{"id":"https://openalex.org/W2049680397","doi":"https://doi.org/10.1016/j.redox.2014.10.003","title":"Natural thermal adaptation increases heat shock protein levels and decreases oxidative stress","display_name":"Natural thermal adaptation increases heat shock protein levels and decreases oxidative stress","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2049680397","doi":"https://doi.org/10.1016/j.redox.2014.10.003","mag":"2049680397","pmid":"https://pubmed.ncbi.nlm.nih.gov/25462062","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4225528"},"language":"en","primary_location":{"id":"doi:10.1016/j.redox.2014.10.003","doi":"https://doi.org/10.1016/j.redox.2014.10.003","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.redox.2014.10.003","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2213231714001098/pdf","source":{"id":"https://openalex.org/S2764928002","display_name":"Redox Biology","issn_l":"2213-2317","issn":["2213-2317"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Redox Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.sciencedirect.com/science/article/pii/S2213231714001098/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087842948","display_name":"Niku Oksala","orcid":"https://orcid.org/0000-0001-5336-3719","observed_orcids":["https://orcid.org/0000-0001-5336-3719"]},"institutions":[{"id":"https://openalex.org/I175532246","display_name":"University of Eastern Finland","ror":"https://ror.org/00cyydd11","country_code":"FI","type":"education","lineage":["https://openalex.org/I175532246"]},{"id":"https://openalex.org/I4210126318","display_name":"Tampere University Hospital","ror":"https://ror.org/02hvt5f17","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I4210126318"]},{"id":"https://openalex.org/I4387153886","display_name":"University of Tampere","ror":"https://ror.org/05p6qqk79","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Niku K.J. Oksala","raw_affiliation_strings":["Institute of Biomedicine, Department of Physiology, University of Eastern Finland, Kuopio, Finland; Department of Surgery, Medical School, University of Tampere and Tampere University Hospital, Tampere, Finland","Department of Surgery, Medical School, University of Tampere and Tampere University Hospital, Tampere, Finland","Institute of Biomedicine, Department of Physiology, University of Eastern Finland, Kuopio, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biomedicine, Department of Physiology, University of Eastern Finland, Kuopio, Finland; Department of Surgery, Medical School, University of Tampere and Tampere University Hospital, Tampere, Finland","institution_ids":["https://openalex.org/I175532246","https://openalex.org/I4210126318","https://openalex.org/I4387153886"]},{"raw_affiliation_string":"Department of Surgery, Medical School, University of Tampere and Tampere University Hospital, Tampere, Finland","institution_ids":["https://openalex.org/I4210126318","https://openalex.org/I4387153886"]},{"raw_affiliation_string":"Institute of Biomedicine, Department of Physiology, University of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026225236","display_name":"Fitnat G\u00fcler Ekmek\u00e7\u0131","orcid":"https://orcid.org/0000-0002-2275-5135","observed_orcids":["https://orcid.org/0000-0002-2275-5135"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"F. G\u00fcler Ekmek\u00e7i","raw_affiliation_strings":["Department of Biology, Faculty of Science, University of Hacettepe, Beytepe, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Faculty of Science, University of Hacettepe, Beytepe, Turkey","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111482130","display_name":"Ergi Deniz \u00d6zsoy","orcid":"https://orcid.org/0009-0007-5460-1003","observed_orcids":["https://orcid.org/0009-0007-5460-1003","https://orcid.org/0000-0002-1339-0971"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ergi \u00d6zsoy","raw_affiliation_strings":["Department of Biology, Faculty of Science, University of Hacettepe, Beytepe, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Faculty of Science, University of Hacettepe, Beytepe, Turkey","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023844382","display_name":"\u015eerife G\u00fcls\u00fcn K\u0131rankaya","orcid":"https://orcid.org/0000-0003-2069-9974","observed_orcids":["https://orcid.org/0000-0003-2069-9974"]},"institutions":[{"id":"https://openalex.org/I54001450","display_name":"D\u00fczce \u00dcniversitesi","ror":"https://ror.org/04175wc52","country_code":"TR","type":"education","lineage":["https://openalex.org/I54001450"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"\u015eerife Kirankaya","raw_affiliation_strings":["Department of Biology, Faculty of Science and Literature, University of D\u00fczce, D\u00fczce, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Faculty of Science and Literature, University of D\u00fczce, D\u00fczce, Turkey","institution_ids":["https://openalex.org/I54001450"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059442267","display_name":"Tarja Kokkola","orcid":"https://orcid.org/0000-0002-3303-3912","observed_orcids":["https://orcid.org/0000-0002-3303-3912"]},"institutions":[{"id":"https://openalex.org/I175532246","display_name":"University of Eastern Finland","ror":"https://ror.org/00cyydd11","country_code":"FI","type":"education","lineage":["https://openalex.org/I175532246"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Tarja Kokkola","raw_affiliation_strings":["Institute of Biomedicine, Department of Physiology, University of Eastern Finland, Kuopio, Finland; School of Pharmacy, University of Eastern Finland, Kuopio, Finland","Institute of Biomedicine, Department of Physiology, University of Eastern Finland, Kuopio, Finland","School of Pharmacy, University of Eastern Finland, Kuopio, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biomedicine, Department of Physiology, University of Eastern Finland, Kuopio, Finland; School of Pharmacy, University of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]},{"raw_affiliation_string":"Institute of Biomedicine, Department of Physiology, University of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]},{"raw_affiliation_string":"School of Pharmacy, University of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084699111","display_name":"G\u00fczin Emecen","orcid":"https://orcid.org/0000-0001-9223-7205","observed_orcids":["https://orcid.org/0000-0001-9223-7205"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"G\u00fczin Emecen","raw_affiliation_strings":["Department of Biology, Faculty of Science, University of Hacettepe, Beytepe, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Faculty of Science, University of Hacettepe, Beytepe, Turkey","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077618588","display_name":"Jani Lappalainen","orcid":"https://orcid.org/0000-0003-2335-615X","observed_orcids":["https://orcid.org/0000-0003-2335-615X"]},"institutions":[{"id":"https://openalex.org/I175532246","display_name":"University of Eastern Finland","ror":"https://ror.org/00cyydd11","country_code":"FI","type":"education","lineage":["https://openalex.org/I175532246"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Jani Lappalainen","raw_affiliation_strings":["Institute of Biomedicine, Department of Physiology, University of Eastern Finland, Kuopio, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biomedicine, Department of Physiology, University of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021448617","display_name":"Kai Kaarniranta","orcid":"https://orcid.org/0000-0003-2600-8679","observed_orcids":["https://orcid.org/0000-0003-2600-8679"]},"institutions":[{"id":"https://openalex.org/I175532246","display_name":"University of Eastern Finland","ror":"https://ror.org/00cyydd11","country_code":"FI","type":"education","lineage":["https://openalex.org/I175532246"]},{"id":"https://openalex.org/I4210092991","display_name":"Kuopio University Hospital","ror":"https://ror.org/00fqdfs68","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I4210092991","https://openalex.org/I4405278559"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Kai Kaarniranta","raw_affiliation_strings":["Department of Ophthalmology, Institute of Clinical Medicine, University of Eastern Finland, Finland; Department of Ophthalmology, Kuopio University Hospital, Kuopio, Finland","Department of Ophthalmology, Institute of Clinical Medicine, University of Eastern Finland, Finland","Department of Ophthalmology, Kuopio University Hospital, Kuopio, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Institute of Clinical Medicine, University of Eastern Finland, Finland; Department of