston, TX 77030","institution_ids":["https://openalex.org/I4210141908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088357510","display_name":"Elaine G. Quaroni","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elaine Quaroni","raw_affiliation_strings":["Section of Physiology, Cornell University, Ithaca, NY I4853","Cornell University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Physiology, Cornell University, Ithaca, NY I4853","institution_ids":["https://openalex.org/I205783295"]},{"raw_affiliation_string":"Cornell University","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006527362","display_name":"Kelley R. Hurst","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kelley Hurst","raw_affiliation_strings":["Section of Physiology, Cornell University, Ithaca, NY I4853","Cornell University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Physiology, Cornell University, Ithaca, NY I4853","institution_ids":["https://openalex.org/I205783295"]},{"raw_affiliation_string":"Cornell University","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103410306","display_name":"Lemuel O. Herrera","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lemuel Herrera","raw_affiliation_strings":["Division of Surgical Oncology, Medical Center of Delaware, Wilmington, DE 19899","Medical Center of Delaware"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Surgical Oncology, Medical Center of Delaware, Wilmington, DE 19899","institution_ids":[]},{"raw_affiliation_string":"Medical Center of Delaware","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065235268","display_name":"Milton M. Weiser","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1289499695","display_name":"Women & Children's Hospital of Buffalo","ror":"https://ror.org/00kg66g91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1289499695"]},{"id":"https://openalex.org/I4210157091","display_name":"Buffalo General Medical Center","ror":"https://ror.org/04ngv0f69","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1325611130","https://openalex.org/I4210157091"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Milton M. Weiser","raw_affiliation_strings":["Division of Gastroenterology, Hepatology and Nutrition, Buffalo General Hospital, Buffalo, NY 14203","Women and Children's Hospital of Buffalo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Hepatology and Nutrition, Buffalo General Hospital, Buffalo, NY 14203","institution_ids":["https://openalex.org/I4210157091"]},{"raw_affiliation_string":"Women and Children's Hospital of Buffalo","institution_ids":["https://openalex.org/I1289499695"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078636533","display_name":"Stanley R. Hamilton","orcid":"https://orcid.org/0000-0002-8331-1052","observed_orcids":["https://orcid.org/0000-0002-8331-1052"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stanley R. Hamilton","raw_affiliation_strings":["Department of Pathology and Oncology Center, Johns Hopkins University Medical School, Baltimore, MD 21205, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Oncology Center, Johns Hopkins University Medical School, Baltimore, MD 21205, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5070114434"],"corresponding_institution_ids":["https://openalex.org/I205783295"],"apc_list":{"value":5030,"currency":"USD","value_usd":5030},"apc_paid":null,"fwci":0.6397,"has_fulltext":false,"cited_by_count":26,"citation_normalized_percentile":{"value":0.71357479,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"51","issue":"3","first_page":"404","last_page":"411"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12505","display_name":"Peptidase Inhibition and Analysis","score":0.9496999979019165,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12505","display_name":"Peptidase Inhibition and Analysis","score":0.9496999979019165,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.017500000074505806,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13199","display_name":"Digestive system and related health","score":0.01720000058412552,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cd13","display_name":"CD13","score":1.0},{"id":"https://openalex.org/keywords/brush-border-enzymes","display_name":"brush border enzymes","score":0.796999990940094},{"id":"https://openalex.org/keywords/colonic-mucosa","display_name":"colonic