{"id":"https://openalex.org/W2050043316","doi":"https://doi.org/10.1016/j.bbmt.2007.05.014","title":"Deletion of the Short Arm of Chromosome 1 (del 1p) is a Strong Predictor of Poor Outcome in Myeloma Patients Undergoing an Autotransplant","display_name":"Deletion of the Short Arm of Chromosome 1 (del 1p) is a Strong Predictor of Poor Outcome in Myeloma Patients Undergoing an Autotransplant","publication_year":2007,"publication_date":"2007-07-17","ids":{"openalex":"https://openalex.org/W2050043316","doi":"https://doi.org/10.1016/j.bbmt.2007.05.014","mag":"2050043316","pmid":"https://pubmed.ncbi.nlm.nih.gov/17697969"},"language":"en","primary_location":{"id":"doi:10.1016/j.bbmt.2007.05.014","doi":"https://doi.org/10.1016/j.bbmt.2007.05.014","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2007.05.014","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.bbmt.2007.05.014","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015342719","display_name":"Muzaffar H. Qazilbash","orcid":"https://orcid.org/0000-0003-2876-2886","observed_orcids":["https://orcid.org/0000-0003-2876-2886"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Muzaffar H. Qazilbash","raw_affiliation_strings":["Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas 77030, USA. mqazilba@mdanderson.org","Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas 77030, USA. mqazilba@mdanderson.org","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111618322","display_name":"Rima M. Saliba","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rima M. Saliba","raw_affiliation_strings":["Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071024715","display_name":"Bilal Ahmed","orcid":"https://orcid.org/0000-0001-6021-1414","observed_orcids":["https://orcid.org/0000-0001-6021-1414"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bilal Ahmed","raw_affiliation_strings":["Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016790308","display_name":"Gaurav C. Parikh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gaurav Parikh","raw_affiliation_strings":["Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113997812","display_name":"Floralyn L. Mendoza","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Floralyn Mendoza","raw_affiliation_strings":["Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112254523","display_name":"Noman Ashraf","orcid":"https://orcid.org/0000-0001-8637-1571","observed_orcids":["https://orcid.org/0000-0001-8637-1571"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Noman Ashraf","raw_affiliation_strings":["Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050962913","display_name":"Chitra M. Hosing","orcid":"https://orcid.org/0000-0003-0409-5556","observed_orcids":["https://orcid.org/0000-0003-0409-5556"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chitra Hosing","raw_affiliation_strings":["Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082739674","display_name":"Thuy Flosser","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thuy Flosser","raw_affiliation_strings":["Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113916086","display_name":"Donna M. Weber","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Donna M. Weber","raw_affiliation_strings":["Lymphoma and Myeloma, UT-M.D. Anderson Cancer Center, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lymphoma and Myeloma, UT-M.D. Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100438316","display_name":"Michael L. Wang","orcid":"https://orcid.org/0000-0001-9748-5486","observed_orcids":["https://orcid.org/0000-0001-9748-5486"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Wang","raw_affiliation_strings":["Lymphoma and Myeloma, UT-M.D. Anderson Cancer Center, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lymphoma and Myeloma, UT-M.D. Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065661042","display_name":"Daniel R. Couriel","orcid":"https://orcid.org/0000-0001-8167-4282","observed_orcids":["https://orcid.org/0000-0001-8167-4282"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel R. Couriel","raw_affiliation_strings":["Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066894053","display_name":"Uday Popat","orcid":"https://orcid.org/0000-0002-7592-2224","observed_orcids":["https://orcid.org/0000-0002-7592-2224"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Uday Popat","raw_affiliation_strings":["Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069460930","display_name":"Partow Kebriaei","orcid":"https://orcid.org/0000-0002-8607-9404","observed_orcids":["https://orcid.org/0000-0002-8607-9404"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Partow Kebriaei","raw_affiliation_strings":["Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034104852","display_name":"Amin Majid Alousi","orcid":"https://orcid.org/0000-0002-2498-8573","observed_orcids":["https://orcid.org/0000-0002-2498-8573"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amin M. Alousi","raw_affiliation_strings":["Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083279961","display_name":"Paolo N. Anderlini","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paolo Anderlini","raw_affiliation_strings":["Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070216340","display_name":"Rizwan