Ophthalmology, Kuopio University Hospital, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246","https://openalex.org/I4210092991"]},{"raw_affiliation_string":"Department of Ophthalmology, Institute of Clinical Medicine, University of Eastern Finland, Finland","institution_ids":["https://openalex.org/I175532246"]},{"raw_affiliation_string":"Department of Ophthalmology, Kuopio University Hospital, Kuopio, Finland","institution_ids":["https://openalex.org/I4210092991"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028187109","display_name":"Mustafa Atalay","orcid":"https://orcid.org/0000-0001-8999-1426","observed_orcids":["https://orcid.org/0000-0001-8999-1426"]},"institutions":[{"id":"https://openalex.org/I175532246","display_name":"University of Eastern Finland","ror":"https://ror.org/00cyydd11","country_code":"FI","type":"education","lineage":["https://openalex.org/I175532246"]}],"countries":["FI"],"is_corresponding":true,"raw_author_name":"Mustafa Atalay","raw_affiliation_strings":["Institute of Biomedicine, Department of Physiology, University of Eastern Finland, Kuopio, Finland. Electronic address: mustafa.atalay@uef.fi","Institute of Biomedicine, Department of Physiology, University of Eastern Finland, Kuopio, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biomedicine, Department of Physiology, University of Eastern Finland, Kuopio, Finland. Electronic address: mustafa.atalay@uef.fi","institution_ids":["https://openalex.org/I175532246"]},{"raw_affiliation_string":"Institute of Biomedicine, Department of Physiology, University of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5028187109"],"corresponding_institution_ids":["https://openalex.org/I175532246"],"apc_list":{"value":4310,"currency":"USD","value_usd":4310},"apc_paid":{"value":4310,"currency":"USD","value_usd":4310},"fwci":2.2031,"has_fulltext":true,"cited_by_count":136,"citation_normalized_percentile":{"value":0.88674201,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"3","issue":null,"first_page":"25","last_page":"28"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11056","display_name":"Physiological and biochemical adaptations","score":0.016899999231100082,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10447","display_name":"Environmental Toxicology and Ecotoxicology","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heat-shock-proteins","display_name":"heat shock proteins","score":1.0},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9739999771118164},{"id":"https://openalex.org/keywords/thermal-adaptation","display_name":"thermal adaptation","score":0.8980000019073486},{"id":"https://openalex.org/keywords/garra-rufa","display_name":"Garra rufa","score":0.9750000238418579},{"id":"https://openalex.org/keywords/hsp70","display_name":"HSP70","score":0.9490000009536743},{"id":"https://openalex.org/keywords/hsp60","display_name":"HSP60","score":0.921999990940094},{"id":"https://openalex.org/keywords/hsp90","display_name":"HSP90","score":0.9990000128746033},{"id":"https://openalex.org/keywords/hsc70","display_name":"Hsc70","score":0.8970000147819519},{"id":"https://openalex.org/keywords/grp75","display_name":"GRP75","score":0.9980000257492065},{"id":"https://openalex.org/keywords/protein-carbonyls","display_name":"protein carbonyls","score":0.949999988079071},{"id":"https://openalex.org/keywords/lipid-hydroperoxides","display_name":"lipid hydroperoxides","score":0.984000027179718},{"id":"https://openalex.org/keywords/cytoprotection","display_name":"cytoprotection","score":0.9110000133514404},{"id":"https://openalex.org/keywords/sublethal-temperature","display_name":"sublethal temperature","score":0.6660000085830688},{"id":"https://openalex.org/keywords/fish","display_name":"fish","score":0.3240000009536743}],"concepts":[{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.8899076581001282},{"id":"https://openalex.org/C205260736","wikidata":"https://www.wikidata.org/wiki/Q418939","display_name":"Heat shock protein","level":3,"score":0.8130539059638977},{"id":"https://openalex.org/C68991219","wikidata":"https://www.wikidata.org/wiki/Q419102","display_name":"Hsp70","level":4,"score":0.7342475652694702},{"id":"https://openalex.org/C146621620","wikidata":"https://www.wikidata.org/wiki/Q24771589","display_name":"HSP60","level":5,"score":0.6179884672164917},{"id":"https://openalex.org/C57600042","wikidata":"https://www.wikidata.org/wiki/Q227564","display_name":"Oxidative