mucosa","score":0.9610000252723694},{"id":"https://openalex.org/keywords/colon-adenoma","display_name":"colonic adenoma","score":0.718999981880188},{"id":"https://openalex.org/keywords/colorectal-adenocarcinoma","display_name":"colorectal adenocarcinoma","score":0.8600000143051147},{"id":"https://openalex.org/keywords/colonic-polyps","display_name":"colonic polyps","score":0.8949999809265137},{"id":"https://openalex.org/keywords/hyperplastic-polyps","display_name":"hyperplastic polyps","score":0.7870000004768372},{"id":"https://openalex.org/keywords/apical-membrane-localization","display_name":"apical membrane localization","score":0.7049999833106995},{"id":"https://openalex.org/keywords/intracellular-sorting","display_name":"intracellular sorting","score":0.527999997138977},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"carcinogenesis","score":0.8109999895095825},{"id":"https://openalex.org/keywords/dukes-stage","display_name":"Dukes stage","score":0.6539999842643738},{"id":"https://openalex.org/keywords/tumor-differentiation","display_name":"tumor differentiation","score":0.5569999814033508}],"concepts":[{"id":"https://openalex.org/C2777361361","wikidata":"https://www.wikidata.org/wiki/Q1112585","display_name":"Polarity (international relations)","level":3,"score":0.6051616072654724},{"id":"https://openalex.org/C2780985610","wikidata":"https://www.wikidata.org/wiki/Q419527","display_name":"Aminopeptidase","level":4,"score":0.5958049297332764},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5039843916893005},{"id":"https://openalex.org/C3019368612","wikidata":"https://www.wikidata.org/wiki/Q17154506","display_name":"Intestinal mucosa","level":2,"score":0.47030943632125854},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4131471514701843},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.39701640605926514},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3779919147491455},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.35287943482398987},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3288876414299011},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16517147421836853},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.08048510551452637},{"id":"https://openalex.org/C2776580952","wikidata":"https://www.wikidata.org/wiki/Q483745","display_name":"Leucine","level":3,"score":0.07880845665931702},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000626","descriptor_name":"Aminopeptidases","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000939","descriptor_name":"Epitopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003106","descriptor_name":"Colon","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D004152","descriptor_name":"Dipeptidyl-Peptidases and Tripeptidyl-Peptidases","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005190","descriptor_name":"Family","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013394","descriptor_name":"Sucrase-Isomaltase Complex","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D018819","descriptor_name":"Dipeptidyl Peptidase 4","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018826","descriptor_name":"CD13 Antigens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/ijc.2910510312","doi":"https://doi.org/10.1002/ijc.2910510312","is_oa":false,"landing_page_url":"https://doi.org/10.1002/ijc.2910510312","pdf_url":null,"source":{"id":"https://openalex.org/S5382288","display_name":"International Journal of Cancer","issn_l":"0020-7136","issn":["0020-7136","1097-0215"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Cancer","raw_type":"journal-article"},{"id":"pmid:1375588","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1375588","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of cancer","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G5827798698","display_name":"INTESTINAL CELL DIFFERENTIATION IN VIVO AND IN CULTURE","funder_award_id":"R01DK032656","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G6181285312","display_name":"CRYPT CELL ANTIGENS AS MARKERS FOR COLON CANCER","funder_award_id":"R01CA044714","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7664101333","display_name":null,"funder_award_id":"R0-CA44714","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8871449279","display_name":"INHERITANCE AND MARKERS OF COLORECTAL CANCER AND POLYPS","funder_award_id":"R01CA045831","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332605","display_name":"Agricultural