C. Naeem","orcid":"https://orcid.org/0000-0002-8574-0184","observed_orcids":["https://orcid.org/0000-0002-8574-0184"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rizwan C. Naeem","raw_affiliation_strings":["Texas Children\u2019s Cancer Center and Baylor College of Medicine, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Texas Children\u2019s Cancer Center and Baylor College of Medicine, Houston, Texas","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048913229","display_name":"Richard E. Champlin","orcid":"https://orcid.org/0000-0002-4314-5037","observed_orcids":["https://orcid.org/0000-0002-4314-5037"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard E. Champlin","raw_affiliation_strings":["Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070096873","display_name":"Sergio  A. Giralt","orcid":"https://orcid.org/0000-0003-1944-5053","observed_orcids":["https://orcid.org/0000-0003-1944-5053"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sergio A. Giralt","raw_affiliation_strings":["Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stem Cell Transplantation and Cellular Therapy, UT-M.D. Anderson Cancer Center, Houston, Texas","institution_ids":["https://openalex.org/I1343551460"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5015342719"],"corresponding_institution_ids":["https://openalex.org/I1343551460"],"apc_list":{"value":3650,"currency":"USD","value_usd":3650},"apc_paid":{"value":3650,"currency":"USD","value_usd":3650},"fwci":1.7046,"has_fulltext":false,"cited_by_count":50,"citation_normalized_percentile":{"value":0.84890998,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"13","issue":"9","first_page":"1066","last_page":"1072"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10649","display_name":"Multiple Myeloma Research and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10649","display_name":"Multiple Myeloma Research and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14078","display_name":"Multiple and Secondary Primary Cancers","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multiple-myeloma","display_name":"multiple myeloma","score":0.8799999952316284},{"id":"https://openalex.org/keywords/chromosome-1p-loss","display_name":"chromosome 1p deletion","score":0.8650000095367432},{"id":"https://openalex.org/keywords/autologous-stem-cell-transplantation","display_name":"autologous stem cell transplantation","score":0.8939999938011169},{"id":"https://openalex.org/keywords/clonal-chromosomal-abnormalities","display_name":"clonal chromosomal abnormalities","score":0.828000009059906},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.8050000071525574},{"id":"https://openalex.org/keywords/progression-free-survival","display_name":"progression-free survival","score":0.9380000233650208},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9990000128746033},{"id":"https://openalex.org/keywords/high-dose-melphalan","display_name":"high-dose melphalan","score":0.890999972820282},{"id":"https://openalex.org/keywords/topotecan","display_name":"topotecan","score":0.8389999866485596},{"id":"https://openalex.org/keywords/hyperdiploidy","display_name":"hyperdiploidy","score":0.8330000042915344}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8778492212295532},{"id":"https://openalex.org/C2778684742","wikidata":"https://www.wikidata.org/wiki/Q2298283","display_name":"Melphalan","level":3,"score":0.7431967854499817},{"id":"https://openalex.org/C2776364478","wikidata":"https://www.wikidata.org/wiki/Q467635","display_name":"Multiple myeloma","level":2,"score":0.6900261044502258},{"id":"https://openalex.org/C144301174","wikidata":"https://www.wikidata.org/wiki/Q7893852","display_name":"Univariate analysis","level":3,"score":0.6378612518310547},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5977590084075928},{"id":"https://openalex.org/C2779050716","wikidata":"https://www.wikidata.org/wiki/Q4826373","display_name":"Autologous stem-cell transplantation","level":3,"score":0.5030831694602966},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.48112955689430237},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.45811715722084045},{"id":"https://openalex.org/C2776755627","wikidata":"https://www.wikidata.org/wiki/Q408524","display_name":"Cyclophosphamide","level":3,"score":0.4489452540874481},{"id":"https://openalex.org/C2781413609","wikidata":"https://www.wikidata.org/wiki/Q7308373","display_name":"Regimen","level":2,"score":0.43846818804740906},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4116595685482025},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3841346204280853},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.2733510136604309},{"id":"https://openalex.org/C38180746","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate analysis","level":2,"score":0.22538581490516663}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000971","descriptor_name":"Antineoplastic Combined Chemotherapy Protocols","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002872","descriptor_name":"Chromosome Deletion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002878","descriptor_name":"Chromosomes, Human, Pair 1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008558","descriptor_name":"Melphalan","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014182","descriptor_name":"Transplantation, Autologous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018380","descriptor_name":"Hematopoietic