phosphorylation","level":2,"score":0.5365161299705505},{"id":"https://openalex.org/C2780829032","wikidata":"https://www.wikidata.org/wiki/Q898539","display_name":"Lipid peroxidation","level":3,"score":0.4760829508304596},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4720745086669922},{"id":"https://openalex.org/C2909208804","wikidata":"https://www.wikidata.org/wiki/Q127282","display_name":"Fish <Actinopterygii>","level":2,"score":0.45000317692756653},{"id":"https://openalex.org/C2780967304","wikidata":"https://www.wikidata.org/wiki/Q246156","display_name":"Cytoprotection","level":3,"score":0.41385766863822937},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.413571298122406},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3942943513393402},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3710952401161194},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3658367395401001},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.08617392182350159},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08053076267242432}],"mesh":[{"descriptor_ui":"D000220","descriptor_name":"Adaptation, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005399","descriptor_name":"Fishes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006360","descriptor_name":"Heat-Shock Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":7,"locations":[{"id":"doi:10.1016/j.redox.2014.10.003","doi":"https://doi.org/10.1016/j.redox.2014.10.003","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.redox.2014.10.003","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2213231714001098/pdf","source":{"id":"https://openalex.org/S2764928002","display_name":"Redox Biology","issn_l":"2213-2317","issn":["2213-2317"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Redox Biology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3196476","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4225528","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4225528","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4225528","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Redox Biol","raw_type":"Text"},{"id":"pmid:25462062","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25462062","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Redox biology","raw_type":"Journal Article"},{"id":"pmh:oai:acikerisim.duzce.edu.tr:20.500.12684/3770","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/20.500.12684/3770","pdf_url":null,"source":{"id":"https://openalex.org/S4377196355","display_name":"DSpace - D\u00fczce (Duzce University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I54001450","host_organization_name":"D\u00fczce \u00dcniversitesi","host_organization_lineage":["https://openalex.org/I54001450"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"article"},{"id":"pmh:oai:doaj.org/article:bd73ff5494334ac4a6297722fc5c6cae","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/bd73ff5494334ac4a6297722fc5c6cae","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Redox Biology, Vol 3, Iss C, Pp 25-28 (2014)","raw_type":"article"},{"id":"pmh:oai:openaccess.hacettepe.edu.tr:11655/19332","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11655/19332","pdf_url":null,"source":{"id":"https://openalex.org/S4306402578","display_name":"Hacettepe University Institutional Repository (hacettepe.edu.tr)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I66514158","host_organization_name":"Hacettepe University","host_organization_lineage":["https://openalex.org/I66514158"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.redox.2014.10.003","doi":"https://doi.org/10.1016/j.redox.2014.10.003","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.redox.2014.10.003","pdf_url":"https://www.sciencedirect.com/science/article/pii/S2213231714001098/pdf","source":{"id":"https://openalex.org/S2764928002","display_name":"Redox Biology","issn_l":"2213-2317","issn":["2213-2317"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Redox Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1369185036","display_name":null,"funder_award_id":"TD1304","funder_id":"https://openalex.org/F4320320366","funder_display_name":"European Cooperation in Science and