Research Service","ror":"https://ror.org/02d2m2044"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W1495482193","https://openalex.org/W1553017304","https://openalex.org/W1570262416","https://openalex.org/W1726708958","https://openalex.org/W1759909619","https://openalex.org/W1921570207","https://openalex.org/W1963958199","https://openalex.org/W1965102714","https://openalex.org/W1983190250","https://openalex.org/W1997986612","https://openalex.org/W1999203970","https://openalex.org/W2001812443","https://openalex.org/W2009086732","https://openalex.org/W2029056840","https://openalex.org/W2041805545","https://openalex.org/W2053713198","https://openalex.org/W2065607376","https://openalex.org/W2066719256","https://openalex.org/W2084646826","https://openalex.org/W2097598566","https://openalex.org/W2101108802","https://openalex.org/W2106823947","https://openalex.org/W2108165275","https://openalex.org/W2108885642","https://openalex.org/W2111509152","https://openalex.org/W2115945894","https://openalex.org/W2128401222","https://openalex.org/W2182432763","https://openalex.org/W2284013506","https://openalex.org/W2341803145","https://openalex.org/W4301348240"],"related_works":["https://openalex.org/W2141140788","https://openalex.org/W2078440077","https://openalex.org/W1896007159","https://openalex.org/W1495482193","https://openalex.org/W2111509152","https://openalex.org/W2348267685","https://openalex.org/W2128401222","https://openalex.org/W2156223179","https://openalex.org/W2069055102","https://openalex.org/W2043293376"],"abstract_inverted_index":{"Expression":[0],"and":[1,19,51,56,61,116,119,148,163,199,211],"cellular":[2,166],"localization":[3],"of":[4,28,79,86,92,105,122,168,206,218,232],"brush-border":[5],"enzymes":[6,39],"(aminopeptidase":[7],"N,":[8],"dipeptidylpeptidase":[9],"IV,":[10,59],"lactase,":[11],"maltase)":[12],"in":[13,83,109,132,139,145,189,196,203],"normal":[14],"human":[15,191],"colon,":[16,192],"colonic":[17,133],"polyps":[18],"malignant":[20],"intestinal":[21,93],"tumors":[22,174],"were":[23,40,63,175],"investigated":[24],"with":[25,32],"a":[26,222],"panel":[27],"monoclonal":[29],"antibodies":[30],"reacting":[31],"either":[33],"native":[34],"or":[35,49,165,177],"denatured":[36],"proteins.":[37],"The":[38],"detected":[41,74],"on":[42],"cryostat":[43],"sections":[44],"by":[45,53,160],"indirect":[46],"immunofluorescence":[47],"staining,":[48],"affinity-purified":[50],"analyzed":[52],"gel":[54],"electrophoresis":[55],"immunoblotting.":[57],"Dipeptidylpeptidase":[58],"lactase":[60],"maltase":[62],"absent":[64],"from":[65,89,120],"all":[66,172],"samples":[67],"examined,":[68],"while":[69],"aminopeptidase":[70,169,184],"N":[71,185],"(APN)":[72],"was":[73,98,129,137,154],"at":[75,101,228],"the":[76,80,102,106,197],"basal":[77],"membrane":[78,104,143],"epithelial":[81,194],"cells":[82,195],"most":[84],"specimens":[85],"colon":[87,124],"obtained":[88],"individuals":[90],"free":[91],"tumors.":[94],"In":[95],"contrast,":[96],"APN":[97,128],"frequently":[99],"localized":[100],"luminal":[103],"surface":[107,220],"epithelium":[108],"large-intestinal":[110],"mucosa":[111],"distal":[112],"to":[113],"tumors,":[114,134],"adenomas":[115,147],"hyperplastic":[117],"polyps,":[118],"members":[121],"hereditary":[123],"cancer":[125],"syndrome":[126],"families.":[127],"also":[130],"expressed":[131,188],"where":[135],"it":[136,214],"present":[138],"an":[140,229],"apical":[141],"cell":[142],"location":[144,167],"3/23":[146],"14/35":[149],"adenocarcinomas":[150],"examined.":[151],"No":[152],"correlation":[153],"found":[155],"between":[156],"tumor-cell":[157],"invasiveness":[158],"(classified":[159],"\"Dukes\"":[161],"stage)":[162],"expression":[164],"N.":[170],"Histologically,":[171],"positive":[173],"moderately":[176],"well":[178],"differentiated.":[179],"These":[180],"results":[181],"suggest":[182],"that":[183],"is":[186],"normally":[187],"adult":[190],"but":[193],"large":[198],"small":[200],"intestine":[201],"differ":[202],"their":[204,219],"ways":[205],"sorting":[207],"this":[208],"enzyme":[209],"intracellularly":[210],"eventually":[212],"inserting":[213],"into":[215],"different":[216],"aspects":[217],"membrane,":[221],"process":[223],"which":[224],"may":[225],"be":[226],"altered":[227],"early":[230],"stage":[231],"carcinogenesis.":[233]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}