Stem Cell Transplantation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D018380","descriptor_name":"Hematopoietic Stem Cell Transplantation","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.bbmt.2007.05.014","doi":"https://doi.org/10.1016/j.bbmt.2007.05.014","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2007.05.014","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"},{"id":"pmid:17697969","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17697969","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.bbmt.2007.05.014","doi":"https://doi.org/10.1016/j.bbmt.2007.05.014","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2007.05.014","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W120865734","https://openalex.org/W1481398283","https://openalex.org/W1595870389","https://openalex.org/W1863464809","https://openalex.org/W1918030391","https://openalex.org/W1944291718","https://openalex.org/W1977707370","https://openalex.org/W1978377409","https://openalex.org/W1990009253","https://openalex.org/W1991704023","https://openalex.org/W1993549070","https://openalex.org/W2006321868","https://openalex.org/W2006382315","https://openalex.org/W2006914937","https://openalex.org/W2016073589","https://openalex.org/W2041591102","https://openalex.org/W2053633180","https://openalex.org/W2054290966","https://openalex.org/W2056742311","https://openalex.org/W2069267068","https://openalex.org/W2075669617","https://openalex.org/W2084499660","https://openalex.org/W2084657347","https://openalex.org/W2090370198","https://openalex.org/W2096048221","https://openalex.org/W2102591890","https://openalex.org/W2103101762","https://openalex.org/W2107057207","https://openalex.org/W2110486997","https://openalex.org/W2113424017","https://openalex.org/W2118102989","https://openalex.org/W2121081280","https://openalex.org/W2148672632","https://openalex.org/W2150997370","https://openalex.org/W2152333590","https://openalex.org/W2164807675","https://openalex.org/W2165341494","https://openalex.org/W2166508172","https://openalex.org/W2320578512","https://openalex.org/W2333363976","https://openalex.org/W2428771541","https://openalex.org/W3145716452","https://openalex.org/W4244791978","https://openalex.org/W6639265441","https://openalex.org/W6647491290","https://openalex.org/W6678089506"],"related_works":["https://openalex.org/W2547147024","https://openalex.org/W4412891869","https://openalex.org/W2593224771","https://openalex.org/W2560444220","https://openalex.org/W2331563431","https://openalex.org/W2550446565","https://openalex.org/W2999774001","https://openalex.org/W4389219767","https://openalex.org/W4403634972","https://openalex.org/W2000114835"],"abstract_inverted_index":{"Several":[0],"chromosomal":[1,104],"abnormalities":[2,22,60,105,188,204],"detected":[3,62],"by":[4,65],"conventional":[5,66],"cytogenetic":[6,42,67,187],"analysis":[7,68],"have":[8],"an":[9],"adverse":[10],"impact":[11],"on":[12],"the":[13,35,150,157],"outcome":[14,36],"in":[15,69,123,175,220],"myeloma":[16,55],"patients.":[17,71,125],"A":[18],"wide":[19],"spectrum":[20],"of":[21,37,94,108,115],"involving":[23],"chromosomes":[24],"1,":[25],"13,":[26],"14,":[27],"and":[28,48,81,97,119,156,170,181,198,206,218,225],"17":[29],"has":[30],"been":[31],"described.":[32],"We":[33],"analyzed":[34],"83":[38,70],"patients":[39,130,176,185,201,221],"with":[40,177,202,213],"clonal":[41],"abnormalities,":[43],"who":[44],"underwent":[45,73],"high-dose":[46,87,223],"therapy":[47,224],"autologous":[49,76,228],"stem":[50],"cell":[51],"transplantation":[52],"for":[53,149,230],"multiple":[54],"at":[56,63],"our":[57],"institution.":[58],"Clonal":[59],"were":[61,106,172],"diagnosis":[64,137],"Patients":[72],"a":[74,92,214,226],"single":[75,227],"transplant":[77,229],"between":[78],"April":[79],"2000":[80],"May":[82],"2005.":[83],"Preparative":[84],"regimen":[85],"was":[86,131,140,153,162],"melphalan":[88],"alone":[89],"(73),":[90],"or":[91],"combination":[93],"topotecan,":[95],"melphalan,":[96],"cyclophosphamide":[98],"(TMC=10).":[99],"The":[100],"most":[101],"commonly":[102],"observed":[103],"deletion":[107,114,178],"chromosome":[109,116],"13":[110],"(32%),":[111],"hyperdiploidy":[112],"(21%),":[113],"1p":[117,179,210],"(18%),":[118],"t":[120],"(11;":[121],"14)":[122],"7%":[124],"Median":[126,134,145],"follow-up":[127],"among":[128],"surviving":[129],"25.5":[132],"months.":[133,164],"interval":[135],"from":[136],"to":[138,190,193],"autotransplant":[139,194],"7.7":[141],"months":[142,155],"(range:":[143],"2.5-52).":[144],"progression-free":[146],"survival":[147,160,219],"(PFS)":[148],"entire":[151],"group":[152],"19":[154],"median":[158],"overall":[159],"(OS)":[161],"52":[163],"On":[165],"univariate":[166],"analysis,":[167],"both":[168],"PFS":[169,197],"OS":[171,199],"significantly":[173,215],"shorter":[174,216],"(P=.001":[180],"<.0001,":[182],"respectively).":[183,208],"Thirty-two":[184],"whose":[186],"returned":[189],"normal":[191],"prior":[192],"had":[195],"longer":[196],"than":[200],"persistent":[203],"(P=.02":[205],".08,":[207],"Deletion":[209],"is":[211],"associated":[212],"remission":[217],"undergoing":[222],"myeloma.":[231]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":6}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}