Technology"},{"id":"https://openalex.org/G3037130325","display_name":null,"funder_award_id":"CM-1001","funder_id":"https://openalex.org/F4320320366","funder_display_name":"European Cooperation in Science and Technology"}],"funders":[{"id":"https://openalex.org/F4320320366","display_name":"European Cooperation in Science and Technology","ror":"https://ror.org/01bstzn19"},{"id":"https://openalex.org/F4320321727","display_name":"Opetus- ja Kulttuuriministeri\u00f6","ror":"https://ror.org/02w52zt87"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2049680397.pdf","grobid_xml":"https://content.openalex.org/works/W2049680397.grobid-xml"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W1491459594","https://openalex.org/W1964122029","https://openalex.org/W1966586204","https://openalex.org/W1969173372","https://openalex.org/W1975200549","https://openalex.org/W1982748225","https://openalex.org/W1984121313","https://openalex.org/W2003013739","https://openalex.org/W2008747059","https://openalex.org/W2008795567","https://openalex.org/W2013451267","https://openalex.org/W2023746083","https://openalex.org/W2030944037","https://openalex.org/W2032646952","https://openalex.org/W2056716184","https://openalex.org/W2059328741","https://openalex.org/W2072925339","https://openalex.org/W2075349874","https://openalex.org/W2079139546","https://openalex.org/W2081337134","https://openalex.org/W2090009773","https://openalex.org/W2106094592","https://openalex.org/W2115971557","https://openalex.org/W2140350410","https://openalex.org/W2166365175","https://openalex.org/W2343329845","https://openalex.org/W2599984638"],"related_works":["https://openalex.org/W2289385528","https://openalex.org/W1966586204","https://openalex.org/W2121899528","https://openalex.org/W4379194005","https://openalex.org/W3212997328","https://openalex.org/W2802185449","https://openalex.org/W1492305","https://openalex.org/W79750450","https://openalex.org/W7097734374","https://openalex.org/W4395462075"],"abstract_inverted_index":{"Heat":[0],"shock":[1],"proteins":[2,16],"(HSPs),":[3],"originally":[4],"identified":[5],"as":[6],"heat-inducible":[7],"gene":[8],"products,":[9],"are":[10,168],"a":[11,20,71,80,95],"family":[12],"of":[13,23,117,146],"highly":[14],"conserved":[15],"that":[17,115,165,179],"respond":[18],"to":[19,39,85,104],"wide":[21],"variety":[22],"stress":[24,34,56,67,188],"including":[25,149],"oxidative":[26,33,55,66,147,172,187],"stress.":[27,173],"Although":[28],"both":[29],"acute":[30],"and":[31,68,113,126,152,189],"chronic":[32],"have":[35],"been":[36],"well":[37],"demonstrated":[38],"induce":[40],"HSP":[41,49,166,182],"responses,":[42],"little":[43],"evidence":[44,178],"is":[45],"available":[46],"whether":[47],"increased":[48,181],"levels":[50,116,167,183],"provide":[51,177,184],"enhanced":[52],"protection":[53,185],"against":[54,186],"under":[57],"elevated":[58,134,162],"yet":[59],"sublethal":[60],"temperatures.":[61],"We":[62,89],"studied":[63,120],"relationships":[64],"between":[65],"HSPs":[69,121],"in":[70,94,107,130,133,157,160],"physiological":[72],"model":[73],"by":[74],"using":[75],"Garra":[76],"rufa":[77],"(doctor":[78],"fish),":[79],"fish":[81,91,131,158],"species":[82],"naturally":[83,92],"acclimatized":[84],"different":[86],"thermal":[87],"conditions.":[88],"compared":[90,137],"living":[93,106,132,159],"hot":[96],"spring":[97],"with":[98,138,171],"relatively":[99],"high":[100],"water":[101,110,135,141],"temperature":[102,111,136],"(34.4\u00b10.6\u00b0C)":[103],"those":[105],"normal":[108,139],"river":[109,140],"(25.4\u00b14.7\u00b0C),":[112],"found":[114],"all":[118],"the":[119,161],"(HSP70,":[122],"HSP60,":[123],"HSP90,":[124],"HSC70":[125],"GRP75)":[127],"were":[128,155],"higher":[129],"temperature.":[142],"In":[143],"contrast,":[144],"indicators":[145],"stress,":[148],"protein":[150],"carbonyls":[151],"lipid":[153],"hydroperoxides,":[154],"decreased":[156],"temperature,":[163],"indicating":[164],"inversely":[169],"associated":[170],"The":[174],"present":[175],"results":[176],"physiologically":[180],"enhance":[190],"cytoprotection.":[191]},"counts_by_year":[{"year":2026,"cited_by_count":13},{"year":2025,"cited_by_count":20},{"year":2024,"cited_by_count":15},{"year":2023,"cited_by_count":12},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":22},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":6}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}